Umenzi womgubo we-Amino Tadalafil Inombolo ye-CAS: 385769-84-6 Ubumsulwa obuyi-98% ubuncinane bezithako ezongezelelweyo
Ividiyo yeMveliso
Iiparamitha zeMveliso
| Igama lemveliso | I-Amino Tadalafil |
| Elinye igama | (6R,12aR)-2-Amino-6-(1,3-benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione;AminoTadalafil(6R,12Ar)-2-Amino-6-(1,3-Benzodioxol-5-Yl)-2,3,6,7,12,12A-Hexahydropyrazino[1',2':1,6]Pyrido[3,4-B]Indole-1,4-Dion e;(6R,12aR)-2-Amino-6-(benzo[d][1,3]dioxol-5-yl)-2,3,6,7,12,12a-hexahydropyrazino[1',2':1,6]pyrido[3,4-b]indol-1,4-dione;(6R,12aR)-2-amino-6-(benzo[d][1,3]dioxol-5-yl)-2,3,12,12a-tetrahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4(6H,7H)-dione |
| Inombolo ye-CAS | 385769-84-6 |
| Ifomula yemolekyuli | C21H18N4O4 |
| Ubunzima be-molecular | 390.39 |
| Ubunyulu | 98.0% |
| Inkangeleko | Umgubo omhlophe ukuya komhlophe ongekho mhlophe |
| Isicelo | Isongezelelo sokutya Izinto eziluhlaza |
Intshayelelo yemveliso
I-Amino Tadalafil yikhompawundi entsha, evela kwi-tadalafil, eyanda ukuthandwa kwicandelo lokungasebenzi kakuhle kwe-erectile (ED). Idibanisa i-amino acid ne-tadalafil, i-PDE5 inhibitor evunyiweyo yi-FDA esetyenziselwa ukunyanga i-ED. Isebenza ngokunyusa ukuhamba kwegazi ukuya kwi-penis, ivumela amadoda ukuba afikelele kwaye agcine ukuma. Ii-amino acid, kwelinye icala, zidlala indima ebalulekileyo kwimisebenzi eyahlukeneyo yomzimba, kubandakanya ukuveliswa kweeproteni, ezizizakhi zokwakha izicubu kunye namalungu omzimba. Ukudibana kwezi zithako zimbini kuyilelwe ukuphucula ukusebenza kweTadalafil ekunyangeni i-ED. Kwaye i-amino Tadalafil yinguqulelo ephuculweyo enekhono elimangalisayo, iphucula ukusebenza kunye nokuguquguquka kwento eyandulelayo. Ulwakhiwo lwayo lweekhemikhali luhlala lufana neTadalafil, kodwa ngokungeniswa kwamaqela e-amino, ifumana iimpawu ezikhethekileyo ezenza ukuba ivelele kwihlabathi lezemithi. Njenge-tadalafil, i-Amino Tadalafil isebenza ngokuthintela i-phosphodiesterase 5 (PDE5), i-enzyme enoxanduva lokuqhekeza i-cyclic guanosine monophosphate (cGMP) emzimbeni. I-cGMP yikhompawundi yendalo ekhuthaza ukuphumla kwemithambo yegazi, ngaloo ndlela inyusa ukuhamba kwegazi. Ngokuthintela i-PDE5, i-amino Tadalafil iqinisekisa ukuqokelelwa kwe-cGMP, ngaloo ndlela iphucula ukujikeleza kwegazi kunye nokuphucula ukuhamba kwegazi. Ukongeza, abaphandi bahlolisise amandla ayo okunceda ekunyangeni i-benign prostatic hyperplasia (BPH) ngokunyusa ukuhamba kwegazi kwi-prostate.
Uphawu
(1) Ubunyulu obuphezulu: I-Amino Tadalafil inokufumana iimveliso ezinyulu obuphezulu ngokusebenzisa iinkqubo zokucoca imveliso. Ubunyulu obuphezulu buthetha ukufumaneka ngcono kwezinto eziphilayo kunye neempendulo ezimbalwa ezingalunganga.
(2) Ukhuseleko: Ukhuseleko oluphezulu, zimbalwa iziphumo ezibi.
(3) Uzinzo: I-Amino Tadalafil izinzile kakuhle kwaye ingayigcina iyasebenza phantsi kweemeko ezahlukeneyo kunye neemeko zokugcina.
Izicelo
I-Amino Tadalafil sisithinteli se-PDE5 esineziphumo ezifanayo ze-pharmacological njenge-tadalafil. Ngokudibanisa ii-amino acids ne-tadalafil, i-amino Tadalafil kucingelwa ukuba iyasebenza ngakumbi ekunyangeni ukungasebenzi kakuhle kwe-erectile kune-tadalafil yodwa. Ii-amino acids zinokunceda ukuphucula ukujikeleza kwegazi kunye nokuxhasa ukusebenza kakuhle kwamayeza. Ukongeza, inokuphucula iimpawu zokungasebenzi kakuhle kwe-erectile (ED) ngokuthintela umsebenzi we-enzyme ye-PDE5 ukukhuthaza ukuhamba kwegazi kwizitho zokuzala zamadoda. Xa kuthelekiswa ne-tadalafil, i-amino Tadalafil inyibilika kancinci emzimbeni kwaye inokuvelisa iziphumo ezihlala ixesha elide. Oku kunika i-amino Tadalafil amandla amakhulu ekunyangeni i-ED.
