Umenzi womgubo weSunifiram Inombolo yeCAS: 314728-85-3 Ubumsulwa obuyi-99% ubuncinane bezithako ezongezelelweyo
Ividiyo yeMveliso
Iiparamitha zeMveliso
| Igama lemveliso | I-Sunifiram |
| Elinye igama | 1-(4-Benzoylpiperazin-1-yl)propan-1-one; 1-Benzoyl-4-(1-oxopropyl)piperazine |
| Inombolo ye-CAS | 314728-85-3 |
| Ifomula yemolekyuli | C14H18N2O2 |
| Ubunzima be-molecular | 246.30 |
| Ubunyulu | 99.0% |
| Inkangeleko | umgubo omhlophe wekristale |
| Ukupakisha | 1kg/ibhegi |
| Isicelo | ii-nootropics |
Intshayelelo yemveliso
I-Sunifiram yi-AMPA receptor agonist ephucula ukuhanjiswa kwemiqondiso kwii-AMPA receptors ebuchotsheni, ezihlala zicingelwa ukuba zidlala indima ebalulekileyo ekufundeni nasekukhumbuleni. Ngokuphucula umsebenzi wee-AMPA receptors, i-Sunifiram kucingelwa ukuba iphucula ubuchule bokufunda nokukhumbula ingqondo, ngelixa iphucula nokugxila kunye namandla engqondo. Ukongeza, isebenza ngokuvuselela umsebenzi wee-glutamate receptors kunye nokwandisa imveliso kunye nokukhululwa kwe-acetylcholine "yokufunda i-neurotransmitter". I-Sunifiram isebenza ngokuyintloko njenge-ampa factor, oko kuthetha ukuba ibopha kwii-receptors ze-glutamate zohlobo lwe-AMPA ebuchosheni emva kokuwela umqobo wegazi-ingqondo. Oku kukhuthaza ukuveliswa kwe-glutamate, i-neurotransmitter ebalulekileyo ebalulekileyo kwi-synaptic plasticity, okanye amandla e-nerve synapses ukuphendula ekwandeni okanye ekuncipha komsebenzi. Amanqanaba e-Glutamate abaluleke kakhulu kwi-hippocampus, inxalenye yengqondo edlala indima ebalulekileyo ekuhambeni kwendawo, ukwakheka kwememori, kunye nokugcinwa. Amanqanaba e-glutamate afanelekileyo abalulekile ekuphuculweni kwexesha elide okanye ekuphuculweni okuhlala ixesha elide kwemiqondiso phakathi kwee-neurons. Amandla abalulekile. Uninzi lwamandla okuphucula ingqondo eSunifilaram ekugqibeleni asebenza ngokwandisa amandla emiqondiso ye-neural kweli candelo lobuchopho.
Uphawu
(1) Ubunyulu obuphezulu: I-Sunifiram inokufumana iimveliso ezinyulu obuphezulu ngeenkqubo zemveliso ezicociweyo. Ubunyulu obuphezulu buthetha ukufumaneka ngcono kwezinto eziphilayo kunye neempendulo ezimbalwa ezingalunganga.
(2) Ukhuseleko: I-Sunifiram ibonakaliswe ikhuselekile emzimbeni womntu.
(3) Uzinzo: I-Sunifiram izinzile kakuhle kwaye inokugcina umsebenzi wayo kunye nesiphumo phantsi kweemeko ezahlukeneyo kunye neemeko zokugcina.
Izicelo
I-Sunifiram sisithambisi se-neuroplasticity, esikwafumaneka njengesongezelelo sokutya, esicingelwa ukuba siphucula ukusebenza kwengqondo nokuphucula ukufunda kunye nenkumbulo. Isebenza ngokucubungula ii-AMPA receptors ebuchotsheni. I-AMPA yi-neurotransmitter ebandakanyeka kunxibelelwano olukhawulezayo phakathi kweeseli kwinkqubo yemithambo-luvo. Iphucula kakhulu isantya sokufunda, ukugcinwa kwememori kunye nokukhumbula, kunye nokuphucula ukugxila, ukukhuthazeka kunye nokucaca kwengqondo.
