I-Compound 7P umenzi we-powder CAS No.: 1890208-58-8 99% ubumsulwa min. zokongeza izithako
Ividiyo yeMveliso
IiParameters zeMveliso
| Igama lemveliso | I-Compound 7P |
| Elinye igama | Compound7P;2- [(2-methoxyphenyl)[(4-methylphenyl)sulfonyl]amino]-N-(4-methoxy-3-pyridinyl)acetamide; 2-(N-(2-methoxyphenyl) -4-methylphenylsulfonamido)-N-(4-methoxypyridin-3-yl)acetamide |
| Inombolo yeCAS. | 1890208-58-8 |
| Ifomula yemolekyuli | I-C22H23N3O5S |
| Ubunzima bemolekyuli | 441.51 |
| Ubunyulu | 99.0% |
| Imbonakalo | Umgubo omhlophe |
| Isicelo | Nootropic |
Intshayelelo yemveliso
ICompound 7P ibhekisa kwikhompawundi ethile yendalo equlathe iiathom zekhabhoni ezisixhenxe. Kwimichiza yezinto eziphilayo, ikhabhoni yinto ebalulekileyo kuba inokwenza izibophelelo ezizinzileyo kunye nezinye iiathomu, kubandakanywa iiathomu zekhabhoni, ukwenza iimolekyuli ezintsonkothileyo. Ezi molekyuli zinokuba neepropati ezahlukeneyo kunye nemisebenzi, okwenza i-carbon-based compounds ibe yibhloko yokwakha ubomi. Kwiimodeli zezilwanyana zokulimala kwe-optic nerve, i-compound 7p yaboniswa ukuba ikhuthaze ukukhula kwe-GAP-43-positive axons, ebonisa ukuba umsebenzi wokukhula kwe-neurite we-compound 7p in vitro uguqulela ekuvuseleleni ukuvuselelwa kwe-axonal kwi-vivo. I-Compound 7P powder iyimpuphu emhlophe emhlophe eveliswa njenge-tandem compound yokuchonga i-dual-acting thromboxane receptor antagonist inhibitors. Enyanisweni, i-compound 7p ibonise ukukhetha kwe-prostaglandin I2 synthase (PTGIS, CYP8A1) ngokumalunga ne-thromboxane synthase (CYP5A1). I-nootropic compound ye-7P powder ikhuthaza ukukhula kwe-Gap-43-positive axons, ngaloo ndlela ivuselela ukuvuselelwa kwe-axonal emzimbeni. Umgangatho ophezulu we-Complex 7p yenzelwe ukuphucula ulungelelwaniso, ukuphucula isimo sengqondo kunye nokunceda ukulwa nokudinwa. Ikwanqanda i-oxidation yengqondo kwaye inceda ukulwa nomonakalo wobuchopho obangelwa kukusela utywala.
Uphawu
(1) Ukucoceka okuphezulu: I-Compound 7P inokufumana iimveliso ezicocekileyo ngokusebenzisa iinkqubo zokuvelisa eziphuculweyo. Ukucoceka okuphezulu kuthetha ukuba ngcono kwe-bioavailability kunye neempendulo ezimbalwa ezimbi.
(2) Ukhuseleko: I-Compound 7P ibonakaliswe ukuba ikhuselekile kumzimba womntu.
(3) Ukuzinza: I-Compound 7P inozinzo oluhle kwaye inokugcina umsebenzi wayo kunye nesiphumo phantsi kweemeko ezahlukeneyo kunye neemeko zokugcina.
Usetyenziso
I-Compound 7p iphucula ukuphuma kwe-neurite ye-neuron ephuculweyo ephuma kwi-hippocampus, i-cerebral cortex, kunye ne-retina kwaye ibangela ukuvuselelwa kwe-optic nerve kwiimodeli zezilwanyana zokulimala kwe-optic nerve. Ikwaphucula ulungelelwaniso, iphatha ukonakala kwengqondo okunxulumene notywala, kwaye inqande i-oxidation ejikeleze ingqondo. Kwakhona kunceda ukuphucula isimo sengqondo kunye nokulwa nokudinwa.
