Umenzi womgubo weDeazaflavin Inombolo yeCAS: 26908-38-3 Ubumsulwa obuyi-99.0% ubuncinane bezithako ezongezelelweyo
Ividiyo yeMveliso
Iiparamitha zeMveliso
| Igama lemveliso | I-Deazaflavin |
| Elinye igama | i-Pyrimido[4,5-b]quinoline-2,4(1H,3H)-dione; 5-iDeazaflavin; I-1H-Pyrimido[4,5-b]chinolin-2,4-dion; |
| Inombolo ye-CAS | 26908-38-3 |
| Ifomula yemolekyuli | C11H7N3O2 |
| Ubunzima be-molecular | 213.192 |
| Ubunyulu | 99.0 % |
| Inkangeleko | umgubo otyheli okhanyayo |
| Ukupakisha | 1kg/ibhegi, 20kg ngegubu ngalinye |
| Isicelo | Ukuthintela ukwaluphala, kuphucula impilo yentliziyo ye-cerebrovascular |
Intshayelelo yemveliso
I-Deazaflavin powder yi-pyridine pyrimidine compound ephuma kwi-flavin, eyaziwa ngokuba yi-vitamin B2. Yenziwe ngokufaka iqela le-aza eliqulethe i-nitrogen N element kwindawo yesi-5 kunye ne-deaza equlethe i-carbon C element. Olu tshintsho lukhethekileyo lwe-deaza zenza ukuba i-5-deazaflavin backbone isebenze ngendlela efanayo ne-vitamin B3 backbone /NAD+. Okubangela umdla kukuba, uthotho oluphambili lwe-vitamin B2 luzinzile ngokweekhemikhali, kwaye i-5-deazaflavin inee-substituents ezininzi ezinokuguqulwa. I-5-Deazaflavin powder ke ngoko ineempawu ezahlukeneyo zeekhemikhali kunye nezomzimba ezenza ukuba ibe yi-compound ekhangayo kungekuphela nje njenge-antioxidant enamandla enokunceda ukukhusela iiseli kuxinzelelo lwe-oxidative. Phakathi kwazo, ukusetyenziswa kwe-5-deazaflavin powder I-5-deazaflavin powder sisithako esichasene nokwaluphala, esinokukhuthaza ukuveliswa kwe-NAD + emzimbeni. I-NAD + yi-coenzyme edlala indima ebalulekileyo kwi-metabolism yamandla kunye nokulungiswa kweeseli. Idlala indima ebalulekileyo ekuncedeni ukucothisa inkqubo yokwaluphala kweeseli. Ukongeza, i-5-deazoflavin ingasetyenziselwa ukwenziwa kwee-nucleosides kunye nee-nucleotides ezithile, ezizizinto ezisisiseko ze-DNA kunye ne-RNA. Ulwakhiwo lwayo olukhethekileyo lweekhemikhali luyenza ibe luncedo ekuphuhlisweni kwamayeza amatsha kunye nonyango. Umgubo we-5-Deazaflavin ubonakalisiwe ukuba unezicelo zonyango ezinokubakho kunyango lwezifo ezahlukeneyo.
Uphawu
(1) Uzinzo: I-5-Deazaflavin inozinzo olungcono kwaye ihlala ixesha elide eshelufini, nto leyo eyenza ukuba ibe lukhetho olulula ngakumbi kubavelisi bezongezo kunye nabathengi.
(2) I-Redox potential: I-5-deazaflavin ine-redox potential engalunganga ngakumbi, nto leyo eyenza ukuba ithathe inxaxheba kuluhlu olubanzi lweempendulo ze-biochemical.
(3) I-Complement: I-5-deazaflavin yongeza ezinye ii-coenzymes, ezifana ne-flavin kunye ne-nicotinamide, ukuze kwenziwe imetabolism yeseli igqibelele kwaye isebenze ngakumbi.
(4) Iimpawu ze-Photocatalytic: I-5-deazaflavine ibonakalisiwe ukuba ineempawu ze-photocatalytic, ezinokuba nezicelo ezinokubakho kumashishini ahlukeneyo.
Izicelo
Ukuziqhelanisa kwe-5-deazaflavin kunye namandla eemveliso zayo eziphuma kuyo kuzenza zibe yimichiza enomdla yophando nophuhliso olongezelelekileyo. Umsebenzi wayo ofana nokukwazi kwe-/NAD+ kunye nokuziqhelanisa kwayo nokuguqula ngeendlela ezahlukeneyo kunokuba nezicelo ezininzi kwiindawo ezahlukeneyo ezifana nonyango oluhlala ixesha elide kunye nokuveliswa kwamandla. Olunye uphando lubonisa ukuba i-5-deazaflavin inokuba neempawu zokuqinisa amasosha omzimba kwaye inokunceda ukuxhasa inkqubo yomzimba yokuzikhusela esempilweni.
