Umenzi womgubo we-5-Aminolevulinic acid phosphate (ALA) Inombolo ye-CAS: 868074-65-1 Ubumsulwa obuyi-98% ubuncinane ngexabiso elihle
Ividiyo yeMveliso
Iiparamitha zeMveliso
| Igama lemveliso | I-phosphate ye-5-Aminolevulinic acid |
| Elinye igama | i-5-amino-4-oxopentanoic acid, i-phosphorus acid; i-5-aminolevulinic acid phosphate, i-5-ALA phosphate; i-5-Amino-4-oxopentanoic acid phosphate; I-phosphate ye-5-Aminolevulinic acid; I-asidi yePentanoic, i-5-amino-4-oxo-, i-phosphate |
| Inombolo ye-CAS | 868074-65-1 |
| Ifomula yemolekyuli | C5H12NO7P |
| Ubunzima be-molecular | 229.13 |
| Ubunyulu | 98.0% |
| Inkangeleko | Umgubo omhlophe ukuya komhlophe ongekho mhlophe |
| Isicelo | Isongezelelo sokutya Izinto eziluhlaza |
Intshayelelo yemveliso
I-5-Aminolevulinic acid phosphate, eyaziwa ngokuba yi-ALA phosphate, yeyona nto iphambili kwi-biosynthesis ye-heme, into ebalulekileyo kwi-hemoglobin, i-myoglobin kunye nee-enzymes ezahlukeneyo emzimbeni. I-ALA phosphate yenziwa ngothotho lwee-enzyme reactions ezenzeka ikakhulu kwi-mitochondria, izitishi zamandla zeeseli zethu. Yenziwa ngokuxinana kwe-glycine kunye ne-succinyl-CoA, ezizizinto ezibalulekileyo zeendlela zethu ze-metabolic. Ukwenziwa kwe-heme kubaluleke kakhulu kwimpilo yabantu njengoko le molekyuli idlala indima ebalulekileyo ekuthuthweni kwe-oksijini, ukuhanjiswa kwee-electron kunye nokususwa kwetyhefu emzimbeni. I-ALA phosphate linyathelo elithintela izinga kwi-heme biosynthesis. Ngothotho lweenguqu ze-enzyme, i-ALA phosphate iguqulwa ibe yi-porphobilinogen, imolekyuli eyandulela i-heme.
Uphawu
(1) Ubunyulu obuphezulu: I-5-aminolevulinic acid phosphate inokufunyanwa njengeemveliso ezinyulu obuphezulu ngeenkqubo zokuvelisa ezicociweyo. Ubunyulu obuphezulu buthetha ukufumaneka ngcono kwezinto eziphilayo kunye neempendulo ezimbalwa ezingalunganga.
(2) Ukhuseleko: I-5-aminolevulinic acid phosphate ibonakalisiwe ikhuselekile emzimbeni womntu.
(3) Uzinzo: I-5-Aminolevulinic acid phosphate inozinzo oluhle kwaye inokugcina umsebenzi wayo kunye nesiphumo phantsi kweemeko ezahlukeneyo kunye neemeko zokugcina.
Izicelo
I-5-Aminolevulinic acid phosphate (5-ALA) yi-amino acid yendalo kwaye yinto esebenzayo ekhoyo kakhulu ebomini. Yindlela yokuqala yeekhompawundi ze-porphyrin kunye nesiseko seempendulo ze-biochemical ze-chlorophyll, i-heme kunye ne-vitamin B12. I-5-ALA phosphate sisiphumo se-5-ALA kwaye sifunxwa kwaye sisetyenziswe lula ngumzimba. Ukufakwa ngomlomo kwe-5-ALA phosphate kungenza i-myoglobin synthase isebenze, kukhawulezise ukwenziwa kwe-myoglobin emzimbeni womntu, kwandise amafutha emisipha, kwaye kunciphise amafutha. Ukongeza, i-5-ALA inokuphucula umsebenzi we-mitochondria kwiiseli zabantu, ikhuthaze imetabolism, iphucule ukusebenza kakuhle kokufumana amandla, kwaye inciphise iswekile yegazi kunye nee-lipids zegazi. Ukuqukumbela, i-5-ALA phosphate iluncedo kakhulu kwimpilo.
