Umenzi womgubo wePalmitoylethanolamide (PEA Granule) Inombolo yeCAS: 544-31-0 Ubumsulwa obuyi-97% ubuncinci bezithako ezongezelelweyo
Iiparamitha zeMveliso
| Igama lemveliso | I-PEA |
| Elinye igama | I-N-(2-HYDROXYETHYL)HEXADECANAMIDE; I-N-HEXADECANOYLETHANOLAMINE; I-PEAPALMIDROL; I-Palmitylethanolamide; I-Palmitoylethanolamide |
| Inombolo ye-CAS | 544-31-0 |
| Ifomula yemolekyuli | C18H37NO2 |
| Ubunzima be-molecular | 299.49 |
| Ubunyulu | 97.0% |
| Inkangeleko | Umgubo omhlophe ocoliweyo |
| Ukupakisha | 1kg/ibhegi, 25Kg/ idrama |
| Isicelo | Izinto ezisetyenziswa kwiimveliso zonyango |
Intshayelelo yemveliso
I-Palmitoylethanolamide yimolekyuli ye-lipid messenger eyafunyanwa okokuqala ngasekupheleni kweminyaka yoo-1950. Ikwiqela leekhompawundi ezibizwa ngokuba yi-endocannabinoids, ezizinto zendalo ezisebenzisana nenkqubo ye-endocannabinoid yomzimba. Ngokungafaniyo nezinye ii-cannabinoids ezifana ne-THC ezifumaneka kwisityalo se-cannabis, i-PEA ayisebenzi engqondweni kwaye ayivelisi ziphumo zitshintsha ingqondo. Inkqubo ye-endocannabinoid (ECS) yinethiwekhi entsonkothileyo yee-receptors kunye nee-endocannabinoids ezifumaneka kuwo wonke umzimba. Idlala indima ebalulekileyo ekulawuleni iinkqubo ezahlukeneyo zomzimba, kubandakanya ukuqonda intlungu, ukudumba, kunye neemvakalelo. I-PEA isebenza njenge-endogenous ligand ye-receptor ethile kwi-ECS ebizwa ngokuba yi-peroxisome proliferator-activated receptor-α (PPAR-α). Ngokusebenzisa le receptor, i-PEA isebenzisa iziphumo zayo zokulwa nokuvuvukala kunye ne-analgesic. Izifundo zibonisa ukuba i-Palmitoylethanolamide inokunceda ukulawula iintlungu ezingapheliyo, kubandakanya iintlungu ze-neuropathic kunye ne-inflammatory. Isebenza ngokunciphisa ukukhululwa kwezinto ezibangela ukuvuvukala kunye nokulawula ukusebenza kweeseli zomzimba ezibandakanyekayo kwimpendulo yokuvuvukala. Izilingo ezininzi zeklinikhi zibonise ukusebenza kakuhle kwe-PEA ekunciphiseni ubukhali beentlungu kunye nokuphucula umgangatho wobomi kwizigulane ezineengxaki ezahlukeneyo zeentlungu ezingapheliyo.
Uphawu
(1) Ubunyulu obuphezulu: I-PEA inokufumana iimveliso ezinyulu obuphezulu ngokusebenzisa iinkqubo zemveliso zokucoca. Ubunyulu obuphezulu buthetha ukufumaneka ngcono kwezinto eziphilayo kunye neempendulo ezimbalwa ezingalunganga.
(2) Ukhuseleko: Ukhuseleko oluphezulu, zimbalwa iziphumo ezibi.
(3) Uzinzo: I-PEA izinzile kakuhle kwaye inokugcina umsebenzi wayo kunye nesiphumo phantsi kweemeko ezahlukeneyo kunye neemeko zokugcina.
Izicelo
Isetyenziswa njengesongezelelo sokutya, iPalmitoylethanolamide yi-fatty acid amide yendalo enefuthe lokulwa nokuvuvukala, ukuthomalalisa iintlungu, kunye nokukhusela imithambo-luvo ngokuguqula inkqubo ye-endocannabinoid. Iingenelo zayo ezinokubakho zokulawula iintlungu ezingapheliyo kunye nezinye iimeko zempilo zenza ukuba ibe lukhetho olunomdla kubantu abafuna ezinye iindlela zendalo. Ukongeza, i-PEA ikwayindlela yokudibanisa i-organic synthesis kunye ne-pharmaceutical intermediate, engasetyenziswa kuphando lwelabhoratri kunye neenkqubo zophuhliso kunye nophando lwamayeza eekhemikhali kunye neenkqubo zophuhliso.
