Umenzi womgubo weBeta-Nicotinamide adenine dinucleotide disodium salt (NADH) Inombolo yeCAS: 606-68-8 Ubumsulwa obuyi-95% ubuncinci. Izithako zezongezo ezininzi
Iiparamitha zeMveliso
| Igama lemveliso | I-NADH |
| Elinye igama | i-eta-d-ribofuranosyl-3-pyridinecarboxamide,ityuwa ye-disodium; i-BETA-NICOTINAMIDEADENINEDINUCLEOTIDE,IFOMU ENCITSHISIWEYOI-DISODIUMSALT; i-BETA-NICOTINAMIDE-ADENINEDINUCLEOTIDE,INCITSHISIWEYOI-2NA; i-BETA-NICOTINAMIDEADENINEDINUCLEOTIDEREDUDEDIDISODIUMSALT; i-BETA-NICOTINAMIDEADENINEDINUCLEOTIDE,DISODIUMSALT; i-beta-Nicotinamideadeninedinucleotidedisodiumsalthydrate; i-eta-d-ribofuranosyl-3-pyridinecarboxamide,ityuwa ye-disodiumbeta-nicotinamideadeninedinucleotide,ityuwa ye-disodium,i-hydratebeta-nicotinamideadeninedinucleotidedisodiumsalt,i-trihydrate; i-NICOTINAMIDEADENINEDINUCLEOTIDE(INCITSHISIWEYOI-DISODIUMSALT) |
| Inombolo ye-CAS | 606-68-8 |
| Ifomula yemolekyuli | C21H30N7NaO14P2 |
| Ubunzima be-molecular | 689.44 |
| Ubunyulu | 95% |
| Inkangeleko | Umgubo omhlophe ukuya kotyheli |
| Isicelo | Isongezelelo sokutya Izinto eziluhlaza |
Intshayelelo yemveliso
I-NADH yi-biomolecule ebandakanyeka kwi-metabolism yamandla angaphakathi kweseli. Yi-coenzyme ebalulekileyo ekuguquleni iimolekyuli zokutya ezifana ne-glucose kunye ne-fatty acids zibe yi-ATP energy. I-NADH yindlela encitshisiweyo ye-NAD+ kwaye i-NAD+ yindlela e-oxidized. Yenziwa ngokwamkela ii-electron kunye neeproton, inkqubo ebalulekileyo kwiimpendulo ezininzi ze-biochemical. I-NADH idlala indima ebalulekileyo kwi-metabolism yamandla ngokubonelela ngee-electron ukukhuthaza ii-redox reactions zangaphakathi kweseli ukuvelisa amandla e-ATP. Ukongeza ekuthatheni inxaxheba kwi-metabolism yamandla, i-NADH ikwabandakanyeka kwezinye iinkqubo ezininzi ezibalulekileyo zebhayoloji, ezifana ne-apoptosis, ukulungiswa kwe-DNA, ukwahluka kweeseli, njl. Indima ye-NADH kwezi nkqubo inokwahluka kwindima yayo kwi-metabolism yamandla. I-NADH idlala indima ebalulekileyo kwi-metabolism yeseli kunye nemisebenzi yobomi. Ayingomdlali obalulekileyo kwi-metabolism yamandla kuphela, kodwa ikwathatha inxaxheba nakwezinye iinkqubo ezininzi ezibalulekileyo zebhayoloji kwaye inezicelo ezininzi.
Uphawu
(1) Ubunyulu obuphezulu: I-NADH inokufumana iimveliso ezinyulu obuphezulu ngenkqubo yemveliso ecociweyo. Ubunyulu obuphezulu buthetha ukufumaneka ngcono kwezinto eziphilayo kunye neempendulo ezimbalwa ezingalunganga.
(2) Iipropati ze-Antioxidant: I-NADH ineempawu ze-antioxidant ezinamandla kwaye inokukhusela iiseli kumonakalo obangelwa luxinzelelo lwe-oxidative kunye nee-free radicals.
(3) Uzinzo: I-NADH izinzile kakuhle kwaye inokugcina umsebenzi wayo kunye nesiphumo phantsi kweemeko ezahlukeneyo kunye neemeko zokugcina.
Izicelo
Okwangoku, i-NADH isetyenziswa kakhulu kwiimveliso zesondlo, izinto zokuthambisa nakwezinye iindawo.
Kwicandelo lesondlo, i-NADH isetyenziswa njengeemveliso zempilo kunye nezongezo zesondlo ukwandisa amanqanaba amandla omzimba, ukuphucula ukusebenza kwenkqubo yomzimba yokuzikhusela, kunye nokukhuthaza impilo iyonke. Ukongeza, i-NADH isetyenziswa kakhulu kwishishini lezithambiso njengesithako sokulwa nokwaluphala, inceda ekuchaseni umonakalo we-free radicals, ukunciphisa imigca emincinci kunye nemibimbi, kunye nokuphucula ukuthamba kolusu kunye nokukhazimla. Ngokuqhubeka kophando malunga nendlela esebenza ngayo i-NADH kunye nokwandiswa okuqhubekayo kobubanzi besicelo sayo, amathuba okusetyenziswa kwe-NADH aya ethembisa ngakumbi. Kwixesha elizayo, kulindeleke ukuba i-NADH idlale indima ebaluleke ngakumbi kwisondlo, kwizithambiso nakwezinye iinkalo.
