Umenzi weNooglutyl powder Inombolo yeCAS: 112193-35-8 Ubumsulwa obuyi-99.0% ubuncinane bezithako ezongezelelweyo
Iiparamitha zeMveliso
| Igama lemveliso | I-Nooglutyl |
| Elinye igama | I-Nooglutil; I-N-[(5-Hydroxy-3-pyridinyl)carbonyl]-L-glutamicacid;N-[(5-Hydroxypyridin-3-yl)carbonyl]-L-glutamicacid; I-ONK-10; I-L-GlutaMicacid,N-[(5-hydroxy-3-pyridinyl)carbonyl]-; I-N-(5-hydroxynicotinoyl)-L-glutamicacid |
| Inombolo ye-CAS | 112193-35-8 |
| Ifomula yemolekyuli | C11H12N2O6 |
| Ubunzima be-molecular | 268.22 |
| Ubunyulu | 99.0% |
| Inkangeleko | Umgubo omhlophe okanye ophantse ube mhlophe |
| Isicelo | Isongezelelo sokutya Izinto eziluhlaza |
Intshayelelo yemveliso
I-Nooglutyl, yikhompawundi eyenziweyo eyinxalenye yosapho lwe-nootropics oluvela kwi-racemate. Yaqala ukuphuhliswa eRashiya ngeminyaka yoo-1980 kwaye ukususela ngoko iye yathandwa ngabasebenzisi abafuna ukuphucula ingqondo. I-Nooglutyl ithathwa njengesixhobo sokuphucula imetabolism yengqondo, oko kuthetha ukuba kucingelwa ukuba iphucula ukusebenza kwengqondo ngokwandisa imveliso yamandla kunye nemetabolism engqondweni. Kucingelwa ukuba iphucula ukwakheka kwememori kunye nokugcinwa kwayo ngokukhuthaza ukukhululwa kwe-neurotransmitter acetylcholine engqondweni. Ngenxa yoko, abasebenzisi bafumana ulwazi oluphuculweyo, ukugxila okuphuculweyo, kunye nokukhumbula ngokukhawuleza.
Ukongeza, iNooglutyl kucingelwa ukuba ikhuthaza ukukhululwa kwe-glutamate, i-neurotransmitter evuselelayo ebalulekileyo ekuphuculeni umsebenzi wokuqonda. Ngokunyusa amanqanaba e-glutamate, iNooglutyl iphucula imetabolism yamandla obuchopho, ngaloo ndlela iphucula ukuphaphama, ukucaca kwengqondo, kunye nokusebenza kwengqondo iyonke. Iziphumo ezivuselelayo zeNooglutyl kwii-receptors ze-glutamate zinokunceda ukuphucula ukugxila kunye nokugxila. Ngokuguqula inkqubo ye-glutamate yengqondo, le nootropic inokunceda abantu boyise ukuphazamiseka kwaye bagcine ingqalelo eqhubekayo, ngaloo ndlela bonyusa imveliso kunye nokusebenza kwimisebenzi eyahlukeneyo.
Uphawu
(1) Ubunyulu obuphezulu: I-Nooglutyl inokufumana iimveliso ezinyulu obuphezulu ngokusebenzisa ukukhupha kwendalo kunye nenkqubo yokuvelisa izinto ezincinci. Ubunyulu obuphezulu buthetha ukufumaneka ngcono kwezinto eziphilayo kunye neempendulo ezimbalwa ezimbi.
(2) Ukhuseleko: I-Nooglutyl yimveliso yendalo ebonakaliswe ikhuselekile ebantwini. Ngaphakathi koluhlu lwedosi, ayinatyhefu okanye iziphumo ebezingalindelekanga.
(3) Uzinzo: I-Nooglutyl inozinzo oluhle kwaye ingayigcina iyasebenza phantsi kweemeko ezahlukeneyo zokusingqongileyo kunye nokugcinwa kwayo.
(4) Kulula ukufunxa: I-Nooglutyl inokufunxwa ngokukhawuleza ngumzimba womntu, ingene kwi-blood circulation nge-intestinal tract, ize isasazwe kwiithishu kunye namalungu ahlukeneyo.
Izicelo
I-Nooglutyl lilungu losapho lwe-racemate kwaye ibonakalise ithemba elikhulu ekuphuculeni ukusebenza kwengqondo nokubonelela ngeenzuzo ze-nootropic. Amandla ayo okwandisa inkumbulo, amandla engqondo, ukugxila, kunye nokukhusela uxinzelelo lwe-oxidative kwenza kube lukhetho olunomdla kubantu abafuna ukuphucula ukusebenza kwengqondo. Uphando lubonisa ukuba isakhiwo sekhemikhali esikhethekileyo se-Nooglutyl sinokuba sikhusela imithambo-luvo. Kucingelwa ukuba sinciphisa uxinzelelo lwe-oxidative, sithintele umonakalo weeseli zobuchopho obangelwa zii-free radicals, kwaye sincede ekugcineni nasekuvuseleleni unxibelelwano lwe-neuronal. Ezi ziphumo zinokuthi zikhusele imithambo-luvo zenza i-Nooglutyl ibe lukhetho olunomdla kubantu abaxhalabileyo malunga nokuncipha kwengqondo okunxulumene nobudala okanye isifo semithambo-luvo.
