I-N-Boc-O-Benzyl-D-serine powder umenzi we-CAS No.: 47173-80-8 98% ubumsulwa min.kubaPhakathi
IiParameters zeMveliso
| Igama lemveliso | N-Boc-O-Benzyl-D-serine |
| Elinye igama | N-Boc-O-benzyl-D-serine; I-Boc-O-benzyl-D-serine; O-Benzyl-N-(tert-butoxycarbonyl)-D-serine; I-Boc-(R) -2-amino-3-benzyloxypropionic acid; I-Boc-D-Ser(Bzl)-OH;Nat.-Boc-O-benzyl-D-serine; I-N-tert-butyloxycarbonyl-O-benzyl-D-serine; I-Nalpha-t-butoxycarbonyl-O-benzyl-D-serine; |
| Inombolo yeCAS. | 47173-80-8 |
| Ifomula yemolekyuli | C15H21NO5 |
| Ubunzima bemolekyuli | 295.33 |
| Ubunyulu | 98% |
| Ukupakisha | 1kg/ibhegi;25kg/igubu |
| Isicelo | Abaphakathi |
Intshayelelo yemveliso
I-N-Boc-O-Benzyl-D-serine yikhompawundi eye yafumana ingqwalasela ebalulekileyo kwintsimi ye-organic chemistry kunye nophando lwamachiza.Le khompawundi, ekwabizwa ngokuba yi-Boc-D-serine, iphuma kwi-amino acid D-serine kwaye isetyenziswa ngokubanzi ekudibaneni kwamayeza ahlukeneyo kunye neeathom ze-bioactive.I-N-Boc-O-Benzyl-D-serine ngumgubo wekristale omhlophe ukuya komhlophe onyibilikayo kancinci emanzini kwaye unyibilika kwizinyibilikisi zendalo ezifana nemethanol kunye ne-ethanol.Iphuma kwi-D-serine, eyi-amino acid engeyiyo iproteinogenic edlala indima ebalulekileyo kwinkqubo ye-nervous central njenge-co-agonist ye-N-methyl-D-aspartate (NMDA) receptor.I-N-Boc (i-tert-butoxycarbonyl) kunye namaqela e-O-Benzyl kwi-compound isebenza njengamaqela akhuselayo, evumela ukuguqulwa okukhethiweyo kwe-amino acid ngexesha le-chemical synthesis.N-Boc-O-Benzyl-D-serine ngokuyinhloko isetyenziswa njenge ibhloko yokwakha kwi-synthesis ye-peptides kunye ne-peptidomimetics.Iipeptides ngamatyathanga amafutshane ee-amino acids ezidlala iindima ezahlukeneyo kwiinkqubo zebhayoloji kwaye zinomdla omkhulu ekufumaneni ichiza nophuhliso.Ngokudibanisa i-N-Boc-O-Benzyl-D-serine kwii-peptide ezilandelelanayo, iikhemisti ziyakwazi ukulungelelanisa iimpawu kunye nemisebenzi yeepeptide ezibangelwayo, okwenza kube sisixhobo esibalulekileyo ekuyilweni kwee-agent zamachiza ezinoveli.Ngaphezu koko, i-N-Boc-O-Benzyl-D-serine iqeshwe ekulungiseleleni i-pharmaceutical intermediates kunye nezithako ezisebenzayo zamachiza (APIs).I-reactivity yayo eguquguqukayo kunye nokuhambelana neenguqu ezahlukeneyo zeekhemikhali kuyenza ibe yinto efunwayo kwi-synthesis yee-molecule ze-organic eziyinkimbinkimbi kunye namandla onyango.
Uphawu
(1) Ukucoceka okuphezulu: I-N-Boc-O-Benzyl-D-serine inokufumana iimveliso ezicocekileyo ngokucokisa iinkqubo zokuvelisa.Ukucoceka okuphezulu kuthetha ukuba ngcono kwe-bioavailability kunye neempendulo ezimbalwa ezimbi.
(2) Ukhuseleko: Ukhuseleko oluphezulu, zimbalwa izenzo ezibi.
(3) Ukuzinza: I-N-Boc-O-Benzyl-D-serine inozinzo oluhle kwaye inokugcina umsebenzi wayo kunye nesiphumo phantsi kweemeko ezahlukeneyo kunye neemeko zokugcina.
Usetyenziso
Ukudityaniswa kwe-N-Boc-O-Benzyl-D-serine kwiimolekyuli zamachiza kuye kwaboniswa ukunika izinto ezinqwenelekayo ze-pharmacokinetic kunye ne-pharmacodynamic.I-Peptidomimetics evela kwi-N-Boc-O-Benzyl-D-serine ibonise ukuzinza okuphuculweyo, i-bioavailability, kunye nokuchaneka okujoliswe kuyo, okwenza ukuba abaviwa abathembisayo kunyango lwezifo ezahlukeneyo, kubandakanywa umhlaza, izifo ezithathelwanayo, kunye nokuphazamiseka kwengqondo.Ngaphezu koko, amandla ukuguqula ngokukhethiweyo i-N-Boc-O-Benzyl-D-serine moiety ivumela ukulungiswa kakuhle kwabaviwa beziyobisi, ukwandisa ukusebenza kwabo kunye neeprofayili zokhuseleko.
