J-147 umenzi we-powder CAS No.: 1146963-51-0 99.0% ubumsulwa min.zokongeza izithako
IiParameters zeMveliso
| Igama lemveliso | 2,2,2-Trifluoroacetic acid 1-(2,4-DiMethylphenyl)-2-[(3-Methoxyphenyl)Methylene]hydrazide] |
| Elinye igama | I-J-147, i-J147 |
| Inombolo yeCAS. | 1146963-51-0 |
| Ifomula yemolekyuli | I-C18H17F3N2O2 |
| Ubunzima bemolekyuli | 350.33 |
| Ubunyulu | 99% |
| Imbonakalo | Umgubo omhlophe |
| Ukupakisha | 1kg ibhegi nganye |
| Isicelo | nootropics |
Intshayelelo yeMveliso
I-J-147 yi-neuroprotectant enamandla kakhulu yomlomo ephuma ngokuyinhloko kwi-curcumin, isithako esisebenzayo kwi-turmeric.Ngokungafaniyo ne-curcumin, inqumla umqobo wegazi-ingqondo ngempumelelo kakhulu.Phakathi kwabo, i-J-147 isebenza ngokubophelela kwi-ATP synthase.Ukuvelisa ngokugqithisileyo kwe-ATP kunxulunyaniswa nenkqubo yokuguga.Ukongeza kumanqanaba okunyusa ama-neurotransmitters NGF kunye ne-BDNF, i-J-147 inokulawula oku.Ukongeza, i-J-147 inqanda i-monoamine oxidase B kunye ne-dopamine transporter.Ukukhuthaza ukukhula kwengqondo ngokunyusa amanqanaba e-nerve growth factor (NGF) kunye ne-brain-derived neurotrophic factor (BDNF).Okona kubaluleke kakhulu, i-J-147 inokukhuthaza ukukhula kweeseli zemithambo-luvo entsha, iphucule amandla okufunda kunye nenkumbulo yengqondo, kunye nokuphucula ukusebenza kwengqondo.
Uphawu
(1) Ubunyulu obuphakamileyo: I-J-147 inokufumana iimveliso ezicocekileyo ngokucokisa iinkqubo zokuvelisa.Ukucoceka okuphezulu kuthetha ukuba ngcono kwe-bioavailability kunye neempendulo ezimbalwa ezimbi.
(2) Ukhuseleko: I-J-147 ibonakaliswe ukuba ikhuselekile kumzimba womntu.
(3) Ukuzinza: I-J-147 inozinzo oluhle kwaye inokugcina umsebenzi wayo kunye nesiphumo phantsi kweemeko ezahlukeneyo kunye neemeko zokugcina.
(4) Kulula ukufunxa: I-J-147 inokuthatyathwa ngokukhawuleza ngumzimba womntu, ingena kwi-blood circulation ngamathumbu, kwaye isasazwe kwizicubu ezahlukeneyo kunye nezitho.
Usetyenziso
I-J-147 i-synthetic compound egama layo liphambili lesenzo libandakanya ukuphuculwa kwe-mitochondrial, ngaloo ndlela kuphuculwe ukuveliswa kwamandla kwinqanaba leselula.I-J-147 yenzelwe ukukhulisa amandla engqondo okuzilungisa nokuzikhusela kumonakalo onxulumene nobudala ngokuphucula ukusebenza kwe-mitochondrial.Ukongezelela, i-J-147 ibonisa iimpawu ezichasene ne-anti-inflammatory kunye ne-antioxidant, iqhubela phambili ukuphucula iziphumo zayo ze-neuroprotective.I-J-147 inokukhuthaza ukukhula kweeseli zemithambo-luvo entsha, iphucule ikhono lokufunda kwengqondo kunye nenkumbulo, kunye nokuphucula ukusebenza kwengqondo.
