Umenzi womgubo we-J-147 Inombolo ye-CAS: 1146963-51-0 Ubumsulwa obuyi-99.0% ubuncinci bezithako ezongezelelweyo
Iiparamitha zeMveliso
| Igama lemveliso | I-2,2,2-Trifluoroacetic acid 1-(2,4-DiMethylphenyl)-2-[(3-Methoxyphenyl)Methylene]hydrazide] |
| Elinye igama | J-147, J147 |
| Inombolo ye-CAS | 1146963-51-0 |
| Ifomula yemolekyuli | C18H17F3N2O2 |
| Ubunzima be-molecular | 350.33 |
| Ubunyulu | 99% |
| Inkangeleko | Umgubo omhlophe |
| Ukupakisha | 1kg ngebhegi nganye |
| Isicelo | ii-nootropics |
Intshayelelo yeMveliso
I-J-147 sisithinteli se-neuroprotective esinamandla kakhulu esisebenza ngomlomo esiphuma kwi-curcumin, isithako esisebenzayo kwi-turmeric. Ngokungafaniyo ne-curcumin, inqumla umqobo wegazi-ubuchopho ngempumelelo kakhulu. Phakathi kwazo, i-J-147 isebenza ngokubophelela kwi-ATP synthase. Ukuveliswa kakhulu kwe-ATP kunxulunyaniswa nenkqubo yokwaluphala. Ukongeza ekunyuseni amanqanaba e-neurotransmitters i-NGF kunye ne-BDNF, i-J-147 inokulawula oku. Ukongeza, i-J-147 ithintela i-monoamine oxidase B kunye ne-dopamine transporter. Ikhuthaza ukukhula kwengqondo ngokunyusa amanqanaba e-nerve growth factor (NGF) kunye ne-brain-derived neurotrophic factor (BDNF). Okubaluleke kakhulu, i-J-147 inokukhuthaza ukukhula kweeseli ze-nerve ezintsha, iphucule amandla okufunda kunye nenkumbulo yengqondo, kwaye iphucule ukusebenza kwengqondo.
Uphawu
(1) Ubunyulu obuphezulu: I-J-147 inokufumana iimveliso ezinyulu obuphezulu ngokusebenzisa iinkqubo zemveliso zokucoca. Ubunyulu obuphezulu buthetha ukufumaneka ngcono kwezinto eziphilayo kunye neempendulo ezimbalwa ezingalunganga.
(2) Ukhuseleko: I-J-147 ibonakalisiwe ukuba ikhuselekile emzimbeni womntu.
(3) Uzinzo: I-J-147 inozinzo oluhle kwaye ingayigcina intshukumo yayo phantsi kweemeko ezahlukeneyo kunye neemeko zokugcina.
(4) Kulula ukufunxa: I-J-147 inokufunxwa ngokukhawuleza ngumzimba womntu, ingene kwi-blood circulation ngamathumbu, ize isasazwe kwiithishu kunye namalungu ahlukeneyo.
Izicelo
I-J-147 yikhompawundi eyenziweyo enendlela yayo yokusebenza ephambili ebandakanya ukuphuculwa kwe-mitochondrial, ngaloo ndlela iphucula ukuveliswa kwamandla kwinqanaba leeseli. I-J-147 yenzelwe ukuphucula amandla engqondo okuzilungisa nokuzikhusela kumonakalo onxulumene nobudala ngokuphucula ukusebenza kwe-mitochondrial. Ukongeza, i-J-147 ibonisa iipropati ezibalulekileyo zokulwa nokuvuvukala kunye ne-antioxidant, iphucula ngakumbi iziphumo zayo zokukhusela imithambo-luvo. I-J-147 inokukhuthaza ukukhula kweeseli ezintsha zemithambo-luvo, iphucule amandla okufunda engqondo kunye nenkumbulo, kwaye iphucule ukusebenza kwengqondo.
