Umenzi womgubo weBeta-Nicotinamide Adenine Dinucleotide(NAD+) Inombolo yeCAS: 53-84-9 Ubumsulwa obuyi-98.5% ubuncinci bezithako ezongezelelweyo

Inkcazo emfutshane:

I-NAD+, okanye i-nicotinamide adenine dinucleotide, yi-coenzyme efumaneka kuzo zonke iiseli eziphilayo. Idlala indima ebalulekileyo kwi-metabolism yeseli, ngakumbi kwi-redox reactions, ezibandakanya ukudluliselwa kwee-electron phakathi kwee-molecules. I-NAD+ ibandakanyeka kwi-anabolic kunye ne-catabolic reactions, nto leyo eyenza ukuba ibe yinxalenye ebalulekileyo ye-metabolism yamandla.

Thumela i-imeyile kuthi

Iinkcukacha zeMveliso

Iithegi zeMveliso

Iiparamitha zeMveliso

Igama lemveliso	I-Nicotinamide Mononucleotide
Elinye igama	I-RIBOTIDE YE-NICOTINAMIDE; I-BETA-Nicotinamide Mononucleotide； I-Ribonucleotide yeNicotinaMide; I-β-Nicotinamide Mononucleotide ()
Inombolo ye-CAS	1094-61-7
Ifomula yemolekyuli	C11H15N2O8P
Ubunzima be-molecular	334.22
Ubunyulu	98.0%
Inkangeleko	Umgubo omhlophe
Ukupakisha	1kg/ibhegi 10kg/igubu
Isicelo	Ukulwa nokwaluphala

Intshayelelo yemveliso

I-Beta-Nicotinamide Adenine Dinucleotide (i-Beta-NAD+), eyaziwa ngokuba yi-Beta-NAD, yimolekyuli ebalulekileyo efumaneka kuzo zonke iiseli eziphilayo. Idlala indima ebalulekileyo kwiinkqubo ezahlukeneyo zebhayoloji, kubandakanya imetabolism yamandla kunye nokuhanjiswa kwemiqondiso yeeseli. I-Beta-Nicotinamide Adenine Dinucleotide yenziwe kwi-niacin (i-vitamin B3) kunye ne-ATP (i-adenosine triphosphate) ngothotho lweempendulo ze-enzyme. Ngexesha lokuphefumla kweseli, i-Beta-Nicotinamide Adenine Dinucleotide yi-coenzyme enceda ukudluliselwa kwee-electron ngexesha lokuqhekeka kweglucose kunye nezinye ii-biomolecules. Olu kudluliselwa kwee-electron lubalulekile ekuveliseni i-ATP, imali yamandla yeseli. Ngaphandle kwe-Beta-Nicotinamide Adenine Dinucleotide, iiseli azinakuvelisa amandla ngokufanelekileyo kwaye zenze imisebenzi yazo ebalulekileyo. Ukongeza kwindima yayo kwimetabolism yamandla, i-Beta-Nicotinamide Adenine Dinucleotide isebenza njengesiseko see-enzyme ezahlukeneyo ezibandakanyekayo ekunikezelweni kwemiqondiso kunye nokulawulwa kweeseli. Elinye iqela elaziwayo lee-enzymes ezisebenzisa i-Beta-Nicotinamide Adenine Dinucleotide zii-Sirtuins, ezibandakanyeka kwiinkqubo ezahlukeneyo zeseli, kubandakanya ukulungiswa kwe-DNA, ukubonakaliswa kwezakhi zofuzo, kunye nokwaluphala. Ezi enzymes zifuna i-Beta-Nicotinamide Adenine Dinucleotide njenge-cofactor ukuze zisebenzise umsebenzi wazo we-enzyme.

Uphawu

(1) Ubunyulu obuphezulu: I-NAD+ inokufumana iimveliso ezinyulu obuphezulu ngokusebenzisa iinkqubo zemveliso zokucoca. Ubunyulu obuphezulu buthetha ukufumaneka ngcono kwezinto eziphilayo kunye neempendulo ezimbalwa ezingalunganga.

(2) Ukhuseleko: Ukhuseleko oluphezulu, zimbalwa iziphumo ezibi.

(3) Uzinzo: I-NAD+ izinzile kakuhle kwaye inokugcina umsebenzi wayo kunye nesiphumo phantsi kweemeko ezahlukeneyo kunye neemeko zokugcina.

Izicelo

I-NAD+ yi-coenzyme edlala indima ebalulekileyo kwiinkqubo ezahlukeneyo zebhayoloji, kubandakanya imetabolism yamandla, ukulungiswa kwe-DNA, kunye nokubonisa iiseli. I-NAD+ ikwabandakanyeka kwezinye iinkqubo zeseli ezifana nokulungiswa kwe-DNA, ukubonakaliswa kwezakhi zofuzo, kunye nokubonisa i-calcium. Kubalulekile ekugcineni ukwaluphala okunempilo, njengoko amanqanaba e-NAD+ ehla ngokukhula, okukhokelela ekunciphiseni imetabolism yeeseli kunye nokwanda komonakalo weeseli. Amanqanaba e-NAD+ ayancipha ngokukhula, kwaye oku kwehla kunxulunyaniswa nezifo ezinxulumene nokuguga. Ukongezwa kwezinto ezisandula ukuguga ze-NAD+ kubonakalisiwe ukuba kunyusa amanqanaba e-NAD+ kwaye kunemiphumo emihle yokwaluphala.