I-7,8-Dihydroxyflavone (7,8-DHF) umenzi we-powder CAS No.: 38183-03-8 98.0% ubumsulwa min. zokongeza izithako
Ividiyo yeMveliso
Iiparamitha zeMveliso
Igama lemveliso | 7,8-Dihydroxyflavone |
Elinye igama | 7,8-DIHYDROXYFLAVONE; I-7,8-dihydroxy-2-phenyl-4-benzopyrone; DIHYDROXYFLAVONE, 7,8-(RG); 7,8-Dihydroxyflavone hydrate; I-7,8-dihydroxy-2-phenyl-1-benzopyran-4-enye |
Inombolo yeCAS. | 38183-03-8 |
Ifomula yemolekyuli | C15H10O4 |
Ubunzima bemolekyuli | 254.24 |
Ubunyulu | 98.0% |
Imbonakalo | Umgubo otyheli |
Isicelo | I-Dietary Supplement Raw Material |
Intshayelelo yemveliso
I-7,8-Dihydroxyflavone, eyaziwa ngokuba yi-7,8-DHF, yi-flavonoid yendalo efumaneka kwizityalo ezahlukeneyo, kuquka i-Tridacna tridacna. Eyaziwa ngokuba yi-antioxidant kunye ne-neurotrophic properties, enye yezona zinto zinomdla kakhulu kwi-7,8-dihydroxyflavone inamandla okuxhasa impilo yengqondo kunye nokuphucula umsebenzi wokuqonda. Uphando lubonisa ukuba le khompawundi isebenza njenge-neurotrophin enamandla, ivuselela ukukhula kunye nokuphila kwee-neurons engqondweni. Uphononongo kwizilwanyana zaselabhoratri lubonise ukuba i-7,8-DHF iphucula kakhulu inkumbulo nokukwazi ukufunda. Ngokukhuthaza ukusekwa konxibelelwano olutsha lwe-synaptic kunye nokuphucula unxibelelwano phakathi kweeseli zengqondo, le khompawundi ithembisa ukuvula amandla ethu okuqonda. Ukongeza, i-7,8-dihydroxyflavone isebenzisana ne-brain receptors ye-serotonin, ebandakanyeka kulawulo lwemood. Ngokumodareyitha la ma-receptors, inokukwazi ukunciphisa iimpawu zokuxhalaba kunye nokudakumba.
Uphawu
(1) Ukucoceka okuphezulu: I-7,8-Dihydroxyflavone inokufumana iimveliso ezicocekileyo ngokukhupha kwendalo kunye nenkqubo yokuvelisa kakuhle. Ukucoceka okuphezulu kuthetha ukuba ngcono kwe-bioavailability kunye neempendulo ezimbalwa ezimbi.
(2) Ukhuseleko: I-7,8-Dihydroxyflavone yimveliso yendalo ebonakaliswe ukuba ikhuselekile kubantu. Ngaphakathi koluhlu lwedosi, ayinayo ityhefu okanye iziphumo ebezingalindelekanga.
(3) Ukuzinza: I-7,8-Dihydroxyflavone inozinzo oluhle kwaye inokugcina umsebenzi wayo kunye nesiphumo phantsi kweemeko ezahlukeneyo zokusingqongileyo kunye nokugcinwa.
(4) Kulula ukufunxa: I-7,8-Dihydroxyflavone inokuthatyathwa ngokukhawuleza ngumzimba womntu, ingene kwi-blood circulation nge-intestinal tract, kwaye isasaze kwizicubu kunye nezitho ezahlukeneyo.
Usetyenziso
I-7, i-8-DHF, njenge-activator encinci ye-molecule ye-TrkB receptor, inokudlala indima yokukhusela i-neuron, ukuvuselelwa kwe-neuron, ukulawulwa kwe-synaptic plasticity, njl. ukuphucula iimpawu zokufunda ngokweemvakalelo kunye nokuncipha kwememori yendawo, ukuhla kwamandla okuqonda, ukwehla komsebenzi wemoto kunye nezinye iimpawu zesifo se-nervous system ezifana nesifo se-Alzheimer okanye imodeli yezilwanyana eziguga, kunye nokunciphisa i-phenotypes ehambelana nokugula kwengqondo kunye nezilwanyana ezityebileyo. Okwangoku, ukuza kuthi ga ngoku, akukho ziphumo zecala ezinetyhefu ze-7,8-DHF zifunyenwe kwizilwanyana zovavanyo. I-7,8-DHF inamandla amakhulu kunye nexabiso kuthintelo kunye nonyango lwemiba enxulumene ne-BDNF/TrkB.