1,4-DihydronicotinaMide Riboside powder umenzi CAS No.: 19132-12-8 98% ubumsulwa min. zokongeza izithako
Iiparamitha zeMveliso
| Igama lemveliso | 1,4-DihydronicotinaMide Riboside |
| Elinye igama | I-1,4-DIHYDRONICOTINAMIDE RIBOSIDE1-[(3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,4-dihydropyridine-3-carboxamideSCHEMBL188493711-[(3R,4S,5R)-3,4-DIHYDROXY-5-(HYDROXYMETHYL)OXOLAN-2-YL]-4H-PYRIDINE-3-CARBOXAMIDE |
| Inombolo yeCAS. | 19132-12-8 |
| Ifomula yemolekyuli | I-C11H16N2O5 |
| Ubunzima bemolekyuli | 256.26 |
| Ubunyulu | 98% |
| Imbonakalo | Umgubo omhlophe |
| Ukupakisha | 1kg/ibhegi;25kg/igubu |
| Isicelo | Izongezo zokutya izinto ezikrwada |
Intshayelelo yemveliso
I-1,4-dihydronicotinamide riboside, eyaziwa ngokuba yi-NRH.Uhlobo oluncitshisiweyo lwe-NRH luyi-precursor ye-NAD + enamandla enceda ukugcwalisa amanqanaba ayo kwiseli.
Okokuqala nokuphambili, kubalulekile ukuqonda indima ye-NAD + emzimbeni. I-NAD + yi-coenzyme ebandakanyeka kwiinkqubo ezininzi zeselula, kubandakanya amandla e-metabolism, ukulungiswa kwe-DNA, kunye nokubonakaliswa kofuzo. Njengoko sikhula, amanqanaba ethu e-NAD + ehla, ethe yabandakanyeka kwinkqubo yokuguga kunye nezifo ezinxulumene neminyaka. Oku kukhokelele kumdla okhulayo wokuchonga iimolekyuli ezinokonyusa amanqanaba e-NAD + emzimbeni, kwaye i-1,4-dihydronicotinamide riboside yenye molekyuli.
I-1,4-dihydronicotinamide riboside yi-precursor ye-NAD+ enamandla, kwaye uphando lubonise ukuba inokunyusa ngokufanelekileyo amanqanaba e-NAD + kwiiseli. Oku kukhokelele kuqikelelo lokuba i-1,4-dihydronicotinamide riboside supplementation inokuba namandla onyango kuluhlu olubanzi lweemeko zempilo, kubandakanya ukuphazamiseka kwemetabolism, izifo ze-neurodeergenerative, kunye nokwehla okunxulumene nokwaluphala.
Ngapha koko, kukho ubungqina bokucebisa ukuba i-1,4-dihydronicotinamide riboside inokusebenza ngakumbi kuneamolekyuli yomzali wayo, i-nicotinamide riboside, ekunyuseni amanqanaba e-NAD +. Oku kungenxa yokuba i-1,4-dihydronicotinamide riboside sisinciphisi esinamandla ngakumbi, okuthetha ukuba kungcono ukunikela ngee-electron kwi-NAD+ synthesis pathway. Ngenxa yoko, inamandla okuvelisa ngokufanelekileyo i-NAD + yeselula.
Ukongeza kwindima yayo kwi-NAD+ biosynthesis, i-1,4-dihydronicotinamide riboside nayo ineempawu ze-antioxidant. Uxinzelelo lwe-oxidative, olubangelwa kukungalingani phakathi kweeradicals zasimahla kunye ne-antioxidants emzimbeni, luchaphazeleka kwizifo ezininzi, kubandakanya umhlaza, isifo sentliziyo, kunye nokuphazamiseka kwe-neurodeergenerative. Ngokukhupha ii-radicals zasimahla kunye nokunciphisa umonakalo owenziwe nge-oxidative, i-1,4-dihydronicotinamide riboside inokubonelela ngeenzuzo ezongezelelweyo zempilo ngaphaya kwendima yayo njenge-NAD+ isandulela.
Uphawu
(1) Ukucoceka okuphezulu: I-1,4-dihydronicotinamide riboside inokufumana iimveliso ezicocekileyo ngokucokisekileyo ngeenkqubo zokuvelisa. Ukucoceka okuphezulu kuthetha ukuba ngcono kwe-bioavailability kunye neempendulo ezimbalwa ezimbi.
(2) Ukhuseleko: I-1,4-dihydronicotinamide riboside yimveliso yendalo ebonakaliswe ukuba ikhuselekile kumzimba womntu.
(3) Ukuzinza: I-1,4-dihydronicotinamide riboside inozinzo oluhle kwaye inokugcina umsebenzi wayo kunye nesiphumo phantsi kweemeko ezahlukeneyo kunye neemeko zokugcina.
Usetyenziso
I-1,4-Dihydronicotinamide yindlela encitshisiweyo ye-nicotinamide riboside. Inokubakho kuzo zombini iifom ezine-oxidized kunye nezincitshisiweyo kwaye isandulela kwi-NAD esanda kufunyanwa (i-nicotinamide adenine dinucleotide), ekhoyo njenge-supplement, kunye ne-NRH ibe yi-precursor ye-NAD+ enamandla ngakumbi kwaye ekhawulezayo kune-NR.
