Nefiracetam powder umenzi CAS No.: 77191-36-7 99% ubumsulwa min. zokongeza izithako
Ividiyo yeMveliso
Iiparamitha zeMveliso
| Igama lemveliso | Nefiracetam |
| Elinye igama | n-(2,6-dimethylphenyl) -2-oxo-1-pyrrolidineacetamide;NEFIRACETAM; I-2-oxo-1-pyrrolidinylaceticacid, i-2,6-dimethylanilide; I-dm9384; n-(2,6-dimethylphenyl) -2-oxo-1-pyrrolidineacetamid;DM-9384,(2-(2-Oxopyrrolidin-1-yl)-N-(2,6-dimethylphenyl)-acetamide); I-DMMPA |
| Inombolo yeCAS. | 77191-36-7 |
| Ifomula yemolekyuli | I-C14H18N2O2 |
| Ubunzima bemolekyuli | 246.3 |
| Ubunyulu | 99.0% |
| Imbonakalo | Umgubo omhlophe |
| Ukupakisha | 25 kg / umphanda |
| Isicelo | nootropic |
Intshayelelo yemveliso
I-Nefiracetam yeyosapho lwepiracetam, iklasi yeziyobisi ezaziwa ngeempawu zazo zokuphucula ingqondo. I-Nefiracetam yaqala ukwenziwa kwi-1980 yokuqala kwaye yatsala ingqalelo ngokukhawuleza ngenxa yendlela ekhethekileyo yokusebenza kunye nezicelo zonyango ezinokubakho. Le khompawundi ye-racemic kucingelwa ukuba ichaphazela i-neurotransmitters kunye ne-receptors kwingqondo, ekugqibeleni ikhuthaza ukuphuculwa kwezakhono zokuqonda. I-Nefiracetam ngokuyinhloko ichaphazela amanqanaba engqondo ye-acetylcholine, i-neurotransmitter ephambili ejongene nememori, ukufunda kunye nokusebenza kwengqondo. Ngokumodareyitha i-acetylcholine receptors, i-nefiracetam ikhuthaza ukwanda konxibelelwano phakathi kwe-neurons, ngaloo ndlela iphucula iplastiki ye-synaptic kunye nokuphucula ukugcinwa kwememori. Ukongezelela, i-nefiracetam isebenzisana ne-gamma-aminobutyric acid (GABA) i-receptors yokunceda ukulinganisela i-neurotransmitter milieu. Ngokuchaphazela ngokufanelekileyo i-neurotransmitters ye-excitatory kunye ne-inhibitory, i-nefiracetam inceda ukugcina ukusebenza kwengqondo efanelekileyo, ngaloo ndlela iphucula ukugxila, ingqalelo, kunye nokusebenza kwengqondo jikelele.
Uphawu
(1) Ukucoceka okuphezulu: I-Nefiracetam inokufumana iimveliso ezicocekileyo ngokucokisa iinkqubo zokuvelisa. Ukucoceka okuphezulu kuthetha ukuba ngcono kwe-bioavailability kunye neempendulo ezimbalwa ezimbi.
(2) Ukhuseleko: Ukhuseleko oluphezulu, zimbalwa izenzo ezibi.
(3) Ukuzinza: I-Nefiracetam inozinzo oluhle kwaye inokugcina umsebenzi wayo kunye nesiphumo phantsi kweemeko ezahlukeneyo kunye neemeko zokugcina.
Usetyenziso
I-Nefiracetam yi-hydrophobic derivative ye-piracetam, ngokuqhelekileyo ithathwa njengento ejongene nokufunyanwa kweziteshi ze-calcium emzimbeni kunye nokudluliselwa ngokuthe ngqo kwezinto ezibonisa i-excitatory njenge-agonist inxalenye ye-calcium ion channels. Indawo yokubopha iGlycine ye-NDMA receptor. Ngempembelelo yayo kwi-cortex ye-cerebral, i-nefiracetam inokuphucula amandla okuqonda kunye nokuthintela ukufunda kunye nokukhubazeka kwememori. Ayinayo i-muscarinic receptor agonist okanye iipropathi ezichasayo, kwaye ayivimbeli umsebenzi we-acetylcholinease. Ngoko ke, iziphumo zayo zokulwa ne-amnestic kunye nokuphucula imemori zifezekiswa ngokuphucula ukukhululwa kwe-acetylcholine kwi-cortex ye-cerebral.
