I-Beta-Nicotinamide Adenine Dinucleotide (NAD +) umenzi we-powder CAS No.: 53-84-9 98.5% ubumsulwa min. zokongeza izithako
Iiparamitha zeMveliso
Igama lemveliso | Nicotinamide Mononucleotide |
Elinye igama | I-NICOTINAMIDE RIBOTIDE; BETA-Nicotinamide Mononucleotide; NicotinaMide Ribonucleotide; I-β-Nicotinamide Mononucleotide () |
Inombolo yeCAS. | 1094-61-7 |
Ifomula yemolekyuli | I-C11H15N2O8P |
Ubunzima bemolekyuli | 334.22 |
Ubunyulu | 98.0% |
Imbonakalo | Umgubo omhlophe |
Ukupakisha | 1kg/ibhegi 10kg/igubu |
Isicelo | Ukuchasa ukuguga |
Intshayelelo yemveliso
I-Beta-Nicotinamide Adenine Dinucleotide (i-Beta-NAD +), eyaziwa ngokuba yi-Beta-NAD, i-molecule ebalulekileyo efumaneka kuzo zonke iiseli eziphilayo. Idlala indima ebalulekileyo kwiinkqubo ezahlukeneyo zebhayoloji, kubandakanywa amandla e-metabolism kunye nokubonakaliswa kweeseli. I-Beta-Nicotinamide Adenine Dinucleotide yenziwe kwi-niacin (i-vitamin B3) kunye ne-ATP (i-adenosine triphosphate) ngoluhlu lwee-enzymatic reactions. Ngexesha lokuphefumula kweselula, i-Beta-Nicotinamide Adenine Dinucleotide yi-coenzyme eyenza ukuhanjiswa kwe-electron ngexesha lokuphuka kwe-glucose kunye nezinye i-biomolecules. Olu dluliselo lwe-electron lubalulekile ekuveliseni i-ATP, imali yamandla ehlabathi jikelele yeseli. Ngaphandle kweBeta-Nicotinamide Adenine Dinucleotide, iiseli azikwazi ukuvelisa amandla ngokufanelekileyo kwaye zenze imisebenzi yazo ebalulekileyo. Ukongeza kwindima yayo kwi-metabolism yamandla, i-Beta-Nicotinamide Adenine Dinucleotide isebenza njenge-substrate yee-enzymes ezahlukeneyo ezibandakanyekayo ekubonakalisweni kweeseli kunye nokulawula. Iqela elinye elaziwayo le-enzymes elisebenzisa iBeta-Nicotinamide Adenine Dinucleotide ziiSirtuins, ezibandakanyeka kwiinkqubo ezahlukeneyo zeseli, kubandakanya ukulungiswa kweDNA, ukubonakaliswa kofuzo, kunye nokuguga. Ezi enzymes zifuna i-Beta-Nicotinamide Adenine Dinucleotide njenge-cofactor yokwenza umsebenzi wabo we-enzymatic.
Uphawu
(1) Ukucoceka okuphezulu: I-NAD + inokufumana iimveliso ezicocekileyo ngokucokisa iinkqubo zokuvelisa. Ukucoceka okuphezulu kuthetha ukuba ngcono kwe-bioavailability kunye neempendulo ezimbalwa ezimbi.
(2) Ukhuseleko: Ukhuseleko oluphezulu, zimbalwa izenzo ezibi.
(3) Ukuzinza: I-NAD + inozinzo oluhle kwaye inokugcina umsebenzi wayo kunye nesiphumo phantsi kweemeko ezahlukeneyo kunye neemeko zokugcina.
Usetyenziso
I-NAD + yi-coenzyme edlala indima ebalulekileyo kwiinkqubo ezahlukeneyo zebhayoloji, kubandakanya amandla e-metabolism, ukulungiswa kwe-DNA, kunye nokubonakaliswa kweeseli. I-NAD + ikwabandakanyeka kwezinye iinkqubo zeselula ezifana nokulungiswa kwe-DNA, ukubonakaliswa kofuzo, kunye nokubonakaliswa kwe-calcium. Kubalulekile ukugcina ukwaluphala okunempilo, njengoko amanqanaba e-NAD + ehla ngeminyaka, ekhokelela ekunciphiseni kwemetabolism yeeseli kunye nokwanda komonakalo weeseli. Amanqanaba e-NAD + ehla ngokukhula, kwaye oku kuncipha kunxulunyaniswa nezifo ezinxulumene neminyaka. Ukongezwa nge-NAD+ precursors kubonisiwe ukonyusa amanqanaba e-NAD + kwaye kuneziphumo zokuguga ezisempilweni.