I-Lemairamin (WGX-50) umenzi we-powder CAS No.: 29946-61-0 98.0% ubumsulwa min. zokongeza izithako
Ividiyo yeMveliso
Iiparamitha zeMveliso
| Igama lemveliso | Lemairamin |
| Elinye igama | I-2-Propenamide, N-[2-(3,4-dimethoxyphenyl)ethyl]-3-phenyl-, (2E)-; ILemairamin (WGX-50) |
| Inombolo yeCAS. | 29946-61-0 |
| Ifomula yemolekyuli | C19H21NO3 |
| Ubunzima bemolekyuli | 311.37 |
| Ubunyulu | 98.0% |
| Imbonakalo | Umgubo omhlophe ukuya kumhlophe |
| Isicelo | I-Dietary Supplement Raw Material |
Intshayelelo yemveliso
I-Lemairamin okanye i-Wgx50 yinkompawundi yendalo ekhutshwe kwipepile yetshilisi ebonise iziphumo ezithembisayo ekuthinteleni isifo se-Alzheimer. Uphononongo lufumene ukuba lunokuthintela i-Aβ-induced neuronal apoptosis, ukunciphisa i-neuronal calcium toxicity, kunye nokunciphisa ukuqokelelwa kwe-Aβ oligomers kwi-cortex ye-cerebral. Ukongeza, i-wgx50 ibonakaliswe ukuphucula ukusebenza kwengqondo kwiimpuku. Uphando lucebisa ukuba i-wgx50 inamandla okuthintela ukudityaniswa kweeprotheyini phakathi kweeamyloid. Lilonke, i-wgx50 inamandla okuthintela isifo se-Alzheimer kwaye inokubonelela ngeendlela ezintsha zophuhliso lwamachiza ajolise kwi-Aβ oligomers. Ukongezelela, i-WGX-50 ibonisa umsebenzi omkhulu wokuchasana nokuvuvukala, okwenza kube ngumviwa othembisayo wonyango lwezifo ezivuthayo. I-WGX-50 ifunyenwe ibe nemiphumo ebalulekileyo eluswini, njengokunciphisa imibimbi kunye nokuphucula ukuqina kwesikhumba. Ukongeza kwiikhompawundi zendalo ezikhutshwe kwisityalo i-Zanthoxylum bungeanum, ngoku kukho iikhompawundi ezininzi zokwenziwa ezisetyenziswa kwizicelo ezahlukeneyo kwaye zifaneleke ngakumbi kwimarike.
Uphawu
(1) Ukucoceka okuphezulu: I-Lemairamin inokufumana iimveliso ezicocekileyo ngokukhupha kwendalo kunye neenkqubo zokuvelisa. Ukucoceka okuphezulu kuthetha ukuba ngcono kwe-bioavailability kunye neempendulo ezimbalwa ezimbi.
(2) Ukhuseleko: Ukhuseleko oluphezulu, ukusabela okungathandekiyo okumbalwa, akukho zithintelo ezicacileyo ezicacileyo nokuba zisetyenziswe ixesha elide.
(3) Ukuzinza: I-Lemairamin inozinzo oluhle kwaye inokugcina umsebenzi wayo kunye nesiphumo phantsi kweemeko ezahlukeneyo kunye neemeko zokugcina.
(4) Kulula ukufunxa: ILemairamin inokufunxwa ngokukhawuleza ngumzimba womntu kwaye isasazwe kwizicubu kunye namalungu ahlukeneyo.
Usetyenziso
ILemairamin yinkompawundi ye-amide ekhutshwe kwixolo lesityalo i-Zanthoxylum bungeanum. Okwangoku isetyenziswe njengesongezelelo sokutya, iphinda isebenze njenge-agonist ye-alpha7 nicotinic acetylcholine receptor (α7nAChR), eyanciphisa i-neuroinflammation kwi-Alzheimer's disease, kwaye yenziwe ngokupheleleyo. i-apoptosis, ukunciphisa i-neuronal calcium toxicity, ukunciphisa ukuqokelelwa kwe-Aβ oligomers kwi-cortex ye-cerebral, kunye nokuphucula ukusebenza kwengqondo kwiimpuku.
