YDL223C (HBT1) umenzi we-powder CAS No.: 489408-02-8 99% ubumsulwa min. zokongeza izithako

I-HBT1 ibophelela kwi-domain ye-ligand-binding ye-α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPA-R) ngendlela exhomekeke kwi-glutamate. Oku kuthetha ukuba i-HBT1 yimolekyuli enokuthi ibophe kuphela kwindawo ethile kwiprotheni ye-AMPA-R xa i-glutamate ikhona, kwaye oku kubopha kunceda ukulawula umsebenzi weprotheni. Ama-receptors e-AMPA abonakaliswa kuyo yonke inkqubo ye-nervous central kwaye adlale indima ebalulekileyo kunxibelelwano lwe-neuronal, ukusetyenzwa kweenzwa, ukufunda, imemori, kunye ne-synaptic plasticity. I-AMPA i-receptors inegalelo elikhulu kwi-neurotransmission evuselelayo, i-mediate ngokukhawuleza, ngokukhawuleza yenza ukuba i-synapses ikhuphe ngokukhawuleza, kwaye ibandakanyeka kwiimpendulo zakwangoko kwi-glutamate kwimimandla ye-synaptic. Ama-receptors e-AMPA ahlala edityaniswa kunye ne-NMDA receptors kwii-synapses, kwaye kunye zikhuthaza iinkqubo zeplastiki ze-synaptic ezibandakanyeka ekufundeni, imemori, i-excitotoxicity, kunye ne-neuroprotection. I-brain-derived neurotrophic factor (BDNF) i-neurotrophic factor edlala indima ebalulekileyo ekugcinweni nasekukhuliseni i-neurons kwaye ineempembelelo ezinamandla kunye neninzi ekwandeni, ukwahlula, ukusinda kunye nokufa kweeseli ze-neuronal kunye ne-non-neuronal. , imodyuli ye-neurotransmitter enegalelo kwi-neuronal plasticity ekufundeni nakwimemori. Ngoko ke, kubalulekile kwimpilo kunye nokuphila kakuhle kwenkqubo ye-nervous.