I-Palmitoylethanolamide (PEA Granule) umenzi we-powder CAS No.: 544-31-0 97% ubumsulwa min. zokongeza izithako
Iiparamitha zeMveliso
| Igama lemveliso | I-PEA |
| Elinye igama | N-(2-HYDROXYETHYL)HEXADECANAMIDE; N-HEXADECANOYLETHANOLAMINE; I-PEAPALMIDROL; I-PALMITYLETHANOLAMIDE; PALMITOYLETHANOLAMIDE |
| Inombolo yeCAS. | 544-31-0 |
| Ifomula yemolekyuli | C18H37NO2 |
| Ubunzima bemolekyuli | 299.49 |
| Ubunyulu | 97.0% |
| Imbonakalo | Umgubo wegranulated omhlophe |
| Ukupakisha | 1kg/ibhegi,25Kg/igubu |
| Isicelo | Imathiriyeli ekrwada yeemveliso zokhathalelo lwempilo |
Intshayelelo yemveliso
I-Palmitoylethanolamide yimolekyuli yesithunywa se-lipid esafunyanwa okokuqala ngasekupheleni kweminyaka yoo-1950. Kukwiklasi yeekhompawundi ezibizwa ngokuba yi-endocannabinoids, zizinto zendalo ezisebenzisana nenkqubo ye-endocannabinoid yomzimba. Ngokungafaniyo nezinye i-cannabinoids ezifana ne-THC efunyenwe kwisityalo se-cannabis, i-PEA ayinayo ingqondo kwaye ayivelisi nayiphi na imiphumo yokuguqula ingqondo. Inkqubo ye-endocannabinoid (ECS) yinethiwekhi eyinkimbinkimbi ye-receptors kunye ne-endocannabinoids efunyenwe kuwo wonke umzimba. Idlala indima ebalulekileyo ekulawuleni iinkqubo ezahlukeneyo ze-physiological, kubandakanywa ukuqonda intlungu, ukuvuvukala, kunye nomoya. I-PEA isebenza njenge-endogenous ligand ye-receptor ethile ngaphakathi kwe-ECS ebizwa ngokuba yi-peroxisome proliferator-activated receptor-α (PPAR-α). Ngokusebenzisa le receptor, i-PEA yenza i-anti-inflammatory and analgesic effects. Uphononongo lubonisa ukuba i-Palmitoylethanolamide inokunceda ukulawula intlungu engapheliyo, kuquka i-neuropathic kunye nentlungu evuthayo. Isebenza ngokunciphisa ukukhululwa kwezinto eziphazamisayo kunye nokulawula ukusebenza kweeseli ze-immune ezibandakanyekayo kwimpendulo yokuvuvukala. Izilingo ezininzi zeklinikhi zibonise ukusebenza kwe-PEA ekunciphiseni ubunzima beentlungu kunye nokuphucula umgangatho wobomi kwizigulane ezineemeko ezahlukeneyo zentlungu engapheliyo.
Uphawu
(1) Ukucoceka okuphezulu: I-PEA inokufumana iimveliso ezicocekileyo ngokucokisa iinkqubo zokuvelisa. Ukucoceka okuphezulu kuthetha ukuba ngcono kwe-bioavailability kunye neempendulo ezimbalwa ezimbi.
(2) Ukhuseleko: Ukhuseleko oluphezulu, zimbalwa izenzo ezibi.
(3) Ukuzinza: I-PEA inozinzo oluhle kwaye inokugcina umsebenzi wayo kunye nesiphumo phantsi kweemeko ezahlukeneyo kunye neemeko zokugcina.
Usetyenziso
Isetyenziswe njengesongezelelo sokutya, i-Palmitoylethanolamide yi-amide ye-fatty acid amide eyenzeka ngokwemvelo eyenza i-anti-inflammatory, analgesic, kunye ne-neuroprotective effects ngokusebenzisa i-modulation ye-endocannabinoid system. Iinzuzo zayo ezinokuthi zilawule iintlungu ezingapheliyo kunye nezinye iimeko zempilo zenza kube yinto enomdla kubantu abafuna ezinye iindlela zendalo. Ukongeza, i-PEA ikwayi-organic synthesis ephakathi kunye ne-pharmaceutical intermediate, enokuthi isetyenziswe kuphando lwebhubhoratri kunye neenkqubo zophuhliso kunye nophando lweziyobisi zemichiza kunye neenkqubo zophuhliso.
