I-NAD + (i-Beta-Nicotinamide Adenine Dinucleotide) yi-coenzyme efumaneka kuzo zonke iiseli eziphilayo kwaye iyimfuneko kwiinkqubo ezahlukeneyo zezinto eziphilayo, kuquka ukuveliswa kwamandla kunye nokulungiswa kwe-DNA. Njengoko sikhula, amanqanaba ethu e-NAD + ehla, ekhokelela kuluhlu lweengxaki zempilo. Ukulwa le ngxaki, abantu abaninzi baphendukela kwi-NAD + izongezo kwifomu yomgubo. Nangona kunjalo, ngokhetho oluninzi phaya, ukufumanisa ukuba yeyiphi i-NAD + powder eyona ilungileyo kunokuba ngumngeni. Ukukhetha eyona powder NAD + ifuna ukuqwalaselwa ngononophelo ubunyulu, i-bioavailability, idosi, ukucaca, kunye nengxelo yabathengi. Ngokubeka phambili ezi zinto, unokwenza isigqibo esinolwazi kwaye ukhethe umgangatho ophezulu we-NAD + powder oxhasa impilo yakho kunye nokuphila kakuhle.
I-NAD yenzeka ngokwemvelo kwiiseli zethu,ngokuyinhloko kwi-cytoplasm kunye ne-mitochondria, nangona kunjalo, amanqanaba endalo e-NAD ayancipha njengoko sikhula (rhoqo kwiminyaka eyi-20, enyanisweni), ebangela iziphumo eziqhelekileyo zokuguga, Njengokuncipha kwamanqanaba amandla kunye nokwanda kwentlungu kunye nobuhlungu. Ngaphezu koko, ukwehla okunxulumene nokwaluphala kwi-NAD kunxulunyaniswa nezinye izifo ezinxulumene nobudala, njengomhlaza, ukuncipha kwengqondo, kunye nobuthathaka.
I-NAD + ayisiyohormone, yicoenzyme. I-NAD + inokuphucula amandla e-DNA ukuzilungisa, ukwandisa ixesha lokuphila ngokuguqula ukwehla kwe-mitochondria, kunye nokukhusela i-DNA kunye nomonakalo we-mitochondrial. Kwaye inokuphucula uzinzo lwechromosome. I-NAD + ikwabizwa ngokuba "yimolekyuli yommangaliso" ebuyisela kwaye igcine impilo yeeseli. Kwizifundo zezilwanyana, kuye kwaqinisekiswa ukuba kunamandla anamandla okunyanga izifo ezahlukeneyo ezifana nesifo senhliziyo, isifo seswekile, isifo se-Alzheimer kunye nokukhuluphala.
I-NAD + ithatha inxaxheba kwiintlobo ezahlukeneyo ze-biochemical reactions ngaphakathi kweeseli, ezifana ne-glycolysis, i-fatty acid oxidation, i-tricarboxylic acid cycle, ikhonkco lokuphefumla, njl. Ezinye iimolekyuli, ezifana ne-NADH kunye ne-FAD, ukugcina ibhalansi ye-redox ye-intracellular. I-NAD + idlala indima ebalulekileyo kwimveliso yamandla eselula, ukhuseleko lweradical yasimahla, ukulungiswa kweDNA, kunye nomqondiso.
Ukongeza, i-NAD + ikwanxibelelene ngokusondeleyo nokuguga, kwaye amanqanaba ayo ehla ngokuhamba kweminyaka. Ke ngoko, ukugcina amanqanaba e-NAD + kudlala indima ebalulekileyo ekubambezeleni ukwaluphala, ukomeleza amandla, ukukhuthaza ukulungiswa kweeseli, ukuphucula ukusebenza kwengqondo, kunye nokulawula imetabolism.
Ngokucacileyo, ukwaluphala kukhatshwa kukwehla okuqhubelekayo kwezicubu kunye namanqanaba eselula e-NAD + kwiintlobo ngeentlobo zezinto eziphilayo, kubandakanya iimpuku kunye nabantu.
Ke ngoko, ukuzalisa kwangexesha umxholo we-NAD + emzimbeni kunokulibazisa ukwaluphala kwaye kuqinisekise impilo. Ukuba ufuna iminyaka ukuba ibe linani nje, yongeza i-NAD + kwangoko kangangoko ukuze ubonakale umncinci ukusuka ngaphakathi ngaphandle.
Amanqanaba e-NAD + ehla ngobudala, ikakhulu ngenxa yokuba izinga lemveliso alikwazi ukuhambisana nezinga lokusetyenziswa kwayo.
Inani elikhulu lophononongo lubonise ukuba ukwehla kwamanqanaba e-NAD + kunxulumene nezifo ezininzi ezinxulumene nokwaluphala, kubandakanya ukwehla kwengqondo, ukudumba, umhlaza, izifo ze-metabolic, i-sarcopenia, izifo ze-neurodeergenerative, njl.
Kungenxa yoko le nto sifuna izongezo zeNAD +. Njengohlobo lwethu lwe-collagen ye-3, ihlala ilahleka.
I-NAD + inokuxhathisa ukuguga. Nguwuphi umgaqo osekelwe kuyo?
i-nad+ yenza i-parp1 i-enzayimi yokulungisa imfuza
Inceda ukulungiswa kwe-DNA Enye yezinto ezibangela ukwaluphala kukonakala kweDNA. Iinwele zakho ezimhlophe, i-ovarian kunye nezinye izitho ziyancipha, zonke zinxulumene nomonakalo weDNA. Ukuhlala kude kube sebusuku kwaye ucinezelekile kuya kuwenza mandundu umonakalo weDNA.
Uphononongo lufumene ukuba i-NAD + inceda ukwenza i-PARP1 gene (esebenza njengomphenduli wokuqala wokubona umonakalo we-DNA kwaye emva koko ikhuthaze ukhetho lweendlela zokulungisa. I-PARP1 ikhokelela ekudakaleni kwesakhiwo se-chromatin ngokusebenzisa i-ADP ribosylation ye-histones, kwaye ibandakanyeka kwi-DNA eyahlukeneyo. ukulungisa Imiba iyasebenzisana kwaye iguqule, ngaloo ndlela iphucula ukulungiswa kakuhle), ngaloo ndlela ilungisa umonakalo we-DNA kunye nokukhuthaza ukuqhutyelwa kweenguqu ze-metabolic.
Isishwankathelo, i-NAD + inokuchaphazela ngokuthe ngqo nangokungathanga ngqo imisebenzi emininzi ephambili yeselula, kubandakanya iindlela zemetabolism, ukulungiswa kweDNA, ukulungiswa kwakhona kwechromatin, iseli yeselula, ukusebenza kweeseli zomzimba, njl. njl., ngaloo ndlela icothisa inkqubo yokuguga komntu.
NAD+ sisishunqulelo sesiNgesi sikaNicotinamide adenine dinucleotide. Igama layo elipheleleyo ngesiTshayina yi-nicotinamide adenine dinucleotide, okanye iCoenzyme I ngokufutshane. Njenge-coenzyme ehambisa i-hydrogen ions, i-NAD + idlala indima kwiinkalo ezininzi ze-metabolism yabantu, kuquka i-glycolysis, i-Gluconeogenesis, i-tricarboxylic acid cycle, njl njl. Ezinye izifundo zibonise ukuba ukuchithwa kwe-NAD + kuhambelana nobudala, kunye neendlela ze-physiological mediated. nge-NAD + inxulumene nokuguga, izifo ze-metabolic, i-neuropathy kunye nomhlaza, kubandakanywa nokulawula i-homeostasis ye-cell, i-sirtuins eyaziwa ngokuba yi-"longevity genes", ukulungisa i-DNA, iiprotheni zentsapho ze-PARPs ezinxulumene ne-necroptosis kunye ne-CD38 encedisa ukubonakaliswa kwe-calcium.
Ukuchasa ukuguga
Ukwaluphala kubhekisa kwinkqubo apho iiseli ziyekile ukwahlulahlula. Umonakalo ongalungiswanga we-DNA okanye uxinzelelo lweselula lunokubangela ukuthomalalisa. Ukuguga ngokuqhelekileyo kuchazwa njengenkqubo yokuthotywa ngokuthe ngcembe kwemisebenzi ye-physiological kunye nobudala; ukubonakaliswa kwangaphandle kukutshintsha kwenyama okubangelwa ukulahlekelwa kwemisipha kunye namathambo, kwaye ukubonakaliswa kwangaphakathi kuyancipha i-basal metabolism kunye nokusebenza komzimba.
Iingcali zenzululwazi ziye zafunda abantu abaphila ixesha elide, kwaye iziphumo zophando zibonisa ukuba kukho i-gene ehambelana nokuphila ixesha elide kubantu abaphila ixesha elide - "i-Sirtuins gene". Lo mfuzo uya kuthatha inxaxheba kwinkqubo yokulungiswa kokunikezelwa kwamandla omzimba kunye nokuphindaphinda kwe-DNA ukugcina ingqibelelo kunye nokuzinza kwe-gene, ukususa iiseli eziguga, ukuphucula amajoni omzimba ngokusebenzisa i-anti-inflammatory and antioxidant effects, kunye nokulibazisa ukuguga kweeseli eziqhelekileyo.
Ekuphela kwento ekujoliswe kuyo yemfuza yokuphila ixesha elide "Sirtuins" -NAD+
I-NAD+ ibalulekile ekugcineni impilo yomzimba kunye nokulungelelana. I-Metabolism, i-redox, ukugcinwa kwe-DNA kunye nokulungiswa, ukuzinza kwe-gene, ukulawulwa kwe-epigenetic, njl. zonke zifuna ukuthatha inxaxheba kwe-NAD +.
I-NAD + igcina unxibelelwano lweekhemikhali phakathi kwe-nucleus kunye ne-mitochondria, kwaye unxibelelwano olubuthathaka luyimbangela ebalulekileyo yokuguga kwamaselula.
I-NAD+ inokususa inani elandayo leekhowudi ze-DNA ezingalunganga ngexesha le-cell metabolism, igcine ukubonakaliswa okuqhelekileyo kwemfuza, igcine ukusebenza okuqhelekileyo kweeseli, kwaye icothise ukuguga kweeseli zomntu.
Lungisa umonakalo weDNA
I-NAD + i-substrate ebalulekileyo ye-DNA yokulungisa i-enzyme ye-PARP, enempembelelo ebalulekileyo ekulungisweni kwe-DNA, ukubonakaliswa kofuzo, ukuphuhliswa kweeseli, ukusinda kweeseli, ukwakhiwa kwakhona kwe-chromosome, kunye nokuzinza kwemfuza.
Sebenzisa iprotheni yokuphila ixesha elide
IiSirtuins zihlala zibizwa ngokuba lusapho lweprotheyini yokuphila ixesha elide kwaye zidlala indima ebalulekileyo yolawulo kwimisebenzi yeeseli, njengokudumba, ukukhula kweeseli, isigqi esijikelezayo, i-metabolism yamandla, umsebenzi we-neuronal, kunye nokumelana noxinzelelo, kwaye i-NAD + yi-enzyme ebalulekileyo yokwenziwa kweeproteni zobomi obude. . Yenza kusebenze zonke iiprotheyini ezi-7 zobomi obude emzimbeni womntu, zidlala indima ebalulekileyo ekuxhathiseni uxinzelelo lweselula, i-metabolism yamandla, ukuthintela ukuguquka kweeseli, i-apoptosis kunye nokuguga.
Nika amandla
Ibangela ukuveliswa kwamandla angaphezu kwama-95% afunekayo kwimisebenzi yobomi. I-Mitochondria kwiiseli zomntu zizityalo zamandla kwiiseli. I-NAD + yi-coenzyme ebalulekileyo kwi-mitochondria ukuvelisa i-molecule yamandla i-ATP, iguqula izondlo zibe amandla afunwa ngumzimba womntu.
Ukukhuthaza ukuvuselelwa kwemithambo yegazi kunye nokugcina ukunwebeka kwemithambo yegazi
Imithambo yegazi zizicubu eziyimfuneko kwimisebenzi yobomi. Njengoko sikhula, imithwalo yegazi ngokuthe ngcembe ilahlekelwa ukuguquguquka kwayo kwaye ibe nzima, iyancipha, kwaye iyancipha, ibangela "i-arteriosclerosis." I-NAD + inokonyusa umsebenzi we-elastin kwimithambo yegazi, ngaloo ndlela igcina ukuqina kwemithambo yegazi kunye nokugcina impilo yemithambo yegazi.
Ukukhuthaza imetabolism
I-Metabolism sisimbuku seentshukumo ezahlukeneyo zeekhemikhali emzimbeni. Umzimba uya kuqhubeka nokutshintshisa izinto kunye namandla. Xa olu tshintshiselwano luyekile, ubomi bomzimba buya kuphela.
UNjingalwazi Anthony kunye neqela lakhe lophando kwiYunivesithi yaseCalifornia, eU.SA, bafumanisa ukuba i-NAD+ inokuphucula ngokufanelekileyo ukucotha kwemetabolism yeeseli ezinxulumene nokuguga, ngaloo ndlela iphucula impilo yabantu kunye nokwandisa ubomi.
Khusela impilo yentliziyo
Intliziyo lelona lungu libalulekileyo ebantwini, kwaye inqanaba leNAD + emzimbeni lidlala indima ebalulekileyo ekugcineni ukusebenza kwentliziyo okuqhelekileyo. Ukwehliswa kwe-NAD + kunokunxulumana ne-pathogenesis yezifo ezininzi zentliziyo, kwaye inani elikhulu lezifundo ezisisiseko nazo ziqinisekisile isiphumo sokongeza i-NAD + kwizifo zentliziyo.
Ukuthintela izifo ze-cardiovascular and cerebrovascular
Uphononongo lubonise ukuba phantse zonke ii-subtypes ezisixhenxe ze-sirtuins (SIRT1-SIRT7) zihambelana nokuvela kwesifo senhliziyo. I-Sirtuins ithathwa njengeethagethi ze-agonistic kunyango lwezifo ze-cardiovascular, ngakumbi i-SIRT1.
I-NAD+ kuphela kwe-substrate ye-Sirtuins. Ukongezwa kwangexesha kwe-NAD + emzimbeni womntu kunokuwenza usebenze ngokupheleleyo uhlobo ngalunye lwe-Sirtuins, ngaloo ndlela lukhusela impilo yentliziyo kunye nokuthintela izifo zentliziyo.
Ukukhuthaza ukukhula kweenwele
Esona sizathu siphambili sokulahleka kweenwele kukulahleka kweenwele zikamama weseli, kwaye ukulahleka kobunzima bomzimba kamama kungenxa yokuba inqanaba leNAD + emzimbeni womntu liyehla. Iiseli zikamama weenwele azinayo i-ATP eyaneleyo yokwenza iprotein synthesis yeenwele, ngaloo ndlela zilahlekelwa ngamandla kwaye zikhokelela ekulahlekeni kweenwele. Ke ngoko, ukongeza i-NAD + kunokomeleza umjikelo we-asidi kwaye kuvelise i-ATP, ukuze iiseli zikamama weenwele zibe namandla okwaneleyo okuvelisa iprotein yeenwele, ngaloo ndlela kuphuculwe ukulahleka kweenwele.
I-NAD + unyango lwe-cell molekyuli
Njengoko iminyaka ikhula, inqanaba le-NAD + (Coenzyme I) emzimbeni liya kuwisa iliwa, elikhokelela ngokuthe ngqo ekusebenzeni komzimba kunye nokuguga kweeseli! Emva kweminyaka ephakathi, inqanaba le-NAD + emzimbeni womntu liyehla unyaka nonyaka. Ngeminyaka eyi-50, inqanaba le-NAD + emzimbeni lisiqingatha salo kwiminyaka eyi-20. Ngeminyaka eyi-80, amanqanaba e-NAD + amalunga ne-1% kuphela yento ababeyiyo kwiminyaka eyi-20.
Ke, i-NAD + yomgubo yahluke njani kwezinye izongezo kwimarike? Makhe sijonge ngakumbi imiba ephambili ekufuneka siyiqwalasele:
1. Ukufumaneka kwezinto eziphilayo:
Omnye wowona mahluko uphambili phakathi kwe-NAD+ umgubo kunye nezinye izongezo kubukho bayo bendalo. I-NAD+ powder ifunxwa lula ngumzimba kwaye isebenzise ngokufanelekileyo i-coenzymes. Kwelinye icala, ezinye izongezo zinokuba ne-bioavailability esezantsi, okuthetha ukuba umzimba awunakukwazi ukufunxa kwaye usebenzise izithako ezisebenzayo ngokufanelekileyo.
2. Indlela yokwenza:
I-NAD+ powder isebenza ngokuzalisa amanqanaba e-NAD+ emzimbeni, ngaloo ndlela ixhasa imisebenzi eyahlukeneyo yeselula. Ezinye izongezo zinokuba neendlela ezahlukeneyo zokwenza, zijolise kwiindlela ezithile okanye iinkqubo emzimbeni. Ukuqonda iindlela ezithile zokusebenza zezongezelelo ezahlukeneyo kunokukunceda ukuba ubone ukuba zeziphi ezona zilungele iimfuno zakho.
3. Uphando kunye nobungqina:
Xa kuqwalaselwa nayiphi na isongezelelo, kubalulekile ukuphonononga uphando olukhoyo kunye nobungqina obuxhasa ukusebenza kwayo kunye nokhuseleko. I-NAD + powder ibe ngumxholo wezifundo ezininzi, igxininisa izibonelelo zayo ezinokuthi zibekho kwimpilo yeselula kunye nokuphila ixesha elide. Kwelinye icala, ezinye izongezo zinokuba nophando olulinganiselweyo lokuxhasa amabango abo. Ukuqonda ubungqina besayensi emva kwesongezo kunokukunceda wenze izigqibo ezinolwazi malunga nokusetyenziswa kwayo.
4. Iimfuno zobuqu kunye neenjongo:
Ekugqibeleni, isigqibo sokusebenzisa i-NAD + powder okanye ezinye izongezo kufuneka zisekelwe kwiimfuno zakho kunye neenjongo zempilo. Cinga ngokubonisana nengcali yezempilo okanye ingcali yezondlo ukuze ubone ukuba zeziphi izongezo ezinokuba luncedo kuwe. Izinto ezinje ngobudala, indlela yokuphila, kunye neemeko zempilo ezikhoyo zinokudlala indima ekumiseleni eyona rejimeni yokongeza ifanelekileyo.
I-NAD +, izazinzulu ziye zayifunda iminyaka eyi-100. I-NAD+ ayisiyonto intsha yokufunyanwa, kodwa yinto efundwe ngaphezulu kweminyaka eli-100.
I-NAD + yafunyanwa okokuqala ngo-1904 yingcali yebhayoloji yaseBritane uSir Arthur Harden, owathi kamva waphumelela ibhaso leNobel kwiChemistry ngo-1929.
Ngo-1920, uHans von Euler-Chelpin wakhetha yedwa kwaye wayicoca i-NAD+ okokuqala kwaye wafumanisa isakhiwo sayo se-dinucleotide, emva koko waphumelela ibhaso leNobel kwiKhemistry ngo-1929.
Ngo-1930, u-Otto Warburg waqala wafumanisa indima ephambili ye-NAD+ njenge-coenzyme kwizinto eziphathekayo kunye ne-metabolism yamandla, kwaye kamva waphumelela ibhaso leNobel kuNyango ngo-1931.
Kwi-1980, uGeorge Birkmayer, uprofesa kwiSebe leKhemistry yezoNyango kwiYunivesithi yaseGraz e-Austria, waqala ukufaka isicelo sokunciphisa i-NAD + kunyango lwezifo.
Kwi-2012, iqela lophando likaLeonard Guarente, iqela lophando lwe-chemist eyaziwayo emhlabeni jikelele uStephen L. Helfand, kunye neqela lophando likaHaim Y. Cohen ngokulandelanayo lafumanisa ukuba i-NAD + inokwandisa iintonga zeCaenorhabditis elegans. Ubomi be-nematodes buphantse bube ngama-50%, bunokwandisa ubomi beempukane zeziqhamo malunga ne-10% -20%, kwaye inokwandisa ubomi beempuku eziyindoda ngaphezulu kwe-10%.
Uphononongo lwezazinzulu kunye nophando ngobomi zihlaziywa rhoqo kwaye ziphindaphindwa. NgoDisemba 2013, uDavid Sinclair, unjingalwazi wezofuzo kwiYunivesithi yaseHarvard, wapapasha "Ukongeza i-NAD nge-NAD" kwiphephancwadi lezemfundo eliphezulu lehlabathi elithi "Cell". "Emva kweveki enye yokunyusa i-NAD kunye ne-arhente, ixesha lokuphila kweegundane landiswa nge-30%. Iziphumo zophando zityhilwe okokuqala ukuba izongezo ze-NAD+ zinokubuyisela umva ukuguga kwaye zandise ubude bobomi. Olu phando lothusa ihlabathi kwaye lwavula indlela yodumo lwezongezelelo ze-NAD njengezinto ezichasene nokuguga. .
Ngokufunyaniswa okumangalisayo, i-NAD + iseke unxibelelwano olungenakwahlulwa kunye nokuchasana nokuguga. Kwiminyaka yakutshanje, uphando nge-NAD+ luphantse lwalawula iijenali zezemfundo ze-SCI ezinje ngeSayensi, iNdalo, kunye neCell, iye yaba yeyona nto ifunyaniswayo ichukumisayo kuluntu lwezonyango. Kuthiwa oku Linyathelo eliyimbali elathathwa luluntu kuhambo lokulwa nokwaluphala nokwandisa ixesha lokuphila.
1. Phanda ngodumo lwebrendi kunye nokungafihli nto
Xa kuqwalaselwa uphawu oluthile lwe-NAD+ yomgubo, kufanelekile ukuphanda isidima senkampani kunye nokungafihli nto. Khangela iibrendi ezibeka phambili ukungafihli kwiinkqubo zabo zokufumana kunye nemveliso. Iibrendi ezithembekileyo ziya kubonelela ngolwazi oluneenkcukacha malunga ne-NAD + yabo yokufumana umgubo, kubandakanya nomgangatho wezinto ezikrwada kunye nemigangatho yokwenziwa ababambelela kuyo. Ukongeza, jonga uphononongo lwabathengi kunye nobungqina bokuvavanya ukwaneliseka ngokubanzi kwabanye abasebenzisi kunye namava ngeemveliso zophawu.
2. Vavanya ukucoceka kwe-NAD + powder
Ubunyulu yinto ephambili xa ukhetha uphawu lwe-NAD + powder. Umgangatho ophezulu we-NAD + powder kufuneka ungabinazingcolisi kunye nezihluzi, uqinisekise ukuba ufumana imveliso ecocekileyo nesebenzayo. Jonga iibrendi eziqhuba uvavanyo lomntu wesithathu ukuqinisekisa ubunyulu be-NAD + yabo engumgubo. Uvavanyo lomntu wesithathu lunikeza isiqinisekiso esongezelelweyo sokuba iimveliso zihlangabezana nemigangatho ephezulu yokucoceka kwaye aziqukethe izinto ezinobungozi.
3. Ukuqwalasela iinkqubo zokuvelisa kunye nemigangatho yomgangatho
Inkqubo yokuvelisa idlala indima ebalulekileyo kumgangatho we-NAD + powder. Khetha iibrendi ezilandela imilinganiselo engqongqo yolawulo lomgangatho kwaye ubambelele kwiiNdlela eziLungileyo zokuVelisa (GMP). Isiqinisekiso se-GMP siqinisekisa ukuba iimveliso ziveliswa kwindawo ecocekileyo nelawulwayo, ukunciphisa umngcipheko wongcoliseko kunye nokuqinisekisa umgangatho ongaguqukiyo. Ukongeza, buza malunga nokuzinikela kwebhrendi kuzinzo kunye nezenzo zokukhangela ezisesikweni, njengoko ezi zinto zinokubonisa umgangatho uwonke wemveliso.
4. Vavanya i-bioavailability kunye ne-absorption ye-NAD + powder
I-Bioavailability ibhekisa kumandla omzimba okufunxa kunye nokusebenzisa izithako ezisebenzayo kwisongezelelo. Xa ukhetha uphawu lwe-NAD + powder, qwalasela i-bioavailability yemveliso. Jonga iibrendi ezisebenzisa iinkqubo zonikezelo ezikumgangatho ophezulu okanye itekhnoloji ukonyusa i-NAD + bioavailability. Oku kunokubandakanya iimpawu ezinje nge-micronization okanye i-encapsulation, enokuphucula ukufunxwa kwe-NAD + emzimbeni, ekugqibeleni yandise ukusebenza kwayo.
5. Funa uphando lwezenzululwazi kunye nophando lweklinikhi
Iimpawu ezithembekileyo ze-NAD+ zomgubo zibonelela ngezifundo zesayensi kunye nezonyango ukuxhasa ukusebenza kunye nokhuseleko lweemveliso zabo. Khangela iimpawu ezityala imali kuphando kunye nophuhliso, njengoko oku kubonisa ukuzibophelela ekuveliseni umgangatho ophezulu kunye neemveliso ezisekelwe kubungqina. Ukuqinisekiswa kwezenzululwazi kuqinisekisa ukuba i-NAD + powder iye yavavanywa ngokungqongqo kunye novavanyo, iqinisekisa ngakumbi umgangatho kunye nokucoceka kwayo.
I-Suzhou Myland Pharm & Nutrition Inc. ibandakanyeke kwishishini lokongezelela isondlo ukususela ngo-1992. Yinkampani yokuqala e-China ukuphuhlisa nokuthengisa isicatshulwa sembewu yomdiliya.
Iminyaka engama-30 yamava kwaye iqhutywa bubuchwephesha obuphezulu kunye nesicwangciso se-R&D esiphuculwe kakhulu, inkampani iphuhlise uluhlu lweemveliso ezikhuphisanayo kwaye ibe sisongezelelo sesayensi yobomi, ukuhlanganiswa kwesiko kunye nenkampani yeenkonzo zokuvelisa.
Ukongeza, iSuzhou Myland Pharm & Nutrition Inc. ikwangumvelisi obhalisiweyo we-FDA. Izixhobo zeR&D zenkampani, izixhobo zemveliso, kunye nezixhobo zohlalutyo zezanamhlanje kwaye zinemisebenzi emininzi kwaye zinokuvelisa iikhemikhali ukusuka kwimilligram ukuya kwiitoni kwisikali, kwaye zithobela imigangatho ye-ISO 9001 kunye neenkcukacha zemveliso ye-GMP.
Umbuzo: Ziziphi izongezo ze-NAD + ezisetyenziselwa ntoni?
A: isongezelelo se-NAD + sisongezelelo sesondlo esongeza i-coenzyme NAD + (nicotinamide adenine dinucleotide). I-NAD + idlala indima ebalulekileyo kwimetabolism yamandla kunye nokulungiswa kweeseli ngaphakathi kweeseli.
Umbuzo: Ngaba izongezo ze-NAD + zisebenza ngokwenene?
A: Olunye uphando lucebisa ukuba izongezo ze-NAD + zinokunceda ukuphucula i-metabolism yamandla eselula kwaye icothise inkqubo yokuguga.
Umbuzo:Yeyiphi imithombo yokutya ye-NAD+?
A: Imithombo yokutya ye-NAD + ibandakanya inyama, intlanzi, iimveliso zobisi, iimbotyi, amantongomane kunye nemifuno. Oku kutya kuqulathe ngakumbi i-niacinamide kunye ne-niacin, enokuthi iguqulwe ibe yi-NAD + emzimbeni.
Umbuzo: Ndikhetha njani isongezelelo se-NAD +?
A: Xa ukhetha izongezelelo ze-NAD +, kuyacetyiswa ukuba uqale ufune iingcebiso kugqirha okanye kwisondlo sokutya ukuze uqonde iimfuno zakho zesondlo kunye nesimo sempilo. Ukongeza, khetha uphawu oluthembekileyo, jonga izithako zemveliso kunye nedosi, kwaye ulandele isikhokelo sedosi kwi-insert yemveliso.
Ukuziphendulela: Eli nqaku lelolwazi ngokubanzi kuphela kwaye akufanele lithathwe njengeliphi na icebiso lonyango. Olunye ulwazi lweposti yebhlog luvela kwi-Intanethi kwaye alunamsebenzi. Le webhusayithi inoxanduva kuphela lokuhlela, ukufomatha kunye nokuhlela amanqaku. Injongo yokudlulisa ulwazi olongezelelekileyo ayithethi ukuba uyavumelana neembono zayo okanye uqinisekise ubunyani bomxholo wayo. Soloko udibana nengcali yezempilo ngaphambi kokuba usebenzise naziphi na izongezo okanye wenze utshintsho kwirejimeni yokhathalelo lwempilo.
Ixesha lokuposa: Aug-05-2024
