I-Spermine Tetrahydrochloride (SPT) umenzi we-powder CAS No.: 306-67-2 98.0% ubumsulwa min. zokongeza izithako
Iiparamitha zeMveliso
Igama lemveliso | N,N'-bis(3-aminopropyl)butane-1,4-diamine,tetrahydrochloride |
Elinye igama | 1,4-Butanediamine,N,N'-bis(3-aminopropyl)-,tetrahydrochloride;Gerontine tetrahydrochloride; |
Inombolo yeCAS. | 306-67-2 |
Ifomula yemolekyuli | I-C10H30Cl4N4 |
Ubunzima bemolekyuli | 348.18 |
Ubunyulu | 98% |
Imbonakalo | off-white solid |
Ukupakisha | 1kg/ibhegi |
Isicelo | Ukuchasa ukuguga kunye nokuPhuculwa koBuchule boBuchule |
Intshayelelo yeMveliso
I-Spermine tetrahydrochloride yikhompawundi edlala indima ephambili kwiinkqubo ezahlukeneyo zebhayoloji. Iphuma kwi-spermine, kodwa ine-chloride ion ezine zongezwa. Oku kuguqulwa kuncinci kunokuchaphazela kakhulu iimpawu kunye nokusebenza kwayo. I-Spermine tetrahydrochloride yi-polyamine, iqela lezinto eziphilayo ezinamaqela amaninzi e-amino. Iipolyamines ziyimfuneko ekukhuleni kweeseli kunye nokuphila kwaye zibandakanyeka kwiinkqubo ezahlukeneyo zeselula, kubandakanywa ukuphindaphinda kwe-DNA, ukubhalwa kunye nokuguqulelwa. Omnye wemisebenzi ephambili ye-spermine tetrahydrochloride kukukwazi ukuzinzisa iDNA. Ikwenza oku ngokubophelela kumaqela e-phosphate ahlawuliswa kakubi e-DNA, ingathathi hlangothi intlawulo yayo kunye nokukhuthaza ukubunjwa kwezakhiwo ze-DNA ezizinzileyo kunye ne-compact. Olu uzinzo lubalulekile ekupakishweni okufanelekileyo kwe-DNA kunye nentlangano, ekugqibeleni ichaphazela ukubonakaliswa kofuzo kunye nokusebenza kwamaselula. Ukongezelela, i-spermine tetrahydrochloride ibandakanyeka ekulawuleni umsebenzi we-enzyme. Iyakwazi ukusebenzisana kunye ne-enzymes kwaye imodareyithe umsebenzi wabo ngokuguqula isakhiwo sabo okanye ichaphazele umsebenzi wabo we-catalytic. Le nkqubo ibalulekile ekugcineni i-homeostasis yeselula kunye nokuqinisekisa ukusebenza ngokufanelekileyo kweendlela ze-enzymatic. I-Spermine tetrahydrochloride nayo idlala indima ekubonakalisweni kweeseli kunye nokuzinza kwe-membrane. Iyakwazi ukusebenzisana ne-phospholipids, inxalenye ephambili yeembrane zeseli. Oku kusebenzisana kunceda ukugcina ingqibelelo ye-membrane yeseli kwaye ilawula ukuthuthwa kwama-molecule ngaphakathi nangaphandle kweseli.
Uphawu
(1) Ukucoceka okuphezulu: I-Spermine tetrahydrochloride inokufumana iimveliso ezicocekileyo ngokucokisa iinkqubo zokuvelisa. Ukucoceka okuphezulu kuthetha ukuba ngcono kwe-bioavailability kunye neempendulo ezimbalwa ezimbi.
(2) Ukhuseleko: I-Spermine tetrahydrochloride yimveliso yendalo kwaye ibonakaliswe ukuba ikhuselekile kumzimba womntu.
(3) Ukuzinza: I-Spermine tetrahydrochloride inozinzo oluhle kwaye inokugcina umsebenzi wayo kunye nesiphumo phantsi kweemeko ezahlukeneyo kunye neemeko zokugcina.
(4) Kulula ukufunxa: I-Spermine tetrahydrochloride inokuthatyathwa ngokukhawuleza ngumzimba womntu kwaye isasazwe kwizicubu ezahlukeneyo kunye namalungu.
Usetyenziso
I-Spermine tetrahydrochloride iyikhompawundi ebalulekileyo enceda kwiinkqubo ezahlukeneyo zebhayoloji. Njengesongezelelo sokutya, ukongeza kwimisebenzi yayo ye-physiological, i-spermine tetrahydrochloride ifundwe ngezicelo zayo ezinokubakho ze-biomedical. Ukongezelela, i-spermine tetrahydrochloride ifundelwe iipropathi zayo ze-antimicrobial. Kuye kwaboniswa ukuba kuneempembelelo zokuthintela kwiintlobo ze-microorganisms, kuquka ibhaktheriya, i-fungi, kunye neentsholongwane. Ikhono layo lokuzinzisa i-DNA, ukulawula umsebenzi we-enzyme, kunye nokuchaphazela ukubonakaliswa kweeseli kunye nokuzinza kwe-membrane kwenza kube ngumdlali oyintloko kumsebenzi weselula kunye ne-homeostasis.