Yintoni ekufuneka uyazi malunga nokuguga kwaye zeziphi iindlela onokuthi uzithathe ukuze unciphise

Njengoko abantu bekhula, abaninzi bafuna iindlela zokunciphisa inkqubo kunye nokugcina inkangeleko yobutsha kunye namandla. Kukho izicwangciso ezahlukeneyo kunye nobuchule obunokusetyenziswa ukunceda ukucotha inkqubo yokuguga kunye nokukhuthaza impilo yonke kunye nokuphila kakuhle.

Uphando lwamva nje lubonisa ukuba ukuguga akwenzeki nje ngokuthe ngcembe, kodwa kuphinda kuqhamuke ngexesha elithile phakathi kweminyaka engama-44 ukuya kwengama-60.

Ukuqala kwi-40 yakho yokuqala, i-lipid yakho kunye ne-alcohol metabolism iyatshintsha, ngelixa umsebenzi wakho wezintso, i-carbohydrate metabolism, kunye nokulawulwa kwe-immune iqala ukuhla malunga ne-60 yobudala. indala.

Uphononongo lubandakanya kuphela i-108 yaseCalifornian abaneminyaka eyi-25 ukuya kwi-75, kwaye uphando olungakumbi luyafuneka ukuze kuqinisekiswe iziphumo. Nangona kunjalo, ezi ziphumo zinokukhokelela kuvavanyo olutsha lokuxilonga kunye nezicwangciso zokuthintela izifo ezinxulumene nokuguga.

Ubomi obude abuthethi ukuba ubomi obudala obunempilo okanye obusebenzayo. Ngokutsho kombhali ophezulu wokufunda uGqr. Michael Snyder, umlawuli weZiko leGenomics kunye neMedicalized Personalized kwiYunivesithi yaseStanford, kubantu abaninzi, umyinge wabo "wezempilo" - ixesha abalichitha kwimpilo enhle - lide kunokuba ubomi babo bufutshane. I-11-15 iminyaka.

Ubomi obuphakathi bubalulekile ekugugeni okunempilo

Uphando lwangaphambili lubonise ukuba impilo yakho phakathi kwe-midlife (ngokuqhelekileyo phakathi kweminyaka eyi-40 kunye ne-65) idlala indima ebalulekileyo kwimpilo yakho kamva ebomini. Uphononongo luka-2018 kwijenali yeNutrition yanxibelelanisa izinto ezithile zokuphila kubomi obuphakathi, njengobunzima obunempilo, ukusebenza ngokomzimba, ukutya ukutya okulungileyo kunye nokungatshayi, ukuphucula impilo ngexesha lokuguga. 2

Ingxelo epapashwe kwijenali ka-2020 ikwabonise ukuba ubomi obuphakathi lixesha elibalulekileyo lokutshintsha impilo yengqondo. Ukulawula uxinzelelo lwegazi kunye nokuhlala kwintlalontle, ukuqonda kunye nokusebenza ngokomzimba ngeli nqanaba lobomi kunokuncedisa ukunciphisa umngcipheko we-dementia kamva ebomini, ingxelo ithi.

Uphononongo olutsha longeza kwintsimi yophando lwezempilo kwaye lugxininisa ukubaluleka kokuphuhlisa imikhwa ethile yokuphila kwasekuqaleni ebomini.

"Usempilweni kangakanani xa uneminyaka engama-60, i-70 okanye i-80 ixhomekeke kwinto oyenzileyo kumashumi eminyaka ngaphambi kwakho," utshilo uKenneth Boockvar, MD, umlawuli weZiko loPhando oluDityanisiweyo lokuguga kwiYunivesithi yaseAlabama. eBirmingham. ” kodwa akazange abandakanyeke kweso sifundo.

Wongezelela ukuba kwakusekude kakhulu ukwenza iingcebiso ezithile ezisekelwe kuphando olutsha, kodwa ukuba abantu abafuna ukuhlala bephilile kwi-60 yabo kufuneka baqale ukunikela ingqalelo ekudleni kwabo kunye nendlela yokuphila kwi-40 yabo kunye ne-50.

Ukuguga akunakuphepheka, kodwa ukutshintsha kwendlela yokuphila kunokwandisa ubomi obunempilo

Uphando olutsha lufumanisa ukuba iimolekyuli kunye ne-microorganisms ezinxulumene nokuguga ziyancipha ngexesha lezigaba ezithile zomjikelo wobomi, kodwa uphando lwexesha elizayo luyafuneka ukufumanisa ukuba utshintsho olufanayo lweemolekyuli lwenzeka kubantu abahlukeneyo.

“Sifuna ukuhlalutya abantu abaninzi kwilizwe liphela ukuze sibone ukuba izinto esiziqwalaselayo ziyasebenza na kuye wonke umntu - hayi nje abantu abakwiBay Area,” utshilo uSnyder. "Sifuna ukuhlalutya ukungafani phakathi kwamadoda nabasetyhini. Abasetyhini bahlala ixesha elide kwaye sifuna ukuqonda ukuba kutheni."

Ukuguga akunakuphepheka, kodwa utshintsho oluthile lwendlela yokuphila lunokunceda ukunciphisa umngcipheko wezifo ezinxulumene nokuguga. Nangona kunjalo, ezinye izinto ezininzi ezifana nokusingqongileyo, uzinzo lwezemali, ukhathalelo lwempilo kunye namathuba emfundo nazo zinefuthe kwiziphumo zokuguga okunempilo kwaye kunzima ukuba abantu balawule.

Abantu banokwenza utshintsho oluncinci lokuphila olufana nokuhlala be-hydrated ukugcina impilo yezintso, ukwakha ubunzima be-muscle ngokuqeqeshwa kwesisindo kunye nokuthatha imithi ye-cholesterol ukuba i-cholesterol ye-LDL iphakanyisiwe, uSnyder uthe.

Wongeze wathi: “Oku kusenokungayeki ukwaluphala, kodwa kuya kunciphisa iingxaki esizibonayo kwaye kuncede ukwandisa ubomi babantu obusempilweni.

Yintoni enokwenziwa ukulibazisa ukwaluphala?

Enye yezona zinto zibalulekileyo ekuthobeni ukuguga kukugcina impilo esempilweni. Oku kuquka ukutya ukutya okunesondlo okuneziqhamo, imifuno, ukutya okuziinkozo kunye neeprotheni ezibhityileyo. Ukuphepha ukutya okucutshungulwayo, iswekile eninzi, kunye namafutha angenampilo kunokunceda ukunciphisa ukuvuvukala emzimbeni kunye nokuxhasa impilo yonke. Ukuhlala u-hydrated ngokusela amanzi amaninzi nako kubalulekile ekugcineni ulusu olusempilweni kunye namalungu.

Ukuzilolonga rhoqo lelinye icandelo eliphambili lendlela yokuphila enempilo kwaye kunokunceda ukuthothisa inkqubo yokuguga. Umsebenzi womzimba unceda ukuphucula impilo ye-cardiovascular, ukugcina ubunzima bemisipha, kunye nokuxhasa ukuhamba ngokubanzi kunye nokuguquguquka. Ukuthatha inxaxheba kwimisebenzi efana nokuhamba, ukubhukuda, i-yoga okanye ukuqeqeshwa kwamandla kunokunceda umzimba wakho ubonakale umncinci kwaye unamandla.

Ukongeza kokutya kunye nokuzilolonga, ukulawula uxinzelelo kubalulekile ekunciphiseni ukuguga. Ukuxinezeleka okungapheliyo kunokuba nemiphumo emibi emzimbeni, okukhokelela ekwandeni kokuvuvukala kunye nobuthathaka bomzimba. Ukuziqhelanisa neendlela zokunciphisa uxinzelelo ezifana nokucamngca, ukuphefumla okunzulu, okanye ukucinga ngengqondo kunokunceda ukukhuthaza ukuphumla kunye nokuphila kakuhle.

Enye inkalo ebalulekileyo yokunciphisa ukwaluphala kukulala ngokwaneleyo. Ukulala kubalulekile ukuze umzimba ulungiswe uze uhlaziyeke, yaye ukungalali kakuhle kunokukhokelela ekubeni umntu aguge ngaphambi kwexesha. Ukuseka ishedyuli yokulala rhoqo kunye nokudala ixesha lokulala elipholileyo kunokuncedisa ukuphucula umgangatho wokulala kunye nokuxhasa impilo yonke.

Ukongeza kwizinto zendlela yokuphila, kukho iindlela ezahlukeneyo zonyango ezinokuthi zithobe inkqubo yokuguga. Oku kunokubandakanya iindlela zokunyamekela ulusu, iinkqubo zokuthambisa, kunye nokungenelela kwezonyango. Ukusebenzisa i-sunscreen kunye nokuthambisa ulusu lwakho kunokunceda ukuthintela umonakalo welanga kunye nokugcina inkangeleko yobutsha. Iinkqubo zokuthambisa ezifana ne-Botox, iifayili, kunye nonyango lwe-laser zinokunceda ukunciphisa ukubonakala kwemibimbi kunye nemigca emihle.

Ukongeza, kukho izongezo ezichasene nokuguga ezikhoyo ezinokuthi zixhase impilo yonke kunye namandla. Phakathi kwezongezo ezinobungqina bezenzululwazi ukuxhasa indima yabo ekuphuculeni impilo ye-mitochondrial kunye nokucotha ukuguga zii-NAD+ precursors kunye ne-urolithin A.

NAD + izongezo

Apho kukho i-mitochondria, kukho i-NAD + (nicotinamide adenine dinucleotide), imolekyuli eyimfuneko yokwandisa imveliso yamandla. I-NAD + ngokwendalo iyehla ngeminyaka, ebonakala ihambelana nokuhla okunxulumene nobudala kumsebenzi we-mitochondrial.

Uphando lubonisa ukuba ngokunyusa i-NAD +, unokuphucula imveliso yamandla e-mitochondrial kwaye uthintele uxinzelelo olunxulumene nobudala. I-NAD + ye-precursor supplement inokuphucula ukusebenza kwezihlunu, impilo yobuchopho, kunye nemetabolism ngelixa kunokulwa nezifo ze-neurodeergenerative. Ukongezelela, banciphisa ubunzima bomzimba, baphucula ukuvakalelwa kwe-insulin, kunye nokunciphisa amanqanaba e-lipid, njengokunciphisa i-cholesterol ye-LDL.

Coenzyme Q10

Njenge-NAD +, i-coenzyme Q10 (CoQ10) idlala indima ethe ngqo kunye nebalulekileyo kwimveliso yamandla e-mitochondrial. Njenge-astaxanthin, i-CoQ10 inciphisa uxinzelelo lwe-oxidative, i-byproduct yemveliso yamandla e-mitochondrial eba mbi ngakumbi xa i-mitochondria ingekho mpilweni. Ukongezwa nge-CoQ10 kunciphisa umngcipheko wokuhlaselwa yintliziyo, ukubetha kunye nokufa. Ukuthathela ingqalelo ukuba i-CoQ10 iyancipha ngeminyaka, ukongeza kwi-CoQ10 kunokubonelela ngezibonelelo zobomi obude kubantu abadala.

Urolithin A

I-Urolithin A (UA) iveliswa ziibhaktheriya zethu zamathumbu emva kokutya iipolyphenols ezifumaneka kukutya okunje ngeerharnati, amaqunube, kunye neewalnuts. Ukongezwa kwe-UA kwiimpuku ezineminyaka ephakathi kusebenzisa iisirtuins kwaye yonyusa i-NAD + kunye namanqanaba amandla eselula. Okubalulekileyo, i-UA ibonakaliswe ukuba isusa i-mitochondria eyonakeleyo kwizihlunu zomntu, ngaloo ndlela iphucula amandla, ukumelana nokudinwa, kunye nokusebenza kwembaleki. Ke ngoko, ukongezwa kwe-UA kunokwandisa ubomi ngokuchasana nokuguga kwemisipha.

I-Spermidine

Njenge-NAD + kunye ne-CoQ10, i-spermidine yimolekyuli yendalo eyehla ngokukhula. Ngokufana ne-UA, i-spermidine iveliswa yintsholongwane yethu yamathumbu kwaye ibangela i-mitophagy - ukususwa kwe-mitochondria engafanelekanga, eyonakalisiweyo. Izifundo zempuku zibonisa ukuba ukongezwa kwe-spermidine kunokukhusela kwisifo sentliziyo kunye nokuguga kwabasetyhini. Ukongezelela, i-spermidine yokutya (efumaneka kwiindidi zokutya ezibandakanya i-soy kunye neengqolowa) iphucule imemori kwiigundane. Uphando oluthe kratya luyafuneka ukufumanisa ukuba ezi ziphumo zinokuphinda-phinda ebantwini.

I-Suzhou Myland Pharm & Nutrition Inc. ngumvelisi obhalisiweyo we-FDA obonelela ngekhwalithi ephezulu kunye nokucoceka okuphezulu kwe-urolithin A powder.

ESuzhou Myland Pharm sizimisele ukubonelela ngezona mveliso zikumgangatho ophezulu ngamaxabiso angcono. I-Urolithin yethu ye-powder ihlolwe ngokugqithiseleyo ukucoceka kunye namandla, ukuqinisekisa ukuba ufumana isongezelelo esiphakamileyo esinokuthembela kuso. Nokuba ufuna ukuxhasa impilo yeselula, ukomeleza amajoni akho omzimba okanye ukuphucula impilo yonke, i-Urolithin A powder yethu lukhetho olugqibeleleyo.

Ineminyaka engama-30 yamava kwaye iqhutywa bubuchwepheshe obuphezulu kunye nezicwangciso ze-R&D eziphuculwe kakhulu, iSuzhou Myland Pharm iphuhlise uluhlu lweemveliso ezikhuphisanayo kwaye ibe sisongezelelo sesayensi yobomi, ukudibanisa isiko kunye nenkampani yeenkonzo zokuvelisa.

Ukongeza, iSuzhou Myland Pharm ikwangumvelisi obhalisiweyo we-FDA. Izixhobo ze-R&D zenkampani, izixhobo zemveliso, kunye nezixhobo zohlalutyo zezanamhlanje kwaye zinemisebenzi emininzi, kwaye zinokuvelisa iikhemikhali ukusuka kwimilligrams ukuya kwiitoni kwisikali, kwaye zithobela imigangatho ye-ISO 9001 kunye neenkcukacha zemveliso ye-GMP.