Yintoni iSqualene kwaye kutheni kufuneka ukhathalele?

Njengoko abantu bexhalabele ngakumbi ngempilo yabo, i-Squalene ifumana ukuthandwa ngenxa yeempawu zayo ezibalaseleyo zokuthambisa kunye ne-antioxidant. Njengekhompawundi eyenzeka ngokwemvelo, iSqualene isetyenziswa kakhulu kwiimveliso zokhathalelo lwesikhumba, izithambiso kunye nezongezo zokutya. Njengoko imfuno yabathengi yezithako zendalo iqhubeka ikhula, ngokunjalo imfuno ye-Squalene powder ephezulu kwimarike.

Squalene (I-CAS: 111-02-4) ngulwelo olunamafutha angenambala. Yiyo yonke i-trans triterpene ikhompawundi enesakhiwo se-isoprene kwaye iyinxalenye ebalulekileyo kwindlela ye-cholesterol yomntu. Ingundoqo ephakathi, i-terpenoids idla ngokufumaneka kwi-nutraceuticals kunye nezithambiso. Kukholelwa ukuba i-squalene ineenzuzo ezininzi kumzimba womntu, kubandakanya ukuthoba i-lipids yegazi, i-antioxidant, i-anti-inflammatory kunye ne-immunity-enhance effect. I-squalene inokuthatha inxaxheba kwi-metabolism njenge-precursor ye-steroid synthesis, kwaye idlala indima ebalulekileyo kwiindlela ze-synthesis ye-β-carotene, i-coenzyme Q10, i-vitamin D, i-vitamin E kunye ne-vitamin K1.

I-squalene ifumaneka ngokubanzi kwizilwanyana, izityalo kunye ne-microorganisms. Ihlanganiswe kwi-endoplasmic reticulum kwaye igcinwe kwii-vesicles okanye idluliselwe kwi-membrane yeseli ngokusebenzisa i-vesicles. Ngenxa yomsebenzi wayo onamandla webhayoloji, isetyenziswa kakhulu ekutyeni nakwizithambiso. Iindawo zoshishino. I-squalene ifumaneka kukutya okuninzi, phakathi kwayo i-oyile yesibindi se-shark iqukethe amanqanaba aphezulu, kwaye i-oyile yemifuno embalwa efana neoli yeoli kunye ne-rice bran oil iqulethe amanqanaba aphezulu e-squalene.

I-Squalene ineempembelelo ezininzi ze-bioactive, kubandakanywa nokuphucula ukunyamezela kwe-hypoxia, ukuvimbela ukukhula kwe-microbial, i-antibacterial and anti-inflammatory, kunye nokulawula i-cholesterol metabolism. Ukongeza, inamandla okucima ioksijini ye-singlett, ikhusela ngokufanelekileyo ulusu kwi-lipid peroxidation kunye nokukhusela iiseli kumonakalo owenziwe kwi-oxidative kwi-DNA. Le nto ikwabonisa imisebenzi eyahlukeneyo ebalulekileyo yomzimba efana nokuthintela isifo sentliziyo kunye nokuphucula ukhuseleko lomntu.

Intshayelelo kwimisebenzi ye-squalene

1. Umsebenzi we-Antioxidant

I-squalene inokuthintela ngokufanelekileyo ukusabela kweeradicals zamahhala emzimbeni womntu kwaye idlale indima ye-antioxidant. I-molecule ye-squalene iqulethwe ngamabhondi angama-6 angenayo i-unsaturated ephindwe kabini kwaye inezakhiwo ezinamandla ze-antioxidant.

2. I-Antibacterial and anti-inflammatory effects

I-Squalene ine-antibacterial, anti-inflammatory and bactericidal effects kwaye ingasetyenziselwa izifo zendlela yokuphefumula ephezulu kunye nezifo zesikhumba ezibangelwa yibhaktheriya, kunye nokutshisa, izilonda zesikhumba kunye nezifo ze-aphthous. Uphando lubonisa ukuba i-squalene inokukhawulezisa inkqubo yokuphulukisa amanxeba kunye namanxeba. Iipropathi zayo ezichasayo kunye ne-antioxidant zinceda ekubuyiseleni ngokukhawuleza, okwenza kube yinto ebalulekileyo yokongeza kuyo nayiphi na ikiti yoncedo lokuqala

3. I-scavenger ye-radical yasimahla, ukuphuculwa kwamajoni omzimba

I-squalene inesakhono esinamandla sokukhupha i-radical free kwaye idlala indima ebalulekileyo ekukhuthazeni imetabolism yabantu. Ngokusebenzisa i-metabolism, i-squalene inceda ukuphucula ukufunxa komzimba kunye nokusetyenziswa kakuhle kwezondlo, ngaloo ndlela ikhuthaza ukugcinwa kwempilo. Njengesongezo sokutya esisebenzayo, i-squalene isetyenziswa kwiimveliso ezahlukeneyo zempilo, ezinje ngezongezo zesondlo, ukutya okunempilo, kunye neziselo ezisebenzayo. Uphando kunye nokusetyenziswa kwe-squalene nazo zikhula rhoqo, zibonelela abantu ngamathuba amaninzi okufumana inzuzo yezempilo ngokutya.

4. Ukufuma kunye ne-antioxidant

I-squalene ineenzuzo ezininzi zempilo yesikhumba, kuquka ukukhuselwa kwimitha ye-UV kunye ne-antioxidant. Iphucula ukuthungwa kwesikhumba, inciphisa i-pores kunye nemibimbi, kwaye ithambisa ulusu ngaphandle kokubangela ukucaphuka. Uvavanyo kubasetyhini abangaphezu kweminyaka engama-50 ubudala lubonise ukuba ukuthatha i-squalene kunokunciphisa kakhulu imibimbi yobuso kunye nokuphucula irhashalala ebusweni kunye nebala. Ukongeza, i-squalene inokunyusa umsebenzi we-enzyme ye-antioxidant yesikhumba, kwaye umphumo ungcono kakhulu kune-vitamin E. Ngenxa yemiphumo emihle ye-emollient, ezinye iimpawu ze-cosmetic ezaziwayo ziye zayisebenzisa kwiimveliso zokunakekelwa kwesikhumba kunye neenwele ezifana ne-hydrating serums kunye nokunakekelwa kwesikhumba. iioli.

3. Isicelo soshishino lweSqualene

1). I-Squalene kunye neemveliso zayo ze-hydrogenated zithandwa kuluhlu lwazo olubanzi lwezicelo kwizinto zokuthambisa. I-squalene ineenzuzo ezininzi zempilo yesikhumba, kuquka ukukhuselwa kwimitha ye-UV kunye ne-antioxidant. Iphucula ukuthungwa kwesikhumba, inciphisa i-pores kunye nemibimbi, kwaye ithambisa ulusu ngaphandle kokubangela ukucaphuka.

2). Njenge-oyile yendalo, i-squalene isetyenziswa ngokubanzi njenge-biocompatible ichiza elithwala ukukhutshwa kwechiza okuqhubekayo. Amachiza e-emulsion aqukethe i-squalene anokwandisa isiqingatha sobomi bechiza.

3). I-Squalene ibonise amandla amaninzi okusebenza kuphando lwezonyango: kwiiseli ze-HepG2, ihlola indlela yokunciphisa i-cholesterol ngokuvimbela ukwanda kweeseli kunye nokwandisa i-LDLR ibonakaliso; okwesibini, izifundo ze-molecular docking zibonisa ukuba i-squalene ingaba nendima kunyango lomhlaza wolusu ukuze idlale indima; ekugqibeleni, ngokufakwa kwi-PLGA NPs, ukusebenza kakuhle kweselula kwioli yeoli yomnquma kuphuculwe, kwaye inamandla okugcina impilo yeseli kunye nokuxhathisa uxinzelelo lwe-oxidative.

4). Njengesongezo sokutya esisebenzayo, i-squalene iye yatsala ingqalelo enkulu kwaye ifundwe ngokubanzi ngendima yayo ekuthinteleni izifo zentliziyo, umhlaza kunye nezinye izifo.

Ungayithenga phi iSqualene?

Imiba ephambili ekuKhethweni koMboneleli weSqualene

1. Umgangatho wemveliso

Xa ukhetha umthengisi, into yokuqala ekufuneka uyiqwalasele ngumgangatho wemveliso. Ukucoceka okuphezulu kwe-Squalene powder iqinisekisa umsebenzi wayo we-biological kunye nokusebenza kakuhle. I-Squalene powder enikezwe ngu-Suzhou Myland iye yavavanywa ngokungqongqo umgangatho wokuqinisekisa ukuba ibhetshi nganye yeemveliso ihlangabezana nemigangatho yamazwe ngamazwe kwaye inomgangatho oqinisekisiweyo.

2. Umthamo wemveliso

Umthamo wemveliso yomenzi uchaphazela ngokuthe ngqo ixesha kunye nokuzinza kokubonelela. I-Suzhou Myland inezixhobo eziphambili zemveliso kunye nobuchwepheshe obunokuhlangabezana neemfuno zemveliso yobuninzi, iqinisekisa ukuba abathengi banokufumana iimveliso abazifunayo ngexesha xa bezifuna.

3. Izakhono zeR&D

Umthengisi ogqwesileyo uhlala eneqela eliqinileyo le-R&D elinokuthi ngokuqhubekayo liphucule iimveliso kunye nokuphuhlisa iimveliso ezintsha. I-Suzhou Myland iqokelele amava atyebileyo kuphando kunye nokusetyenziswa kweSqualene kwaye iyakwazi ukubonelela abathengi ngenkxaso yobuchwephesha kunye nezisombululo.

4. Inkonzo yabaThengi

Inkonzo elungileyo yabathengi yinto engenakuhoywa xa ukhetha umthengisi. I-Suzhou Myland igxile kunxibelelwano kunye nabathengi kwaye iyakwazi ukubonelela ngeenkonzo zomntu ngokweemfuno zabathengi ukuqinisekisa ukuba abathengi bafumana amava angcono ngexesha lokuthenga.

5. Isiqinisekiso kunye nokuThobela

Ukuqinisekisa ukuba ababoneleli banezatifikethi ezifanelekileyo kunye nokuthotyelwa ziikhrayitheriya ezibalulekileyo zokukhethwa. I-Suzhou Myland yi-ISO eqinisekisiweyo kwaye ihambelana nemigangatho ye-GMP (i-Good Manufacturing Practice), iqinisekisa ukuba iimveliso zayo zilandela inkqubo yokulawula umgangatho ongqongqo ngexesha lenkqubo yokuvelisa.

Ukuququmbela

Ukukhetha umboneleli ofanelekileyo we-Squalene ngundoqo ekuqinisekiseni umgangatho wemveliso kunye nokhuseleko. I-Suzhou Myland iye yaba lukhetho oluthembekileyo kwishishini kunye neemveliso zayo ezicocekileyo, ulawulo olungqongqo lwekhwalithi kunye neenkonzo zobungcali. Nokuba ungumenzi wemveliso yokhathalelo lwesikhumba, inkampani yezithambiso okanye omnye umntu ofuna imveliso, iSuzhou Myland inokukunika umgangatho ophezulu we-Squalene powder ukunceda impilo yakho kunye nophuhliso lomsebenzi. Ukufumana iinkcukacha ezithe vetshe, nceda undwendwele iwebhusayithi esemthethweni ye-Suzhou Mailun Biology.