Salidroside yaziwa nangokuthi (4-hydroxy-phenyl) -β-D-glucopyranoside, eyaziwa ngokuba yi-salidroside kunye ne-rhodiola extract. Inokukhutshwa kwi-Rhodiola rosea okanye i-artificially synthesized. I-Salidroside yi-antioxidant yendalo ekhusela iiseli ze-nerve ngokukhupha i-ROS kunye nokuthintela i-apoptosis yeseli.
I-Rhodiola rosea sisityalo esihlala sihlala sikhula kwiindawo ezinengqele ephezulu, ukoma, i-anoxia, imitha ye-ultraviolet enamandla, kunye nokwahlukana okukhulu kobushushu phakathi kwemini nobusuku kumphakamo we-1,600 ukuya kwi-4,000 yeemitha. Inokuguquguquka okugqithisileyo kokusingqongileyo kunye namandla.
ISalidroside--Antioxidant
I-Salidroside sisisithintelo sendalo esikhuselayo esinokutshabalalisa iintlobo zeoksijini esebenzayo (ROS), inqanda i-apoptosis, kwaye ikhusele iiseli zemithambo-luvo. Inokuphucula amandla okukhusela i-antioxidant yolusu ngokwenza iinkqubo ze-enzyme ye-intracellular antioxidant, ezifana ne-superoxide dismutase (SOD), i-glutathione peroxidase (GSH-Px), njl.
I-Intracellular calcium overload yenye yezona zizathu eziphambili ze-neuronal apoptosis. I-Rhodiola rosea extract kunye ne-salidroside inokunciphisa ukunyuka kwamanqanaba e-calcium yamahhala e-intracellular eyenziwa yi-oxidative stress kunye nokukhusela iiseli ze-cortical zabantu kwi-glutamate. kunye ne-hydrogen peroxide-induced apoptosis. I-Salidroside inokuthintela i-lipopolysaccharide-induced microglial activation, inhibit NO production, inhibit inducible nitric oxide synthase (iNOS) umsebenzi, kunye nokunciphisa i-TNF-α kunye ne-IL-1β. , Amanqanaba e-IL-6.
I-Salidroside inqanda i-NADPH oxidase 2/ROS/mitogen-activated protein kinase (MAPK) kunye nomlawuli wempendulo yophuhliso kunye nomonakalo we-DNA 1 (REDD1)/ithagethi ye-mammalian ye-rapamycin (mTOR)/p70 ribosome Iprotein S6 kinase indlela yomqondiso yenza ukuba kusebenze ukuxhomekeka kwe-AMP protein kinase / silent umlawuli ulwazi 1, RAS homologous gene ilungu losapho I-A/MAPK kunye ne-PI3K/Akt iindlela zokubonisa.
Iinzuzo zeSalidroside
1. Impembelelo yokulawula iindlela ezimbini: I-Rhodiola rosea ihlanganisa zonke izinto ezintle emzimbeni kwaye zineendlela ezimbini zokulawula impembelelo yokwenza ukusilela kunye nokunciphisa ukugqithisa. Ngokulawula imisebenzi ye-nervous system, inkqubo ye-endocrine kunye nenkqubo ye-metabolic, iswekile yegazi, i-lipids yegazi, uxinzelelo lwegazi kunye nemisebenzi ye-cardiovascular and cerebrovascular inokubuyiselwa kumanqanaba aqhelekileyo.
2. Ukulawulwa ngokufanelekileyo kwenkqubo ye-nervous: ukuphelisa ngokufanelekileyo uxinzelelo lwabantu, ukulungelelanisa inkqubo ye-nervous central, ukuphucula ubuthongo kunye nokucaphuka, ukuvuya okanye ukudandatheka; phucula ingqalelo kwaye uphucule inkumbulo. Hlaziya ingqondo, unciphise amazinga eempazamo, uphucule umsebenzi kunye nokufunda kakuhle, kwaye uthintele isifo sika-Alzheimer.
3. Ukulwa nokudinwa: I-Rhodiola rosea inefuthe le-cardiotonic, enokunyusa ixesha lemisebenzi eqhelekileyo yengqondo kunye nomzimba kunye nokwandisa umthamo womthwalo wemithambo yengqondo kunye nezihlunu zomzimba. Inempembelelo ebalulekileyo ekukhuseleni nasekuphatheni i-syndrome yokukhathala kunye nokugcina amandla anamandla kunye namandla ixesha elide.
4. I-Anti-radiation kunye ne-anti-tumor: I-Salidroside inokunyusa ngokufanelekileyo izinga lokuguqulwa kwe-T lymphocytes kunye nomsebenzi we-phagocytes, ukwandisa ukugonywa, ukuthintela ukukhula kwethumba, ukwandisa iiseli zegazi ezimhlophe, ukuxhathisa imitha ye-microwave, kunye nokunyanga izigulane zomhlaza emva kwe-radiotherapy kunye nezinye. Inesiphumo esihle kakhulu sokunceda abo babuthathaka ngokwasemzimbeni emva kokugula.
5. I-Anti-hypoxia: I-Rhodiola rosea inokunciphisa umlinganiselo wokusetyenziswa kweoksijini kumzimba wonke, iphucule ukunyamezela kwengqondo kwi-hypoxia, kwangaxeshanye yandise amandla okuthwala ioksijini egazini, yandise ukuxhathisa kwezifo zomzimba, ize ikhawuleze ibuyise izicwili ezigulayo. .
6. Ifuthe kwisihlunu somntu esigudileyo: Isifuba sibangelwa kukugxadazela kwezihlunu ezigudileyo. I-Rhodiola rosea inokukhulula ngokufanelekileyo i-spasm egudileyo yezihlunu kwaye ilawule intshukumo yamathumbu egudileyo yezihlunu. Ineempembelelo ezicacileyo kwi-asthma, i-bronchitis, i-phlegm, i-constipation, njl.
7. Impembelelo kwi-rheumatoid arthritis: Isifo samathambo sibangelwa bububi obuthathu bomoya, ukubanda, kunye nokufuma. Inani elikhulu lezilingo zeklinikhi libonise ukuba i-Rhodiola rosea inokukhupha umoya, ixhathise ukubanda, kwaye isuse intlungu. Ingakumbi ineempembelelo ezicacileyo ekudumbeni kwamalungu. Ukudumba kunye nesiphumo sokuthintela.
8. Ukuchasana nokuguga: I-Rhodiola rosea inokulibazisa ukuguga kweeseli, ukwandisa umsebenzi we-SOD emzimbeni, kwaye inqanda ukubunjwa kwe-intracellular lipofuscin kunye neentlobo ze-oksijini ezisebenzayo. Ukuphucula i-cell metabolism kunye ne-synthesis kunye nokuphucula amandla eeseli. Ukongeza, nayo inobuhle kunye neziphumo zokhathalelo lwesikhumba.
I-Salidroside kunye neNdawo yokuKhathalela ulusu
Kwintsimi yokunakekelwa kwesikhumba, i-salidroside inokumelana nomonakalo we-ultraviolet kwaye isuse i-radicals yamahhala eveliswa yi-mitochondria. I-antioxidant kunye ne-anti-inflammatory effects inokuphucula imeko yesikhumba, ukunciphisa imibimbi, kwaye yenza ulusu lubukeke luncinci.
I-Rhodiola rosea inokunciphisa umsebenzi we-asidi phosphatase kunye nemveliso yokugqibela yokubola ye-lipid peroxide (LPO) ngokunyusa umsebenzi we-enzymes ehlobene ne-antioxidant (i-SOD superoxide dismutase, i-GSH-Px glutathione peroxidase kunye ne-CAT) umxholo kunye nomxholo we-MDA, ngaloo ndlela uphucula amandla omzimba. ukutshabalalisa iiradicals zasimahla, ukunciphisa inqanaba le-peroxidation ye-biofilms, kunye nokukhusela iiseli zomzimba kunye nezicubu kumonakalo omkhulu wasimahla.
Ukuthintela ukufotowa kwesikhumba
I-Salidroside inokunciphisa ukuthotywa kwe-matrix ye-extracellular efana ne-collagen kwaye ikhuthaze ukukhula kwe-fibroblasts, ngaloo ndlela iphucula ukuqina kolusu, ukulibazisa ukwenzeka kwemibimbi yolusu, kunye nokufezekisa injongo yokuchasa ukufota.
Ukwenza mhlophe
I-Salidroside inokunciphisa i-melanin synthesis ngokuvimbela umsebenzi we-tyrosinase. I-Tyrosinase yi-enzyme ephambili ye-melanin synthesis. I-Salidroside inokubophelela kwi-tyrosinase kwaye inciphise umsebenzi wayo, ngaloo ndlela inciphisa ukuveliswa kwe-melanin.
I-Salidroside inokuthintela ukuhlanganiswa kwe-melanin ngokulawula iindlela zokubonisa kwii-melanocytes, ezifana ne-MITF yokubonisa indlela. I-MITF yinto ephambili yokubhala kwi-melanocytes, elawula ukubonakaliswa kwee-enzymes ezinxulumene ne-melanin ezifana ne-tyrosinase. I-Salidroside inokunciphisa ukubonakaliswa kwe-MITF, ngaloo ndlela inciphisa i-melanin synthesis.
Ukuchasana nokudumba
I-Salidroside inokunciphisa impendulo yokuvuvukala ebangelwa imitha ye-ultraviolet, ukulungisa iiseli zolusu ezonakalisiweyo, kunye nokukhuthaza ukuvuselelwa nokulungiswa kwesikhumba.
Ubume bangoku bokuveliswa kwe-salidroside
1)Kuxhomekeke ikakhulu ekutsalweni kwezityalo
I-Rhodiola rosea yimathiriyeli ekrwada ye-salidroside. Njengohlobo lwesityalo esihlala sikhula, i-Rhodiola rosea ikhula ikakhulu kwiindawo ezinengqele ephezulu, i-anoxia, ukoma kunye nokwahlukana okukhulu kobushushu phakathi kwemini nobusuku kumphakamo we-1600-4000 yeemitha. Sesinye sezityalo ezikumathafa asendle. I-China yenye yezona ndawo zivelisa i-Rhodiola rosea emhlabeni, kodwa iindlela zokuphila ze-Rhodiola rosea zikhethekileyo. Akunzima nje ukulima ngokuzenzela, kodwa isivuno seentlobo zasendle siphantsi kakhulu. Okwangoku, umsantsa wonyaka wemfuno yeRhodiola rosea uphakame kangangeetoni ezingama-2,200.
2) Ukwenziwa kweekhemikhali kunye nokuvutshelwa kwezinto eziphilayo
Ngenxa yomxholo ophantsi kunye neendleko eziphezulu zemveliso kwizityalo, ngaphezu kweendlela zokukhutshwa kwendalo, iindlela zokuvelisa i-salidroside nazo zibandakanya iindlela zokudityaniswa kweekhemikhali, iindlela ze-biological fermentation, njl. indlela yeteknoloji yophando kunye nophuhliso kunye nokuveliswa kwe-salidroside. Okwangoku, i-Suzhou Mailun iphumelele uphando kunye neziphumo zophuhliso kwaye iphumelele ushishino.
Ukusasazeka kwemitha yinxalenye engenakuphepheka kubomi bethu bemihla ngemihla kwaye isetyenziswa rhoqo ekuxilongweni nasekunyangweni kwezonyango. Nangona kunjalo, umonakalo obangelwa yimitha yemitha kwizicubu zomntu kunye neeseli awukwazi ukuhoywa. Ke ngoko, ukufumana iiarhente ezikhuselayo ezisebenza kakuhle, ezinetyhefu esezantsi okanye ezingenayo ityhefu ibisoloko iyindawo yophando.
I-Suzhou Myland Nutraceuticals Inc. ngumvelisi obhalisiwe we-FDA obonelela ngekhwalithi ephezulu kunye nococeko oluphezulu lwe-Salidroside powder.
E-Suzhou Myland sizimisele ukubonelela ngezona mveliso zikumgangatho ophezulu ngamaxabiso angcono. I-powder yethu ye-Salidroside ihlolwe ngokungqongqo ukucoceka kunye namandla, ukuqinisekisa ukuba ufumana isongezelelo somgangatho ophezulu onokumthemba. Nokuba ufuna ukuxhasa impilo yeselula, ukomeleza amajoni akho omzimba okanye ukuphucula impilo yonke, umgubo wethu weSalidroside lolona khetho lufanelekileyo.
Ineminyaka engama-30 yamava kwaye iqhutywa bubuchwepheshe obuphezulu kunye nezicwangciso ze-R&D eziphuculwe kakhulu, iSuzhou Myland iphuhlise uluhlu lweemveliso ezikhuphisanayo kwaye ibe sisongezelelo sesayensi yobomi, ukudibanisa isiko kunye nenkampani yeenkonzo zokuvelisa.
Ukongeza, iSuzhou Myland ikwangumvelisi obhalisiweyo we-FDA. Izixhobo ze-R&D zenkampani, izixhobo zemveliso, kunye nezixhobo zohlalutyo zezanamhlanje kwaye zinemisebenzi emininzi, kwaye zinokuvelisa iikhemikhali ukusuka kwimilligrams ukuya kwiitoni kwisikali, kwaye zithobela imigangatho ye-ISO 9001 kunye neenkcukacha zemveliso ye-GMP.
Ukuziphendulela: Eli nqaku lelolwazi ngokubanzi kuphela kwaye akufanele lithathwe njengeliphi na icebiso lonyango. Olunye ulwazi lweposti yebhlog luvela kwi-Intanethi kwaye alunamsebenzi. Le webhusayithi inoxanduva kuphela lokuhlela, ukufomatha kunye nokuhlela amanqaku. Injongo yokudlulisa ulwazi olongezelelekileyo ayithethi ukuba uyavumelana neembono zayo okanye uqinisekise ubunyani bomxholo wayo. Soloko udibana nengcali yezempilo ngaphambi kokuba usebenzise naziphi na izongezo okanye wenze utshintsho kwirejimeni yokhathalelo lwempilo.
Ixesha lokuposa: Oct-09-2024