Kubantu abaninzi, ukulawula amanqanaba aphezulu e-cholesterol yinkxalabo enkulu. I-cholesterol ephezulu yonyusa umngcipheko wesifo senhliziyo, isifo sohlangothi, kunye nezinye iingxaki zempilo ezinzulu. Nangona ukuguquka kwendlela yokuphila njengokutya kunye nokuzivocavoca kunokunceda ukunciphisa i-cholesterol, ngamanye amaxesha ukungenelela okongezelelweyo kuyafuneka. Olunye ukungenelela okunjalo kukusetyenziswa kwe-niacin, uhlobo lwe-vitamin B3 oluye lwaboniswa ukuba lunefuthe elihle kumanqanaba e-cholesterol. Ifumaneka kwiintlobo ngeentlobo zokutya, kuquka inyama, intlanzi, inkukhu, iipari eziqinisiweyo kunye nezonka. Ukongeza kwindima yayo kwi-metabolism yamandla, i-niacin ibonakaliswe ukuba inefuthe elihle kumanqanaba e-cholesterol.
I-Niacin, ekwabizwa ngokuba yi-vitamin B3, ekwabizwa ngokuba yi-niacin vitamin kunye ne-nicotinamide, yivithamin enyibilikayo emanzini edlala indima ebalulekileyo kwimetabolism yomzimba. Ibalulekile ekuguquleni iicarbohydrates, amafutha kunye neeproteni zibe amandla kwaye ikwanceda nokugcina ulusu olusempilweni, uvalo kunye neenkqubo zokwetyisa.
I-Niacin ifumaneka kwiindidi zokutya, kuquka inyama, intlanzi, amandongomane kunye neenkozo. Inokuthi yenziwe ngumzimba kwi-amino acid tryptophan, nangona le nkqubo ayanelanga ukuhlangabezana neemfuno zemihla ngemihla ze-niacin.
I-Niacin iza ngeendlela ezimbini ezixhaphake ekutyeni nakwizongezo: iniacinamide kunye ne-niacin. Zombini ezi fom ziguqulwa emzimbeni zibe yi-coenzyme esebenzayo ye-niacin, ethi ke isetyenziswe kwiindlela ezahlukeneyo zokuphendula.
I-Niacin iboniswe ukwandisa amanqanaba e-HDL (elungileyo) i-cholesterol ngelixa inciphisa i-LDL (embi) i-cholesterol kunye ne-triglycerides. Oku kuyenza isondlo esibalulekileyo ekugcineni impilo ye-cardiovascular nokunciphisa umngcipheko wesifo senhliziyo.
Ukongeza kwindima yayo kwi-cholesterol metabolism, i-niacin ikwabandakanyeka kulawulo lwamanqanaba eswekile yegazi. Inceda ukuphucula uvakalelo lwe-insulin kunye nokunciphisa ukuvuvukala.
Kubalulekile kwimveliso yeNAD(nicotinamide adenine dinucleotide) kunye ne-NADP (nicotinamide adenine dinucleotide phosphate), eziyi-coenzymes ezibandakanyeka kwiinkqubo ezahlukeneyo zeselula, kubandakanywa ukuveliswa kwamandla kunye nokukhusela i-antioxidant.
Okokuqala, i-niacin ibalulekile kwimpilo yethu yentliziyo. Inceda amanqanaba aphantsi e-LDL, okanye i-cholesterol "embi", ngelixa inyusa amanqanaba e-HDL, okanye i-cholesterol "elungileyo". Oku kunokuba nefuthe elihle kwimpilo yentliziyo yethu kunye nokunciphisa umngcipheko wezifo zentliziyo ezifana nesifo senhliziyo kunye nesifo sohlangothi. Ukongezelela, i-niacin ibonakaliswe ukunciphisa amanqanaba e-triglyceride, ekwalungile kwimpilo yentliziyo yethu.
Ukongezelela, i-niacin idlala indima ephambili kwimveliso yamandla emzimbeni. Ibandakanyeka kwinkqubo yokuguqula iicarbohydrates zibe yiglucose, owona mthombo wamandla kwiiseli zethu. Oku kunceda ukulwa neemvakalelo zokudinwa kunye nokuphucula amanqanaba onke amandla, okwenza i-niacin ibe sisondlo esibalulekileyo sokugcina amandla kunye nokunyamezela.
Enye inzuzo ebalulekileyo ye-niacin yindima yayo ekuxhaseni inkqubo ye-nervous enempilo. Ibandakanyeka kwimveliso ye-neurotransmitters, iikhemikhali ezinceda ukuhambisa imiqondiso phakathi kweeseli ze-nerve. Oku kunokuba nefuthe elihle kwimo yethu, ukusebenza kwengqondo, kunye nempilo yengqondo ngokubanzi.
I-Niacin nayo ineempawu ze-antioxidant ezinceda ukulwa noxinzelelo lwe-oxidative kunye nokunciphisa ukuvuvukala emzimbeni. Oku kunokuba nefuthe elihle kwimpilo yethu yonke kwaye kunokunceda ukunciphisa umngcipheko wezifo ezingapheliyo ezifana nomhlaza kunye nesifo sikashukela. Ukongezelela, i-niacin ibonakaliswe ukuba inefuthe elihle kwimpilo yesikhumba, inceda ukunciphisa ukubonakala kwe-acne kunye nokukhuthaza umbala ocacileyo, ophilileyo.
Ukongezelela, i-niacin ibalulekile ekusebenzeni ngokufanelekileyo kwenkqubo yokugaya. Inceda ukuxhasa ukuveliswa kwee-enzymes zokugaya, eziyimfuneko ekwaphuleni ukutya kunye nokufunxa izondlo. Oku kunokuba nefuthe elihle kwimpilo yethu yonke yokwetyisa kwaye kunokunceda ukuthomalalisa iimpawu ezifana nokuqunjelwa kunye nokuqunjelwa.
Ukongeza kwezi zibonelelo, i-niacin ibonakaliswe ukuba inefuthe elihle kwi-insulin sensitivity, ebalulekileyo ekulawuleni amanqanaba eswekile yegazi kunye nokunciphisa umngcipheko wesifo sikashukela. Ikwadlala indima ekuxhaseni umsebenzi odibeneyo onempilo kwaye inokunceda ukunciphisa iimpawu ze-arthritis kunye nolunye ukuvuvukala.
I-Niacin ithathwa njengento ebalulekileyo yokunceda i-cholesterol ephantsi, kwaye izifundo ezininzi zibonise ukuba i-niacin inokunciphisa ngokufanelekileyo amanqanaba e-cholesterol ye-LDL, eyaziwa ngokuba yi-cholesterol "embi". Kwakhona kubonakaliswe ukwandisa amanqanaba e-HDL cholesterol (ehlala ebizwa ngokuba yi-cholesterol "elungileyo"). Kodwa i-niacin ifikelela njani kwezi ziphumo?
Enye yeendlela iniacin enceda ngayo ukwehlisa i-cholesterol kukuthintela ukuveliswa kwesibindi se-lipoprotein cholesterol, isandulela se-low-density lipoprotein cholesterol. Oku kuthetha ukuba isibindi sivelisa i-cholesterol encinci ye-LDL, ekhokelela kumanqanaba asezantsi e-LDL cholesterol egazini. I-Niacin ikwanceda ukwandisa umsebenzi we-lipoprotein lipase, i-enzyme enceda ukuphula i-triglycerides (olunye uhlobo lwamafutha egazini). I-Niacin inciphisa ngokungangqalanga amanqanaba e-cholesterol ye-LDL ngokunciphisa i-VLDL kunye namanqanaba e-triglyceride.
I-Niacin inokunyusa amanqanaba e-cholesterol ye-HDL. Icholesterol yeHDL inceda ekususeni iLDL cholesterol egazini, iyise esibindini apho inokwaphulwa khona ize ipheliswe emzimbeni. Kungenxa yoko le nto i-cholesterol ye-HDL idla ngokubizwa ngokuba yi-cholesterol "elungileyo" kuba inceda ukukhusela i-plaque kwi-artery, enokukhokelela kwisifo senhliziyo.
Ukongeza kwimiphumo yayo kumanqanaba e-cholesterol, i-niacin ifunyenwe inezinye izibonelelo zentliziyo. Inokukunceda ukunciphisa ukuvuvukala kwimibhobho, into ebalulekileyo ekuphuhliseni i-atherosclerosis, okanye ukuqina kwemithambo. I-Niacin nayo ibonakaliswe ekuphuculeni umsebenzi weeseli ze-endothelial (i-lining of blood vessels), inceda ukuphucula ukuhamba kwegazi kunye nokunciphisa umngcipheko we-blood clots. Ukongeza, i-niacin inokulinganisa amanqanaba eswekile yegazi kwaye incede ukulawula isifo seswekile.
I-Niacin, ekwabizwa ngokuba yi-vitamin B3, sisondlo esibalulekileyo. Kubalulekile kwimisebenzi eyahlukeneyo yomzimba, kubandakanywa imetabolism, umsebenzi we-nerve, kunye nokuveliswa kwamandla eselula. Ukufaka ukutya okutyebileyo kwe-niacin ekutyeni kwakho kulula kuba kukho iintlobo ngeentlobo zokutya okuqulethe izixa ezikhulu zesi sondlo sibalulekileyo. Okunye ukutya okutyebileyo kwi-niacin kubandakanya:
1. Inkukhu
Inkukhu ngumthombo omkhulu we-niacin kunye neprotheni ephilileyo. Ingaba ukhetha inkukhu eyosiweyo, ebhakiweyo, okanye eyosiweyo, ukubandakanya le nyama enqabileyo kwisidlo sakho yindlela efanelekileyo yokwandisa i-niacin yakho.
2. Ituna
ityhuna ayiphelelanga nje ekubeni ngumthombo omkhulu we-niacin, kodwa ikwatyebile kwi-Omega-3 fatty acids, ezibalulekileyo kwimpilo yentliziyo. Ukongeza ityhuna kwiisaladi, iisandwich, okanye i-sushi rolls yindlela elumkileyo yokwandisa ukutya kwakho kwe-niacin.
3. Amandongomane
Amandongomane sisishwamshwam esimnandi kwaye esiluncedo esityebileyo kwiniacin. Nokuba ukhetha amandongomane kwimo ekrwada, egcadiweyo okanye ibhotolo yamandongomane, ukongeza amandongomane ekutyeni kwakho yindlela elula yokufumana i-niacin eninzi.
4. Amakhowa
Akunjalo kuphela amakhowa angumthombo omkhulu we-niacin, aphantsi kweekhalori kwaye aphakamileyo kwi-antioxidants. Ukongeza amakhowa kwiisuphu, isaladi, okanye i-stir-fries yindlela enhle yokufumana i-niacin eninzi ekutyeni kwakho.
5. Iimbotyi eziluhlaza
Akunjalo kuphela ii-peas eziluhlaza zingumthombo olungileyo we-niacin, kodwa zityebile kwifiber, iprotheni, kunye nezinye iivithamini eziyimfuneko kunye neeminerali. Ukongeza ii-peas eziluhlaza ekutyeni kwakho yindlela efanelekileyo yokwandisa i-niacin yakho yokutya ngelixa unyusa umthamo wakho wezondlo.
6. Imbewu yejongilanga
Imbewu kajongilanga yi-snack exineneyo yezondlo egcwele i-niacin, i-vitamin E, i-magnesium kunye nezinye izondlo ezibalulekileyo. Ukutya imbewu yejongilanga phakathi kokutya yindlela efanelekileyo yokwandisa i-niacin yakho yokutya ngelixa usanelisa indlala.
Ukongeza koku kutya okutyebileyo kwe-niacin, kukho eminye imithombo emininzi ye-niacin onokuthi udibanise ekudleni kwakho, njenge-salmon, i-avocados kunye neenkozo ezipheleleyo. Ngokubandakanya iintlobo ezahlukeneyo zoku kutya kwisidlo sakho kunye nokutya, unokuqinisekisa ukuba ufumana izixa ezaneleyo ze-niacin ukuxhasa impilo yakho yonke kunye nokuphila kakuhle.
I-Niacin, ekwabizwa ngokuba yi-vitamin B3, sisondlo esibalulekileyo esidlala indima ebalulekileyo ekugcineni impilo. Ibandakanyeka kwiinkqubo ezahlukeneyo zomzimba, kubandakanywa imetabolism, ukulungiswa kwe-DNA, kunye ne-hormone synthesis. Nangona i-niacin yenzeka ngokwemvelo kukutya okuninzi, abanye abantu banokufuna izongezo ezongezelelweyo ukuhlangabezana neemfuno zabo zemihla ngemihla.
Xa ucinga ngokuthatha izongezo ze-niacin, kubalulekile ukwenza ukhetho olunolwazi ngempilo yakho. Kukho izinto ezininzi ezibalulekileyo ekufuneka uziqwalasele xa usenza isigqibo sokuba izongezo ze-niacin zikulungele na
Okokuqala, kubalulekile ukuqonda iingenelo ezinokubakho ze-niacin supplementation. I-Niacin ifundwe ngamandla ayo okuphucula amanqanaba e-cholesterol, ukunciphisa umngcipheko wesifo senhliziyo, kunye nokuphucula ukusebenza kwengqondo. Ukongezelela, i-niacin ineempawu ezichasayo ezinokuthi zincede ukunciphisa umngcipheko wezifo ezithile ezingapheliyo.
Nangona kunjalo, kubalulekile ukuqwalasela imingcipheko enokubakho kunye nemiphumo emibi ye-niacin supplementation, kwaye kubalulekile ukuxoxa ngesicwangciso sakho sokuthatha izongezelelo ze-niacin kunye nomboneleli wakho wezempilo ukuqinisekisa ukuba kukhuselekile kwaye kulungile kuwe.
Ukongeza, kubalulekile ukukhetha isongezelelo somgangatho ophezulu we-niacin kumthombo othembekileyo. Ayizizo zonke izongezo ezenziwe ngokulinganayo, ngoko ke kubalulekile ukukhetha imveliso esemgangathweni evela kuhlobo oluthembekileyo, kukhethwa ukuba kuveliswe kwiziko elithobela imigangatho engqongqo yolawulo lomgangatho. Ukongeza, unokufuna ukuqwalasela ukukhangela izongezo eziye zavavanywa ngumntu wesithathu, njengoko oku kuqinisekisa ukuba amandla kunye nokucoceka kwemveliso kuye kwaqinisekiswa ngokuzimeleyo. Oku kunokunceda ukuqinisekisa ukuba ufumana imveliso ekhuselekileyo nesebenzayo.
Xa ukhetha isongezelelo se-niacin, kubalulekile ukuqwalasela uhlobo lwe-niacin olusetyenziswe kwi-supplement.
1. I-Niacin: Le yeyona ndlela ixhaphakileyo ye-niacin efumaneka kwizongezelelo. Iyaziwa ngokukwazi kwayo ukuxhasa impilo ye-cardiovascular ngokunceda ukunciphisa amanqanaba e-cholesterol kunye nokuphucula ukujikeleza kwegazi. Nangona kunjalo, abanye abantu banokufumana ukugungxulwa kwesikhumba okanye ububomvu bexeshana njengesiphumo sokuthatha i-niacin.
2. I-Niacinamide: Ikwaziwa njenge-niacinamide, olu hlobo lwe-niacin ludumile ngenxa yeenzuzo zayo ezinokuthi zibe kho kulusu. Ihlala isetyenziswa kwiimveliso zokunakekelwa kwesikhumba ukunceda ukuphucula ukubonakala kwemigca emihle, imibimbi kunye ne-acne. I-Niacinamide ikwaluncedo ekuxhaseni umsebenzi womzimba wonke kunye nempilo yengqondo.
3. Inositol hexanicotinate: Le yindibaniselwano ye-niacin kunye ne-myo-inositol, utywala obushukela. I-Inositol hexanicotinate isetyenziswa ngokuqhelekileyo ukuxhasa inkqubo yokujikeleza okunempilo kwaye inokunceda ukugcina amanqanaba e-cholesterol enempilo.
I-Suzhou Myland Pharm & Nutrition Inc. uzibandakanye kwishishini lokongezelela isondlo ukusukela ngo-1992. Yinkampani yokuqala e-China ukuphuhlisa nokuthengisa isicatshulwa sembewu yomdiliya.
Iminyaka engama-30 yamava kwaye iqhutywa bubuchwephesha obuphezulu kunye nesicwangciso se-R&D esiphuculwe kakhulu, inkampani iphuhlise uluhlu lweemveliso ezikhuphisanayo kwaye ibe sisongezelelo sesayensi yobomi, ukuhlanganiswa kwesiko kunye nenkampani yeenkonzo zokuvelisa.
Ukongeza, inkampani ikwangumvelisi obhalisiweyo we-FDA, eqinisekisa impilo yabantu enomgangatho ozinzileyo kunye nokukhula okuzinzileyo. Izibonelelo ze-R&D zenkampani kunye nezixhobo zemveliso kunye nezixhobo zohlalutyo zezanamhlanje kwaye zinemisebenzi emininzi, kwaye ziyakwazi ukuvelisa iikhemikhali kwi-milligram ukuya kwisikali seetoni ngokuthobela imigangatho ye-ISO 9001 kunye neendlela zokuvelisa ze-GMP.
Umbuzo: Yintoni i-niacin kwaye isebenza njani ukunciphisa amanqanaba e-cholesterol?
A: I-Niacin, eyaziwa ngokuba yi-vitamin B3, i-vitamin e-soluble yamanzi ebonakaliswe ukunciphisa i-LDL (embi) i-cholesterol kunye namanqanaba e-triglyceride ngelixa inyusa amanqanaba e-cholesterol ye-HDL (elungileyo). Isebenza ngokuthintela ukuveliswa kwesibindi se-cholesterol kunye ne-triglycerides.
Umbuzo: Ngaba i-niacin iyasebenza ekunciphiseni amanqanaba e-cholesterol?
A: Ewe, i-niacin ibonakaliswe ukuba iyasebenza ekwehliseni amanqanaba e-cholesterol, ngakumbi i-cholesterol ye-LDL kunye ne-triglycerides. Inokunyusa amanqanaba e-cholesterol ye-HDL, eyinzuzo kwimpilo yentliziyo.
Umbuzo: Ingakanani i-niacin ekufuneka ithathwe ukunciphisa amanqanaba e-cholesterol?
A: Idosi efanelekileyo ye-niacin yokunciphisa amanqanaba e-cholesterol iyahluka ngokuxhomekeke kwizinto ezinjengobudala, isini, kunye nempilo yonke. Kubalulekile ukusebenzisana nengcali yezempilo ukumisela idosi efanelekileyo kuwe.
Ukuziphendulela: Eli nqaku lelolwazi ngokubanzi kuphela kwaye akufanele lithathwe njengeliphi na icebiso lonyango. Olunye ulwazi lweposti yebhlog luvela kwi-Intanethi kwaye alunamsebenzi. Le webhusayithi inoxanduva kuphela lokuhlela, ukufomatha kunye nokuhlela amanqaku. Injongo yokudlulisa ulwazi olongezelelekileyo ayithethi ukuba uyavumelana neembono zayo okanye uqinisekise ubunyani bomxholo wayo. Soloko udibana nengcali yezempilo ngaphambi kokuba usebenzise naziphi na izongezo okanye wenze utshintsho kwirejimeni yokhathalelo lwempilo.
Ixesha lokuposa: Jan-02-2024