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Ukukhuthaza iMpilo yoBuchule ngokuTshintsha indlela yokuphila yoThintelo lwe-Alzheimer

Isifo sika-Alzheimer sisifo sobuchopho esichaphazela izigidi zabantu kwihlabathi jikelele.Ekubeni okwangoku akukho unyango lwesi sifo sitshabalalisayo, ugxininiso kuthintelo lubalulekile.Nangona i-genetics idlala indima ekuphuhliseni isifo se-Alzheimer, uphando lwakutsha nje lubonisa ukuba utshintsho lwendlela yokuphila lunokunciphisa kakhulu umngcipheko wokuphuhlisa isifo.Ukukhuthaza impilo yengqondo ngeendlela ezahlukeneyo zokuphila kunokuhamba indlela ende ekuthinteleni isifo sika-Alzheimer.

Ukuqonda iSiseko: Yintoni isifo sika-Alzheimer?

Isifo sika-Alzheimer sisifo semithambo-luvo esinenkqubela echaphazela izigidi zabantu kwihlabathi jikelele.

Okokuqala kufunyenwe kwi-1906 ngugqirha waseJamani u-Alois Alzheimer, le meko ephazamisayo yenzeke ngokuyinhloko kubantu abadala kwaye iyona nto ibangela ukuba i-dementia ixhaphake.I-dementia ligama elibhekiselele kwiimpawu zokuncipha kwengqondo, ezinjengokulahleka kokucinga, inkumbulo, kunye nobuchule bokuqiqa.Abantu ngamanye amaxesha babhidanisa isifo sika-Alzheimer kunye nesifo sengqondo esiyingozi.

Ukuqonda iSiseko: Yintoni isifo sika-Alzheimer?

Isifo sika-Alzheimer siphazamisa ngokuthe ngcembe ukusebenza kwengqondo, sichaphazela inkumbulo, ukucinga kunye nokuziphatha.Ekuqaleni, abantu basenokulibala yaye babhideke kancinane, kodwa njengoko esi sifo sihambela phambili, sisenokuphazamisana nemisebenzi yemihla ngemihla size sitshabalalise namandla okubamba incoko.

Iimpawu zesifo sika-Alzheimer ziya ziba mandundu ngokuhamba kwexesha kwaye zinokuchaphazela kakhulu umgangatho wobomi bomntu.Ukulahlekelwa yinkumbulo, ukubhideka, ukudideka kunye nobunzima bokusombulula iingxaki ziimpawu eziqhelekileyo zakwangoko.Njengoko esi sifo siqhubela phambili, abantu banokuba nokuguquka kwemizwelo, utshintsho lobuntu, nokurhoxa kwimisebenzi yentlalo.Ekuhambeni kwexesha, basenokufuna uncedo kwimisebenzi yemihla ngemihla enjengokuhlamba, ukunxiba nokutya.

Ukuqonda isifo se-Alzheimer: Iimbangela, iimpawu, kunye neMingcipheko yoMngcipheko

Oonobangela

Isifo sika-Alzheimer sisifo se-neurodeergenerative, nto leyo ethetha ukuba yenza umonakalo kwiiseli zemithambo-luvo.Utshintsho kwi-neurons kunye nokulahlekelwa koqhagamshelwano phakathi kwabo kunokukhokelela kwi-brain atrophy kunye nokuvuvukala.

Uphando lubonisa ukuba ukuqokelelana kweeproteni ezithile ebuchotsheni, njengee-beta-amyloid plaques kunye ne-tau tangles, zidlala indima ebalulekileyo ekukhuleni kwesi sifo.

Phakathi kwazo, iinguqu ezimbini zebhayoloji kwingqondo, i-amyloid plaques kunye ne-tau protein tangles, zingundoqo ekuqondeni isifo se-Alzheimer.IBeta-amyloid liqhekeza leprotheyini enkulu.Nje ukuba la maqhekeza adityaniswe abe yi-clumps, abonakala enetyhefu kwi-neuron, ephazamisa unxibelelwano phakathi kweeseli zengqondo.Iprotheyini yeTau idlala indima kwinkxaso yangaphakathi kunye neenkqubo zothutho zeeseli zengqondo, ezithwele izondlo kunye nezinye izinto ezibalulekileyo.I-tau tangles yenzeka xa iimolekyuli ze-tau zinamathelana ngokungaqhelekanga kwaye zenze ukubhityana ngaphakathi kwemithambo-luvo.

Ukubunjwa kwezi proteni ezingaqhelekanga kuphazamisa umsebenzi oqhelekileyo we-neurons, obangela ukuba ngokuthe ngcembe bawohloke kwaye ekugqibeleni bafe.

Oyena nobangela wesifo sika-Alzheimer awaziwa, kodwa indibaniselwano yemfuza, indlela yokuphila kunye nezinto ezisingqongileyo kukholelwa ukuba zinegalelo ekuphuhlisweni kwayo.

Oonobangela

Iimpawu

Iingxaki zenkumbulo zidla ngokuvela kuqala kwisifo sika-Alzheimer.Ngokuhamba kwexesha, abantu basenokungakwazi ukukhumbula iincoko, amagama, okanye iziganeko zamva nje, nto leyo enokukhokelela ekubeni kukhubazeke ngokuthe ngcembe inkumbulo, ukucinga nokuziphatha.

Ezinye iimpawu ziquka:

●Ukulahleka kwememori kunye nokudideka

●Ubunzima ekusombululeni iingxaki nasekuthatheni izigqibo

●Ukuncipha kobuchule bolwimi

●Ilahlekile ngexesha kunye nendawo

●Ukutshintsha kweemvakalelo nokutshintsha kobuntu

●Izakhono zeemoto kunye nemingeni yokulungelelanisa

●Ukutshintsha kobuntu, njengokunyuka kokungxama kunye nobundlongondlongo

Imiba yoMngcipheko

Umngcipheko wokuphuhlisa esi sifo ukhula ngokukhula.Uninzi lwabantu abanesifo i-Alzheimer's baneminyaka engama-65 okanye ngaphezulu, kodwa i-Alzheimer's yangethuba inokubakho nakubantu abancinci abaneminyaka engama-40 okanye engama-50 ubudala.Njengoko abantu bekhula, ubuchopho babo bufumana utshintsho lwendalo olubenza babe sesichengeni sezifo eziwohlokayo ezifana ne-Alzheimer's.

Ukongezelela, abaphandi baye bachonga imizila yemfuza eyandisa umngcipheko wokuba nesifo.I-gene ixhaphake kakhulu ibizwa ngokuba yi-apolipoprotein E (APOE).Wonke umntu ufumana ikopi enye ye-APOE kumzali, kwaye iintlobo ezithile zale jini, njenge-APOE ε4, zonyusa umngcipheko wesifo i-Alzheimer's.Nangona kunjalo, ukuba nolu tshintsho lwemfuza akuthethi ukuba umntu uya kuba nesifo.

Indlela yokuphila inokuba negalelo kwisifo sika-Alzheimer.Impilo engalunganga ye-cardiovascular, kubandakanywa neemeko ezifana noxinzelelo lwegazi oluphezulu, i-cholesterol ephezulu kunye nesifo sikashukela, idibaniswe nomngcipheko okhulayo we-Alzheimer's disease.Indlela yokuphila yokuhlala phantsi, ukutshaya kunye nokutyeba kukwanxulunyaniswa nomngcipheko ophezulu wesifo.

Ukudumba okungapheliyo ebuchotsheni kucingelwa ukuba ngomnye unobangela wesifo i-Alzheimer's.Amajoni omzimba asabela kukwenzakala okanye usulelo ngokukhupha iikhemikhali ezikhuthaza ukudumba.Ngelixa ukudumba kuyimfuneko kwiindlela zokukhusela umzimba, ukudumba okungapheliyo kunokukhokelela kumonakalo wobuchopho.Lo monakalo, kunye nokuqokelelana kwamacwecwe eprotini ebizwa ngokuba yi-beta-amyloid, uphazamisa unxibelelwano phakathi kweeseli zengqondo kwaye kucingelwa ukuba udlala indima ebalulekileyo ekukhuleni kwe-Alzheimer's.

Ukuqonda isifo se-Alzheimer: Iimbangela, iimpawu, kunye neMingcipheko yoMngcipheko

Ungasikhusela njani isifo sika-Alzheimer?

Phucula indlela ophila ngayo kuthintelo lwe-Alzheimer.

●Lawula uxinzelelo lwegazi oluphezulu: Uxinzelelo lwegazi oluphezulu lunokuba neziphumo eziyingozi kwiindawo ezininzi zomzimba, kuquka nengqondo.Imithambo yegazi kunye nentliziyo yakho nazo ziya kuzuza ngokubeka iliso kunye nokulawula uxinzelelo lwegazi.

●Lawula iswekile yegazi (iswekile): Ukuzingisa kweswekile yegazi kwandisa umngcipheko wezifo ezahlukeneyo kunye neemeko, kuquka inkumbulo, ukufunda, kunye neengxaki zengqwalasela.

●Gcina ubunzima obunempilo: Ukutyeba ngokugqithiseleyo kudibaniswa nesifo senhliziyo, isifo sikashukela, kunye nezinye iimeko.Into engekacaci okwangoku yeyona ndlela yokulinganisa ukutyeba.Izifundo ezininzi zibonise ukuba umyinge wesinqe esinqeni ukuya kubude bunokuba sesinye sezona ziqikelelo zichanekileyo zesifo esinxulumene nokutyeba kakhulu.

●Landela ukutya okunempilo: Gxininisa ukutya okunokulinganisela okucebileyo kwiziqhamo, imifuno, ukutya okuziinkozo, iiprotheni ezibhityileyo kunye namafutha anempilo.Ukukhetha ukutya okutyebileyo kwi-antioxidants, njengamajikijolo, imifuno eluhlaza, kunye namantongomane, kunokunceda ukulwa noxinzelelo lwe-oxidative kunye nokuvuvukala okuhambelana nokuncipha kwengqondo.

●Yiba namandla ngokwasemzimbeni: Umsebenzi oqhelekileyo womzimba ubonakaliswe ngokuphindaphindiweyo ukuba udibene neenzuzo ezininzi zempilo, kubandakanywa ukuphuculwa komsebenzi wokuqonda kunye nokunciphisa ingozi yesifo se-Alzheimer.Ukwenza umthambo, njengokuhamba ngokukhawuleza, ukubaleka, ukuqubha, okanye ukukhwela ibhayisekile, kunokunceda ukwandisa ukuhamba kwegazi ebuchotsheni, kukhuthaze ukukhula kweeseli zemithambo-luvo, kuze kunciphise ukwakheka kweeproteni eziyingozi ezinxulumene nesifo sika-Alzheimer.

●Ukulala okusemgangathweni: Ukulala kubaluleke kakhulu emizimbeni nasezingqondweni zethu.Ukungalali kakuhle, kubandakanywa nokungonelanga okanye ukuphazamiseka kokulala, kunxulunyaniswa nomngcipheko okhulayo we-Alzheimer's disease.

●Nciphisa ukusetyenziswa kotywala: Ukusela utywala kakhulu kunokubangela ukuwa kunye nokwenza ezinye iimeko zempilo zibe mandundu, kuquka ukulahlekelwa yinkumbulo.Ukunciphisa ukusela kwakho kwisiselo esinye okanye ezibini ngosuku (ubuninzi) kunokunceda.

●Musa ukutshaya: Ukungatshayi kunokuyiphucula impilo yakho ngokunciphisa amathuba okuba nezigulo ezimandundu ezifana nesifo sentliziyo, isifo sohlangothi, kunye neminye imihlaza.Kananjalo awukho amathuba okuba ube nesifo sika-Alzheimer.

●Gcina isimo sengqondo esinempilo: Ukuba ishiywe ingaqwalaselwanga, uxinzelelo olungapheliyo, ukudakumba kunye nokuxhalaba kunokuchaphazela kakubi impilo yengqondo.Beka phambili impilo yakho yeemvakalelo ukunciphisa umngcipheko wokuhla kwengqondo.Zibandakanye kwiindlela zokulawula uxinzelelo ezifana nokuzivocavoca kwengqondo, ukuphefumla ngokunzulu, okanye i-yoga.

Phucula indlela ophila ngayo kuthintelo lwe-Alzheimer.

Izongezo zokutya kunye ne-Alzheimer's Disease

Ukongeza ekuthinteleni isifo sika-Alzheimer ngotshintsho lwendlela yokuphila, unokongeza ezinye izongezo zokutya kubomi bakho bemihla ngemihla.

1. ICoenzyme Q10

Amanqanaba e-Coenzyme Q10 ayancipha njengoko sikhula, kwaye ezinye izifundo zibonisa ukuba ukuncedisa nge-CoQ10 kunokunciphisa ukuqhubeka kwesifo se-Alzheimer.

2. I-Curcumin

I-Curcumin, i-compound esebenzayo efunyenwe kwi-turmeric, sele isaziwa ixesha elide ngenxa ye-antioxidant enamandla kunye ne-anti-inflammatory properties.Ukongeza, i-astaxanthin ikwayi-antioxidant enamandla enokuthintela ukuveliswa kweeradicals zasimahla kunye nokukhusela iiseli kumonakalo we-oxidative.Ukunciphisa i-cholesterol egazini kunye nokunciphisa ukuqokelela kwe-oxidized low-density lipoprotein (LDL).Uphando olutshanje lubonisa ukuba i-curcumin inokuthintela ukuqala kwesifo se-Alzheimer ngokunciphisa i-beta-amyloid plaques kunye ne-neurofibrillary tangles, eziyimpawu zesifo.

3. IVithamin E

IVithamin E yivithamin enyibilikayo ngamanqatha kunye ne-antioxidant enamandla eye yaphononongwa ngeempawu zayo ezinokuthi zikhuseleke kwisifo se-Alzheimer's.Uphando lubonisa ukuba abantu abanokutya okuphezulu kwivithamin E banomngcipheko ophantsi wokuba nesifo se-Alzheimer okanye ukwehla kwengqondo.Ukubandakanya ukutya okutyebileyo kwe-vitamin E ekutyeni kwakho, okunje ngamandongomane, imbewu, kunye neecereals eziqinisiweyo, okanye ukuthatha izongezelelo ze-vitamin E kunokunceda ukugcina umsebenzi wokuqonda njengoko ukhula.

4. Iivithamini B: Nika amandla kwingqondo

Iivithamini ze-B, ngakumbi i-B6, i-B12, kunye ne-folate, ziyimfuneko kwimisebenzi emininzi yobuchopho, kuquka i-neurotransmitter synthesis kunye nokulungiswa kwe-DNA.Olunye uphononongo lucebisa ukuba ukuthathwa okuphezulu kweevithamini ze-B kunokucothisa ukuhla kwengqondo, kunciphise ukuncipha kwengqondo, kunye nokunciphisa umngcipheko wesifo i-Alzheimer's.Yandisa ukutya kwakho kwe-niacin, ivithamin B esetyenziswa ngumzimba wakho ukuguqula ukutya kube ngamandla.Ikwanceda ukugcina inkqubo yakho yokwetyisa, inkqubo yemithambo-luvo, ulusu, iinwele kunye namehlo esempilweni.

Ngokubanzi, akukho mntu uthembisa ukuba ukwenza nayiphi na kwezi zinto kuya kuthintela i-Alzheimer's.Kodwa sisenokukwazi ukunciphisa umngcipheko wokuba nesifo sika-Alzheimer ngokunikela ingqalelo kwindlela esiphila ngayo nakwindlela esiziphatha ngayo.Ukwenza umthambo rhoqo, ukutya ukutya okunempilo, ukuhlala engqondweni nasentlalweni, ukulala ngokwaneleyo, nokulawula uxinzelelo zizinto ezingundoqo ekuthinteleni isifo sika-Alzheimer.Ngokwenza olu tshintsho lwendlela yokuphila, amathuba okuba nesifo sika-Alzheimer ayancipha kwaye sinokuba nomzimba osempilweni.

Q: Yiyiphi indima edlalwa umgangatho wokulala kwimpilo yengqondo?
A: Ukulala okusemgangathweni kubalulekile kwimpilo yengqondo njengoko ivumela ingqondo ukuba iphumle, ihlanganise iinkumbulo, kunye ne-toxins ecacileyo.Ukungalali kakuhle okanye ukuphazamiseka kokulala kunokunyusa umngcipheko wokuba nesifo i-Alzheimer kunye nezinye iziphazamiso zengqondo.

Umbuzo: Ngaba utshintsho lwendlela yokuphila lulodwa luqinisekisa ukuthintelwa kwesifo sika-Alzheimer?
IMPENDULO: Nangona utshintsho lwendlela yokuphila lunokunciphisa kakhulu umngcipheko wesifo i-Alzheimer, aluqinisekisi ngothintelo olupheleleyo.Imfuza nezinye izinto zisenokudlala indima ekukhuleni kwesi sifo.Nangona kunjalo, ukwamkela indlela yokuphila enempilo yengqondo kunokufaka isandla kwimpilo yengqondo ngokubanzi kunye nokulibazisa ukuqala kweempawu.

Ukuziphendulela: Eli nqaku lelolwazi ngokubanzi kuphela kwaye akufanele lithathwe njengeliphi na icebiso lonyango.Olunye ulwazi lweposti yebhlog luvela kwi-Intanethi kwaye alunamsebenzi.Le webhusayithi inoxanduva kuphela lokuhlela, ukufomatha kunye nokuhlela amanqaku.Injongo yokudlulisa ulwazi olongezelelekileyo ayithethi ukuba uyavumelana neembono zayo okanye uqinisekise ubunyani bomxholo wayo.Soloko udibana nengcali yezempilo ngaphambi kokuba usebenzise naziphi na izongezo okanye wenze utshintsho kwirejimeni yokhathalelo lwempilo.

Ixesha lokuposa: Sep-18-2023