Okwangoku, kukho izongezo ezingenakubalwa kwimarike, nganye ithembisa ukuphucula impilo yakho ngandlela thile. Ngeenketho ezininzi onokukhetha kuzo, ukufumanisa ukuba yeyiphi isongezelelo esilungele iinjongo zakho ezithile zempilo kunokuba nzima. Ukuba ukuphucula impilo yakho iyonke yeyona nto uyixhalabeleyo, ngoko unokufuna ukucinga ngokungongeza isongezelelo se-deazaflavin kwindlela yakho yemihla ngemihla. I-Deazaflavin iyikhompawundi yendalo ebonakaliswe ukuba ineenzuzo ezininzi zempilo, kubandakanywa nokuphucula impilo ye-cardiovascular, ukwandisa amanqanaba amandla, kunye nokuxhasa impilo yonke.
Deazaflavin, ekwaziwa ngokuba yi-5-deazaflavin, inokwakheka okufanayo neflavin, kodwa ubume bayo bemichiza butshintshile xa kuthelekiswa neflavin eqhelekileyo. Olu hlengahlengiso lubandakanya ukususwa kwe-athomu yenitrogen kwiringi yeflavin, okukhokelela kwi-"denitrified" (ithetha "i-nitrogen-deficient") i-molecule ye-flavin. Olu tshintsho lunika i-deazaflavin iipropati zeekhemikhali ezizodwa eziyahlula kwezinye iiflavin. Uphononongo lubonise ukuba i-5-deazaflavin inokuvelisa i-radicals yamahhala ye-5-deazaflavin esebenzayo kakhulu, ephantsi-enokubakho xa kukho ukukhanya kunye nabanikezeli be-electron (ezifana ne-alcohols, i-amines, njl.).
Enye yeyona deazaflavin yaziwa kakhulu yiriboflavin (ivithamin B2), isondlo esibalulekileyo esidlala indima ebalulekileyo ekuveliseni amandla omzimba kunye nemetabolism. I-Riboflavin yi-precursor ye-coenzyme i-flavin mononucleotide (i-FMN) kunye ne-flavin adenine dinucleotide (i-FAD), ethatha inxaxheba kwiimpendulo ezahlukeneyo ze-enzymatic, ngakumbi ikhonkco lokuthutha i-electron yokuphefumla kweselula. Ke ngoko, i-riboflavin kunye nezinto eziphuma kuyo zibalulekile ekugcineni impilo kunye namandla.
Izongezelelo ze-Deazaflavin zixutywe kunye ne-antioxidant kunye ne-anti-inflammatory properties, zibenza zibe yinto ekhuthazayo yokuxhasa impilo yonke kunye nokuphila kakuhle. Ezi zongezo zicingelwa ukuba zinceda ukunyusa amanqanaba amandla, ukuxhasa imetabolism enempilo, kunye nokukhuthaza impilo yentliziyo.
Enye yeenzuzo eziphambili zezongezelelo ze-deazaflavin kukukwazi ukulwa noxinzelelo lwe-oxidative emzimbeni. Uxinzelelo lwe-oxidative lwenzeka xa kukho ukungalingani phakathi kwe-radicals yamahhala kunye ne-antioxidants emzimbeni, kubangela umonakalo kwiiseli kunye nezicubu.
I-Deazaflavins ludidi lweekhompawundi ngokwesakhiwo ezinxulumene ne-riboflavin (ekwaziwa ngokuba yi-vitamin B2). Ezi khompawundi zidlala indima ebalulekileyo kwiinkqubo ezahlukeneyo zemetabolism, kubandakanywa ukuveliswa kwe-adenosine triphosphate (ATP), owona mthombo wamandla weseli. Kukholelwa ukuba izongezo ze-deazaflavin ziphucula imveliso ye-ATP ngokuxhasa umsebenzi wee-enzyme eziphambili ezibandakanyekayo kwimetabolism yamandla.
Izongezelelo ze-Deazaflavins zinamandla okuphucula umsebenzi we-mitochondrial. I-Mitochondria yindlu yamandla yeseli kwaye inoxanduva lokuvelisa i-ATP ngenkqubo ye-phosphorylation ye-oxidative. I-Deazaflavin ibonakaliswe ukwandisa ukusebenza kakuhle kwale nkqubo, ngaloo ndlela yandisa imveliso yamandla kunye nokuphucula ukusebenza kweeseli. I-Deazaflavin icingelwa ukuba ikhuphe i-radicals yamahhala kunye nokunciphisa umonakalo we-oxidative, ngaloo ndlela ikhuthaza ukuguga okunempilo kunye nokunciphisa umngcipheko wezifo ezinxulumene neminyaka.
Ukongezelela, izongezelelo ze-deazaflavin zifunyenwe ukulungelelanisa umsebenzi we-sirtuins, intsapho yeeprotheni ezibandakanyekayo ekulawuleni i-metabolism yeselula, ukulungiswa kwe-DNA, kunye neempendulo zoxinzelelo. I-Sirtuins iyaziwa ukuba idlala indima ephambili kwinkqubo yokuguga kwaye umsebenzi wabo unokuchaphazeleka kwiindidi ezahlukeneyo, kuquka i-deazaflavin. Ngokusebenzisa i-sirtuin enzymes, izongezo ze-deazaflavin zinokukhuthaza ubomi obude kunye nempilo yonke.
I-Deazalavin, ekwaziwa ngokuba yi-riboflavin 5-deazaflavin, luhlobo lwevithamin B2 eyimfuneko ekugcineni impilo yonke. Idlala indima ebalulekileyo kwimveliso yamandla, i-metabolism, kunye nokugcina ulusu, iliso, kunye nempilo ye-nervous system. I-Deazalavin ixhaphake ngokufumaneka kukutya okunje ngobisi, amaqanda, inyama, kunye nemifuno eluhlaza, kwaye iyafumaneka nakwifomu yokongeza kwabo banokunqongophala okanye bafuna ukunyusa amanqanaba abo.
I-NMN, ngakolunye uhlangothi, i-derivative ye-niacin, eyaziwa ngokuba yi-vitamin B3, kunye ne-precursor ye-nicotinamide adenine dinucleotide (NAD +), i-coenzyme ebandakanyeka kwiinkqubo ezahlukeneyo zeselula, kubandakanywa ukuveliswa kwamandla, ukulungiswa kwe-DNA kunye ne-gene expression. I-NMN ifumene ingqwalasela ebanzi malunga neziphumo zayo zokuchasa ukuguga, njengoko ibonakaliswe ukwandisa amanqanaba e-NAD + kwii-tissue ezahlukeneyo kwaye idibaniswe nokuphuculwa komsebenzi we-metabolic kunye nokuphucula ubomi kwizifundo zezilwanyana.
Ke, yintoni umahluko phakathi kweDeazaflavin kunye ne-NMN? Omnye umahluko ophambili yindlela asebenza ngayo emzimbeni. Umsebenzi oyintloko we-Deazaflavin ufana ne-coenzyme, inceda ekuveliseni amandla kunye ne-metabolism, ngelixa i-NMN i-precursor ye-NAD +, edlala indima ebanzi ekusebenzeni kweeseli kwaye ihambelana nenkqubo yokuguga. Ngaphaya koko, ezi khompawundi zimbini zinemichiza eyahlukeneyo kwaye zicutshungulwa ngokwahlukileyo emzimbeni, kwaye i-NMN iyeyona nto iphambili ye-NAD+.
Ngokubhekiselele kwiinzuzo ezinokuthi zibekho, zombini i-Deazaflavin kunye ne-NMN ziye zadibaniswa kumanqanaba okuphucula amandla kunye nomsebenzi we-metabolic, onokuba luncedo kakhulu kubantu abajonge ukuxhasa impilo yonke kunye namandla. Nangona kunjalo, iziphumo ezinokuthi zibe kho zokuchasa ukwaluphala kwe-NMN zenze ukuba idume ngakumbi, njengoko uphando lucebisa ukuba ukonyuka kwamanqanaba e-NAD+ kunokuncedisa ukuthomalalisa ukwehla okunxulumene nobudala kunye nokwandisa ubomi.
Ukhetho phakathi kwe-Deazaflavin kunye ne-NMN lunokuxhomekeka kwiinjongo zempilo kunye neenkxalabo. Kwabo bafuna ngokuyintloko ukuxhasa ukuveliswa kwamandla kunye nempilo yonke, i-Deazaflavin inokuba yinto efanelekileyo, ngakumbi abo banolwazi olunqongopheleyo okanye izithintelo zokutya ezinokuchaphazela ukungena kwe-vitamin B2. Kwelinye icala, abantu abanomdla kwizibonelelo zokuchasa ukwaluphala kunye nokukhuthaza impilo yeselula banokufumana i-NMN ukhetho olunyanzelekileyo, ngenxa yendima yayo ekwandiseni amanqanaba e-NAD+ kunye nobudlelwane bayo nobomi obude.
Izinto ezilungileyo ze-5-deazaflavin ngaphezu kwe-NMN
I-5-Deazaflavin kunye ne-NMN powder zibalulekile zangaphambili ze-NAD + kwaye zidlala indima ebalulekileyo kwi-cell metabolism. Nangona kunjalo, xa kuthelekiswa ne-NMN,5-deazaflavin inezi zibonelelo zilandelayo:
1. Ukuzinza: i-5-deazaflavin yafunyanwa izinzile ngaphezu kwe-NMN. Oku kuthetha ukuba igcina ukusebenza kwayo ixesha elide, iyenza ibe lukhetho oluthembekileyo kwabo bafuna ukuyifaka kubomi babo bemihla ngemihla. Ukuzinza kwe-5-deazaflavin kwakhona kwenza kube lula ukugcina nokuthutha, ukunika inzuzo ngaphezu kwe-NMN ngokumalunga nokulula.
2. Ukufumaneka: Xa kuthelekiswa ne-NMN, i-5-deazaflavin ibonakaliswe ukuba ine-bioavailability ephezulu. Oku kuthetha ukuba umlinganiselo omkhulu we-5-deazaflavin ufunxwa ngumzimba, obangela umphumo ocacileyo. Ngokufumaneka kwe-bioavailability enkulu, abantu ngabanye banokufumana inzuzo ye-5-deazaflavin ngokukhawuleza kunye needosi eziphantsi kune-NMN.
3. I-Redox ikhono: i-5-deazaflavin ine-redox engathandekiyo ngakumbi kune-NMN, eyenza ukuba ithathe inxaxheba kuluhlu olubanzi lwee-biochemical reactions.
4. Ukuncedisana: I-5-deazaflavin yongezelela ezinye i-coenzymes, ezifana ne-flavin kunye ne-nicotinamide, okwenza i-cell metabolism iphelele kwaye isebenze ngakumbi.
5. Iimpawu ze-Photocatalytic: i-5-deazaflavin ibonakaliswe ukuba ineempawu ze-photocatalytic kwaye inokuba nezicelo ezinokuthi zenze kuluhlu lwamashishini.
I-6.5-i-Deazaflavin iboniswe ukuba isebenze i-sirtuins, iqela leeprotheni ezidlala indima ebalulekileyo ekulawuleni impilo yeselula kunye nobomi. Ngokusebenzisa i-sirtuins, i-5-deazaflavin inokunceda ukukhuthaza ukulungiswa kweeseli kunye nokuphucula impilo yonke kwinqanaba leselula. I-NMN, kwelinye icala, isebenza ngokuyintloko ngokunyusa amanqanaba e-NAD +, imolekyuli ebandakanyekayo kwiinkqubo ezahlukeneyo zeselula kodwa ayisebenzisi ngokuthe ngqo i-Sirtuins.
Ngokuqhelekileyo, i-5-deazaflavin powder iye ngokuthe ngcembe ibe yinto ephumayo kwi-NMN kwaye inamandla abanzi. Ngokungafani ne-NMN, isebenza ngokuthe ngqo njenge-coenzyme ngaphandle kokuguqulwa kwi-NAD + .Le propati ekhethekileyo yenza ukuba isebenze ngakumbi kune-NMN, kunye neengxelo ezichaza ukuba i-5-deazaflavin powder i-40 kumaxesha e-100 anamandla ngaphezu kwe-NMN. Ke ngoko, ithathwa njengethembisayo kwisizukulwana esilandelayo endaweni ye-NMN.
1. Ukuxhasa imveliso yamandla
Enye yeenzuzo eziphambili zezongezelelo ze-deazaflavin yindima yazo ekuxhaseni ukuveliswa kwamandla emzimbeni. I-Deazaflavin idlala indima ebalulekileyo ekuvelisweni kwe-ATP, eyona mali ingundoqo yeseli. Ngokwandisa imveliso ye-ATP, izongezelelo ze-deazaflavin zinokunceda ukunyusa amanqanaba onke amandla kunye nokulwa neemvakalelo zokudinwa kunye nokutyhafa.
2. Iimpawu ze-Antioxidant
Ii-Antioxidants ziikhompawundi ezinceda ukuthomalalisa iiradicals zasimahla eziyingozi emzimbeni ezinegalelo ekwaluphaleni nakwizifo. Ngokusebenza njenge-antioxidant, izongezo ze-deazaflavin zinokunceda ukukhusela umzimba kuxinzelelo lwe-oxidative kunye nokunciphisa umngcipheko wezifo ezingapheliyo ezifana nesifo senhliziyo kunye nesifo sikashukela.
3. Ixhasa impilo ye-nervous system.
I-Deazaflavin idlala indima ephambili ekuveliseni i-neurotransmitters, izithunywa zeekhemikhali ezivumela iiseli zemithambo-luvo ukuba zinxibelelane. Ngokuxhasa ukuveliswa kwee-neurotransmitters, izongezo ze-deazaflavin zinokunceda ukuphucula umsebenzi wokuqonda, imo, kunye nempilo yengqondo iyonke.
4. Ixhasa impilo ye-cardiovascular.
I-Deazaflavin ibonakaliswe ukuba ixhasa ukuhamba kwegazi okunempilo kwaye inokunceda ukunciphisa umngcipheko woxinzelelo lwegazi kunye nesifo senhliziyo. Ngokukhuthaza ukuhamba kwegazi okunempilo, izongezo ze-Deazaflavin zinokunceda ukuphucula ukusebenza kwezemidlalo kunye nokuxhasa ukunyamezela komzimba jikelele.
5. Ukuxhasa umsebenzi wokuzivikela omzimba
Uphando lubonisa ukuba i-deazaflavin inokunceda ukulawula amajoni omzimba kwaye inokunceda ukuxhasa impendulo enempilo yomzimba. Ngokuxhasa umsebenzi wokuzivikela omzimba, izongezo ze-deazaflavin zinokunceda ukunciphisa umngcipheko wokusuleleka kunye nokuxhasa impilo yonke.
6. Ukuchasa ukuguga
Uphononongo lufumene ukuba i-5-deazaflavin inamaxesha angama-100 asebenzayo ngaphezu kwe-NMN kwaye inokunceda ngcono ukulungiswa kwe-DNA kunye nokuchasana nokuguga.
Ukufumana isongezelelo esifanelekileyo se-deazaflavin kubalulekile ekuqinisekiseni ukuba ufumana owona mgangatho uphezulu kunye neyona mveliso isebenzayo.
Okokuqala, kubalulekile ukuqwalasela umthombo wesongezelelo sakho se-deazaflavin. Khangela inkampani ehloniphekileyo esebenzisa izithako ezikumgangatho ophezulu kwaye ekuhleni malunga nenkqubo yayo yokukhangela kunye nemveliso. Funda uphononongo lwabathengi kwaye wenze uphando kwinkampani ukuze uqiniseke ukuba banegama elihle kwishishini. Ukongeza, kuluncedo ukukhetha izongezo eziye zavavanyelwa umntu wesithathu ukucoceka kunye namandla.
Xa ukhetha isongezelelo se-deazaflavin, kubalulekile ukuqwalasela uhlobo lokuncedisa. Abanye abantu banokukhetha ii-capsules okanye iipilisi, ngelixa abanye benokukhetha ifom yomgubo. Xa uthatha isigqibo malunga nefomu yokuncedisa, qwalasela izinto ozikhethayo kunye nendlela yokuphila. Gcina ukhumbula ukuba iindlela ezahlukeneyo zezongezo zinokuba namazinga ahlukeneyo okufunxa kunye ne-bioavailability.
Enye into ephambili ekufuneka uyiqwalasele xa ukhetha isongezelelo se-deazaflavin yidosi. Idosi efanelekileyo inokwahluka ngokusekelwe kwizinto ezifana nobudala, ubunzima, kunye nempilo yonke. Kungcono ukudibana nengcali yezempilo okanye ingcali yezondlo ukuze ufumane idosi echanekileyo kwiimfuno zakho zomntu ngamnye. Kuphephe ukuthatha izongezo zedosi ephezulu kakhulu njengoko zisenokungabi yimfuneko kwaye zinokubangela iziphumo ezibi.
Ukongeza kwidosi, kukwabalulekile ukujonga isongezelelo se-deazaflavin esingenazo izongezo ezingeyomfuneko okanye izihluzi. Izongezelelo ezininzi kwiimarike ziqulethe imibala eyenziweyo, izigcina-mpahla, kunye nezinto ezinokuthi zibe yingozi kwimpilo yakho. Jonga izongezo ezicocekileyo, ezinyulu, kwaye zinezithako ezongeziweyo ezincinci.
I-Suzhou Myland Pharm & Nutrition Inc.uzibandakanye kwishishini lokongezelela isondlo ukusukela ngo-1992. Yinkampani yokuqala e-China ukuphuhlisa nokuthengisa isicatshulwa sembewu yomdiliya.
Iminyaka engama-30 yamava kwaye iqhutywa bubuchwephesha obuphezulu kunye nesicwangciso se-R&D esiphuculwe kakhulu, inkampani iphuhlise uluhlu lweemveliso ezikhuphisanayo kwaye ibe sisongezelelo sesayensi yobomi, ukuhlanganiswa kwesiko kunye nenkampani yeenkonzo zokuvelisa.
Ukongeza, inkampani ikwangumvelisi obhalisiweyo we-FDA, eqinisekisa impilo yabantu enomgangatho ozinzileyo kunye nokukhula okuzinzileyo. Izibonelelo ze-R&D zenkampani kunye nezixhobo zemveliso kunye nezixhobo zohlalutyo zezanamhlanje kwaye zinemisebenzi emininzi, kwaye ziyakwazi ukuvelisa iikhemikhali kwi-milligram ukuya kwisikali seetoni ngokuthobela imigangatho ye-ISO 9001 kunye neendlela zokuvelisa ze-GMP.
Umbuzo: Yintoni isongezelelo se-deazaflavin kwaye inokuzuza njani iinjongo zam zempilo?
A: I-Deazaflavin yikhompawundi exhasa imisebenzi eyahlukeneyo ye-metabolic emzimbeni, kubandakanya ukuveliswa kwamandla kunye nempilo yeselula. Inokuxhasa impilo yonke kunye nokunceda ngeenjongo ezithile zempilo ezifana namanqanaba okuphucula amandla kunye nenkxaso ye-antioxidant.
Umbuzo: Ndikhetha njani isongezelelo se-deazaflavin esifanelekileyo kwiimfuno zam?
A: Xa ukhetha isongezelelo se-deazaflavin, kubalulekile ukuqwalasela izinto ezinjengomgangatho, ubunyulu, kunye namandla. Khangela uphawu oluhloniphekileyo olusebenzisa izithako eziphezulu kwaye lunovavanyo lomntu wesithathu ukuqinisekisa ukuba amandla kunye nokucoceka. Ukongeza, qwalasela iinjongo zakho zempilo ezithile kwaye ujonge isongezelelo esilungiselelwe ukuxhasa ezo njongo.
Umbuzo: Kuthatha ixesha elingakanani ukubona iziphumo zokuthatha isongezelelo se-deazaflavin?
A: Ixesha elithathayo ukubona iziphumo zokuthatha isongezelelo se-deazaflavin sinokuhluka ngokuxhomekeke kwizinto ezizimeleyo ezifana nempilo yonke, ukutya kunye nendlela yokuphila. Abanye abantu banokubona ukuphucuka kumanqanaba amandla kunye nempilo jikelele ngokukhawuleza, ngelixa abanye banokuthatha ixesha elide ukufumana izibonelelo ezipheleleyo. Kubalulekile ukuhambelana nokuthatha isongezelelo njengoko kuyalelwe kwaye usinike ixesha lokusebenza.
Ukuziphendulela: Eli nqaku lelolwazi ngokubanzi kuphela kwaye akufanele lithathwe njengeliphi na icebiso lonyango. Olunye ulwazi lweposti yebhlog luvela kwi-Intanethi kwaye alunamsebenzi. Le webhusayithi inoxanduva kuphela lokuhlela, ukufomatha kunye nokuhlela amanqaku. Injongo yokudlulisa ulwazi olongezelelekileyo ayithethi ukuba uyavumelana neembono zayo okanye uqinisekise ubunyani bomxholo wayo. Soloko udibana nengcali yezempilo ngaphambi kokuba usebenzise naziphi na izongezo okanye wenze utshintsho kwirejimeni yokhathalelo lwempilo.
Ixesha lokuposa: Jan-17-2024
