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Ukubophelela amandla eBerberine: Yongeza iMpilo yakho iyonke

Indalo isinika ubuncwane obungenakubalwa xa kufikwa ekugcineni impilo, nganye ineempawu zayo ezizodwa kunye neenzuzo.Enye ilitye elifihliweyo elinjalo yiberberine, ikhompawundi efumaneka kwiintlobo ngeentlobo zezityalo ezaziwa ngeempawu zayo ezimangalisayo zokukhuthaza impilo.

Yintoni iBerberine 

 IBerberine yialkaloid etyheli eyenzeka ngokwemvelo kwiintlobo ngeentlobo zezityalo, kubandakanya iingcambu, iirhizomes, iziqu kunye namaxolo.Eminye imithombo eqhelekileyo ye-berberine ibandakanya imifuno efana ne-Oregon iidiliya, i-goldenseal, kunye ne-skullcap.Amayeza emveli aseTshayina kunye ne-Ayurvedic asebenzise amandla ezi zityalo ukunyanga izifo ezahlukeneyo kangangeenkulungwane, kwaye i-berberine ihlala ithathwa njengesithako esiphambili sokuphilisa.

Yintoni iBerberine

Ikwayeyona nto isebenzayo kwizityalo ezimbini ezidumileyo zendalo: i-coptis kunye ne-phellodendron.

IBerberine ineenzuzo ezahlukeneyo zempilo.Ukusuka ekulawuleni iswekile yegazi kunye namanqanaba e-cholesterol ukuya ekuboniseni i-antioxidant, i-antibacterial kunye ne-anti-inflammatory properties, i-berberine ngokwenene sisipho esingaqhelekanga sendalo.Nokuba isetyenziswa njengonyango oluncedisayo okanye njengendlela yokuthintela, amandla eberberine makhulu kwaye anokunceda ukudala impilo enempilo, ubomi obunamandla.

IiNzuzo zeMpilo zeBerberine

Indima yeBerberine ekulawuleni isifo seswekile

Isifo seswekile sisifo esinganyangekiyo esichaphazela izigidi zabantu kwihlabathi liphela.Ibonakala ngeswekile ephezulu yegazi ngenxa yokunqongophala komzimba kwimveliso ye-insulin okanye ukungakwazi kwayo ukusebenzisa i-insulin ngokufanelekileyo.

Ukuxhathisa i-insulin luphawu lohlobo lwe-2 yeswekile, apho impendulo yomzimba kwimiphumo ye-insulin iyancipha.Uphando luye lwafumanisa ukuba i-berberine inokuphucula ukufunyanwa kwe-glucose kwiselula, ngaloo ndlela inceda ukulawula amanqanaba eswekile yegazi.Kwakhona kunciphisa imveliso ye-glucose esibindini, inceda ngakumbi ekuphuculeni ulawulo lweswekile yegazi.

Ukongezelela, i-berberine ibonakaliswe ukuba inqanda ukuveliswa kwamanqaku okuvuvukala, ukunciphisa ukuvuvukala, kunye nokuthintela iingxaki zesifo sikashukela ezifana nesifo senhliziyo kunye nomonakalo wezintso.

Ukongeza kwimiphumo yayo kwi-insulin sensitivity kunye nokuvuvukala, i-berberine ibonise amandla okuphucula iphrofayili ye-lipid.Isifo seswekile sonyusa umngcipheko we-dyslipidemia, ebonakaliswa ngamanqanaba aphezulu e-cholesterol kunye ne-triglyceride.Uphando lufumene ukuba i-berberine inokunciphisa i-cholesterol epheleleyo, i-cholesterol ye-LDL, kunye namanqanaba e-triglyceride ngelixa inyusa i-cholesterol ye-HDL, ngaloo ndlela inika iphrofayili ye-lipid ethandekayo.

Indima yeBerberine ekulawuleni isifo seswekile

Inganceda iNkxaso yeMpilo yeNtliziyo

Uphando lufumene ukuba i-berberine ineempawu ezahlukeneyo ezinokuxhasa impilo yentliziyo.Inokulawula iswekile yegazi kunye nemiphumo yokunciphisa i-lipid, ebaluleke kakhulu ekugcineni impilo ye-cardiovascular.

Uphando lufumene ukuba i-berberine yenza i-enzyme ebizwa ngokuba yi-adenosine monophosphate-activated protein kinase (AMPK), edlala indima ebalulekileyo ekubonakalisweni kwe-insulin kunye ne-glucose metabolism.Ngokwandisa uvakalelo lwe-insulin, i-berberine inokunceda ukulawula amanqanaba eswekile yegazi kunye nokunciphisa umngcipheko wokuphazamiseka kwe-metabolic, okunokuthi kube nefuthe elibi kwimpilo yentliziyo.

Uphando lubonisa ukuba i-berberine inokuphucula ukusebenza kwentliziyo ngokunyusa ukunyanzeliswa kwemisipha yenhliziyo kunye nokunciphisa uxinzelelo lwe-oxidative.Ngokwandisa amandla kunye nokusebenza kakuhle kwemisipha yenhliziyo, i-berberine inokufaka isandla kwimpilo ye-cardiovascular system.

Okwangoku, ukwamkela indlela yokuphila esempilweni, kubandakanywa ukutya okunesondlo, umthambo rhoqo kunye nokuhlolwa kwempilo rhoqo, kuhlala kubalulekile ekugcineni intliziyo esempilweni.

Inganceda iNkxaso yeMpilo yeNtliziyo

Berberine ekuxhaseni ukuthoba iCholesterol

Uphando lubonisa ukuba i-berberine inokunciphisa ngokufanelekileyo i-cholesterol epheleleyo, i-cholesterol ye-LDL, kunye namanqanaba e-triglyceride, ngelixa inyusa i-cholesterol ye-HDL.Ezi ziphumo ze-lipid-ukunciphisa i-berberine zinokunceda kakhulu ukugcina iphrofayili ye-lipid enempilo kunye nokunciphisa umngcipheko wesifo senhliziyo.

I-Berberine yenza iziphumo zayo zokunciphisa i-cholesterol ngokuthintela i-enzyme ebizwa ngokuba yi-PCSK9.I-PCSK9 idlala indima ebalulekileyo ekulawuleni amanqanaba e-cholesterol ye-LDL egazini.Xa i-PCSK9 isebenza ngokugqithiseleyo, ikhokelela kumanqanaba aphezulu e-cholesterol ye-LDL, ekhokelela ekubunjweni kwe-plaque kwi-artery kwaye ekugqibeleni isifo senhliziyo.I-Berberine iboniswe ukuba inqanda imveliso ye-PCSK9, ngaloo ndlela inciphisa amanqanaba e-cholesterol ye-LDL kunye nokuphucula impilo ye-cardiovascular. 

Ukongezelela, i-berberine ifunyenwe ichaphazela i-cholesterol synthesis kwisibindi.Ithintela i-enzyme ebizwa ngokuba yi-HMG-CoA reductase, ejongene nokuveliswa kwe-cholesterol emzimbeni.Ngokuthintela le enzyme, i-berberine inciphisa i-cholesterol synthesis kwaye ikhokelela ekunciphiseni amanqanaba e-cholesterol ye-LDL.

Ukongeza kwiziphumo zayo kwi-cholesterol, i-berberine nayo inezixhobo ezichasayo kunye ne-antioxidant, ezinegalelo ngakumbi kwiinzuzo zayo zentliziyo.Ukuvuvukala okungapheliyo kunye noxinzelelo lwe-oxidative zizinto ezaziwa njengengozi yesifo senhliziyo.Uphando lufumene ukuba i-berberine inokuthintela ukuveliswa kwee-molecule ezivuthayo kunye nokukhuthaza umsebenzi we-antioxidant enzymes, ekugqibeleni ukunciphisa umngcipheko weengxaki ze-cardiovascular.

Ithuba leBerberine lokuLahla kobunzima

I-Berberine ibonakaliswe ukwandisa i-glucose metabolism, ngaloo ndlela inceda ukulawula amanqanaba eswekile yegazi.Ngokuphucula uvakalelo lwe-insulin, i-berberine inceda umzimba ukuba usebenzise i-glucose ngokufanelekileyo kwaye ikhusela i-glucose engaphezulu ukuba iguqulwe ibe yindawo yokugcina amafutha. 

Ukongezelela, i-berberine inamandla okukhuthaza i-lipolysis ngokuvula i-enzyme ebizwa ngokuba yi-adenosine monophosphate-activated protein kinase (AMPK).Le enzyme yaziwa ngokuba yi "metabolic master switch" kuba idlala indima ebalulekileyo ekulawuleni umetabolism wamandla kunye nokunceda ukunciphisa umzimba.Ngokusebenzisa i-AMPK, i-berberine inokunceda ukukhuthaza i-oxidation ye-fat and inhibit fat synthesis, ekhokelela ekulahlekeni kwesisindo.

I-Berberine ifunyenwe ichaphazela i-gut microbiome, edlala indima ebalulekileyo ekulawuleni ubunzima.Uphando lubonisa ukuba i-berberine inokutshintsha ukubunjwa kwe-intestinal microbiota, ukukhuthaza ukukhula kweebhaktheriya ezincedo kunye nokuvimbela ukukhula kweebhaktheriya eziyingozi.I-balanced gut microbiome ibalulekile ekugcineni ubunzima obunempilo kuba ichaphazela ukutsalwa kwamandla ekutyeni kwaye ilawula imetabolism.

Nangona kunjalo, kubalulekile ukukhumbula ukuba ukwehla kobunzima yinkqubo entsonkothileyo ephenjelelwa zizinto ezininzi, kubandakanya ukutya, umthambo, kunye nokukhetha indlela yokuphila.Ukuthatha i-berberine njengenxalenye yendlela yokulawula ubunzima ngokubanzi kunokubonelela ngenkxaso eyongezelelweyo ekufezekiseni nasekugcineni ubunzima obunempilo.

Ithuba leBerberine lokuLahla kobunzima

Ikhonkco phakathi kweBerberine kunye neGut Health

Uphando lubonisa ukuba i-berberine inokunceda ukubuyisela kunye nokugcina i-microbiome enempilo yamathumbu.Uphando olupapashwe kwijenali yezoNxibelelwano lweNdalo lufumanise ukuba iberberine yonyusa iyantlukwano yeebhaktheriya zamathumbu, ikhuthaza ukukhula kohlobo oluluncedo olunje ngeBifidobacterium kunye neLactobacillus.Ezi bhaktheriya ziyaziwa ngemiphumo yazo yokukhusela ekuvukeleni kunye nokuphucula umsebenzi wokuthintela amathumbu.

Olunye uphononongo olupapashwe kwijenali yeFrontiers kwiMicrobiology yaqaqambisa iipropathi zokulwa neentsholongwane zeberberine.Kufunyenwe ukuthintela ukukhula kweebhaktheriya ezinobungozi ezahlukeneyo, kuquka i-E. coli kunye ne-salmonella.Ngokunciphisa inani le-pathogenic microorganisms, i-berberine inokunceda ukubuyisela i-microbiome yamathumbu kunye nokukhuthaza inkqubo yokugaya ephilileyo.

Ukongeza kwiziphumo zayo ezithe ngqo kwiibhaktheriya zamathumbu, i-berberine ifunyenwe ukulawula ukuveliswa kwee-enzymes ezahlukeneyo zokugaya.Ezi enzymes zinoxanduva lokuqhekeza ukutya kunye nokuqinisekisa ukufunxa ngokufanelekileyo izondlo.Uphando lubonisa ukuba i-berberine inokuphucula umsebenzi wee-enzymes ezithile, ezifana ne-amylase kunye ne-lipase, ngaloo ndlela iphucula ukugaya kunye nokusetyenziswa kwezondlo.

Izongezelelo kunye neThamo, iziphumo ezisecaleni 

I-Berberine inokongezwa kubomi bomntu ngendlela yezongezo zokutya, eyona nto ixhaphakileyo yi-berberine hydrochloride.

Umthamo wedosi epapashiweyo:

Ukumisela idosi efanelekileyo yezongezelelo zeberberine kunokuba ngumsebenzi onzima.Ziliqela izinto ezidlala indima ebalulekileyo, kuquka impilo yakho kunye neziphumo ezinqwenelekayo.Ngokuqhelekileyo, kucetyiswa ukuba uqale ngedosi ephantsi kwaye ngokuthe ngcembe wandise umthamo ngokuhamba kwexesha.Ukufumana inkxaso yezempilo jikelele, imilinganiselo yedosi esemgangathweni yi-500 mg ukuya kwi-1500 mg ngosuku, yahlulahlulwe kwiidosi ezininzi.Nangona kunjalo, kubalulekile ukubonisana nochwepheshe bezempilo okanye ulandele izikhokelo ezingqalileyo zemveliso kwiingcebiso zedosi yomntu ngamnye. 

 Lumkela iziphumo ebezingalindelekanga:

Ngelixa i-berberine ineenzuzo ezilungileyo zempilo, kubalulekile ukuqwalasela iziphumo ebezingalindelekanga ezinokubakho.Njengaso nasiphi na isongezelelo, isenokungafanelanga wonke umntu.Abanye abantu banokufumana ukungonwabi kwesisu njengorhudo, ukuqunjelwa, okanye iintlungu zesisu.Ukongezelela, i-berberine inokunxibelelana namayeza athile, kubandakanywa nalawo axutywe sisibindi.Ke ngoko, kubalulekile ukudibana nengcali yezempilo ngaphambi kokufaka izongezo zeberberine kubomi bakho bemihla ngemihla.

Ngelixa izongezo ze-berberine zibonwa ngenxa yeenzuzo zazo zempilo ezinokubakho, kubalulekile ukukhumbula ukuba impilo entle ixhomekeke ngaphezulu kunezongezo nje.Ukutya okunokulinganisela, umsebenzi oqhelekileyo womzimba kunye nokulala ngokwaneleyo zizinto eziphambili kwimpilo yonke.I-Berberine kufuneka ithathwe njengesongezelelo kwindlela yokuphila enempilo kunesisombululo esizimeleyo.

Umbuzo: Ngaba i-berberine inokunceda ukunciphisa umzimba?
A: Ewe, uphando lubonise ukuba i-berberine inokunceda ekulahlekeni kwesisindo ngokunyusa i-metabolism, ukunciphisa i-fat synthesis, kunye nokukhuthaza ukuchithwa kwamafutha.
Umbuzo: Ndingazifumana phi izongezo zeberberine?
A: Izongezelelo zeBerberine zinokufumaneka kwiivenkile ezahlukeneyo zokutya, iikhemesti, kunye nabathengisi be-intanethi.Jonga iibrendi ezithembekileyo ezibonelela ngolwazi olungafihliyo malunga nokufunyanwa kwemveliso, ukucoceka, kunye nomgangatho.

Ukuziphendulela: Esi sithuba seblogi sisebenza njengolwazi oluqhelekileyo kwaye akufanele luthathwe njengengcebiso yezonyango.Soloko udibana nengcali yezempilo ngaphambi kokuba usebenzise naziphi na izongezo okanye wenze utshintsho kwirejimeni yokhathalelo lwempilo.

Ixesha lokuposa: Sep-21-2023