Yintoni i-Trigonelline HCl kwaye kutheni kufuneka ukhathalele?

Kwihlabathi lezempilo kunye nokuphila kakuhle, kuhlala kugxilwa kwiikhompawundi ezahlukeneyo ezineenzuzo ezahlukeneyo. Enye ikhompawundi ethe yatsala umdla kwiminyaka yakutshanje yi-Trigonelline HCl. I-Trigonelline hydrochloride yialkaloid eyenzeka ngokwemvelo efumaneka kwiintlobo ngeentlobo zezityalo, ngakumbi imbewu yefenugreek kunye neembotyi zekofu. Iphuma kwi-amino acid niacin kwaye iyaziwa ngesakhiwo sayo esisodwa sekhemikhali esivumela ukuba idibane neenkqubo ezahlukeneyo zebhayoloji emzimbeni. I-"HCl" egameni layo ibhekisa kwifom yayo ye-hydrochloride, eyandisa ukunyibilika kwayo kunye ne-bioavailability, okwenza kube lula ukuba umzimba ufunxe.

Intshayelelo yemveliso

I-Trigonelline HCl(CAS: 6138-41-6) ngumgubo omhlophe omhlophe. I-Trigonelline HCl yityuwa eyenziwe emva kokusabela kwe-trigonelline kunye ne-hydrochloric acid. Iikhompawundi, ifom yetyuwa idla ngokuba ne-solubility engcono kunye nokuzinza. I-Trigonelline, ekwabizwa ngokuba yi-niacin betaine, kwaye igama layo lezenzululwazi yi-trimethylxanthine, yikhompawundi ene-nitrogen ene-alkaline ebonakala njengomgubo omhlophe wekristale kwaye iyanyibilika kwi-methanol nasemanzini. I-Trigonelline yeyona nto iphambili ye-alkaloid ye-fenugreek kwaye inemisebenzi eyahlukeneyo yebhayoloji, kubandakanya i-antioxidant, i-anti-inflammatory, kunye nolawulo lweswekile yegazi. I-Trigonelline hydrochloride ikwabonisa iziphumo ezifanayo ngokwemigaqo ye-bioactivity, kodwa inokuba nenzuzo kwi-bioavailability ngenxa yokunyibilika kwayo okungcono.

Umsebenzi wosetyenziso

Iswekile yegazi ephantsi

Uphononongo lubonise ukuba kwiigundane zesifo sikashukela sohlobo lwe-2, i-trigonelline inokunciphisa iswekile yegazi kunye namanqanaba e-insulin, yandise i-insulin sensitivity index, kwaye yandise ubunzima be-pancreatic, i-pancreas-to-body weight ratio, kunye nobunzima be-pancreas ngokukhuthaza ukuvuselelwa kweseli ye-beta kunye nokunciphisa ukumelana ne-insulin. . Umxholo we-insulin, ngaloo ndlela unciphisa amanqanaba eswekile yegazi.

Ukuchasa ukuguga

Uphando lubonisa ukuba ukuxhaswa kwe-trigonelline kunokunyusa amanqanaba e-NAD + kunye nokwandisa umsebenzi we-mitochondrial, ngaloo ndlela kunceda ukuphucula inkqubo yokuguga. Ngokomzekelo, kwi-nematodes, i-trigonelline inokunciphisa i-atrophy ye-muscle ngenxa yobudala kunye nokwandisa ubomi; kwiimpuku, i-trigonelline inokomeleza ngokufanelekileyo amandla emisipha kunye nokunciphisa ukudinwa ngexesha lokuguga.

Ukuphucula ukusebenza kwengqondo

Uphononongo lubonise ukuba i-trigonelline inokuphucula ukuhla kwememori kwiimpuku eziguga ngokuthintela ukuveliswa kwezinto ezibangela ukudumba kunye nokukhuthaza ukukhululwa kwee-neurotransmitters. Ukongeza, i-trigonelline inokuphinda ikhuthaze ukukhula okusebenzayo kwe-synapse kwiiseli zabantu ze-SK-N-SH, ezinokunxulumana nendlela yokuphucula inkumbulo.

Iilipids ezisezantsi zegazi

Kwi-GK uhlobo lwe-2 yesifo sikashukela, i-trigonelline yanciphisa i-serum kunye ne-hepatic triglyceride amanqanaba, ukunciphisa umsebenzi we-hepatic fatty acid synthase, kunye nokwandisa i-hepatic carnitine palmitoyltransferase kunye nemisebenzi ye-glucokinase.

Ukusetyenziswa kwemizi-mveliso ye-Trigonelline HCl

I-Trigonelline inemisebenzi eyahlukeneyo ye-physiological, kuquka i-antioxidant, ukunciphisa iswekile yegazi, ukutshabalalisa i-radicals yamahhala, ukuphucula umsebenzi we-mitochondrial, ukwandisa amandla emisipha, ukunciphisa umonakalo weseli, ukuphucula umsebenzi wokuqonda, njl. Ngokusekelwe kule nto, i-Trigonelline HCl isetyenziswa ngokuqhelekileyo kwi-pharmaceuticals. kushishino, isetyenziswa njengesithako esisebenzayo kumachiza.

Ungayithenga phi i-Trigonelline HCl?

Kwihlabathi lezondlo zanamhlanje kunye nempilo, i-Trigonelline HCl ifumana ingqwalasela eyongeziweyo kwiinzuzo zayo ezininzi zempilo ezinokubakho. Njenge-alkaloid eyenzeka ngokwemvelo, i-Trigonelline HCl ikhutshwa ikakhulu kwiimbotyi kunye nezityalo ezithile kwaye isetyenziswa ngokubanzi kwiimveliso zempilo kunye nokutya okusebenzayo. Ngokunyuka kwemfuno yabathengi yezithako zendalo, imfuno yomgangatho ophezulu we-Trigonelline HCl powder nayo iyanda kwimarike,

Xa uthenga i-Trigonelline HCl, umgangatho ubaluleke kakhulu. Kufuneka uqinisekise ukuba uthenga kumthengisi othembekileyo onika iimveliso ezisemgangathweni.Xa ukhangela "i-trigonelline hydrochloride," qiniseka ukuba ujonge uvavanyo lomntu wesithathu kunye nesiqinisekiso sokuqinisekisa ukucoceka kwemveliso kunye namandla. Ukufunda ukuphononongwa kwabathengi kunokubonelela ngengqiqo ekusebenzeni kwemveliso kunye nokuthembeka komthengisi.

1. Umgangatho wemveliso

Xa ukhetha umthengisi, into yokuqala ekufuneka uyiqwalasele ngumgangatho wemveliso. Ukucoceka okuphezulu kwe-Trigonelline HCl powder iqinisekisa umsebenzi wayo webhayoloji kunye nokusebenza kakuhle. I-Trigonelline HCl powder enikezwe nguSuzhou Myland iye yavavanywa ngokungqongqo umgangatho wokuqinisekisa ukuba ibhetshi nganye yeemveliso ihlangabezana nemigangatho yamazwe ngamazwe kwaye inomgangatho oqinisekisiweyo.

2. Umthamo wemveliso

Umthamo wemveliso yomenzi uchaphazela ngokuthe ngqo ixesha kunye nokuzinza kokubonelela. I-Suzhou Myland inezixhobo eziphambili zemveliso kunye nobuchwepheshe obunokuhlangabezana neemfuno zemveliso yobuninzi, iqinisekisa ukuba abathengi banokufumana iimveliso abazifunayo ngexesha xa bezifuna.

3. Izakhono zeR&D

Umthengisi ogqwesileyo uhlala eneqela eliqinileyo le-R&D elinokuthi ngokuqhubekayo liphucule iimveliso kunye nokuphuhlisa iimveliso ezintsha. I-Suzhou Myland iqokelele amava atyebileyo kuphando kunye nokusetyenziswa kwe-Trigonelline HCl kwaye iyakwazi ukubonelela abathengi ngenkxaso yobuchwephesha kunye nezisombululo.

4. Inkonzo yabaThengi

Inkonzo elungileyo yabathengi yinto engenakuhoywa xa ukhetha umthengisi. I-Suzhou Myland igxile kunxibelelwano kunye nabathengi kwaye iyakwazi ukubonelela ngeenkonzo zomntu ngokweemfuno zabathengi ukuqinisekisa ukuba abathengi bafumana amava angcono ngexesha lokuthenga.

5. Isiqinisekiso kunye nokuThobela

Ukuqinisekisa ukuba ababoneleli banezatifikethi ezifanelekileyo kunye nokuthotyelwa ziikhrayitheriya ezibalulekileyo zokukhethwa. I-Suzhou Myland yi-ISO eqinisekisiweyo kwaye ihambelana nemigangatho ye-GMP (i-Good Manufacturing Practice), iqinisekisa ukuba iimveliso zayo zilandela inkqubo yokulawula umgangatho ongqongqo ngexesha lenkqubo yokuvelisa.

Njengomvelisi we-Trigonelline HCl powder, i-Suzhou Myland iphumelele ukuthembela kwabathengi abaninzi kunye neemveliso zayo ezicocekileyo kunye nokulawula umgangatho ongqongqo. Inkampani izibophelele ekuboneleleni abathengi ngemathiriyeli ekrwada ekumgangatho ophezulu kwaye ibancede baphumelele kumashishini abo.

Ukukhetha umboneleli ofanelekileyo we-Trigonelline HCl ngundoqo ekuqinisekiseni umgangatho wemveliso kunye nokhuseleko. I-Suzhou Myland iye yaba lukhetho oluthembekileyo kwishishini kunye neemveliso zayo ezicocekileyo, ulawulo olungqongqo lwekhwalithi kunye neenkonzo zobungcali. Ingaba ungumenzi wemveliso yokhathalelo lwempilo okanye inkampani yokutya, iSuzhou Myland inokukunika umgangatho ophezulu weTrigonelline HCl powder ukunceda impilo yakho kunye nophuhliso lomsebenzi. Ukufumana iinkcukacha ezithe vetshe, nceda undwendwele iwebhusayithi ye-Suzhou Myland esemthethweni.