Yintoni umahluko phakathi kwe-spermidine trihydrochloride kunye ne-spermidine? Zitsalwa phi?

I-Spermidine trihydrochloridekunye ne-spermidine zikhompawundi ezimbini ezinxulumeneyo ezithi, nangona zifana kwisakhiwo, zineeyantlukwano ezithile kwiipropati zazo, ukusetyenziswa, kunye nemithombo yokukhutshwa.

I-Spermidine yi-polyamine eyenzeka ngokwemvelo ekhoyo ngokubanzi kwizinto eziphilayo, ngokukodwa idlala indima ebalulekileyo ekukhuleni kweeseli kunye nokukhula. Ubume bayo bemolekyuli buqulethe amaqela amaninzi e-amino kunye nee-imino kwaye inomsebenzi onamandla we-biological. Utshintsho loxinzelelo lwe-spermidine kwiiseli luhambelana ngokusondeleyo kwiinkqubo ezahlukeneyo ze-physiological, kubandakanywa ukwanda kweeseli, ukuhlukana, i-apoptosis kunye ne-anti-oxidation. Imithombo ephambili ye-spermidine ibandakanya izityalo, izilwanyana kunye ne-microorganisms, ngokukodwa kwi-fermented foods, iimbotyi, amantongomane kunye nemifuno ethile.

I-Spermidine trihydrochloride yindlela yetyuwa ye-spermidine, ngokuqhelekileyo ifunyenwe ngokuphendula i-spermidine nge-hydrochloric acid. Xa kuthelekiswa ne-spermidine, i-spermidine trihydrochloride ine-solubility ephezulu emanzini, eyenza ibe luncedo ngakumbi kwizicelo ezithile. I-Spermidine trihydrochloride iqhele ukusetyenziswa kuphando lwebhayoloji kunye neshishini loxubo mayeza njengesongezo kwinkcubeko yeeseli kunye novavanyo lwebhayoloji. Ngenxa yokunyibilika kwayo okulungileyo, i-spermidine trihydrochloride isetyenziswa kakhulu kwimidiya yenkcubeko yeeseli ukukhuthaza ukukhula kweeseli kunye nokwanda.

Ngokumalunga nokutsalwa, i-spermidine idla ngokufunyanwa ngokutsalwa kwemithombo yendalo, njengokukhupha amacandelo e-polyamine kwizityalo. Iindlela eziqhelekileyo zokukhutshwa zibandakanya ukutsalwa kwamanzi, ukukhutshwa kotywala kunye ne-ultrasonic extraction. Ezi ndlela zinokuhlula ngokufanelekileyo i-spermidine kwizinto eziluhlaza kwaye zihlambulule.

Ukukhutshwa kwe-spermidine trihydrochloride kulula kwaye ngokuqhelekileyo kufunyanwa ngokuhlanganiswa kweekhemikhali phantsi kweemeko zebhubhoratri. I-Spermidine trihydrochloride inokufumaneka ngokuphendula i-spermidine nge-hydrochloric acid. Le ndlela yokudibanisa ayiqinisekisi kuphela ukucoceka kwemveliso, kodwa ivumela ukugxilwa kwayo kunye nefomula ukuba ilungiswe njengoko kufuneka.

Ngokwesicelo, zombini i-spermidine kunye ne-spermidine trihydrochloride zisetyenziswa ngokubanzi kuphando lwe-biomedical. I-Spermidine isoloko yongezwa kwiimveliso zezempilo kunye nezongezelelo zondlo zokunceda ukuphucula ukusebenza kweeseli kunye nokunciphisa inkqubo yokuguga ngenxa yendima yayo ekwandeni kweeseli kunye nokuchasana nokuguga. I-Spermidine trihydrochloride isoloko isetyenziswa kwinkcubeko yeeseli kunye novavanyo lwebhayoloji njengokukhuthaza ukukhula kweeseli ngenxa yokunyibilika kwayo okugqwesileyo.

Ngokuqhelekileyo, kukho ukungafani phakathi kwe-spermidine kunye ne-spermidine trihydrochloride kwisakhiwo kunye neepropati. I-Spermidine yi-polyamine eyenzeka ngokwemvelo, ngokukodwa ekhutshwe kwizityalo kunye nezicubu zezilwanyana, ngelixa i-spermidine trihydrochloride ifom yetyuwa, ngokuqhelekileyo ifunyenwe ngokusebenzisa i-chemical synthesis. Zombini zinexabiso elibalulekileyo kuphando lwe-biomedical kunye nezicelo. Ngokunzulu kophando lwezenzululwazi, iindawo zabo zesicelo ziya kuqhubeka zisanda, zibonelela ngamathuba amaninzi ophando lwezempilo kunye nonyango.