Ekufuneni impilo epheleleyo kunye nokuphila kakuhle, indalo isoloko isinika i-treasure trove yeekhompawundi ezinamandla kunye neenzuzo ezahlukeneyo. Enye ikhompawundi efumene ingqalelo kwiminyaka yakutshanje yi-dehydrozingerone. Ethathwe kwijinja, i-dehydrozingerone yikhompawundi ye-bioactive enamandla amakhulu okukhuthaza impilo yonke kunye nokuphila kakuhle. Ineenzuzo ezahlukeneyo, kubandakanywa ne-anti-inflammatory, i-antioxidant properties, eyenza ukuba ibe yinto exabisekileyo kwi-arsenal yethu yendalo yokukhuthaza impilo. Ngokuvula amandla e-dehydrozingerone, sinokuthatha inyathelo ekufezekiseni eyona mpilo iphezulu kunye namandla.
Dehydrozingeroneyinto eyenzeka ngokwemvelo kwijinja, isiqholo esithandwayo kunye nemifuno ebisetyenziswa kwiinkqubo zamayeza esintu kangangeenkulungwane. Yeyodidi lweekhompawundi ezibizwa ngokuba yi-gingerols, ezinoxanduva lweenzuzo ezininzi zempilo ezinxulumene nejinja. I-Dehydrozingerone i-structural efana ne-curcumin, kodwa i-bioavailability yayo iphezulu kakhulu ngenxa yokukwazi ukuxubana namanzi. I-Dehydrozingerone yenziwa ngokuphelelwa ngamanzi emzimbeni yenye i-gingerol compound (i-6-gingerol) kwaye inokwakheka kweekhemikhali ezizodwa kunye nomsebenzi webhayoloji.
I-Dehydrozingerone inezi zakhono zilandelayo:
●Ukuphucula ukulawulwa kweswekile yegazi
●Umsebenzi onamandla we-antioxidant, ngakumbi ngokuchasene nokutya okucutshungulweyo / ioyile
●Iimpawu ezichasayo
●Impembelelo yokuchasana nokukhula kweseli engafanelekanga
●Umoya uphucukile
I-Dehydrocyanin ivuselela i-AMP-activated protein kinase (AMPK), enceda ukuphucula umsebenzi we-metabolic kunye nokunyuka kwe-glucose engcono. Kuthatyathwe kunye, oku kubangela ukuguga okunamandla kunye nemiphumo yokulahlekelwa kwesisindo kwaye kunokuba nethemba ngakumbi kune-curcumin ngokwayo.
DehydrozingeroneYikhompawundi yodidi lwephenolic organic compound. Iphuma kwi-zingerone, ikhompawundi yendalo efumaneka kwijinja.
Isakhiwo se-dehydrozingerone siqukethe i-phenolic ring kunye neqela le-ketone kunye ne-double bond. I-formula yekhemikhali ye-dehydrozingerone yi-C11H12O3, kwaye ubunzima bayo be-molecular yi-192.21 g / mol. Isakhiwo semolekyuli ye-dehydrozingerone ibonakaliswe kubukho bentsimbi emnandi enamalungu amathandathu kunye neqela le-hydroxyl (OH) eqhotyoshelweyo. Ukongezelela, kukho iqela le-ketone (C = O) kunye ne-double bond (C = C) kwisakhiwo.
Ubukho beringi ye-phenolic kwi-dehydrozingerone inquma iimpawu zayo ze-antioxidant. Iikhompawundi ze-Phenolic ziyaziwa ngokukwazi ukukhupha ii-radicals zasimahla kunye nokukhusela iiseli kumonakalo owenziwe yi-oxidative. Oku kwenza i-dehydrozingerone ibe luncedo ekulweni noxinzelelo lwe-oxidative kunye nokunciphisa umngcipheko wezifo ezingapheliyo ezinxulumene nomonakalo omkhulu wamahhala.
Ngaphezu koko, iqela le-ketone kwisakhiwo se-dehydrozingerone linegalelo ekusebenzeni kwakhona kunye nokusebenza kwezinto eziphilayo. I-Ketones ngamaqela asebenzayo asebenzayo anokuthi athathe inxaxheba kwiintlobo ezahlukeneyo zeekhemikhali, okwenza i-dehydrozingerone i-molecule enomdla kwi-chemistry yamayeza kunye nokufumanisa iziyobisi.
Iibhondi eziphindwe kabini kwisakhiwo se-dehydrozingerone nazo zandisa ukusetyenziswa kweekhemikhali kwaye zinokudlala indima kwimisebenzi yayo yezinto eziphilayo. Iibhondi eziphindwe kabini zinokungena kwiimpendulo zokongezwa, kwaye ubukho bazo kwiikhompawundi zezinto eziphilayo buhlala buchaphazela iipropati zabo zomzimba kunye neekhemikhali.
Ngokubhekiselele kwimiphumo ye-biological, i-dehydrozingerone ifundwe kwiimpawu zayo ezichasayo. Ukuvuvukala kukusabela kwemvelo kwe-immune kukwenzakala okanye usulelo, kodwa ukuvuvukala okungapheliyo kunokukhokelela ekuphuhliseni izifo ezahlukeneyo. I-Dehydrozingerone ibonise amandla okulungelelanisa iindlela ezivuthayo kunye nokunciphisa ukuveliswa kwee-molecule ze-pro-inflammatory kwiiseli.
Ubume be-dehydrozingerone buphinda bube ngumgqatswa wophando olongezelelweyo kwiinkalo zekhemistri yemveliso yendalo kunye nophuhliso lwamachiza. Ukuqonda iimpawu zabo zeekhemikhali kunye nokusebenza kwakhona kunokunceda ekuyilweni kwezinto eziphuma kuyo kunye nomsebenzi ophuculweyo webhayoloji okanye iimpawu eziphuculweyo ze-pharmacokinetic.
1. Iimpawu zayo ezichasayo
Ukudumba yindlela yendalo eyenziwa ngumzimba kukwenzakala okanye usulelo, kodwa xa sele igugile, inokuba negalelo ekukhuleni kwezifo ezahlukahlukeneyo, kuquka isifo samathambo, isifo sentliziyo kunye nomhlaza. I-Dehydrozingerone ibonakaliswe ukuthintela ukuveliswa kwabalamli abavuthayo kunye nokunciphisa ukubonakaliswa kwezakhi zofuzo ezivuthayo, okwenza kube ngumviwa onokuthi uphuhlise iziyobisi ezichasayo.
Iimpawu ze-2.Antioxidant
Uxinzelelo lwe-oxidative lwenzeka xa kukho ukungalingani phakathi kokuveliswa kweeradicals zamahhala kunye nokukwazi komzimba ukuzinciphisa, kwaye kudibaniswa nokuphuhliswa kwezifo ezahlukeneyo, kuquka izifo ze-neurodeergenerative, isifo senhliziyo kunye nomhlaza. I-Dehydrozingerone ibonakaliswe ukuba ikhuphe i-radicals yamahhala kwaye ikhusele iiseli emonakalweni we-oxidative, iphakamisa ukuba inokuba namandla njenge-antioxidant yendalo.
3. Iipropati ezinokuthi zichase umhlaza
Umhlaza sisifo esintsonkothileyo nesinamacala amaninzi, kwaye ukufumana unyango olusebenzayo kuhlala kungumngeni omkhulu. Uphando lubonisa ukuba i-dehydrozingerone inokuthintela ukukhula kunye nokwanda kweeseli zomhlaza, ibangele i-apoptosis (ukufa kweseli ecwangcisiweyo) kwiiseli zomhlaza, kwaye inqanda ukwakheka kwemithambo yegazi emitsha eyimfuneko ekukhuleni kwethumba. Ezi ziphumo zibonisa ukuba i-dehydrozingerone inokuba namandla njenge-arhente ye-anticancer, nokuba yodwa okanye idibene namanye amachiza omhlaza.
4. Iimpembelelo kwi-cardiovascular system
Isifo senhliziyo, esibandakanya isifo senhliziyo kunye nesifo sohlangothi, sesona sizathu siphambili sokufa kwihlabathi liphela. I-Dehydrozingerone ibonakaliswe ukuba ineempembelelo ze-vasodilatory, oku kuthetha ukuba ikhulula kwaye yandise imithwalo yegazi, enokunceda ukunciphisa uxinzelelo lwegazi kunye nokuphucula ukuhamba kwegazi. Ukongezelela, kufunyenwe ukuthintela ukubunjwa kwegazi, eyona nto ibangela ukuhlaselwa yintliziyo kunye nokubetha. Ezi ziphumo zibonisa ukuba i-dehydrozingerone inokuba namandla okukhusela kunye nokunyanga isifo senhliziyo.
Ukongeza kwiipropathi zayo ze-pharmacological, i-dehydrozingerone nayo ifundelwe ukusetyenziswa kwayo kumashishini okutya kunye ne-cosmetic. Njengomxube wendalo kunye ne-antioxidant kunye ne-anti-inflammatory properties, isetyenziswa njengento yokugcina ukutya okanye i-additive kunye nemveliso yokunakekelwa kwesikhumba. Ukukwazi ukukhupha ii-radicals zamahhala kunye nokunciphisa ukuvuvukala kunokwenza ukuba ibe yinto ebalulekileyo ekuphuhliseni ukutya okusebenzayo kunye neemveliso zokunakekelwa kwesikhumba.
1. Umgangatho kunye nobunyulu
Xa ukhetha isongezelelo se-dehydrozingerone, kubalulekile ukubeka phambili umgangatho kunye nokucoceka. Khangela iimveliso ezenziwe ziinkampani ezithembekileyo kwaye zivavanywe ngokungqongqo ubunyulu kunye namandla. Khetha izongezo ezingenazo izongezo, izihluzi, kunye nezithako ezenziweyo. Ukongeza, qwalasela ukukhetha iimveliso eziqinisekisiweyo ze-organic ukuqinisekisa ukuba ufumana isongezelelo sendalo esikumgangatho ophezulu.
2. Ukufumaneka kwezinto eziphilayo
I-Bioavailability ibhekiselele kubuchule bomzimba bokufunxa kunye nokusetyenziswa kwento ethile. Xa ukhetha isongezelelo se-dehydrozingerone, khetha imveliso ene-bioavailability engcono kakhulu. Ngokukhetha isongezelelo esine-bioavailability ephezulu, unokuqinisekisa ukuba umzimba wakho unokusebenzisa ngokufanelekileyo i-dehydrozingerone ngezibonelelo eziphezulu.
3. Indlela yokupheka
Qwalasela i-dehydrozingerone supplement formulations. Ezinye iimveliso zinokuqulatha ezinye izithako ezihambelana neziphumo ze-dehydrozingerone, ezifana ne-turmeric okanye ezinye i-antioxidants. Ezi zithako ze-synergistic ziphucula ukusebenza ngokupheleleyo kwesongezo. Ukongeza, qwalasela uhlobo lolongezelelo, nokuba i-capsule, umgubo, okanye ulwelo, kwaye ukhethe eyona ilungele ukhetho lwakho kunye nendlela yokuphila.
4. Isidima sophawu
Xa ukhetha isongezelelo se-dehydrozingerone, qwalasela igama le-brand. Khangela inkampani enerekhodi yokuvelisa umgangatho ophezulu, izongezo ezisebenzayo. Phanda iindlela zokwenziwa kwebrendi, ukufumana isithako, kunye nokuzinikela kumgangatho. Ukufunda uphononongo lwabathengi kunye nokufuna iingcebiso kubasebenzi bezempilo kunokubonelela ngemibono exabisekileyo kwisidima sophawu lwakho.
5. Ukungafihli kunye novavanyo
Khetha izongezo ze-dehydrozingerone kwiinkampani ezinokukhangela okusekuhleni kunye nezenzo zovavanyo. Jonga iimveliso ezivavanyiweyo ziilebhu zomntu wesithathu ukucoceka, amandla, kunye nokhuseleko. Ukungafihli kwinkqubo yokuvelisa kunye nokuvavanya kubonisa ukuzibophelela kumgangatho kwaye kuqinisekisa ukuthembeka kwesongezo.
6. Iinjongo zempilo
Xa ukhetha isongezelelo se-dehydrozingerone, qwalasela iinjongo zakho ezithile zempilo kunye nempilo. Nokuba ujonge ukuxhasa impilo edibeneyo, ukunciphisa ukudumba, okanye ukuphucula impilo yonke, khetha isongezelelo esihambelana neemfuno zakho. Ezinye iimveliso zinokuthi zenziwe ngeenjongo ezithile, ezinjengokuxhasa umsebenzi wokuqonda okanye ukukhuthaza impilo yokugaya ukutya, ngoko ke kubalulekile ukukhetha isongezelelo esihambelana neenjongo zakho.
7. Dibana nengcali yezempilo
Ngaphambi kokuba ungeze naziphi na izongezo ezitsha kwindlela yakho yezempilo, kuyacetyiswa ukuba udibane nochwepheshe bezempilo, ngakumbi ukuba unayo nayiphi na imeko yezempilo ephantsi okanye uthatha amayeza. Ingcali yezempilo inokubonelela ngeengcebiso ezenzelwe umntu ngokusekwe kwimeko yempilo yakho kwaye akuncede uqonde ukuba yeyiphi i-dehydrozingerone isongezelelo esilungele iimfuno zakho.
I-Suzhou Myland Pharm & Nutrition Inc. ibandakanyeke kwishishini lokongezelela isondlo ukususela ngo-1992. Yinkampani yokuqala e-China ukuphuhlisa nokuthengisa isicatshulwa sembewu yomdiliya.
Iminyaka engama-30 yamava kwaye iqhutywa bubuchwephesha obuphezulu kunye nesicwangciso se-R&D esiphuculwe kakhulu, inkampani iphuhlise uluhlu lweemveliso ezikhuphisanayo kwaye ibe sisongezelelo sesayensi yobomi, ukuhlanganiswa kwesiko kunye nenkampani yeenkonzo zokuvelisa.
Ukongeza, iSuzhou Myland Pharm & Nutrition Inc. ikwangumvelisi obhalisiweyo we-FDA. Izixhobo ze-R&D zenkampani, izixhobo zemveliso, kunye nezixhobo zohlalutyo zezanamhlanje kwaye zinemisebenzi emininzi, kwaye zinokuvelisa iikhemikhali ukusuka kwimilligrams ukuya kwiitoni kwisikali, kwaye zithobela imigangatho ye-ISO 9001 kunye neenkcukacha zemveliso ye-GMP. .
Umbuzo: Yintoni i-Dehydrozingerone kwaye igalelo njani kwimpilo epheleleyo?
A: I-Dehydrozingerone yikhompawundi yendalo efunyenwe kwijinja eye yafundiswa ngenxa yeenzuzo zayo zempilo, kubandakanywa ne-anti-inflammatory, izakhiwo ze-antioxidant, ezinegalelo kwimpilo epheleleyo.
Umbuzo: I-Dehydrozingerone inokuthi ifakwe njani kwirejimeni yezempilo epheleleyo?
A: I-Dehydrozingerone inokufakwa kwirejimeni yezempilo egcweleyo ngokusebenzisa imithombo yokutya efana nengcambu ye-ginger, kunye ne-supplement kunye nezicelo zezihloko ezinokuthi zibe nemiphumo yokukhuthaza impilo.
Umbuzo: I-Dehydrozingerone inokuxhasa njani ukusebenza komzimba kunye nokuphila kakuhle?
A: Iipropathi ze-Dehydrozingerone ezichasayo kunye ne-antioxidant zinokuxhasa ukusebenza komzimba kunye nokuphila kakuhle ngokunceda ukunciphisa uxinzelelo lwe-oxidative kunye nokuvuvukala emzimbeni.
Umbuzo: Zeziphi iifom i-Dehydrozingerone ekhoyo ukuze isetyenziswe okanye isetyenziswe?
A: I-Dehydrozingerone ifumaneka kwiifom zokutya ezifana nengcambu ye-ginger, kunye neefom ezigxininisiweyo ezifana nezongezelelo, izicatshulwa, kunye namalungiselelo asemgangathweni kwizicelo ezahlukeneyo zempilo.
Umbuzo: I-Dehydrozingerone ithelekisa njani nezinye iikhompawundi zendalo ekukhuthazeni impilo epheleleyo?
A: I-Dehydrozingerone ikwabelana ngokufana nezinye izinto zendalo ezifana ne-curcumin kunye ne-resveratrol ekukwazini kwayo ukuxhasa impilo epheleleyo ngokusebenzisa i-anti-inflammatory and antioxidant properties.
Ukuziphendulela: Eli nqaku lelolwazi ngokubanzi kuphela kwaye akufanele lithathwe njengeliphi na icebiso lonyango. Olunye ulwazi lweposti yebhlog luvela kwi-Intanethi kwaye alunamsebenzi. Le webhusayithi inoxanduva kuphela lokuhlela, ukufomatha kunye nokuhlela amanqaku. Injongo yokudlulisa ulwazi olongezelelekileyo ayithethi ukuba uyavumelana neembono zayo okanye uqinisekise ubunyani bomxholo wayo. Soloko udibana nengcali yezempilo ngaphambi kokuba usebenzise naziphi na izongezo okanye wenze utshintsho kwirejimeni yokhathalelo lwempilo.
Ixesha lokuposa: Apr-09-2024
