Isakhono sokuqonda sibhekisela kubuchule bomntu bokucwangcisa ulwazi, ukukhumbula, ukufunda, ukuqonda nokusombulula iingxaki. Kuyinto ebalulekileyo kwaye ibalulekile ukuba umntu aphumelele emsebenzini nasebomini. Impembelelo yendlela yokuphucula amandla okuqonda kuneempembelelo ezibalulekileyo kwimpumelelo yomntu kunye nokuphila kakuhle.
Kweli xesha lolwazi, kufuneka sifumane ulwazi oluninzi yonke imihla. Ingqondo ayifuni nje ukufumana ulwazi, kodwa kunye nokusebenza kunye nokurekhoda ulwazi. Ngaphantsi komthwalo onjalo womsebenzi oqinileyo, kuyimfuneko ukuphucula amandla okuqonda kwengqondo. Ukuphuculwa kwengqondo kunokunceda abantu baphucule imemori, ixesha elifutshane kunye nexesha elide. Ukwazi ngcono ukukhumbula kwaye ukhumbule ulwazi, ukuphucula ukufunda kunye nemveliso.
Ngokwembono yenzululwazi, amandla okuqonda yingcamango ezinzileyo, kodwa uphando lubonisa ukuba abantu banokuphucula amandla abo okuqonda ngokusebenzisa izicwangciso ezithile kunye noqeqesho. Oku kubalulekile kuba kuthetha ukuba asinakugwetyelwa ukuba sibe nobuchule obuthile bokuqonda, kodwa sinokubuphucula ngenkuthalo ngezenzo zokuqonda.
Ke, yintoni kanye kanye iPramiracetam? I-Pramiracetam yi-synthetic compound eyeyentsapho ye-racemates. I-Pramiracetam yaphuhliswa kwi-1970 kwaye ifundwe ngokubanzi kwiipropati zayo zokuphucula ukuqonda. Kukholelwa ukuba isebenza ngokuvuselela i-receptors ethile kwingqondo ehambelana neenkqubo zokufunda kunye nememori, ngaloo ndlela iphucula umsebenzi wokuqonda jikelele.
I-Pramiracetam iphucula ukubunjwa kwememori kunye nokufunyanwa. Izifundo zibonise ukuba iPramiracetaminokuphucula kakhulu inkumbulo yexesha elifutshane kunye neyexesha elide.Oku kuluncedo ngakumbi kubafundi nakubantu abajonge ukuphucula ubuchule babo bokuqonda ngokupheleleyo.
Kwakhona kuphucula ukugxila kunye nokugxila. Abasebenzisi abaninzi baxela ukuba i-Pramiracetam ibanceda bahlale bephaphile kwaye begxininise ixesha elide, okwenza kube yinto efanelekileyo kubantu abafuna ukugxila kakhulu emsebenzini okanye esikolweni.
Kuye kwaxelwa ukuba kuphuculwe amandla omntu okucinga ngokucacileyo, kusetyenzwa ngolwazi ngokukhawuleza, kunye nokwenza unxibelelwano olunengqiqo. Ezi ziphumo zinokuthi zibangelwa yimpembelelo yePramiracetam kwi-acetylcholine receptors kwingqondo, i-neurotransmitter edlala indima ebalulekileyo kwiinkqubo zokuqonda.
Funda malunga nePramiracetam:
I-Pramiracetam i-synthetic compound evela kwintsapho ye-racemate eyaziwayo ngeempawu zayo zokuphucula ingqondo. Ithathwa ngokubanzi njengenye yeyona nootropics inamandla kwaye inamandla, eyenzelwe ukuphucula inkumbulo, ukugxininiswa, kunye nomsebenzi wokuqonda jikelele.
Ukusebenza kunye neeNzuzo:
Izifundo ezininzi ziye zavavanya ukusebenza kwePramiracetam, zigxininisa iinzuzo zayo zengqondo. Uphononongo olubalaseleyo olupapashwe kwi-Journal ye-Psychopharmacology yabika ukuba i-Pramiracetam iphucule imemori nokufunda kubantu abaphilileyo. Abathathi-nxaxheba baphathwa ngePramiracetam babonise ukuphuculwa okuphawulekayo kwimisebenzi yokukhumbula, ukucwangcisa ingqiqo, kunye nokugcinwa kwememori ixesha elide.
Ukongezelela, i-Pramiracetam icingelwa ukuba ikhulise imemori yokusebenza, eyimfuneko kwimisebenzi efuna ukugxila kunye nokukhawuleza kwengqondo. Ngokukhuthaza ukukhululwa kunye nokuthathwa kwe-acetylcholine, i-neurotransmitter ebalulekileyo kwimemori nokufunda, i-Pramiracetam ibonakaliswe ukuphucula ukusebenza kwengqondo kubantu abanokukhubazeka kwememori.
Ukongezelela, i-Pramiracetam idla ngokukhawuleza ngenxa yeempawu zayo ze-neuroprotective. Kucingelwa ukuba le nootropic iphucula ukusetyenziswa kwe-oksijini kunye ne-glucose metabolism kwingqondo, ngaloo ndlela iphucula impilo yengqondo kunye nokuthintela ukuhla kwengqondo.
Inkqubo:
Indlela echanekileyo yesenzo apho iPramiracetam yenza imiphumo yokuphucula ingqondo ayiqondwa ngokupheleleyo. Nangona kunjalo, kucatshangelwa ukulawula zombini iinkqubo ze-cholinergic kunye ne-glutamatergic, zombini ezo zidlala indima ebalulekileyo ekusebenzeni kwengqondo.
Ukulawulwa kwe-Cholinergic kubandakanya ukukhululwa kunye nokuthathwa kwe-acetylcholine, i-neurotransmitter ejongene nokwakhiwa kwememori kunye nokudibanisa. Ngokwandisa ukufumaneka kwe-acetylcholine, i-Pramiracetam icingelwa ukuba ikhulise ukubonakaliswa kwe-synaptic, ngaloo ndlela ikhuthaza ukufunda okuphuculweyo kunye nememori.
Ukulawulwa kwe-Glutamate, ngakolunye uhlangothi, kuhambelana nokulawulwa kwe-neurotransmission ejabulisayo. I-Pramiracetam icingelwa ukuba ikhulise i-glutamate, ekhuthaza ukuphuculwa kwe-synaptic plasticity kunye nokusebenza kwengqondo jikelele.
Ehlabathini lokuphucula ingqondo kunye neziyobisi ze-nootropic, i-Pramiracetam kunye ne-piracetam zizinto ezimbini ezidumileyo ezihlala ziba umboniso. Ezi khompawundi zezeqela lamachiza okwenziwa aziwa ngokuba yi-racemates, aziwa ngokuba neziphumo zazo zokuphucula ingqondo. Zombini i-Pramiracetam kunye ne-piracetam ziziyobisi ze-nootropic ezikhuthaza ukusebenza kwengqondo, ukuphucula imemori, ukuphucula ukugxila, kunye nokuphucula ukusebenza kwengqondo jikelele. Nangona kunjalo, ngaphandle kokufana, kukho umahluko othile phakathi kwezi zinto zimbini.
1. Ukwakheka kweekhemikhali:
I-Piracetam, i-foreur yazo zonke iziyobisi zobuhlanga, yafunyanwa kwi-1960s. Iqukethe isakhiwo se-pyrrolidone kwaye lilungu elisisiseko lentsapho ye-racemate. I-Pramiracetam, ngakolunye uhlangothi, i-derivative ye-piracetam kunye neqela le-dipropan-2-ylaminoethyl elongezelelweyo kwisakhiwo sayo. Olu tshintsho luncinci lwenza iPramiracetam isebenze ngakumbi kunepiracetam.
2. Ukusebenza kunye nomthamo:
Ngokumalunga namandla, iPramiracetam iphezulu kunePiracetam. Kuqikelelwa ukuba inamandla aphindwe ka-10 ukuya kwangama-30 kunowandulelayo. Ngenxa yamandla ayo aphuculweyo, iidosi eziphantsi kakhulu ziyafuneka kwiPramiracetam xa kuthelekiswa nepiracetam.
3. Indlela yokwenza:
I-Pramiracetam kunye ne-piracetam zombini zisebenza ngokuchaphazela inkqubo ye-cholinergic kwingqondo. Zichaphazela imveliso kunye nomsebenzi we-neurotransmitters ezifana ne-acetylcholine, edlala indima ebalulekileyo kwimemori, ukufunda kunye nezinye iinkqubo zokuqonda. Nangona kunjalo, i-Pramiracetam icingelwa ukuba ibe nefuthe elithe ngqo kwi-high-affinity choline uptake (HACU) kwi-hippocampus, ummandla wengqondo ojongene nokubunjwa kwememori kunye nokubuyiswa. Esi senzo sikhethekileyo sePramiracetam senza ukuba sisebenze ngakumbi ekwandiseni inkumbulo.
4. Iinzuzo zengqondo:
Zombini iPramiracetam kunye nepiracetam zineenzuzo ezininzi xa kufikwa kuphuculo lwengqondo. I-piracetam idla ngokuthandwa ngenxa yokukwazi kwayo ukuphucula imemori, ukugxininiswa kunye nokugxila. Ikwaziwa ngokuphucula ukusebenza kwengqondo iyonke, iyenza ilungele abantu abajonge ukonyusa ukusebenza kwabo kwengqondo kukonke. I-Pramiracetam, ngakolunye uhlangothi, iyasebenza ngokukodwa ekuphuculeni imemori yexesha elide, ukuphucula ukufundwa kwendawo, kunye nokwandisa uxinzelelo.
5. Iziphumo ebezinokubakho:
I-Pramiracetam kunye ne-piracetam ngokuqhelekileyo zinyamezelwa kakuhle kunye nesiganeko esiphantsi semiphumo emibi. Nangona kunjalo, iimpendulo zomntu ngamnye zinokwahluka. Iziphumo eziqhelekileyo ezinokuthi zenzeke ziquka intloko, iingxaki zesisu, ukwesaba, kunye nesiyezi. Ezi ziphumo zihlala zithambile kwaye zethutyana, ziyancipha njengoko umzimba ulungelelanisa into.
Xa kuziwa kwi-dosage yePramiracetam, kufuneka kugxininiswe ukuba i-chemistry yomzimba womntu ngamnye kunye nokunyamezela kunokwahluka. Ke ngoko, idosi inokwahluka ngokweemfuno kunye neenjongo zomntu ngamnye. Ngokubanzi, idosi eqhelekileyo yemihla ngemihla yePramiracetam isuka kwi-500 ukuya kwi-1,200 mg ihlulwe ibe ngamadosi amabini okanye amathathu yonke imini.
Kucetyiswa ukuba uqale ngedosi ephantsi kakhulu kwaye unyuse ngokuthe ngcembe ukuba kuyimfuneko. Kwaye uvavanye impendulo yomzimba wakho. Ukuba akukho siphumo sibonakalayo sibonwa, idosi inokuhlengahlengiswa ukuya phezulu ukuvumela ixesha lomzimba wakho ukuba uhlengahlengise kutshintsho lwedosi nganye.
imiphumela:
Nangona i-Pramiracetam ixhatshazwa kakuhle, umntu kufuneka aqaphele imiphumo emibi. Iziphumo ezibikiweyo zePramiracetam zincinci kwaye zinqabile, kwaye ngokuqhelekileyo zixazulula emva kokuyeka i-compound. Ezi ziphumo bezingalindelekanga zinokubandakanya:
●Intloko ebuhlungu: Intloko ebuhlungu yeyona nto ixhaphakileyo ehambelana nokusetyenziswa kwePramiracetam. Ukwandisa i-choline yokutya ngokusebenzisa imithombo yokutya efana namaqanda okanye ukusebenzisa izongezo ze-choline kunokunceda ukunciphisa le mpembelelo yecala.
●Ukuphazamiseka kwesisu: Abanye abasebenzisi baye baxela iimpawu zokugaya ezifana nesicaphucaphu, isisu esibuhlungu, okanye isifo sohudo. Ukuqinisekisa ukuba uthatha iPramiracetam kunye nokutya kunokunceda ukunciphisa le miphumo.
●Ukuphazamiseka kokulala: I-Pramiracetam inokubangela ukuphazamiseka kokulala njengokungalali xa ithathwa kamva emini. Ukuze ugweme oku, kucetyiswa ukuba uthathe i-praracetam ekuqaleni kwemini okanye kusasa.
●Ukuxhalaba okanye uxinzelelo: Kwiimeko ezinqabileyo, umntu unokufumana ixhala elongezelelweyo okanye uxinzelelo. Ukuba ufumana ezi mpawu, kuyacetyiswa ukuba uyeke ukusebenzisa kwaye udibane nochwepheshe bezempilo.
Umbuzo: Kuthatha ixesha elingakanani ukufumana iziphumo zePramiracetam?
A: Ukuqala kweempembelelo zePramiracetam kunokuhluka kumntu kumntu. Ngelixa abanye abantu banokuqala ukuqaphela izibonelelo zayo kwiiyure ezimbalwa, abanye banokuthatha iintsuku ezimbalwa zokusetyenziswa rhoqo ukuze bafumane uphuculo olubonakalayo ekusebenzeni kwengqondo.
Umbuzo: Ngaba iPramiracetam ikhuselekile ukuba isetyenziswe?
A: I-Pramiracetam ngokuqhelekileyo ithathwa njengekhuselekile ukusetyenziswa xa ithathwa kwi-dosage ecetyiswayo. Nangona kunjalo, njengaso nasiphi na isongezelelo okanye iyeza, kuhlala kucetyiswa ukuba udibane nengcali yezempilo ngaphambi kokuba uqalise ukusetyenziswa kwayo, ngakumbi ukuba unayo nayiphi na imeko yezonyango okanye uthatha amanye amayeza.
Ukuziphendulela: Eli nqaku lenzelwe iinjongo zolwazi kuphela kwaye akufanele lithathwe njengengcebiso yezonyango. Soloko udibana nengcali yezempilo phambi kokuba usebenzise naziphi na izongezo okanye utshintshe irejimeni yokhathalelo lwempilo yakho.
Ixesha lokuposa: Aug-11-2023
