Kusukelo lwendlela yokuphila esempilweni, sisoloko sifuna ukuphucula impilo-ntle yethu ngeendlela ezahlukeneyo. Ukudumba yimpendulo yendalo yomzimba ukuze uzikhusele ekwenzakaleni kwaye ukhuthaze ukuphiliswa. Nangona kunjalo, ukuvuvukala okungapheliyo kunokukhokelela kwiingxaki ezahlukeneyo zempilo, kwaye izongezo ezichasayo ziye zaboniswa ukunciphisa ukuvuvukala emzimbeni. Zifumaneka kukutya, imifuno, kunye nezinye izongezo zokutya. Ukusuka ekunciphiseni ukuvuvukala ukuya ekuxhaseni amajoni ethu omzimba, izongezo ezichasene nokudumba zithandwa ngendima yazo enokubakho ekukhuthazeni impilo yonke. Ngelixa izongezo ezichasene nokudumba zinokuba luncedo kwindlela yokuphila enempilo, kubalulekile ukugxila ekutyeni ukutya okunesondlo kunye nokwenza umthambo rhoqo.
Impendulo yokudumba yindlela yokuzikhusela yendalo yomzimba xa ibonakaliswe kwizinto eziyingozi ezifana neentsholongwane, iiseli ezonakeleyo, okanye izinto ezicaphukisayo. Le nkqubo ibalulekileyo ye-physiological inceda ukukhusela nokuphilisa umzimba kwingozi okanye usulelo. Nangona ukudumba kudla ngokunxulunyaniswa nobubomvu, ubushushu, ukudumba, kunye neentlungu, yinxalenye ebalulekileyo yenkqubo yokuphilisa.
Xa kukho ukwenzakala okanye usulelo, inkqubo yomzimba yokuzikhusela ikhupha iindidi ngeendidi zeekhemikhali kunye neeseli ezisebenzisanayo ukulwa nomhlaseli. Ezi khemikhali zibangela ukuba imithwalo yegazi kwindawo echaphazelekayo ivuleke, ngaloo ndlela ikhulise ukuhamba kwegazi kwindawo yokulimala okanye ukusuleleka. Ukunyuka kwegazi kubangela ubomvu kunye nokufudumala kwindawo.
Kwangaxeshanye, imithambo yegazi ingena lula, ivumela ulwelo, iiproteni, kunye neeseli ezimhlophe zegazi ukuba zivuze kwiithishu ezijikelezileyo. Olu lwelo lwande lubangela ukudumba, okunceda ukuba ube lodwa ummandla owenzakeleyo kuze kuthintelwe ukwanda kosulelo.
Ukongeza, iiseli ezimhlophe zegazi, ngakumbi i-neutrophils kunye ne-macrophages, zitsalwa kwiindawo zokudumba. Ezi seli ziginya kwaye zitshabalalise abahlaseli bamanye amazwe, zisusa iiseli ezifileyo, kwaye ziqalise iinkqubo zokulungisa izicwili. Abalamli abatshisayo abafana ne-histamine kunye ne-cytokines nabo bakhululwa ngexesha lokusabela ukunyusa amandla omzimba wokumelana ne-immune stimuli.
Ngelixa ukudumba kudlala indima ebalulekileyo ekukhuseleni umzimba, kunokuba neziphumo ezibi ukuba kuba kungapheliyo okanye kugqithise. Ukuvuvukala okungapheliyo kwenzeka xa i-immune system igqithisa okanye ihluleka ukuphelisa imbangela yokuqala yokuvuvukala. Le mpendulo ye-immune eqhubekayo ingakhokelela kumonakalo wezicubu kunye nokuphuhliswa kwezifo ezahlukahlukeneyo ezingapheliyo, ezibandakanya i-rheumatoid arthritis, i-asthma, kunye nesifo sesibindi esivuthayo.
Ke kwimpilo engcono, ukuchasana nokudumba kubalulekile, ke yintoni i-anti-inflammation? I-Anti-inflammatory ibhekisela kwizinto okanye iziyobisi ezinciphisa ukuvuvukala kunye nokunciphisa iimpawu zayo. Ezi zinto zisebenza ngokujolisa iimolekyuli ezithile kunye neendlela ezibandakanyekayo kwimpendulo yokuvuvukala. Zifumaneka kumachiza, amayeza endalo, kunye nokutya okuthile, kwaye zinokongezwa kwisidlo kunye ne-anti-inflammatory supplements.
Ukongeza kokugcina ukutya okunempilo kunye nokwenza utshintsho kwindlela yokuphila, abantu abaninzi baphendukela kwii-anti-inflammatory supplements ukuze balwe nokuvutha ngcono. Izongezo ezichasayo zinika indlela yendalo kunye nebanzi yokulawula ukuvuvukala okungapheliyo. Ngokubandakanya ezi zongezo kwindlela yakho yemihla ngemihla, unokunciphisa ukuvuvukala, ukukhulula intlungu, ukuphucula ukusebenza komzimba, kunye nokuphucula impilo yonke.
Izongezo ezichasayo zibandakanya iintlobo ezahlukeneyo zeemveliso zendalo kunye nezongezo zokutya ezineempawu ezinamandla ezichasayo. Ziza ngeendlela ezininzi, kubandakanywa iipilisi, iipilisi, umgubo, kunye nolwelo. Ngokujolisa kwiingcambu ezibangela ukudumba, ezi zongezelelo zibonelela ngeenzuzo ezininzi zempilo, kubandakanya ukunciphisa iintlungu kunye nokudumba, ukuphucula impilo edibeneyo, ukulawula amanqanaba eswekile yegazi, ukuphucula ukusebenza kwengqondo, kunye nokukhuthaza ukuxhaswa kwamajoni omzimba. Ukubandakanya ezi zongezo kwindlela yakho yemihla ngemihla kunokunceda ukukhuthaza impilo yonke kunye nokunciphisa umngcipheko wezifo ezingapheliyo ezinxulumene nokuvuvukala.
Ukuvuvukala yimpendulo yendalo eyenzeka emizimbeni yethu njengendlela yokuthintela ukulimala, usulelo, okanye izifo. Nangona kunjalo, xa ukudumba kuba yinto engapheliyo, kunokukhokelela kwiingxaki ezinzulu zempilo. Ngethamsanqa, kukho i-anti-inflammatory agents ezinokukunceda ukunciphisa ukuvuvukala nokukhusela umonakalo wexesha elide kwimpilo yethu.
●Ukunciphisa ukuvuvukala kunye neentlungu: Ukuvuvukala okuninzi, njengentlungu edibeneyo kunye nobuhlungu bemisipha, ihamba kunye nokungahambi kakuhle. Izongezelelo ezichasayo zinokubonelela ngeentlungu zendalo ngokuthintela iimolekyuli ezivuthayo kunye neendlela, ukunciphisa ukuvuvukala kumthombo wayo. Inokukunceda ukunciphisa iimpawu ezinxulumene nezifo ezivuthayo, ezifana ne-arthritis kunye ne-asthma.
●Ukuphucula impilo yentliziyo: Ukuvuvukala kunxulumene nezifo zentliziyo ezifana nesifo senhliziyo kunye nesifo sohlangothi. Ngokunciphisa ukuvuvukala, izinto ezichasayo zinokunceda ukunciphisa umngcipheko wezi zifo. Uphando lubonisa ukuba ukusetyenziswa rhoqo kweziyobisi ezichasayo kunokunciphisa amanqanaba eprotheyini ye-C-reactive, uphawu lokuvuvukala emzimbeni. Oku, kwakhona, kunokunciphisa umngcipheko wesifo senhliziyo kunye nokuphucula impilo yonke ye-cardiovascular health.
●Ukuphucula impilo yengqondo kunye nokusebenza kwengqondo: Ukuvuvukala okungapheliyo kudibene nezifo ze-neurodeergenerative ezifana ne-Alzheimer's kunye ne-Parkinson. Ngokunciphisa ukuvuvukala kwingqondo, ii-anti-inflammatory agents zinokucothisa ukuqhubeka kwezi zifo kwaye zikhuthaze impilo yengqondo. Ukongeza, izifundo zifumene unxibelelwano phakathi kokudumba kunye nokuphazamiseka kwempilo yengqondo njengokudakumba kunye noxinzelelo. Ngokunciphisa ukuvuvukala, izinto ezichasayo zinokuba nefuthe elihle kwimpilo yengqondo.
●Ukuphucula ukusebenza kwe-immune: Iziyobisi ezichasayo zidlala indima ebalulekileyo ekuphatheni izifo ezizimele. Izifo ezizilawulayo zenzeka xa inkqubo yomzimba yokuzikhusela ihlasela izicubu zayo ngempazamo. Izifo ezininzi ze-autoimmune, ezifana ne-rheumatoid arthritis kunye ne-lupus, zibandakanya ukuvuvukala okungapheliyo. Ngokunciphisa ukuvuvukala, izinto ezichasayo zinokunceda ukukhulula iimpawu kunye nokuphucula umgangatho wobomi kubantu abanezi meko.
1. I-Turmeric / i-Curcumin
Eyaziwayo ngenxa yeempawu zayo ezinamandla ezichasayo, i-turmeric, okanye i-curcumin yayo esebenzayo, iyisongezelelo esinamandla sendalo. Izifundo ezininzi zibonise ukuba i-curcumin iyasebenza ekulweni nokuvuvukala okungapheliyo. Inceda ukuthintela ukuveliswa kwamanqaku avuthayo emzimbeni kwaye ineempawu ze-antioxidant. Ukongezelela, i-curcumin idibaniswe nokuphucula ukugaya kunye nokusebenza kwengqondo okuphuculweyo.
2. Isicatshulwa seti eluhlaza
Iti eluhlaza kudala isaziwa ngenxa yeenzuzo zayo ezininzi zempilo, kwaye izicatshulwa zayo ziye zanda kakhulu kwiminyaka yakutshanje. Iikhompawundi eziphambili ezisebenzayo ezibizwa ngokuba yi-catechins zineempembelelo ezinamandla ezichasayo. I-EGCG, eyona catechin ininzi kwiti eluhlaza, icinezela ukuvuvukala kunye nokunciphisa uxinzelelo lwe-oxidative emzimbeni. Isicatshulwa seti eluhlaza sinokunceda ekulawuleni ubunzima, ukuxhasa ukusebenza kwengqondo, kunye nokunceda ukunciphisa umngcipheko wesifo esingapheliyo.
I-OEA yimolekyuli ye-lipid eyenzeka ngokwemvelo ephuma kwintsapho ye-N-acylethanolamine (NAE). Idityaniswe kwizicubu ezahlukeneyo emzimbeni wethu, ngakumbi ekuphenduleni ukuvuvukala kunye neentlungu. Uphando lubonisa ukuba i-OEA inokuthintela ukuveliswa kweemolekyuli ze-pro-inflammatory ezidlala indima ebalulekileyo ekuqaliseni nasekuqhubekeni kokuvuvukala.
I-OEA ifunyenwe ukumodareyitha umsebenzi weeseli zomzimba, kuquka i-macrophages kunye ne-lymphocytes ejongene neempendulo ezivuthayo. Ngokunciphisa ukusebenza kunye nokufuduka kwezi seli zomzimba ukuya kwiindawo zokukrala, i-OEA inokunceda ukunciphisa ukuveliswa kwabalamli abavuthayo, ngaloo ndlela ukunciphisa iimpawu ezinxulumene nokudumba okungapheliyo.
Ukongezelela, i-OEA yenza i-anti-inflammatory effects ngokuvula i-receptors ethile, njenge-peroxisome proliferator-activated receptor-α (PPAR-α) kunye ne-receptor yesikhashana enokubakho i-vanilloid uhlobo lwe-1 (TRPV1) iziteshi. Ezi receptor ziyaziwa ngokulawula ukuvuvukala kunye neendlela zentlungu emizimbeni yethu. Ngokusebenzisa la ma-receptors, i-OEA inqanda ukuveliswa kweemolekyuli ezivuthayo kunye nokuthintela ukuhanjiswa kweempawu zentlungu, ukubonelela ngeenzuzo ezimbini zokuvuvukala okungapheliyo okuhambelana neentlungu.
Okubangel 'umdla kukuba, i-OEA ikwabonakaliswe ukuba ine-gastrointestinal (GI) anti-inflammatory properties. Ukuvuvukala okungapheliyo kwendlela yesisu yingxaki eqhelekileyo engakhokelela kwiimeko ezifana nesifo sofuba (IBD). Uphando lubonisa ukuba i-OEA inokunciphisa ukudumba kwamathumbu ngokumodareyitha ukusebenza kweeseli zomzimba kunye nokukhuthaza ukulungiswa kwezicubu zesisu.
Ukongezelela, i-OEA ifunyenwe inempembelelo yokuthintela ekusebenziseni i-nuclear factor κB (NF-κB), i-molecule engundoqo yomqondiso echaphazelekayo ekulawuleni ukuvuvukala. I-NF-κB iyaziwa ngokukhuthaza ukubonakaliswa kwezakhi zofuzo ezifakwe kwi-pro-inflammatory factor. Ngokuthintela ukusebenza kwe-NF-κB, i-OEA inokunciphisa ukuveliswa kunye nokukhululwa kwezi zinto ezivuthayo, ngaloo ndlela zivimbela ukuvuvukala okungapheliyo.
Umbuzo:Ziziphi izongezo ezichasene nokudumba?
A: Izongezelelo ezichasayo zizinto zendalo ezinceda ukunciphisa ukuvuvukala emzimbeni. Zinokubandakanya iivithamini ezahlukeneyo, iiminerali, kunye nezityalo ezisekelwe kwizityalo eziye zaboniswa ukuba zinezixhobo ezichasayo.
Umbuzo: Zisebenza njani izongezo ezichasene nokudumba?
A: Izongezelelo ezichasayo zisebenza ngokunciphisa ukuveliswa kweekhompawundi ezivuthayo emzimbeni kunye nokukhuthaza ukuveliswa kweekhompawundi ezichasayo. Oku kunceda ukunciphisa ukudumba kwaye kunokubonelela ngesiqabu kwiimeko ezinxulumene nokudumba okungapheliyo.
Ukuziphendulela: Eli nqaku lelolwazi ngokubanzi kuphela kwaye akufanele lithathwe njengeliphi na icebiso lonyango. Olunye ulwazi lweposti yebhlog luvela kwi-Intanethi kwaye alunamsebenzi. Le webhusayithi inoxanduva kuphela lokuhlela, ukufomatha kunye nokuhlela amanqaku. Injongo yokudlulisa ulwazi olongezelelekileyo ayithethi ukuba uyavumelana neembono zayo okanye uqinisekise ubunyani bomxholo wayo. Soloko udibana nengcali yezempilo ngaphambi kokuba usebenzise naziphi na izongezo okanye wenze utshintsho kwirejimeni yokhathalelo lwempilo.
Ixesha lokuposa: Dec-06-2023
