I-Spermidine, i-activator enamandla yenkqubo yokuhlaziywa kweeseli, ithathwa ngokubanzi "njengomthombo wobutsha." Le micronutrient yikhemikhali i-polyamine kwaye iveliswa ikakhulu yintsholongwane yamathumbu emizimbeni yethu. Ukongeza, i-spermidine inokufunxwa ngumzimba ngokutya. Uphando lubonisa ukuba i-spermidine, nokuba ibonelelwe ngaphandle okanye iveliswe yi-microbiome yomzimba, isebenza ngendlela ehambelanayo.
Ukugxininiswa kwe-spermidine engapheliyo kunokuncipha ngokukhula, kwaye kunokubakho unxibelelwano phakathi koku kunye nokuwohloka okunxulumene neminyaka ekusebenzeni komzimba. I-Spermidine ifumaneka kukutya okuninzi, kunye ne-grapefruit yenye yezona zinto zityebileyo zokutya okune-spermidine. Olunye uphando lufumene ukuba i-spermidine ayicothi nje inkqubo yokuguga kodwa inokukhuthaza impilo kunye nokuphila ixesha elide. Ezi ziphumo zenza i-spermidine enye yezihloko ezishushu zophando lwangoku.
Kwizinto eziphilayo, ukugxilwa kwezicubu zespermidineukwehla ngendlela exhomekeke kwiminyaka yobudala; kunjalo, abasempilweni 90- kunye centenarians amanqanaba spermidine kufutshane nalawo abantu abaselula (abaphakathi-ababudala). Uphononongo lwe-epidemiological luchaze ubudlelwane obuhle phakathi kwe-spermidine intake kunye nempilo yabantu. Abathathi-nxaxheba be-829 abaneminyaka engama-45-84 ubudala balandelwa iminyaka eyi-15. I-Spermidine intake iqikelelwe yonke iminyaka ye-5 ngokusekelwe kwi-questionnaire yokutya rhoqo. Uphononongo lufumene ukuba abantu abathatha i-spermidine ephezulu banciphise amazinga omhlaza kunye nesifo senhliziyo kwaye banxulunyaniswa nokuphuculwa kokusinda.
◆Isixhobo sokuchasa ukuguga
Ngo-2023, i-"Cell" yapapasha inqaku ukuba kukho iimpawu ze-12 zokuguga, kubandakanywa ukungazinzi kwe-genome, i-telomere attrition, utshintsho lwe-epigenetic, ukulahleka kweprotheyini ye-homeostasis, ukungakwazi kwe-macroautophagy, ukuphazamiseka kokubona izondlo, ukungasebenzi kwe-mitochondrial, kunye ne-cell senescence. Ukudinwa kweeseli ze-stem, unxibelelwano olutshintshileyo lwe-intercellular, ukuvuvukala okungapheliyo, kunye ne-dysbiosis.
● Ukuqaliswa kwe-autophagy
Okwangoku, ukufakwa kwe-autophagy kuthathwa njengendlela ephambili apho i-spermidine ilibazisa ukuguga. Uphononongo lufumene ukuba i-spermidine ibangela i-dephosphorylation yeprotein kinase B, ibangela ukuthuthwa kwe-forkhead box transcription factor O (FoxO) kwi-nucleus, okukhokelela ekunyuseni ukukhutshelwa kwe-FoxO target gene autophagy microtubule-ehambelana ne-protein light chain 3 (LC3) ). Ukukhuthaza i-autophagy.
Ukongeza, i-spermidine ifunyenwe ukunceda ukulibazisa ukuguga kweeseli zentsholongwane yabasetyhini ezibangelwa kuxinzelelo lwe-oxidative kunye nokugcina ukuchuma kwabasetyhini. Uphononongo lweklinikhi oluthatha unyaka wonke lufumanise ukuba amanqanaba amadlozi aphuculwe kumavolontiya angamadoda asempilweni xa besondliwa ngespermidine; kuphononongo luka-2022, uphononongo lujonge kwizigulane ezingama-377 ze-acute myocardial infarction (AMI). bafumanisa ukuba abantu abanamanqanaba aphezulu e-spermidine egazini labo babeneengxaki ezingcono zokusinda kunezigulane zesifo senhliziyo ezinamazinga aphantsi e-spermidine; Ijenali yowama-2021 yafumanisa ukuba ukutya okuphezulu kwe-spermidine Kukho ikhonkco phakathi kwedosi kunye nomngcipheko oncitshisiweyo wokuphazamiseka kwengqondo ebantwini, inceda kakhulu ingqondo ekuphuculeni ukuqonda kunye nokuthintela izifo zobuchopho eziqhelekileyo ezinxulumene nobudala.
●Libazise ukuguga kwe-telomere
Ukwaluphala kubangela uninzi lweemolekyuli, iiseli, kunye nokuwohloka komzimba, kubandakanya ukungaphumeleli kwentliziyo, i-neurodegeneration, i-metabolic maladaptation, i-telomere attrition, kunye nokulahleka kweenwele. Kuyathakazelisa ukuba kwinqanaba le-molecular, ukukwazi ukwenza i-autophagy (inkqubo ephambili yesenzo se-spermidine) iyancipha ngokuguga, into ekhoyo kwiimodeli ezininzi zezinto eziphilayo kwaye kucingelwa ukuba ihambelana ngokusondeleyo nokuguga. .
● I-Antioxidant kunye ne-anti-inflammatory effects
Uxinzelelo lwe-oxidative yinto ebalulekileyo ekhokelela ekugugeni kweeseli kunye nomonakalo. I-Spermidine ineempawu ze-antioxidant. Abaphandi bondla iimpuku exogenous spermidine iinyanga ezintathu kwaye babona utshintsho kwi-ovari. Emva konyango lwe-spermidine, iqela, inani le-atrophic follicles (i-follicles ehlanjululweyo) yancitshiswa kakhulu, umsebenzi we-antioxidant we-enzyme yanda, kwaye amanqanaba e-malondialdehyde (MDA) ayancipha, anokunciphisa amanqanaba e-oxygen esebenzayo (ROS), ebonisa ukunciphisa uxinzelelo lwe-oxidative kwi-spermidine. iqela elinyangwe .
Ukudumba okungapheliyo kubonakala kungenakuphepheka njengoko sikhula. Ukunyuka kwe-spermidine kunceda ukuvuselela ukuveliswa kwee-cytokines ezichasayo ngelixa kunciphisa ukuveliswa kwee-cytokines ezivuthayo. Uphando lwakutsha nje lubonisa ukuba i-spermidine iphinda iphucule iipropathi ezichasayo ze-macrophages.
●Nqanda ukuguga kweeseli
I-Spermidine ikhuthaza umsebenzi we-mitochondrial kunye nokuveliswa kwe-keratin kwiiseli ze-epithelial stem, ngokuqhubekayo iqinisekisa ukuvuselelwa kwemisipha kunye neenwele.
I-Spermidineyikhompawundi yepolyamine ngokwendalo efumaneka kwizinto eziphilayo. Ekubeni i-polyamine compound, inamaqela amaninzi e-amino (-NH2). La maqela anika into eyodwa kwaye iyimfuneko Incasa yegama.
Kungenxa yokuba la maqela e-amino anokunxibelelana neentlobo ngeentlobo ze-biomolecules kwaye enze imisebenzi yawo ye-physiological ngaphakathi kweeseli. Ngokomzekelo, idlala indima ebalulekileyo ekukhuleni kweeseli, ukwahlula, ukulawulwa kofuzo, kunye nokuchasana nokuguga.
Anti ukuguga
Inqanaba le-Spermidine luphawu olubonisa iqondo lokuguga komzimba. Njengoko umzimba uguga, umxholo we-spermidine emzimbeni nawo uyancipha. Uphononongo lubonise ukuba i-spermidine inokulibazisa ukuguga kweeseli ezifana neeseli zegwele kunye neeseli ze-mammalian, kunye nokwandisa ubomi bezinto eziphilayo ze-invertebrate ezifana ne-Drosophila melanogaster kunye ne-Caenorhabditis elegans kunye neempuku.
Okwangoku, ukufakwa kwe-autophagy kuye kwafakazelwa ukuba yenye yeendlela eziphambili apho i-spermidine ilibazisa ukuguga kunye nokwandisa ubomi. Uphononongo lubonise ukuba emva kokukhupha iimfuza eziyimfuneko kwi-autophagy kwigwele lokuguga, i-Drosophila kunye neeseli ezanyisayo ezikhulileyo, ezi zilwanyana ziyimodeli azizange zibe nobomi obude emva konyango nge-spermidine. Ukongezelela, i-spermidine isebenza ngeendlela ezifana nokunciphisa i-histone acetylation.
I-Antioxidant
I-Spermidine inemisebenzi ebalulekileyo ye-antioxidant, kwaye inokusebenzisa iziphumo ezichasene nokuguga ngokusebenzisa iipropathi zayo ze-antioxidant. Uphononongo lubonise ukuba i-spermidine inokunciphisa kakhulu amanqanaba e-malondialdehyde oxidant kwaye yandise amanqanaba e-antioxidant enciphisa i-glutathione kwiingqondo zeegundane.
I-Spermidine supplementation nayo yaphucula umsebenzi we-electron chain chain complexes kwi-mitochondria yobuchopho obuguga, ebonisa amandla ayo e-antioxidant kwinqanaba le-mitochondrial. I-Spermidine inciphisa umonakalo kwimithambo-luvo ebangelwa kukuguga okubangelwa kuxinzelelo lwe-oxidative ngokulawula i-autophagy, amanqanaba e-antioxidant kunye nokunciphisa i-neuroinflammation.
Uphononongo lufumene ukuba i-spermidine ikhusela umonakalo weseli owenziwe yi-H2O2 ngokuthintela ukwanda kwe-Ca2 + kwiiseli ze-epithelial ze-retinal pigment.
Ukuchasana nokudumba
I-Spermidine inefuthe elihle elichasayo, kwaye indlela yayo ihambelana nokuthintela ukuveliswa kwezinto eziphazamisayo, ukukhuthaza ukuveliswa kwezinto ezichasayo, kunye nokuchaphazela i-polarization ye-macrophages.
Uphononongo lufumene ukuba i-spermidine inokunciphisa amanqanaba ezinto eziphazamisayo ezifana ne-interleukin 6 kunye ne-tumor necrosis factor kwi-serum yeegundane ezine-collagen-induced arthritis, ukwandisa inqanaba le-IL-10, inqanda i-polarization ye-M1 macrophages kwi-synovial tissue. , kunye nokunciphisa umngcipheko we-arthritis. Iiseli ze-synovial zeMouse zanda kwaye iiseli ezivuthayo zingena ngaphakathi, zibonisa iziphumo ezilungileyo ezichasayo.
Phucula ingqiqo
Njengoko iminyaka yabemi, ukuphazamiseka kwengqondo okunxulumene neminyaka kuya kuba ngumba ocinezelayo. I-Spermidine, njenge-autophagy inducer, ibonakaliswe ukuba inefuthe lokuphucula ekunciphiseni kwengqondo.
Uphando lubonisa ukuba ekugugeni kweempukane zeziqhamo, amanqanaba e-spermidine ayancipha, ahamba kunye nokuncipha kwekhono lokukhumbula. I-Spermidine supplementation eyondla iimpukane inciphisa ukukhubazeka kwememori kwiimpukane eziguga ngokuthintela utshintsho lwesakhiwo kunye nokusebenza kwintsebenzo ye-presynaptic ebangelwa amanqanaba aphezulu e-synaptic proteins kunye neeprotheni ezibophayo.
I-Spermidine ekutyeni inokudlula kumqobo wegazi-ingqondo yeempuku, inyuse ukuphefumla kwe-mitochondrial kwizicubu ze-neuron ye-mouse, kunye nokuphucula umsebenzi wokuqonda weempuku. Ngokwesiseko sovavanyo lwezilwanyana, ezinye izifundo zabantu ziye zangqina ukuba i-spermidine inxulumene ngokusondeleyo nokuqonda.
Khusela intliziyo
I-Spermidine inokukhusela impilo ye-cardiovascular kwaye ineempembelelo ezininzi ezifana nokuthintela ukuguga kwentliziyo, ukunciphisa uxinzelelo lwegazi kunye nokulibazisa ukungaphumeleli kwentliziyo. Uphononongo lubonise ukuba ukuxhaswa kwe-spermidine kunokuphucula i-autophagy ye-cardiac kunye ne-mitophagy kwiimpuku, yenze i-cardioprotective effect kunye nokulibazisa ukuguga kwentliziyo.
Kwiimpuku ezisele zikhulile, i-dietary spermidine supplementation iphucula i-elasticity yomatshini kunye nepropathi ye-metabolic ye-cardiomyocytes, ngaloo ndlela yandisa ubomi kunye nokuthintela i-hypertrophy ye-cardiac ebangelwa ubudala kunye nokuqina. Izifundo ze-Epidemiological kubantu zibonisa ukuba i-spermidine ineempembelelo ezifanayo zokukhusela kwimpilo yentliziyo yomntu. Ukutya kwe-Spermidine ekudleni komntu kuhambelana ngokungafaniyo nesifo senhliziyo. Ezi mpawu ze-spermidine zivula iindlela ezintsha zonyango lwezifo zentliziyo.
Ubume bangoku bophuhliso kunye nokusetyenziswa kwe-spermidine
I-Spermidine yi-polyamine eyenzeka ngokwemvelo. Umxholo we-physiological we-spermidine yindalo, iyasebenza, ikhuselekile kwaye ayinayo inetyhefu. Ngophando olunzulu lweziphumo zomzimba ze-spermidine, lubonise ixabiso elibalulekileyo lesicelo kwiinkalo ezininzi ezifana neyeza, ukutya kwezempilo, ezolimo, izimonyo njalo njalo.
Iyeza
I-Spermidine ineempembelelo ezahlukeneyo zomzimba ezifana nokuchasana nokuguga, ukuchasana nokuvuvukala, ukuchasana nomhlaza, kunye nokuphucula ukuqonda. Ingasetyenziselwa uthintelo kunye nonyango lwe-osteoarthritis, umonakalo weseli ye-nerve, isifo senhliziyo kunye nezinye izifo. I-Spermidine isetyenziswe kwizicelo zeklinikhi. Unyango lwezifo lunamathuba amahle ophuhliso.
Ukutya okunempilo
Ukusebenzisa "i-spermidine" kunye "nezixhobo zokutya ezisebenzayo" njengamagama angundoqo okuqhuba uphando lwedatha kwiindawo ezininzi zolwazi, iziphumo zibonisa ukuba "i-spermidine" okanye "i-spermine" ichazwa njengezinto ezisebenzayo zokutya, kwaye i-spermidine iye yathengiswa kwimarike kunye ne-spermidine. . Ukutya okunempilo kunye ne-amine njengeyona nto iphambili ekrwada.
Iimveliso zezempilo ezinxulumene ne-Spermidine zinemisebenzi eyahlukeneyo kwaye zisetyenziswa ngokubanzi kwiifom ezahlukeneyo, kubandakanywa iipilisi, iipowders kunye nezinye iifom zedosi. Inemisebenzi yokuchasana nokuguga, ukuphucula ubuthongo, kunye nokuphucula ukugonywa; i-spermidine yendalo ye powder powder ekhutshwe kwintsholongwane yengqolowa iqinisekisa ukucoceka okuphezulu kunye nomsebenzi ophezulu we-spermidine.
Ezolimo
Njengomlawuli wokukhula kwezityalo, ukusetyenziswa kwangaphandle kwe-spermidine kunokunciphisa ngokufanelekileyo umonakalo kwizityalo ezibangelwa luxinzelelo oluphezulu lwe-oxidation, ubushushu obuphantsi kunye nokubanda, i-hypoxia, ityuwa ephezulu, imbalela, izikhukhula kunye nokungena, kwaye idlala indima ebalulekileyo ekukhuleni kwezityalo. . Indima yayo ebalulekileyo kwezolimo ithe ngokuthe ngcembe yatsala ingqalelo. I-Exogenous spermidine inokunciphisa ifuthe elithintelayo loxinzelelo lwembalela ekukhuleni kwamazimba aswiti kunye nokwandisa ukunyamezela imbalela kwezithole zamazimba aswiti. Ngokusekwe kwindima ebalulekileyo ye-spermidine ekukhuleni kwesityalo, inamalungelo awodwa abenzi bokuqanjwa kwezinto ezininzi kummandla wezolimo. Uphando kunye nokuphuhlisa iimveliso zezolimo ze-spermidine kunye nokukhuthaza ukusetyenziswa kwe-spermidine kwintsimi yezolimo kubaluleke kakhulu kuphuhliso lwezolimo.
Izithambiso
I-Spermidine ine-antioxidant, i-anti-aging, kunye nokukhuthazwa kwemiphumo ye-autophagy, kwaye yinto efanelekileyo ye-cosmetic ekrwada. Okwangoku, kukho iimveliso zokhathalelo lwesikhumba ezifana ne-spermidine anti-aging cream kunye ne-spermidine essence milk kwimarike. Ukongeza, i-spermidine inamalungelo awodwa omenzi wophando kwinkalo yezithambiso kwihlabathi liphela, ebandakanya ukuqaqamba, ukuchasana nokuguga kwesikhumba, kunye nokuphuculwa kwemibimbi yobuso. Uphando olunzulu malunga nendlela yesenzo se-spermidine, ukutyebisa iifom zesicelo, kunye nokuvavanya ukhuseleko kunye nemiphumo emibi kulindeleke ukuba unikeze abathengi ngokukhuselekileyo kunye neendlela ezisebenzayo zokunakekelwa kwesikhumba.
Ebantwini, amanqanaba okujikeleza kwespermidine ziqhelekile kuluhlu olusezantsi lwe-micromolar, okunokwenzeka ngenxa yeziphumo zokutya kugxininiso lwe-spermidine ngokubanzi. Nangona bebonisa umahluko oqinileyo phakathi kwabantu. Nangona kunjalo, njengoko sikhula, inani le-spermidine kwiiseli zomzimba wethu liyehla. I-Exogenous spermidine supplementation ibuyisela utshintsho olubi olunxulumene nobudala kunye nokulibaziseka ukuguga.
● Prescine/spermine metabolism
Kwiiseli ze-mammalian, i-spermidine iveliswa kwi-precursor putrescine (ngokwayo iveliswa kwi-ornithine) okanye ngokuchithwa kwe-oxidative ye-spermine.
● I-Gut microbiota
I-intestinal microbiota ngumthombo obalulekileyo we-spermidine synthesis. Kwiimpuku, ukuxinwa kwe-spermidine kwi-lumen yamathumbu kuye kwaboniswa ukuba kuxhomekeke ngokuthe ngqo kwi-colonic microbiota.
●Imithombo yokutya
I-Spermidine efakwe ekutya inokuthatyathwa ngokukhawuleza emathunjini kwaye isasazwe emzimbeni, ngoko ukutya ukutya okuphezulu kwi-spermidine kunokunceda ukwandisa amanqanaba e-spermidine emzimbeni.
●Spermidine supplements
Iimveliso zezempilo ezinxulumene ne-Spermidine zinemisebenzi eyahlukeneyo kwaye zisetyenziswa ngokubanzi kwiifom ezahlukeneyo, kubandakanywa iipilisi, iipowders kunye nezinye iifom zedosi. Inemisebenzi yokuchasana nokuguga, ukuphucula ubuthongo, kunye nokuphucula ukugonywa; i-spermidine yendalo ye powder powder ekhutshwe kwintsholongwane yengqolowa iqinisekisa ukucoceka okuphezulu kunye nomsebenzi ophezulu we-spermidine.
Ubunyulu kunye noMgangatho
Xa kuthengwa i-spermidine powder, kubalulekile ukubeka phambili ukucoceka kunye nomgangatho. Khangela iimveliso ezenziwe kwizithako ezikumgangatho ophezulu kwaye zivavanywe ngokungqongqo ukucoceka kunye nokusebenza kakuhle. Ngokufanelekileyo, khetha iimveliso ezenziwe kwiifektri ezilandela iiNdlela eziLungileyo zokuVelisa (GMP) ukuqinisekisa umgangatho kunye nokhuseleko.
I-Bioavailability
I-Bioavailability ibhekiselele kubuchule bomzimba bokufunxa kunye nokusetyenziswa kwento ethile. Xa ukhetha i-spermidine powder, qwalasela i-bioavailability yemveliso. Jonga ifomyula eyenzelwe ukufunxa ngokufanelekileyo, njengoko oku kuya kuqinisekisa ukuba umzimba wakho unokusebenzisa ngokufanelekileyo i-spermidine ukunikezela ngeenzuzo zayo zempilo.
Ukungafihli kunye novavanyo lomntu wesithathu
Inkqubo yokukhangela kunye nemveliso ye-spermidine powder ehloniphekileyo kufuneka ibonakale. Khangela iibrendi ezibonelela ngolwazi oluneenkcukacha malunga nokufunwa kwezithako zabo kunye nokwenziwa kweemveliso zabo. Ukongeza, uvavanyo lomntu wesithathu ziilabhoratri ezizimeleyo luqinisekisa umgangatho wemveliso kunye nokucoceka. Khangela iimveliso eziye zavavanywa yimibutho yangaphandle ukuqinisekisa ukusebenza kunye nokhuseleko lwazo.
Idosi kunye nobungakanani bokukhonza
Xa uthenga i-spermidine powder, qwalasela idosi kunye nobukhulu bokukhonza obufanele iimfuno zakho. Ezinye iimveliso zinokubonelela ngoxinzelelo oluphezulu lwe-spermidine ngokukhonza, ngelixa ezinye iimveliso zinokubonelela ngedosi esezantsi. Kubalulekile ukumisela idosi efanelekileyo ngokusekelwe kwiinjongo zakho zempilo kwaye udibane nochwepheshe bezempilo xa kuyimfuneko.
Iresiphi kunye nezithako ezongezelelweyo
I-Spermidine powder ifumaneka kwiifom ezahlukeneyo zedosi, kubandakanywa i-capsule, i-powder okanye i-liquid form. Qwalasela ukuba yeyiphi ifomathi efanelene nendlela ophila ngayo kunye nezinto ozikhethayo. Ukongeza, ezinye iimveliso zinokuba nezithako ezongezelelweyo zokuphucula iziphumo ze-spermidine okanye ukuphucula incasa yayo. Nika ingqalelo kuzo naziphi na izithako ezongezelelweyo kwaye uqinisekise ukuba ziyahlangabezana nezinto ozikhethayo zokutya kunye nezithintelo.
Uphononongo lwabathengi kunye nodumo
Ngaphambi kokuthenga, thatha ixesha lokuphanda isidima sohlobo kwaye ufunde uphononongo lwabathengi. Jonga impendulo evela kubantu abasebenzisa imveliso ukufumana ukuqonda malunga nokusebenza kwayo kunye naziphi na iziphumo ebezingalindelekanga. Iimveliso ezinegama elihle kunye nokuphononongwa okuqinisekileyo kwabathengi kunokwenzeka ukuba banikezele ngokuthembekileyo kunye nomgangatho ophezulu we-spermidine powder.
Ixabiso vs ixabiso
Ngelixa ixabiso lingafanele libe kuphela kwesigqibo, kubalulekile ukuqwalasela ixabiso lemveliso ngokunxulumene nexabiso layo. Thelekisa iindleko zomgubo we-spermidine ezahlukeneyo kwaye uqwalasele umgangatho, ubunyulu, kunye neenzuzo ezongezelelweyo zemveliso nganye. Utyalo-mali kwi-powder ye-spermidine ephezulu inokubonelela ngeenzuzo ezinkulu zempilo.
I-Suzhou Myland Pharm's Spermidine Powder-Isondlo esikumgangatho ophezulu
ESuzhou Myland Pharm, sizimisele ukubonelela ngezona mveliso zikumgangatho ophezulu ngamaxabiso angcono. I-powder yethu ye-spermidine ihlolwe ngokungqongqo ukucoceka kunye namandla, ukuqinisekisa ukuba ufumana isongezelelo esiphakamileyo esinokuthembela kuso. Nokuba ufuna ukuxhasa impilo yeselula, ukomeleza amajoni akho omzimba okanye ukuphucula impilo yonke, umgubo wethu we-spermidine lolona khetho lufanelekileyo.
Ineminyaka engama-30 yamava kwaye iqhutywa bubuchwepheshe obuphezulu kunye nezicwangciso ze-R&D eziphuculwe kakhulu, iSuzhou Myland Pharm iphuhlise uluhlu lweemveliso ezikhuphisanayo kwaye ibe sisongezelelo sesayensi yobomi, ukudibanisa isiko kunye nenkampani yeenkonzo zokuvelisa.
Ukongeza, iSuzhou Myland Pharm ikwangumvelisi obhalisiweyo we-FDA. Izixhobo ze-R&D zenkampani, izixhobo zemveliso, kunye nezixhobo zohlalutyo zezanamhlanje kwaye zinemisebenzi emininzi, kwaye zinokuvelisa iikhemikhali ukusuka kwimilligrams ukuya kwiitoni kwisikali, kwaye zithobela imigangatho ye-ISO 9001 kunye neenkcukacha zemveliso ye-GMP.
Umbuzo: Yintoni i-spermidine powder kwaye ihambelana njani nokuguga?
A: I-Spermidine yinto yendalo yepolyamine efumaneka kukutya okuhlukeneyo kunye nomzimba womntu. Uphando lubonisa ukuba i-spermidine inokuba nemiphumo yokuchasana nokuguga ngokukhuthaza impilo yeselula kunye nokuphila ixesha elide.
Umbuzo: I-spermidine powder isebenza njani ukulwa nokuguga?
A: I-Spermidine ikholelwa ukuba isebenze inkqubo yeselula ebizwa ngokuba yi-autophagy, enceda ukususa iiseli ezonakalisiweyo kunye nokukhuthaza ukuvuselelwa kweeseli eziphilileyo. Le nkqubo kucingelwa ukuba idlala indima ephambili ekuthobeni ukuguga.
Umbuzo: Ziziphi iingenelo ezinokuthi zithathe i-spermidine powder yokuguga?
A: Olunye uphando lubonise ukuba ukuxhaswa kwe-spermidine kunokunceda ukuphucula impilo ye-cardiovascular, umsebenzi wengqondo, kunye nokuphila ixesha elide. Isenokuba neenzuzo ezinokubakho kwimpilo yolusu kunye nomsebenzi wokuzikhusela komzimba.
Umbuzo: Ndingaqinisekisa njani umgangatho we-spermidine powder xa uyithenga kwi-intanethi?
A: Khangela umboneleli othembekileyo nosele ethembekile onerekhodi yokubonelela ngezongezo zokutya ezikumgangatho ophezulu. Jonga uphononongo lwabathengi kunye neereyithingi ukujonga ukuthembeka komnikezeli.
Ukuziphendulela: Eli nqaku lelolwazi ngokubanzi kuphela kwaye akufanele lithathwe njengeliphi na icebiso lonyango. Olunye ulwazi lweposti yebhlog luvela kwi-Intanethi kwaye alunamsebenzi. Le webhusayithi inoxanduva kuphela lokuhlela, ukufomatha kunye nokuhlela amanqaku. Injongo yokudlulisa ulwazi olongezelelekileyo ayithethi ukuba uyavumelana neembono zayo okanye uqinisekise ubunyani bomxholo wayo. Soloko udibana nengcali yezempilo ngaphambi kokuba usebenzise naziphi na izongezo okanye wenze utshintsho kwirejimeni yokhathalelo lwempilo.
Ixesha lokuposa: Aug-28-2024