INyaniso malunga nezongezo zeMagnesium: Yintoni ekufuneka uyazi?Nantsi into omawuyazi

Magnesium yiminerali eyimfuneko kunye necofactor kumakhulu eeenzymes.

I-Magnesium ibandakanyeka phantse kuzo zonke iinkqubo eziphambili ze-metabolic kunye ne-biochemical ngaphakathi kweeseli kwaye inoxanduva lwemisebenzi emininzi emzimbeni, kubandakanywa uphuhliso lwamathambo, umsebenzi we-neuromuscular, iindlela zokubonisa, ukugcinwa kwamandla kunye nokudluliselwa, i-glucose, i-lipid kunye ne-protein metabolism, kunye ne-DNA kunye ne-RNA ukuzinza. . kunye nokwanda kweeseli.

I-Magnesium idlala indima ebalulekileyo kwisakhiwo kunye nomsebenzi womzimba womntu. Kukho malunga ne-24-29 grams ye-magnesium kumzimba omdala.

Ngokumalunga ne-50% ukuya kwi-60% ye-magnesium emzimbeni womntu ifumaneka emathanjeni, kwaye i-34% -39% eseleyo ifumaneka kwizicubu ezithambileyo (imisipha kunye nezinye izitho). Umxholo we-magnesium egazini ungaphantsi kwe-1% yomxholo womzimba wonke. I-Magnesium yeyona nto yesibini ininzi i-intracellular cation emva kwe-potassium.

I-Magnesium ithatha inxaxheba kwi-300 ye-metabolic reactions ebalulekileyo emzimbeni, njenge:

Imveliso yamandla

Inkqubo ye-metabolizing carbohydrates kunye namafutha ukuvelisa amandla idinga inani elikhulu leempendulo zeekhemikhali ezixhomekeke kwi-magnesium. I-Magnesium iyadingeka kwi-adenosine triphosphate (ATP) synthesis kwi-mitochondria. I-ATP yimolekyuli enika amandla phantse kuzo zonke iinkqubo zemetabolism kwaye ikhona ngokuyintloko ngohlobo lwe-magnesium kunye ne-magnesium complexes (MgATP).
ukuhlanganiswa kweemolekyuli ezibalulekileyo

IMagnesium iyafuneka kumanyathelo amaninzi ekudityanisweni kwe-deoxyribonucleic acid (DNA), ribonucleic acid (RNA), kunye neeproteni. Iienzyme ezininzi ezibandakanyekayo kwi-carbohydrate kunye ne-lipid synthesis zifuna i-magnesium ukuba isebenze. I-Glutathione yi-antioxidant ebalulekileyo edityaniswe ne-magnesium.

Ukuthuthwa kwe-ion kwiimbumba zeeseli

I-Magnesium yinto efunekayo kuthutho olusebenzayo lwee-ion ezifana ne-potassium kunye ne-calcium kwiimbumba zeeseli. Ngendima yayo kwinkqubo yokuthutha i-ion, i-magnesium ichaphazela ukuqhutyelwa kweempembelelo ze-nerve, ukunyanzeliswa kwemisipha kunye nesigqi sentliziyo esiqhelekileyo.
ukudluliselwa komqondiso weseli

Ukubonakaliswa kweeseli kufuna i-MgATP kwiiprotheni ze-phosphorylate kwaye zenze i-cell signing molecule i-cyclic adenosine monophosphate (cAMP). I-cAMP ibandakanyeka kwiinkqubo ezininzi, kubandakanywa ukukhutshwa kwehomoni ye-parathyroid (PTH) ukusuka kwi-parathyroid glands.

ukufuduka kweeseli

Ukugxilwa kwecalcium kunye nemagnesium kulwelo olujikelezileyo kwiiseli kuphembelela ukufuduka kweentlobo ezininzi zeeseli ezahlukeneyo. Esi siphumo sokufuduka kweeseli singabaluleka ekunyangeni isilonda.

Kutheni abantu banamhlanje benqongophele kwi-magnesium?

Abantu banamhlanje ngokubanzi banengxaki yokungonelanga kwe-magnesium kunye nokunqongophala kwe-magnesium.
Ezona zizathu ziphambili ziquka:

1. Ukulinywa ngokugqithisileyo komhlaba kuye kwakhokelela ekunciphiseni okukhulu kumxholo we-magnesium kumhlaba wangoku, kuchaphazela ngakumbi umxholo we-magnesium kwizityalo kunye nezilwanyana ezidliwayo. Oku kwenza kube nzima kubantu banamhlanje ukufumana i-magnesium eyaneleyo ekutyeni.
2. Izichumisi zekhemikhali ezisetyenziswa ngobuninzi kwizolimo zanamhlanje ikakhulu ziyi-nitrogen, i-phosphorus, kunye nezichumisi ze-potassium, kunye nokuxhaswa kwe-magnesium kunye nezinye izinto ezilandelwayo azihoywa.
3. Izichumisi zemichiza kunye nemvula ye-asidi ibangela i-acidification yomhlaba, ukunciphisa ukufumaneka kwe-magnesium emhlabeni. IMagnesium kwimihlaba eneasidi ihlamba lula kwaye ilahleka ngokulula.
4. Imichiza yokhula equlethe i-glyphosate isetyenziswa kakhulu. Esi sithako sinokubophelela kwi-magnesium, ibangele ukuba i-magnesium emhlabeni ihle ngakumbi kwaye ichaphazele ukufunxwa kwezondlo ezibalulekileyo ezifana ne-magnesium zizityalo.
5. Ukutya kwabantu banamhlanje kunomlinganiselo ophezulu wokutya okucokisekileyo kunye nokucutshungulwayo. Ngexesha lenkqubo yokutya okucokisekileyo kunye nokucutshungulwa, inani elikhulu le-magnesium liya kulahleka.
6. I-asidi ephantsi ye-gastric ithintela ukufunxwa kwe-magnesium. I-asidi yesisu esisezantsi kunye nokungagayeki kunokwenza kube nzima ukugaya ngokupheleleyo ukutya kwaye kwenze iiminerali zibe nzima ukufunxa, okukhokelela ekunqongophelweni kwe-magnesium. Emva kokuba umzimba womntu unqongophele kwi-magnesium, ukukhutshwa kwe-asidi yesisu kuya kuncipha, kuthintele ngakumbi ukufunxa kwe-magnesium. Ukunqongophala kwe-Magnesium kunokwenzeka ukuba kwenzeke ukuba uthatha amayeza anqanda ukukhutshwa kwe-asidi yesisu.
7. Izithako ezithile zokutya zithintela ukufunxwa kwe-magnesium.
Ngokomzekelo, i-tannins kwiti ihlala ibizwa ngokuba yi-tannins okanye i-tannic acid. I-Tannin inamandla e-metal chelating kwaye inokwenza ii-complexes ezinganyibilikiyo kunye neeminerali ezahlukeneyo (ezifana ne-magnesium, isinyithi, i-calcium kunye ne-zinc), echaphazela ukufunxa kwezi minerali. Ukusetyenziswa kwexesha elide lomthamo omkhulu weti enomxholo ophezulu we-tannin, njengeti emnyama kunye neti eluhlaza, kunokukhokelela ekunqongopheni kwe-magnesium. Okona kunamandla kwaye kukrakra ngakumbi iti, kokukhona umxholo we-tannin uphezulu.
I-asidi ye-oxalic kwisipinatshi, i-beet kunye nokunye ukutya kuya kwenza iikhompawundi ezine-magnesium kunye nezinye iiminerali ezinganyibiliki lula emanzini, zenze ezi zinto zikhutshwe emzimbeni kwaye zingakwazi ukufunxwa ngumzimba.
I-Blanching le mifuno inokususa uninzi lwe-oxalic acid. Ukongeza kwisipinatshi kunye neebhiti, ukutya okuphezulu kwi-oxalate kukwaquka: amandongomane kunye nembewu efana ne-almonds, i-cashews, kunye nembewu yesesame; imifuno efana nekale, iokra, iiliki, neepepile; iimbotyi ezifana neembotyi ezibomvu kunye neembotyi ezimnyama; iinkozo ezifana ne-buckwheat kunye nerayisi emdaka; cocoa Ipinki kunye netshokholethi emnyama njl.
I-Phytic acid, efumaneka kakhulu kwimbewu yezityalo, ikwazi ngakumbi ukudibanisa kunye neeminerali ezifana ne-magnesium, i-iron, kunye ne-zinc ukwenza iikhompawundi ezinganyibilikiyo ngamanzi, ezithi ke zikhutshwe emzimbeni. Ukutya ukutya okuninzi okuphezulu kwi-phytic acid kuya kuthintela ukufunxwa kwe-magnesium kwaye kubangele ukulahleka kwe-magnesium.
Ukutya okuphezulu kwi-phytic acid kubandakanya: ingqolowa (ingakumbi ingqolowa), irayisi (ingakumbi irayisi emdaka), i-oats, ibhali kunye nezinye iinkozo; iimbotyi, ii-ertyisi, iimbotyi ezimnyama, iimbotyi zesoya kunye nezinye iimbotyi; iialmonds, imbewu yesesame, imbewu kajongilanga, imbewu yethanga njl. Amandongomane kunye nembewu njl.
8. Iinkqubo zanamhlanje zokunyanga amanzi zisusa amaminerali, kubandakanywa ne-magnesium, emanzini, okubangelwa ukunciphisa i-magnesium intake ngokusebenzisa amanzi okusela.
9. Amanqanaba oxinzelelo olugqithisileyo kubomi banamhlanje aya kukhokelela ekwandeni kokusetyenziswa kwe-magnesium emzimbeni.
10. Ukubila ngokugqithiseleyo ngexesha lokuzilolonga kunokukhokelela ekulahlekeni kwe-magnesium. Izithako ze-diuretic ezifana notywala kunye ne-caffeine ziya kukhawulezisa ukulahlekelwa kwe-magnesium.
Zeziphi iingxaki zempilo ezinokubangelwa kukunqongophala kwemagnesium?

1. I-Acid reflux.
I-Spasm yenzeka ekudibaneni kwe-sphincter ye-esophageal esezantsi kunye nesisu, esinokubangela ukuba i-sphincter ikhululeke, ibangele i-asidi ye-asidi kwaye ibangele i-heartburn. I-Magnesium inokukhulula i-spasms ye-esophageal.

2. Ukungasebenzi kakuhle kwengqondo njenge-Alzheimer's syndrome.
Uphononongo lufumene ukuba amanqanaba e-magnesium kwi-plasma kunye ne-cerebrospinal fluid yezigulane ezine-Alzheimer's syndrome ziphantsi kunabantu abaqhelekileyo. Amanqanaba e-magnesium aphantsi anokunxulumana nokuncipha kwengqondo kunye nobukhulu be-Alzheimer's syndrome.
I-Magnesium ineempembelelo ze-neuroprotective kwaye inokunciphisa uxinzelelo lwe-oxidative kunye neempendulo ezivuthayo kwii-neurons. Omnye wemisebenzi ebalulekileyo ye-magnesium ion kwingqondo kukuthatha inxaxheba kwi-synaptic plasticity kunye ne-neurotransmission, eyona nto ibalulekileyo kwimemori kunye neenkqubo zokufunda. Ukuxhaswa kwe-Magnesium kunokuphucula iplastiki ye-synaptic kunye nokuphucula umsebenzi wokuqonda kunye nememori.
I-Magnesium ineempembelelo ze-antioxidant kunye ne-anti-inflammatory kwaye inokunciphisa uxinzelelo lwe-oxidative kunye nokuvuvukala kwingqondo ye-Alzheimer's syndrome, eyona nto ibalulekileyo kwinkqubo ye-pathological ye-Alzheimer's syndrome.

3. Ukudinwa kwi-Adrenal, ixhala, kunye noloyiko.
Uxinzelelo oluphezulu lwexesha elide kunye noxinzelelo luhlala lukhokelela ekudinweni kwe-adrenal, edla isixa esikhulu se-magnesium emzimbeni. Uxinzelelo lunokubangela ukuba umntu akhuphe i-magnesium kumchamo, ebangela ukusilela kwe-magnesium. I-Magnesium ithomalalisa imithambo-luvo, ikhulula izihlunu, kwaye icothise izinga lokubetha kwentliziyo, inceda ekunciphiseni ukuxhalaba kunye noloyiko.

4. Iingxaki ze-cardiovascular ezifana noxinzelelo lwegazi oluphezulu, i-arrhythmia, i-coronary artery sclerosis / i-calcium deposition, njl.
Ukunqongophala kwe-Magnesium kunokudibaniswa nophuhliso kunye nokunyuka koxinzelelo lwegazi. I-Magnesium inceda ukukhulula imithwalo yegazi kunye nokunciphisa uxinzelelo lwegazi. Ukunqongophala kweMagnesium kubangela ukuba imithambo yegazi ixinzelele, nto leyo enyusa uxinzelelo lwegazi. I-magnesium eyaneleyo inokuphazamisa ibhalansi ye-sodium kunye ne-potassium kwaye yandise umngcipheko wegazi eliphezulu.
Ukunqongophala kwe-Magnesium kuhambelana ngokusondeleyo ne-arrhythmias (njenge-fibrillation ye-atrial, ukubetha kwangaphambi kwexesha). I-Magnesium idlala indima ebalulekileyo ekugcineni umsebenzi wombane wemisipha yentliziyo kunye nesigqi. I-Magnesium yi-stabilizer yomsebenzi wombane weeseli ze-myocardial. Ukunqongophala kwe-Magnesium kukhokelela ekusebenzeni kombane okungaqhelekanga kweeseli ze-myocardial kwaye kwandisa umngcipheko we-arrhythmia. I-Magnesium ibalulekile kulawulo lwesitishi se-calcium, kwaye ukunqongophala kwe-magnesium kunokubangela ukungena kwe-calcium ngokugqithiseleyo kwiiseli zemisipha yenhliziyo kunye nokwandisa umsebenzi ongaqhelekanga wombane.
Amanqanaba aphantsi e-magnesium adibaniswe nokuphuhliswa kwesifo se-coronary artery. I-Magnesium inceda ukuthintela ukuqina kwemithambo kwaye ikhusela impilo yentliziyo. Ukunqongophala kwe-Magnesium kukhuthaza ukubunjwa kunye nokuqhubela phambili kwe-atherosclerosis kwaye kwandisa umngcipheko we-coronary artery stenosis. I-Magnesium inceda ukugcina umsebenzi we-endothelial, kunye nokusilela kwe-magnesium kunokukhokelela endothelial ukungasebenzi kunye nokwandisa umngcipheko we-coronary artery disease.
Ukuqulunqwa kwe-atherosclerosis kuhambelana ngokusondeleyo nempendulo engapheliyo yokuvuvukala. I-Magnesium inezixhobo ezichasayo, ukunciphisa ukuvuvukala kwiindonga ze-artery kunye nokuvimbela ukubunjwa kwe-plaque. Amanqanaba aphantsi e-magnesium adityaniswa neempawu eziphakamileyo ezivuthayo emzimbeni (ezifana neprotheyini ye-C-reactive (CRP)), kwaye ezi mpawu ezivuthayo zihambelana ngokusondeleyo nokwenzeka kunye nokuqhubekela phambili kwe-atherosclerosis.
Uxinzelelo lwe-oxidative yindlela ebalulekileyo ye-pathological ye-atherosclerosis. I-Magnesium ineepropathi ze-antioxidant ezinciphisa ii-radicals zamahhala kunye nokunciphisa umonakalo we-oxidative woxinzelelo kwiindonga ze-arterial. Izifundo zifumene ukuba i-magnesium inokunciphisa i-oxidation ye-low-density lipoprotein (LDL) ngokuthintela uxinzelelo lwe-oxidative, ngaloo ndlela inciphisa umngcipheko we-atherosclerosis.
I-Magnesium ibandakanyeka kwi-lipid metabolism kwaye inceda ukugcina amanqanaba e-lipid enempilo. Ukunqongophala kwe-Magnesium kunokukhokelela kwi-dyslipidemia, kubandakanywa i-cholesterol ephezulu kunye namanqanaba e-triglyceride, awona mngcipheko we-atherosclerosis. Ukuxhaswa kwe-Magnesium kunokunciphisa kakhulu amanqanaba e-triglyceride, ngaloo ndlela kunciphisa umngcipheko we-atherosclerosis.
I-coronary arteriosclerosis ihlala ihamba kunye nokufakwa kwe-calcium kudonga lwe-artery, into ebizwa ngokuba yi-arterial calcification. I-calcification ibangela ukuqina kunye nokunciphisa i-artery, echaphazela ukuhamba kwegazi. I-Magnesium inciphisa ukwenzeka kwe-arterial calcification ngokhuphisana ngokunqanda ukufakwa kwe-calcium kwiiseli ze-vascular smooth muscle.
I-Magnesium inokulawula iziteshi ze-calcium ion kwaye inciphise ukungena ngokugqithiseleyo kwe-calcium ion kwiiseli, ngaloo ndlela ikhusela ukufakwa kwe-calcium. I-Magnesium ikwanceda ekunyibilikiseni i-calcium kwaye ikhokela ekusebenziseni kakuhle komzimba i-calcium, ivumela i-calcium ukuba ibuyele emathanjeni kwaye ikhuthaze impilo yamathambo kunokuba ifakwe kwi-artery. Ukulinganisela phakathi kwe-calcium kunye ne-magnesium kubalulekile ukukhusela idiphozithi ye-calcium kwizicubu ezithambileyo.

5. I-arthritis ebangelwa ukuchithwa kwe-calcium ngokugqithiseleyo.
Iingxaki ezifana ne-calcific tendonitis, i-calcific bursitis, i-pseudogout, kunye ne-osteoarthritis zihambelana nokudumba kunye neentlungu ezibangelwa kukugqithiswa kwe-calcium.
I-Magnesium inokulawula i-calcium metabolism kunye nokunciphisa i-calcium deposition kwi-cartilage kunye nezicubu ze-periarticular. I-Magnesium ineempembelelo ezichasayo kwaye inokunciphisa ukuvuvukala kunye neentlungu ezibangelwa yi-calcium deposition.

6. Umbefu.
Abantu abane-asthma badla ngokuba namanqanaba asezantsi e-magnesium yegazi kunabantu abaqhelekileyo, kwaye amanqanaba aphantsi e-magnesium anxulunyaniswa nobunzima besifuba. Ukuxhaswa kwe-Magnesium kunokunyusa amanqanaba e-magnesium yegazi kubantu abane-asthma, ukuphucula iimpawu ze-asthma kunye nokunciphisa ukuphindaphinda kohlaselo.
I-Magnesium inceda ukukhulula izihlunu ezigudileyo zomoya kwaye inqande i-bronchospasm, ebaluleke kakhulu kubantu abane-asthma. I-Magnesium inefuthe elichasayo, elinokunciphisa impendulo yokuvuvukala kwi-airways, ukunciphisa ukungena kweeseli ezivuthayo kwi-airways kunye nokukhululwa kwabalamli abavuthayo, kunye nokuphucula iimpawu ze-asthma.
I-Magnesium idlala indima ebalulekileyo ekulawuleni amajoni omzimba, ukucinezela iimpendulo ezigqithisileyo zokhuselo lomzimba kunye nokunciphisa ukuchasana nokwaliwa kwesifuba.

7. Izifo zamathumbu.
Ukuqunjelwa: Ukunqongophala kweMagnesium kunokucothisa ukuhamba kwamathumbu kwaye kubangele ukuqunjelwa. I-Magnesium yilaxative yendalo. Ukongezwa kwe-magnesium kunokukhuthaza i-peristalsis yamathumbu kunye nokuthambisa izitulo ngokufunxa amanzi ukunceda ukuzikhulula.
Irritable Bowel Syndrome (IBS): Abantu abane-IBS bahlala benamanqanaba aphantsi e-magnesium. Ukongeza i-magnesium kunokuphelisa iimpawu ze-IBS ezinje ngeentlungu zesisu, ukuqunjelwa, kunye nokuqhina.
Abantu abanesifo sesibindi esivuthayo (IBD), kuquka nesifo sikaCrohn kunye ne-ulcerative colitis, bahlala benamanqanaba aphantsi e-magnesium, mhlawumbi ngenxa ye-malabsorption kunye nesifo sohudo esingapheliyo. Iziphumo ezichasayo ze-Magnesium zinokunceda ukunciphisa impendulo yokuvuvukala kwi-IBD kunye nokuphucula impilo yamathumbu.
Ukukhula kwebhaktheriya emathunjini amancinci (SIBO): Abantu abane-SIBO banokuba ne-magnesium malabsorption kuba ukukhula okugqithisileyo kwebhaktheriya kuchaphazela ukufunxa izondlo. Ukuxhaswa kwe-magnesium efanelekileyo kunokuphucula iimpawu zokuqhaqha kunye neentlungu zesisu ezinxulumene ne-SIBO.

8. Ukucola amazinyo.
Ukugaya amazinyo ngokuqhelekileyo kwenzeka ebusuku kwaye kunokwenzeka ngenxa yezizathu ezahlukeneyo. Oku kuquka uxinezeleko, ukuxhalaba, ukungalali kakuhle, ukulunywa kakubi, nemiphumo engathandekiyo yamayeza athile. Kwiminyaka yakutshanje, uphando lubonise ukuba ukunqongophala kwe-magnesium kunokunxulumana nokusila kwamazinyo, kwaye ukongezwa kwe-magnesium kunokuba luncedo ekunciphiseni iimpawu zokusila kwamazinyo.
I-Magnesium idlala indima ephambili ekuqhutyweni kwemithambo-luvo kunye nokuphumla kwemisipha. Ukunqongophala kwe-Magnesium kunokubangela ukuxinezeleka kwemisipha kunye ne-spasms, kwandisa umngcipheko wokugedla kwamazinyo. I-Magnesium ilawula inkqubo ye-nervous kwaye inokunceda ukunciphisa uxinzelelo kunye nokuxhalaba, nto leyo edla ngokubangela ukugedla kwamazinyo.
Ukongezwa kweMagnesium kunokunceda ukunciphisa uxinzelelo kunye namanqanaba okuxhalaba, nto leyo enokunciphisa ukugedla kwamazinyo okubangelwa zezi zinto zengqondo. I-Magnesium inceda izihlunu ukuba ziphumle kwaye inciphise ukugogeka kwezihlunu ebusuku, nto leyo enokunciphisa ukubakho kwamazinyo. I-Magnesium inokukhuthaza ukuphumla kunye nokuphucula umgangatho wokulala ngokulawula umsebenzi wee-neurotransmitters ezifana ne-GABA.

9. Amatye ezintso.
Uninzi lweentlobo zamatye ezintso yi-calcium phosphate kunye namatye e-calcium oxalate. Ezi zinto zilandelayo zibangela amatye kwizintso:
① Ukonyuka kwe-calcium kumchamo. Ukuba ukutya kuqulethe isixa esikhulu seswekile, i-fructose, utywala, ikofu, njl., oku kutya okune-acidic kuya kutsala i-calcium emathanjeni ukuze kunciphise i-asidi kunye ne-metabolize ngokusebenzisa izintso. Ukutya okuninzi kwe-calcium okanye ukusetyenziswa kwe-calcium eyongezelelweyo kuya kwandisa umthamo we-calcium kumchamo.
②I-oxalic acid kumchamo iphezulu kakhulu. Ukuba utya kakhulu ukutya okune-oxalic acid-rich, i-oxalic acid kolu kutya iya kudibanisa ne-calcium ukwenza i-insoluble calcium oxalate, enokukhokelela kumatye ezintso.
③Ukuphelelwa ngamanzi emzimbeni. Ibangela ukwanda kwe-calcium kunye nezinye iiminerali kumchamo.
④Ukutya okuphezulu kwe-phosphorus. Ukutya okuninzi okuqukethe i-phosphorus (ezifana neziphuzo ze-carbonated), okanye i-hyperparathyroidism, iya kwandisa amanqanaba e-phosphoric acid emzimbeni. I-asidi ye-Phosphoric iya kutsala i-calcium emathanjeni kwaye ivumele i-calcium ukuba ifakwe kwizintso, yenze amatye e-calcium phosphate.
I-Magnesium inokudibanisa ne-oxalic acid ukwenza i-magnesium oxalate, ene-solubility ephezulu kune-calcium oxalate, enokunciphisa ngokufanelekileyo imvula kunye ne-crystallization ye-calcium oxalate kunye nokunciphisa umngcipheko wamatye ezintso.
I-Magnesium inceda ukunyibilika kwe-calcium, igcina i-calcium inyibilika egazini kwaye ikhusela ukwakheka kweekristale eziqinileyo. Ukuba umzimba awunayo i-magnesium eyaneleyo kwaye une-calcium engaphezulu, iindlela ezahlukeneyo zokubala zinokuthi zenzeke, kubandakanywa amatye, i-muscle spasms, ukuvutha kwe-fibrous, i-arterial calcification (i-atherosclerosis), ukubalwa kwezicubu zesifuba, njl.

10.Parkinson.
Isifo sikaParkinson sibangelwa ikakhulu kukulahleka kwe-dopaminergic neurons engqondweni, okukhokelela ekunciphiseni amanqanaba e-dopamine. Ibangela ukulawulwa kokuhamba okungaqhelekanga, okubangelwa ukungcangcazela, ukuqina, i-bradykinesia, kunye nokungazinzi kwe-postural.
Ukunqongophala kweMagnesium kunokukhokelela kukungasebenzi kakuhle kwe-neuronal kunye nokufa, okonyusa umngcipheko wezifo ze-neurodeergenerative, kubandakanya nesifo sikaParkinson. I-Magnesium ineempembelelo ze-neuroprotective, inokuzinzisa i-membrane ye-nerve cell, ilawula i-calcium ion channels, kunye nokunciphisa i-neuron excitability kunye nomonakalo weseli.
I-Magnesium yi-cofactor ebalulekileyo kwinkqubo ye-enzyme ye-antioxidant, inceda ukunciphisa uxinzelelo lwe-oxidative kunye neempendulo ezivuthayo. Abantu abanesifo sikaParkinson bahlala benamanqanaba aphezulu oxinzelelo lwe-oxidative kunye nokudumba, okukhawulezisa umonakalo we-neuronal.
Uphawu oluphambili lwesifo sikaParkinson kukulahlekelwa yi-dopaminergic neurons kwi-substantia nigra. I-Magnesium inokukhusela ezi neurons ngokunciphisa i-neurotoxicity kunye nokukhuthaza ukusinda kwe-neuronal.
I-Magnesium inceda ukugcina umsebenzi oqhelekileyo we-nerve conduction kunye ne-muscle contraction, kwaye ikhulula iimpawu zemoto ezifana nokungcangcazela, ukuqina kunye ne-bradykinesia kwizigulane ezine-Parkinson's disease.

11. Ukudakumba, ukuxhalaba, ukucaphuka kunye nezinye izifo zengqondo.
I-Magnesium ngumlawuli obalulekileyo wee-neurotransmitters ezininzi (umzekelo, i-serotonin, i-GABA) edlala indima ebalulekileyo ekulawuleni isimo sengqondo kunye nokulawula ukuxhalaba. Uphando lubonisa ukuba i-magnesium inokunyusa amanqanaba e-serotonin, i-neurotransmitter ebalulekileyo ehambelana nokulinganisela kweemvakalelo kunye neemvakalelo zokuphila kakuhle.
I-Magnesium inokuthintela ukusetyenziswa ngokugqithiseleyo kwe-NMDA receptors. I-Hyperactivation ye-NMDA receptors inxulunyaniswa nokunyuka kwe-neurotoxicity kunye neempawu zokudakumba.
I-Magnesium ine-anti-inflammatory kunye ne-antioxidant properties ezinokunciphisa ukuvuvukala kunye noxinzelelo lwe-oxidative emzimbeni, zombini ezi zidibaniswe nokudakumba kunye nokuxhalaba.
I-axis ye-HPA idlala indima ebalulekileyo ekuphenduleni uxinzelelo kunye nokulawulwa kweemvakalelo. I-Magnesium inokuphelisa uxinzelelo kunye noxinzelelo ngokulawula i-axis ye-HPA kunye nokunciphisa ukukhutshwa kweehomoni zoxinzelelo ezifana ne-cortisol.

12. Ukudinwa.
Ukunqongophala kwe-Magnesium kunokukhokelela ekudinweni kunye neengxaki ze-metabolic, ngokuyinhloko kuba i-magnesium idlala indima ebalulekileyo kwimveliso yamandla kunye neenkqubo ze-metabolic. I-Magnesium inceda umzimba ugcine amanqanaba aqhelekileyo amandla kunye nemisebenzi ye-metabolic ngokuzinzisa i-ATP, isebenze ii-enzymes ezahlukeneyo, ukunciphisa uxinzelelo lwe-oxidative, kunye nokugcina i-nerve kunye nemisipha yokusebenza. Ukongezwa kwe-magnesium kunokuphucula ezi mpawu kunye nokuphucula amandla kunye nempilo jikelele.
I-Magnesium yi-cofactor yee-enzymes ezininzi, ngakumbi kwiinkqubo zokuvelisa amandla. Idlala indima ephambili kwimveliso ye-adenosine triphosphate (ATP). I-ATP yeyona nto ithwala amandla kwiiseli, kwaye i-ion ye-magnesium ibalulekile kuzinzo kunye nomsebenzi we-ATP.
Ekubeni i-magnesium ibalulekile kwimveliso ye-ATP, ukungabikho kwe-magnesium kunokukhokelela ekuveliseni i-ATP eyaneleyo, okubangelwa ukunciphisa amandla okunikezelwa kweeseli, okubonakala njengokukhathala ngokubanzi.
I-Magnesium ithatha inxaxheba kwiinkqubo ze-metabolic ezifana ne-glycolysis, umjikelezo we-tricarboxylic acid (umjikelezo we-TCA), kunye ne-phosphorylation ye-oxidative. Ezi nkqubo zezona ndlela ziphambili zeeseli zokwenza i-ATP. I-molecule ye-ATP kufuneka idibaniswe kunye ne-magnesium ion ukugcina ifom esebenzayo (Mg-ATP). Ngaphandle kwe-magnesium, i-ATP ayikwazi ukusebenza ngokufanelekileyo.
I-Magnesium isebenza njenge-cofactor yee-enzymes ezininzi, ngakumbi ezo zibandakanyeka kwi-metabolism yamandla, njenge-hexokinase, i-pyruvate kinase, kunye ne-adenosine triphosphate synthetase. Ukunqongophala kwe-Magnesium kubangela ukuncipha komsebenzi wezi enzyme, ezichaphazela ukuveliswa kwamandla kunye nokusetyenziswa kweseli.
I-Magnesium ineempembelelo ze-antioxidant kwaye inokunciphisa uxinzelelo lwe-oxidative emzimbeni. Ukunqongophala kweMagnesium kwandisa amanqanaba oxinzelelo lwe-oxidative, okukhokelela kumonakalo weseli kunye nokudinwa.
I-Magnesium nayo ibalulekile ekuqhubeni imithambo-luvo kunye nokuncipha kwemisipha. Ukunqongophala kwe-Magnesium kunokukhokelela kukungasebenzi kakuhle kwemithambo-luvo kunye nezihlunu, okuyandisa ngakumbi ukudinwa.

13. Isifo sikashukela, ukunganyangeki kwe-insulin kunye nezinye izifo ze-metabolic syndromes.
I-Magnesium iyinxalenye ebalulekileyo yokubonakaliswa kwe-insulin receptor kwaye ibandakanyeka kwimfihlo kunye nesenzo se-insulin. Ukunqongophala kwe-Magnesium kunokukhokelela ekunciphiseni i-insulin receptor sensitivity kunye nokwandisa umngcipheko wokunganyangeki kwe-insulin. Ukunqongophala kwe-Magnesium kuhambelana nokunyuka kweziganeko zokuxhatshazwa kwe-insulin kunye nohlobo lwe-2 yeswekile.
I-Magnesium ibandakanyeka ekusebenzeni kwee-enzyme ezahlukeneyo ezidlala indima ebalulekileyo kwi-glucose metabolism. Ukunqongophala kwe-Magnesium kuchaphazela i-glycolysis kunye nokusetyenziswa kwe-glucose ephakathi kwe-insulin. Uphononongo lufumene ukuba ukusilela kwe-magnesium kunokubangela ukuphazamiseka kwe-glucose metabolism, ukwandisa amanqanaba eswekile yegazi kunye ne-glycated hemoglobin (HbA1c).
I-Magnesium ineempembelelo ze-antioxidant kunye ne-anti-inflammatory kwaye inokunciphisa uxinzelelo lwe-oxidative kunye neempendulo ezivuthayo emzimbeni, eziziindlela ezibalulekileyo ze-pathological zesifo sikashukela kunye nokuxhatshazwa kwe-insulin. Ubume be-magnesium ephantsi bonyusa iimpawu zoxinzelelo lwe-oxidative kunye nokudumba, ngaloo ndlela kukhuthaza uphuhliso lokunganyangeki kwe-insulin kunye nesifo seswekile.
Ukuxhaswa kwe-Magnesium kwandisa i-insulin receptor sensitivity kunye nokuphucula i-insulin-mediated glucose uptake. Ukuxhaswa kwe-Magnesium kunokuphucula imetabolism ye-glucose kunye nokunciphisa i-glucose yegazi ngokukhawuleza kunye namanqanaba e-glycated hemoglobin ngeendlela ezininzi. I-Magnesium inokunciphisa umngcipheko we-metabolic syndrome ngokuphucula ukuvakalelwa kwe-insulin, ukunciphisa uxinzelelo lwegazi, ukunciphisa i-lipid abnormalities, kunye nokunciphisa ukuvutha.

14. Intloko kunye nemigraines.
I-Magnesium idlala indima ephambili ekukhululweni kwe-neurotransmitter kunye nokulawulwa komsebenzi we-vascular. Ukunqongophala kweMagnesium kunokukhokelela kukungalingani kwe-neurotransmitter kunye ne-vasospasm, enokubangela intloko ebuhlungu kunye nemigraines.
Amanqanaba aphantsi e-magnesium adibaniswa nokunyuka kokuvuvukala kunye noxinzelelo lwe-oxidative, olunokubangela okanye lube mbi ngakumbi imigraines. I-Magnesium ineempembelelo ezichasayo kunye ne-antioxidant, ukunciphisa ukuvuvukala kunye noxinzelelo lwe-oxidative.
I-Magnesium inceda ukukhulula imithambo yegazi, ukunciphisa i-vasospasm, kunye nokuphucula ukuhamba kwegazi, ngaloo ndlela kukhulula i-migraines.

15. Iingxaki zokulala ezifana nokungalali, ukungalali kakuhle, ukuphazamiseka kwesigqi se-circadian, kunye nokuvuka lula.
Iziphumo zolawulo lwe-Magnesium kwinkqubo ye-nervous zinceda ukukhuthaza ukuphumla kunye nokuzola, kwaye ukongezwa kwe-magnesium kunokuphucula kakhulu ubunzima bokulala kwizigulana eziphuthelwa kwaye kuncede ukwandisa ixesha lokulala lilonke.
I-Magnesium ikhuthaza ubuthongo obunzulu kwaye iphucula umgangatho wokulala ngokubanzi ngokulawula umsebenzi wee-neurotransmitters ezifana ne-GABA.
I-Magnesium idlala indima ebalulekileyo ekulawuleni iwotshi yebhayoloji yomzimba. I-Magnesium inokunceda ukubuyisela isigqi esiqhelekileyo se-circadian ngokuchaphazela ukukhutshwa kwe-melatonin.
Umphumo wokuthomalalisa we-magnesium unokunciphisa inani lokuvuka ebusuku kwaye ukhuthaze ubuthongo obuqhubekayo.

16. Ukudumba.
I-calcium eyongeziweyo inokukhokelela ngokulula ekudumbeni, ngelixa i-magnesium inokuthintela ukuvuvukala.
I-Magnesium yinto ebalulekileyo kumsebenzi oqhelekileyo we-immune system. Ukunqongophala kwe-Magnesium kunokukhokelela ekusebenzeni okungaqhelekanga kweeseli zomzimba kunye nokwandisa iimpendulo ezivuthayo.
Ukunqongophala kwe-Magnesium kukhokelela kumanqanaba aphakamileyo oxinzelelo lwe-oxidative kwaye kwandisa ukuveliswa kweeradicals zamahhala emzimbeni, ezinokuthi ziqalise kwaye zandise ukuvuvukala. Njenge-antioxidant yendalo, i-magnesium inokunciphisa i-radicals yamahhala emzimbeni kwaye inciphise uxinzelelo lwe-oxidative kunye nokuphendula okuvuthayo. Ukuxhaswa kwe-Magnesium kunokunciphisa kakhulu amanqanaba oxinzelelo lwe-oxidative kunye nokunciphisa ukuvuvukala okunxulumene noxinzelelo lwe-oxidative.
I-Magnesium yenza i-anti-inflammatory effects ngokusebenzisa iindlela ezininzi, kubandakanywa nokuvimbela ukukhululwa kwe-cytokines e-pro-inflammatory kunye nokunciphisa ukuveliswa kwabalamli abavuthayo. I-Magnesium inokuthintela amanqanaba ezinto eziphazamisayo ezifana ne-tumor necrosis factor-α (TNF-α), i-interleukin-6 (IL-6), kunye ne-C-reactive protein (CRP).

17. I-Osteoporosis.
Ukunqongophala kwe-Magnesium kunokukhokelela ekunciphiseni ukuxinana kwamathambo kunye namandla amathambo. I-Magnesium iyinxalenye ebalulekileyo kwinkqubo ye-bone mineralization kwaye ibandakanyeka ngokuthe ngqo ekubunjweni kwe-matrix yamathambo. I-magnesium enganelanga inokukhokelela ekunciphiseni umgangatho we-matrix yamathambo, okwenza amathambo achaphazeleke ngakumbi kumonakalo.
Ukunqongophala kwe-Magnesium kunokukhokelela ekugqithiseni kwe-calcium emathanjeni, kwaye i-magnesium idlala indima ebalulekileyo ekulawuleni ibhalansi ye-calcium emzimbeni. I-Magnesium ikhuthaza ukufunxa kunye nokusetyenziswa kwe-calcium ngokuvula i-vitamin D, kwaye ilawula i-calcium metabolism ngokuchaphazela ukukhutshwa kwehomoni ye-parathyroid (PTH). Ukunqongophala kwe-Magnesium kunokukhokelela ekusebenzeni okungaqhelekanga kwe-PTH kunye ne-vitamin D, ngaloo ndlela kubangele ukuphazamiseka kwe-calcium metabolism kunye nokwandisa umngcipheko we-calcium leaching emathanjeni.
I-Magnesium inceda ukukhusela i-calcium kwizicubu ezithambileyo kwaye igcine ukugcinwa okufanelekileyo kwe-calcium emathanjeni. Xa i-magnesium inqongophele, i-calcium ilahleka ngokulula emathanjeni kwaye ifakwe kwizicubu ezithambileyo.

20. Ukuxhatshazwa kwemisipha kunye ne-cramps, ubuthathaka bemisipha, ukukhathala, ukungcangcazela okungaqhelekanga kwemisipha (i-eyelid twitching, ulwimi olulumayo, njl.), intlungu engapheliyo yemisipha kunye nezinye iingxaki zemisipha.
I-Magnesium idlala indima ephambili kwi-nerve conduction kunye nokucutshulwa kwemisipha. Ukunqongophala kwe-Magnesium kunokubangela ukuhanjiswa kwemithambo-luvo engaqhelekanga kunye nokwanda kokonwaba kweeseli zezihlunu, okukhokelela kwi-spasms nezihlunu. Ukongezwa kwe-magnesium kunokubuyisela i-nerve conduction eqhelekileyo kunye nokusebenza kwe-muscle contraction kunye nokunciphisa ukugqithisa okugqithisileyo kweeseli zemisipha, ngaloo ndlela kuncitshiswe i-spasms kunye ne-cramps.
I-Magnesium ibandakanyeka kwi-metabolism yamandla kunye nokuveliswa kwe-ATP (umthombo wamandla oyintloko weseli). Ukunqongophala kwe-Magnesium kunokukhokelela ekunciphiseni ukuveliswa kwe-ATP, okuchaphazela ukuchithwa kwemisipha kunye nomsebenzi, okukhokelela kubuthathaka bemisipha kunye nokukhathala. Ukunqongophala kweMagnesium kunokukhokelela ekonyukeni kokudinwa kunye nokuncipha komthamo wokuzilolonga emva komthambo. Ngokuthatha inxaxheba ekuveliseni i-ATP, i-magnesium inika amandla okwaneleyo, iphucula umsebenzi we-muscle contraction, iphucula amandla emisipha, kwaye iyanciphisa ukukhathala. Ukongezwa kwe-magnesium kunokuphucula ukunyamezela komthambo kunye nokusebenza kwezihlunu kunye nokunciphisa ukukhathala emva kokuzivocavoca.
Impembelelo yokulawula i-Magnesium kwinkqubo ye-nervous inokuchaphazela ukunyanzeliswa kwemisipha yokuzithandela. Ukunqongophala kweMagnesium kunokubangela ukungasebenzi kakuhle kwemithambo-luvo, kubangele ukungcangcazela kwemisipha kunye nesifo semilenze engaphumliyo (RLS). Iziphumo zokuthomalalisa ze-magnesium zinokunciphisa inkqubo ye-nervous over-excitability, ukunciphisa iimpawu ze-RLS, kunye nokuphucula umgangatho wokulala.
I-Magnesium ine-anti-inflammatory kunye ne-antioxidant properties, ukunciphisa ukuvuvukala kunye noxinzelelo lwe-oxidative emzimbeni. Ezi zinto zidibene neentlungu ezingapheliyo. I-Magnesium ibandakanyeka kulawulo lwee-neurotransmitters ezininzi, ezifana ne-glutamate kunye ne-GABA, edlala indima ephambili ekuboneni intlungu. Ukunqongophala kwe-Magnesium kunokukhokelela kulawulo lweentlungu ezingaqhelekanga kunye nokwanda kokuqonda intlungu. Ukuxhaswa kwe-Magnesium kunokunciphisa iimpawu zentlungu engapheliyo ngokulawula amanqanaba e-neurotransmitter.

21.Ukulimala kwezemidlalo kunye nokubuyisela.
I-Magnesium idlala indima ebalulekileyo ekuqhutyweni kwe-nerve kunye nokunciphisa imisipha. Ukunqongophala kwe-Magnesium kunokubangela ukugqithiswa kwemisipha kunye nokunyanzeliswa okungafunekiyo, kwandisa umngcipheko we-spasms kunye ne-cramps. Ukongezwa kwe-magnesium kunokulawula ukusebenza kwe-nerve kunye ne-muscle kunye nokunciphisa i-spasms ye-muscle kunye ne-cramps emva kokuzivocavoca.
I-Magnesium yinxalenye ephambili ye-ATP (umthombo wamandla oyintloko weseli) kwaye ibandakanyeka kwimveliso yamandla kunye ne-metabolism. Ukunqongophala kwe-Magnesium kunokukhokelela ekuveliseni amandla aneleyo, ukunyuka kokukhathala, kunye nokunciphisa ukusebenza kwezemidlalo. Ukuxhaswa kwe-Magnesium kunokuphucula ukunyamezela komzimba kunye nokunciphisa ukukhathala emva kokuzivocavoca.
I-Magnesium inezixhobo ezichasayo ezinokunciphisa impendulo yokuvuvukala okubangelwa ngumsebenzi kunye nokukhawuleza ukubuyiswa kwemisipha kunye nezicubu.
I-lactic acid yi-metabolite eveliswa ngexesha le-glycolysis kwaye iveliswa ngamanani amakhulu ngexesha lokuzilolonga ngamandla. I-Magnesium i-cofactor yee-enzymes ezininzi ezinxulumene ne-metabolism yamandla (efana ne-hexokinase, i-pyruvate kinase), edlala indima ebalulekileyo kwi-glycolysis kunye ne-lactate metabolism. I-Magnesium inceda ukukhawulezisa ukucocwa kunye nokuguqulwa kwe-lactic acid kunye nokunciphisa i-lactic acid accumulation.

 

Ungajonga njani ukuba uyasilela kwi-magnesium?

Ukunyaniseka, ukuzama ukufumanisa elona nqanaba le-magnesium emzimbeni wakho ngezinto zovavanyo ngokubanzi kuyingxaki enzima kakhulu.

Kukho malunga ne-24-29 grams ye-magnesium emzimbeni wethu, phantse i-2/3 yayo emathanjeni kunye ne-1/3 kwiiseli ezahlukeneyo kunye nezicubu. I-magnesium egazini kuphela i-akhawunti malunga ne-1% yomxholo we-magnesium womzimba wonke (kuquka i-serum 0.3% kwi-erythrocytes kunye ne-0.5% kwiiseli ezibomvu zegazi).
Okwangoku, kwizibhedlele ezininzi eTshayina, uvavanyo lwesiqhelo lomxholo we-magnesium luhlala "luvavanyo lwe-serum magnesium". Uluhlu oluqhelekileyo lolu vavanyo luphakathi kwe-0.75 kunye ne-0.95 mmol / L.

Nangona kunjalo, ngenxa yokuba i-magnesium ye-serum ibala kuphela ngaphantsi kwe-1% yomxholo we-magnesium womzimba uwonke, ayinakho ngokwenene kwaye ibonise ngokuchanekileyo umxholo we-magnesium kwizicubu ezahlukeneyo kunye neeseli zomzimba.

Umxholo we-magnesium kwi-serum ubaluleke kakhulu kumzimba kwaye yinto ephambili yokuqala. Ngenxa yokuba i-magnesium ye-serum kufuneka igcinwe ekugxininiseni okusebenzayo ukugcina imisebenzi ethile ebalulekileyo, njengokubetha kwentliziyo.

Ke xa ukutya kwakho kwe-magnesium kuqhubeka nokunqongophala, okanye umzimba wakho ujongene nesifo okanye uxinzelelo, umzimba wakho uya kuqala ukukhupha i-magnesium kwizicubu okanye iiseli ezinjengezihlunu kwaye uyihambise egazini ukunceda ukugcina amanqanaba aqhelekileyo e-serum magnesium.

Ke ngoko, xa ixabiso lakho le-magnesium ye-serum libonakala likuluhlu oluqhelekileyo, i-magnesium inokuphela kwezinye izihlunu kunye neeseli zomzimba.

Kwaye xa uvavanya kwaye ufumanisa ukuba i-serum magnesium iphantsi, umzekelo, ngaphantsi koluhlu oluqhelekileyo, okanye kufuphi nomda ophantsi woluhlu oluqhelekileyo, kuthetha ukuba umzimba sele ukwimeko yokusilela okukhulu kwe-magnesium.

Iiseli zegazi ezibomvu (RBC) inqanaba le-magnesium kunye novavanyo lwenqanaba leplatelet magnesium zichaneke ngakumbi kunovavanyo lwe-serum magnesium. Kodwa ayikamelanga ngokwenyani amanqanaba okwenyani e-magnesium yomzimba.

Ngenxa yokuba iiseli ezibomvu zegazi okanye iiplatelet zine-nuclei kunye ne-mitochondria, i-mitochondria iyona nto ibaluleke kakhulu yokugcina i-magnesium. Iiplatelets zibonisa ngokuchanekileyo utshintsho lwamva nje kumanqanaba e-magnesium kuneeseli ezibomvu zegazi kuba iiplatelet zihlala kuphela iintsuku eziyi-8-9 xa kuthelekiswa neeseli ezibomvu zegazi '100-120 iintsuku.

Iimvavanyo ezichanekileyo zezi: i-muscle cell biopsy magnesium content, sublingual epithelial cell content magnesium.
Nangona kunjalo, ukongeza kwi-serum magnesium, izibhedlele zasekhaya okwangoku zinokwenza kancinci kwezinye iimvavanyo ze-magnesium.
Kungenxa yoko le nto inkqubo yezonyango yendabuko kudala ingakuhoyi ukubaluleka kwe-magnesium, kuba ukugweba nje ukuba isigulana sinqongophele kwi-magnesium ngokulinganisa amaxabiso e-serum magnesium kaninzi kukhokelela ekugwebeni kakubi.
Ukugweba inqanaba le-magnesium yesigulana kuphela ngokulinganisa i-serum magnesium yingxaki enkulu kuxilongo lwezonyango lwangoku kunye nonyango.

Unokukhetha njani isongezelelo esifanelekileyo se-magnesium?

Zingaphezulu kweshumi elinesibini iindidi ezahlukeneyo zezongezo zemagnesium kwimarike, ezinje ngemagnesium oxide, magnesium sulfate, magnesium chloride, magnesium citrate, magnesium glycinate, magnesium threonate, magnesium taurate, njl.
Nangona iintlobo ezahlukeneyo zezongezelelo ze-magnesium zinokuphucula ingxaki yokunqongophala kwe-magnesium, ngenxa yokungafani kwesakhiwo se-molecular, amazinga okufunxa ayahluka kakhulu, kwaye aneempawu zawo kunye nokusebenza kakuhle.
Ke ngoko, kubaluleke kakhulu ukukhetha isongezelelo se-magnesium esikufanelayo kwaye sisombulule iingxaki ezithile.

Unokufunda ngononophelo lo mxholo ulandelayo, kwaye emva koko ukhethe uhlobo lwe-magnesium eyongezelelweyo olufanelekileyo kuwe ngokusekelwe kwiimfuno zakho kunye neengxaki ofuna ukugxila ekuzisombululeni.

I-Magnesium supplements ayikhuthazwa

i-magnesium oxide

Inzuzo ye-magnesium oxide kukuba inomxholo ophezulu we-magnesium, oko kukuthi, igram nganye ye-magnesium oxide inokubonelela ngee-ion ze-magnesium ngaphezu kwezinye izongezo ze-magnesium ngexabiso eliphantsi.

Nangona kunjalo, oku kukuncedisa kwe-magnesium enezinga eliphantsi kakhulu lokufunxa, kuphela malunga ne-4%, oku kuthetha ukuba uninzi lwe-magnesium alukwazi ukufunxa ngokwenene kwaye lusetyenziswe.

Ukongezelela, i-magnesium oxide inempembelelo ebalulekileyo ye-laxative kwaye ingasetyenziselwa ukunyanga ukuqunjelwa.

Ithambisa ilindle ngokufunxa amanzi emathunjini, ikhuthaza ukumila kwamathumbu emathumbu, kwaye inceda ekukhunjweni. Amanani aphezulu e-magnesium oxide anokubangela ukuphazamiseka kwesisu, kubandakanya urhudo, iintlungu zesisu, kunye neentlungu zesisu. Abantu abanobuthathaka besisu kufuneka basebenzise ngononophelo.

I-Magnesium sulfate

Izinga lokufunxa kwe-magnesium sulfate nalo liphantsi kakhulu, ngoko ke uninzi lwe-magnesium sulfate ethatyathwe ngomlomo ayinakufunxwa kwaye iya kukhutshelwa ilindle endaweni yokuba ifakwe egazini.

I-Magnesium sulfate nayo inefuthe elibonakalayo le-laxative, kwaye umphumo wayo we-laxative udla ngokubonakala kwimizuzu engama-30 ukuya kwiiyure ezi-6. Oku kungenxa yokuba i-ion ye-magnesium engaxutywanga ifunxa amanzi emathunjini, inyuse umthamo wamathumbu emathunjini, kwaye ikhuthaze ukuhlanjululwa.
Nangona kunjalo, ngenxa yokunyibilika kwayo okuphezulu emanzini, i-magnesium sulfate ihlala isetyenziselwa inaliti ye-intravenous kwiimeko ezingxamisekileyo esibhedlele ukunyanga i-hypomagnesemia ebukhali, i-eclampsia, uhlaselo olubukhali lwe-asthma, njl.

Kungenjalo, i-magnesium sulfate ingasetyenziswa njengeetyuwa zokuhlambela (ekwaziwa ngokuba ziityuwa ze-Epsom), ezifunxwa ngolusu ukuze zithomalalise iintlungu zezihlunu kunye nokudumba nokukhuthaza ukuphumla nokuchacha.

i-magnesium aspartate

I-Magnesium aspartate luhlobo lwe-magnesium eyenziwe ngokudibanisa i-aspartic acid kunye ne-magnesium, eyongezelelekileyo ye-magnesium ephikisanayo.
Inzuzo yile: I-Magnesium aspartate ine-bioavailability ephezulu, oku kuthetha ukuba inokufunxwa ngokufanelekileyo kwaye isetyenziswe ngumzimba ukunyusa ngokukhawuleza amanqanaba e-magnesium egazini.
Ngaphezu koko, i-aspartic acid yi-amino acid ebalulekileyo ebandakanyekayo kwi-metabolism yamandla. Idlala indima ephambili kumjikelezo we-tricarboxylic acid (umjikelezo we-Krebs) kwaye inceda iiseli zivelise amandla (ATP). Ke ngoko, i-magnesium aspartate inokunceda ukwandisa amanqanaba amandla kunye nokunciphisa iimvakalelo zokudinwa.
Nangona kunjalo, i-aspartic acid yi-amino acid evuselelayo, kwaye ukugqithisa ngokugqithiseleyo kunokubangela ukugqithiswa kwenkqubo ye-nervous, kubangele ukuxhalaba, ukuphuthelwa, okanye ezinye iimpawu ze-neurological.
Ngenxa ye-excitability ye-aspartate, abantu abathile abanovelwano kwi-amino acids ye-excitatory (ezifana nezigulane ezinezifo ezithile ze-neurological) abanako ukufaneleka kwixesha elide okanye eliphezulu lolawulo lwe-magnesium aspartate.

Izincedisi zeMagnesium ezicetyiswayo

I-Magnesium L-Threonate

I-Magnesium threonate yenziwe ngokudibanisa i-magnesium kunye ne-L-threonate. I-Magnesium threonate ineenzuzo ezibalulekileyo ekuphuculeni ukusebenza kwengqondo, ukuthomalalisa ixhala kunye nokudakumba, ukunceda ukulala, kunye ne-neuroprotection ngenxa yeepropathi zayo zeekhemikhali ezikhethekileyo kunye nokungena okusebenzayo kwesithintelo segazi-ingqondo.

Ingena kwisithintelo seGazi-Brain: I-Magnesium threonate ibonakaliswe isebenza ngakumbi ekungeneni kumqobo wegazi-ingqondo, inika inzuzo ekhethekileyo ekwandiseni amanqanaba e-magnesium yengqondo. Uphononongo lubonise ukuba i-magnesium threonate inokunyusa kakhulu ukugxila kwe-magnesium kwi-cerebrospinal fluid, ngaloo ndlela iphucula umsebenzi wokuqonda.

Ukuphucula umsebenzi wokuqonda kunye nenkumbulo: Ngenxa yokukwazi ukunyusa amanqanaba e-magnesium kwingqondo, i-magnesium threonate inokuphucula kakhulu umsebenzi wokuqonda kunye nememori, ngakumbi kubantu abadala kunye nabo banokukhubazeka kwengqondo. Uphando lubonisa ukuba i-magnesium threonate supplementation inokuphucula kakhulu amandla okufunda kwengqondo kunye nokusebenza kwenkumbulo yexesha elifutshane.

Ukunciphisa ukuxhalaba kunye noxinzelelo: I-Magnesium idlala indima ebalulekileyo kwi-nerve conduction kunye ne-neurotransmitter balance. I-Magnesium threonate inokunceda ukunciphisa iimpawu zokuxhalaba kunye nokudakumba ngokunyusa ngokufanelekileyo amanqanaba e-magnesium engqondweni.
I-Neuroprotection: Abantu abasengozini yezifo ze-neurodeergenerative, ezifana ne-Alzheimer kunye nesifo sika-Parkinson. I-Magnesium threonate ineziphumo ze-neuroprotective kwaye inceda ukuthintela kunye nokucothisa ukuqhubeka kwezifo ze-neurodeergenerative.

IMagnesium Taurate

I-Magnesium taurine yindibaniselwano ye-magnesium kunye ne-taurine. Idibanisa izibonelelo ze-magnesium kunye ne-taurine kwaye iyongezelelekileyo ye-magnesium.
I-bioavailability ephezulu: I-Magnesium taurate ine-bioavailability ephezulu, okuthetha ukuba umzimba unokufunxa ngokulula kwaye usebenzise olu hlobo lwe-magnesium.
Ukunyamezela kwesisu esihle: Ngenxa yokuba i-magnesium taurate inezinga eliphezulu lokufunxa kwi-gastrointestinal tract, ngokuqhelekileyo ayinakwenzeka ukuba ibangele ukuphazamiseka kwesisu.

Ixhasa impilo yentliziyo: IMagnesium kunye netaurine zombini zinceda ukulawula ukusebenza kwentliziyo. I-Magnesium inceda ukugcina isigqi sentliziyo esiqhelekileyo ngokulawula ukugxilwa kwe-calcium ion kwiiseli zemisipha yentliziyo. I-Taurine ine-antioxidant kunye ne-anti-inflammatory properties, ikhusela iiseli zentliziyo kuxinzelelo lwe-oxidative kunye nomonakalo ovuthayo. Izifundo ezininzi zibonise ukuba i-magnesium taurine ineenzuzo ezibalulekileyo zempilo yentliziyo, ithoba uxinzelelo lwegazi oluphezulu, inciphisa ukubetha kwentliziyo engaqhelekanga, kunye nokukhusela kwi-cardiomyopathy.

Impilo yeNervous System: I-Magnesium kunye ne-taurine zombini zidlala indima ebalulekileyo kwinkqubo ye-nervous. I-Magnesium yi-coenzyme kwi-synthesis ye-neurotransmitters eyahlukeneyo kwaye inceda ukugcina umsebenzi oqhelekileyo wenkqubo ye-nervous. I-Taurine ikhusela iiseli ze-nerve kwaye ikhuthaza impilo ye-neuronal. I-Magnesium taurine inokuphelisa iimpawu zokuxhalaba kunye nokudakumba kwaye iphucule umsebenzi wonke wenkqubo ye-nervous. Kubantu abanexhala, ukudakumba, uxinzelelo olungapheliyo kunye nezinye iimeko ze-neurological.

I-Antioxidant kunye ne-anti-inflammatory effects: I-Taurine ineempembelelo ezinamandla ze-antioxidant kunye ne-anti-inflammatory, ezinokunciphisa uxinzelelo lwe-oxidative kunye neempendulo ezivuthayo emzimbeni. I-Magnesium ikwanceda ekulawuleni amajoni omzimba kwaye inciphisa ukudumba. Uphando lubonisa ukuba i-magnesium taurate inokunceda ukukhusela iintlobo zezifo ezingapheliyo ngokusebenzisa i-antioxidant kunye ne-anti-inflammatory properties.

Ukuphucula impilo ye-metabolic: I-Magnesium idlala indima ephambili kwi-metabolism yamandla, ukukhutshwa kwe-insulin kunye nokusetyenziswa, kunye nokulawula iswekile yegazi. I-Taurine inceda ekuphuculeni uvakalelo lwe-insulin, inceda ukulawula iswekile yegazi, kunye nokuphucula i-metabolic syndrome kunye nezinye iingxaki. Oku kwenza i-magnesium taurine isebenze ngakumbi kunezinye izongezo ze-magnesium kulawulo lwe-metabolic syndrome kunye nokumelana ne-insulin.

I-Taurine kwi-Magnesium Taurate, njenge-amino acid ekhethekileyo, nayo ineempembelelo ezininzi:

I-Taurine yi-amino acid ene-sulfure yendalo kwaye i-non-protein amino acid ngenxa yokuba ayibandakanyekanga kwi-protein synthesis njengamanye amino acids.

Eli candelo lisasazwa ngokubanzi kwizicubu zezilwanyana ezahlukeneyo, ngakumbi entliziyweni, ingqondo, amehlo kunye nezihlunu zamathambo. Ikwafumaneka kwiintlobo ngeentlobo zokutya, okufana nenyama, intlanzi, iimveliso zobisi, neziselo zamandla.

I-Taurine emzimbeni womntu inokuveliswa kwi-cysteine ​​​​phantsi kwesenzo se-cysteine ​​​​sulfinic acid decarboxylase (Csad), okanye inokufumaneka ekutyeni kwaye ifunxwe ziiseli ngokusebenzisa abathuthi be-taurine.

Njengoko iminyaka ikhula, ukuxinwa kwe-taurine kunye ne-metabolites yayo emzimbeni womntu kuya kuncipha ngokuthe ngcembe. Xa kuthelekiswa nabantu abancinci, ukuxinwa kwe-taurine kwi-serum yabantu abadala kuya kuncipha ngaphezu kwe-80%.

1. Ukuxhasa impilo yentliziyo:

Ukulawula uxinzelelo lwegazi: I-Taurine inceda ukuthoba uxinzelelo lwegazi kwaye ikhuthaze i-vasodilation ngokulawula ukulinganisela kwe-sodium, i-potassium kunye ne-calcium ion. I-Taurine inokunciphisa kakhulu amanqanaba oxinzelelo lwegazi kwizigulane ezinoxinzelelo lwegazi.

Ikhusela intliziyo: Ineempembelelo ze-antioxidant kwaye ikhusela i-cardiomyocytes kumonakalo obangelwa uxinzelelo lwe-oxidative. Ukongezwa kweTaurine kunokuphucula ukusebenza kwentliziyo kunye nokunciphisa umngcipheko wesifo senhliziyo.

2. Khusela impilo ye-nervous system:

I-Neuroprotection: I-Taurine ineempembelelo ze-neuroprotective, ukukhusela izifo ze-neurodeergenerative ngokuzinzisa i-membrane zeseli kunye nokulawula i-calcium ion concentration, ukuthintela ukugqithiswa kwe-neuronal kunye nokufa.

Isiphumo sokuzola: Ineziphumo zokuthomalalisa kunye ne-anxiolytic, inceda ukuphucula isimo sengqondo kunye nokunciphisa uxinzelelo.

3. Ukhuseleko lombono:

Ukukhuselwa kwe-retinal: I-Taurine yinxalenye ebalulekileyo ye-retina, inceda ukugcina umsebenzi we-retinal kunye nokuthintela ukuthotywa kombono.

Impembelelo ye-Antioxidant: Inokunciphisa umonakalo weeradicals zamahhala kwiiseli ze-retinal kunye nokulibaziseka kombono.

4. Impilo yeMetabolic:

Ukulawula i-glucose yegazi: i-taurine inokunceda ukuphucula uvakalelo lwe-insulin, ukulawula amanqanaba eswekile yegazi, kunye nokuthintela isifo se-metabolic syndrome.

I-Liposy metabolism: Inceda ukulawula i-lipid metabolism kunye nokunciphisa izinga le-cholesterol kunye ne-triglyceride egazini.

5. Yenza umthambo:

Ukunciphisa ukukhathala kwemisipha: I-Telonic acid inokunciphisa uxinzelelo lwe-oxidative kunye nokuvuvukala ngexesha lokuzilolonga, ukunciphisa ukukhathala kwemisipha.

Ukuphucula ukunyamezela: Kunokuphucula ukuchithwa kwemisipha kunye nokunyamezela, kunye nokuphucula ukusebenza komthambo.