Unxibelelwano phakathi koxinzelelo lweseli kunye neMitoquinone, kutheni ibalulekile kwimpilo yakho?

Kwinqanaba elilula, iseli yingxowa yolwelo ejikelezwe yi-membrane. Ayivakali ingaqhelekanga, kodwa okumangalisayo kukuba ngaphakathi kolu lwelo, ezinye iikhemikhali kunye nee-organelles zenza imisebenzi ekhethekileyo enxulumene nomsebenzi weseli nganye, njengokunceda iiseli ze-iris ezikwiliso zilawule ukuhamba kokukhanya.

Okubalulekileyo kukuba, iiseli zethu zikwafumana amafutha, njengokutya esikutyayo nomoya esiwuphefumlayo, zize ziwaguqule abe ngamandla. Okumangalisayo kukuba, iiseli zinokusebenza ngokuzimeleyo, zivelise amandla azo, kwaye ziphinde ziziphindaphinde—eneneni, iiseli zezona yunithi zincinci zobomi ezinokuphindaphindeka. Ngoko ke, iiseli azenzi nje kuphela izinto eziphilayo; zizinto eziphilayo ngokwazo.

Iiseli ezisempilweni ziyaguga, ziyazilungisa kwaye zikhula kakuhle, zivelisa amandla aneleyo okusebenza, kwaye zilawula indlela osabela ngayo kuxinzelelo ukuze umzimba wakho nengqondo yakho zisebenze kakuhle. Ngoko ke, uzigcina njani iiseli zakho ziphilile ukuqinisekisa ukuba konke oku kuhamba kakuhle?

Ndingazigcina njani iiseli zam ziphilile?

Ekubeni umzimba womntu wenziwe phantse ziiseli zonke, xa sicinga ngokuphila "okusempilweni", sithetha ngokugcina iiseli ziphilile. Ngoko ke imithetho eqhelekileyo iyasebenza: yitya ukutya okunesondlo, gcina amanqanaba afanelekileyo okuzilolonga, ungatshayi, qiniseka ukuba ulala ngokwaneleyo yonke imihla, kwaye unciphise uxinzelelo lobomi (kwakhona unciphise imfuneko yokuphendula kuxinzelelo lweseli), ukusela utywala, kunye nokuvezwa kwiityhefu ezikwindalo. Umxholo wencwadi.

Kodwa kukho amanyathelo aliqela onokuthi ungawazi, kwaye kulapho kufuneka sifunde ngakumbi ngehlabathi elimangalisayo leeseli. Kuba yonke imihla, uxinzelelo lunokwenzeka ngaphakathi kweeseli zakho, olunokuchaphazela yonke into ukusuka kumanqanaba akho amandla ukuya kwizakhono zakho zokuqonda, indlela oguga ngayo, indlela ochacha ngayo emva kokuzilolonga nokugula, kunye nempilo yakho iyonke.

Njengoko besitshilo ngaphambili, iiseli zakho zivelisa amandla azo, kodwa yintoni kanye kanye edala loo mandla? Ngaphakathi kwiiseli zakho, une-organelles ezincinci ezibizwa ngokuba yi-mitochondria. Zincinci kakhulu, kodwa zinoxanduva lokuvelisa i-90% yamandla omzimba wakho. Oko kukuthi i-90% yamandla owasebenzisa yonke imihla, kuquka ukuzilolonga ngoMvulo, ukukhumbula ukufowunela umama, ukuqala loo ngxelo ye-9pm obungafuni ukubhala, nokunceda abantwana bakho balale ngaphandle kokunyibilika. Okukhona inxalenye yomzimba wakho ifuna amandla amaninzi ukuze isebenze (njengentliziyo yakho, izihlunu, okanye ingqondo), kokukhona iiseli zayo ze-mitochondria zihlangabezana nezi mfuno zamandla aphezulu.

Ngokungathi oko bekunganelanga, i-mitochondria yakho ikwanceda iiseli zakho zikhule, ziphile, kwaye zife, zincede ekuveliseni iihomoni, zincede ekugcinweni kwe-calcium ukuze kudluliselwe imiqondiso yeeseli, kwaye zine-DNA yazo eyahlukileyo yokubanceda benze imisebenzi yabo ekhethekileyo. Kodwa ngelishwa, la ngamalungu amancinci omzimba wakho apho izinto zinokuhamba kakubi kancinci.

Yintoni uxinzelelo lweseli?

Xa i-mitochondria yakho ivelisa amandla ukuze usebenze, ikwavelisa imveliso ebizwa ngokuba yi-free radicals, efana nomsi ovela kwinjini yemoto. Ii-free radicals azimbi zonke, kwaye zidlala indima ebalulekileyo, kodwa ukuba ziqokelelana kakhulu, zinokubangela umonakalo kwiiseli. Le yeyona nto iphambili yoxinzelelo lweeseli emzimbeni (ezinye izizathu ziquka uxinzelelo lokusingqongileyo, usulelo oluthile, kunye nokwenzakala komzimba). Xa oku kusenzeka, iiseli zakho zichitha amandla axabisekileyo kunye nexesha zilwa nomonakalo, okanye ziqalise iimpendulo zoxinzelelo lweeseli, kwaye azikwazi ukwenza wonke umsebenzi obalulekileyo umzimba wakho ofuna ukuba ziwenze.

Nangona kunjalo, i-mitochondria yakho ikrelekrele – ibizwa ngokuba yindlu yamandla yeseli ngesizathu esivakalayo! Zilawula ngokwazo ukuqokelelwa kwee-free radicals ngokuvelisa ii-antioxidants, ezizinzisa ezi free radicals ziqinileyo kwaye zinciphise amathuba oxinzelelo lweseli.

I-mitochondria yakho ayiphucuki ngokuhamba kweminyaka. Njengoko ukhula, amanqanaba e-antioxidant emzimbeni wakho ayehla ngokwendalo, nto leyo ebangela ukuba ii-free radicals zingalawuleki. Ukongeza, ubomi bethu bemihla ngemihla busibeka kwi-free radicals ezininzi ngenxa yezinto ezibangela uxinzelelo ezifana nongcoliseko, imitha ye-UV, ukutya okungafanelekanga, ukungazilolongi, ukungalali kakuhle, ukutshaya, uxinzelelo lobomi, kunye nokusetyenziswa kotywala, nto leyo eyenza kube nzima ukulwa nee-free radicals.

Uxinzelelo lweeseli luthetha ukuba iiseli zakho zihlaselwa - kulapho "ukwaluphala nobomi" kungena khona. Yonke imihla, iiseli zakho zisengozini yokonakala kukulahlekelwa zii-antioxidants ngexesha lokwaluphala kunye neminye imonakalo eyenzeka "ubomi bonke."

Kutheni ufanele ukhathazeke ngoxinzelelo lweseli?

Olu dibaniso lwezinto ezingaphakathi nezingaphandle luyenza buthathaka iseli ukuba ikwazi ukumelana nayo. Endaweni yokusebenza kakuhle, iiseli zethu ziya zixinezeleka ngakumbi, oko kuthetha ukuba sisoloko sikwimeko yokulwa nomlilo ukuze imizimba yethu isebenze kakuhle. Kuthi, oku kuthetha ukuziva sidiniwe ngakumbi, sinamandla aphantsi emva kwemini, sinengxaki yokugxila emsebenzini, sizive sidiniwe ngosuku olulandelayo emva kokuzilolonga okunzima, siphila kancinci emva kokugula, kwaye siziva okanye sibona imiphumo yokwaluphala icaca ngakumbi. Ngamanye amazwi, ivakala imbi.

Kuyavakala ke ngoko ukuba ukuba iiseli zakho zisemagqabini, nawe uya kuba semagqabini. Iitriliyoni zeeseli emzimbeni wakho zakha isiseko sempilo yakho. Xa iiseli zakho ziphilile, kubakho isiphumo esihle se-domino, kubandakanya nokuvuselela impendulo yakho yomzimba yokuzikhusela, exhasa impilo yomzimba wakho wonke ukuze ukwazi ukuphila ubomi bakho ngokwenene.

I-Mitoquinone inceda njani ukulwa noxinzelelo lweseli?

Uxinzelelo lweeseli lwenzeka xa iiseli zethu zichaphazeleka zizinto eziphazamisa ukusebenza kwazo okuqhelekileyo. Oku kunokuquka uxinzelelo lwe-oxidative, oluvela xa kukho ukungalingani phakathi kokuveliswa kwee-free radicals eziyingozi kunye nokukwazi komzimba ukuzithambisa. Ukongeza, iityhefu zokusingqongileyo, ukutya okungafanelekanga, kunye noxinzelelo lwengqondo zonke zinokuba negalelo kuxinzelelo lweeseli. Xa iiseli zethu ziphantsi koxinzelelo, kunokukhokelela kwiingxaki ezahlukeneyo zempilo, kubandakanya ukwaluphala ngokukhawuleza, ukudumba, kunye nomngcipheko ophezulu wezifo ezingapheliyo ezifana nesifo sentliziyo, isifo seswekile, kunye neengxaki ze-neurodegenerative.

I-Mitoquinone, uhlobo olukhethekileyo lwe-Coenzyme Q10, ivele njengesixhobo esinamandla ekulweni noxinzelelo lweseli. Ngokungafaniyo nee-antioxidants zemveli, i-Mitoquinone yenzelwe ngokukodwa ukujolisa nokuqokelelana ngaphakathi kwe-mitochondria, amandla amakhulu eeseli zethu. Oku kubalulekile kuba i-mitochondria isengozini enkulu yomonakalo we-oxidative, kwaye ukungasebenzi kakuhle kwayo kunokuba nemiphumo emikhulu kwimpilo yethu. Ngokunikezela ngokhuseleko olujoliswe kwi-antioxidant kwi-mitochondria, i-Mitoquinone inceda ukugcina umsebenzi wayo olungileyo kwaye iyikhusele kwimiphumo eyonakalisayo yoxinzelelo.

Njengoko sele kufundiwe, i-mitochondria yakho ifuna amanqanaba aphezulu ee-antioxidants ukuze kuthintelwe ii-free radicals ezininzi kunye neeproteni zoxinzelelo ukuba zingabi nkulu kwaye zibangele umonakalo, kodwa amanqanaba endalo omzimba wakho ayawa njengoko ukhula.

Ngoko ke thatha nje izongezo ze-antioxidant? Ngelishwa, ii-antioxidants ezininzi kunzima ukuzifunxa ukusuka emathunjini ziye egazini kwaye zinkulu kakhulu ukuba zingangena kwi-membrane yangaphakathi ye-mitochondrial, ekhetha kakhulu ukufunxa ii-antioxidants.

Izazinzulu zethu zisemsebenzini wokoyisa imingeni yokufunxwa kwe-antioxidant okusebenzayo. Ukuze benze oku, batshintshe isakhiwo se-molecular se-antioxidant CoQ10 (eveliswa ngokwendalo kwi-mitochondria kwaye isetyenziselwa ukuvelisa amandla nokulawula ii-free radicals), besenza sibe ncinci kwaye bongeza i-positive charge, beyitsala kwi-negative charge ye-mitochondria. Nje ukuba ifike apho, iMitoquinone iqala ukulinganisela ngempumelelo ii-free radicals kwaye incede ekunciphiseni uxinzelelo lweseli, ukuze iiseli zakho (kunye nawe) zizive zixhaswa. Sithanda ukuyicinga njengomsebenzi wendalo.

Ngenkxaso yeIMitoquinone,i-mitochondria yakho, kunye neeseli zisebenza ngokupheleleyo, kuquka ukuvelisa iimolekyuli ezibalulekileyo ngokwendalo ezifana ne-NAD kunye ne-ATP, ukunceda iiseli zigcine impilo entle kunye namandla apheleleyo namhlanje, ngomso, nakwixesha elizayo.

I-Mitoquinone iqala ukusebenza ukususela ngexesha efakwa kwiiseli, inciphisa uxinzelelo lweeseli. Iingenelo ziyanda imihla ngemihla njengoko iiseli ezininzi zivuselelwa, nto leyo ephumela kwimpilo engcono kunye namandla. Nangona abanye abantu beya kubona iziphumo kwangethuba, emva kweentsuku ezingama-90 iiseli zakho ziya kuvuselelwa ngokupheleleyo kwaye uya kufikelela kwinqanaba apho umzimba wakho uya kuziva unamandla, ulungelelene, kwaye uhlaziyekile.