I-Spermidine luhlobo lwendalo lwepolyamine olufumaneka kuzo zonke iiseli eziphilayo. Idlala indima ebalulekileyo kwimisebenzi yeselula, kuquka ukukhula kweeseli, ukwanda, kunye nokwahlula. I-Spermidine yenziwe emzimbeni ukusuka kwenye i-polyamine ebizwa ngokuba yi-purescine, ebandakanyeka kwiinkqubo ezahlukeneyo zezinto eziphilayo, kubandakanywa ukuzinza kwe-DNA, i-gene expression, kunye ne-cell metabolism.
Ziziphi iingenelo zespermidine?
①I-Spermidine inokulinganisa i-caloric restriction kwaye ibonelele ngeenzuzo zokuzila ukutya;
②I-Spermidine inokuphucula i-autophagy, idlala indima "kwi-detoxification" yeeseli, kwaye isebenze iziteshi ezininzi zokulwa nokuguga - ukuvimbela i-mTOR kunye nokuvula i-AMPK, ngaloo ndlela i-anti-aging;
③Ukonyusa umthamo we-spermidine kunokunceda ukuxhathisa umhlaza, isifo seswekile, isifo sentliziyo kunye ne-neurodegeneration;
④Olunye uphando lubonisa ukuba i-spermidine inokukhuthaza ukukhula kweenwele.
I-Sub-ejaculation & autophagy
Iinzuzo zezempilo kunye nexesha elide lokuthintelwa kwekhalori ngokuzila ukutya ziyaziwa, kodwa ngenxa yokuba abantu abambalwa abakwazi ukunamathela ekuzileni okuzinzileyo, izibonelelo zabo zempilo ezipheleleyo zingalahleka.
Okanye i-caloric restriction mimetics efana ne-spermidine inokusetyenziselwa ukulinganisa imeko yokuzila kwaye ufumane izibonelelo zempilo ezifanayo ngaphandle kweziphumo ebezingalindelekanga zendlala ixesha elide.
Ngokukhawulezisa i-autophagy, i-spermidine inokusebenzisa izibonelelo ezininzi zempilo.
Ngokomzekelo, i-Autophagy, icingelwa ukukhusela ukuvuvukala kunye noxinzelelo lwe-oxidative, ngaloo ndlela inciphisa umngcipheko wezifo ezinxulumene neminyaka (kubandakanywa nomhlaza, isifo se-metabolic, isifo senhliziyo, kunye nezifo ze-neurodeergenerative) kunye nokufa.
Ukongeza ekukhuseleni izifo ezinxulumene neminyaka, i-spermidine inokuphucula iinkalo ezininzi zomzimba zokuguga, kunye nenye yeempawu ezibonakalayo zokuguga ezivela kwimibimbi kunye namabala ebusweni bethu.
Ulusu lolona lungu likhulu lomzimba womntu kwaye luqulunqwe ziintlobo ezahlukeneyo zeeseli, ezibandakanya i-lipids, i-keratin, kunye ne-sebum, esebenza njengomqobo okhuselayo ngokuchasene neendawo zangaphandle ezinzima.
Uphononongo olwenziwe ebantwini kwisakhiwo solusu lomntu kunye nomsebenzi womqobo ubonise iziphumo zokuchasa ukuguga kwe-spermidine eluswini.
Ivela phi i-spermidine?
Emzimbeni womntu, kukho imithombo emithathu ephambili ye-spermidine:
①Yenziwa ngumzimba womntu ngokwawo
Inokuba ukusuka kwi-arginine ukuya kwi-ornithine ukuya kwi-purescine ukuya kwi-spermidine, okanye inokuguqulwa kwi-spermine
②Iphuma ngokuthe ngqo ekutyeni
③Ivela ekudibaneni kweentyatyambo zamathumbu
Indlela yokunyusa amanqanaba e-spermidine
01. Ukungeniswa kwe-precursors ye-spermidine
Ukungeniswa kwe-spermidine precursors kunokunyusa umxholo we-spermidine, kwaye zombini i-arginine kunye ne-spermine ingaba nefuthe.
Ukutya okutyebileyo kwe-Arginine ngokuyinhloko kumantongomane, imbewu kunye nemifuno, kunye ne-turkey, ngelixa ukutya okucebileyo kwe-spermine kubandakanya ingqolowa yengqolowa, isibindi senkukhu, iintliziyo zenkukhu kunye namathumbu enyama.
02. Gcina i-methylation enempilo
Ngokucacileyo, ukugcina i-methylation enempilo kubalulekile kwi-spermidine synthesis.
Ukwenziwa kwe-spermidine kufuna ukuthatha inxaxheba kwe-dcSAMe, ephuma kwi-SAMe.
I-SAMe yeyona coenzyme ibaluleke kakhulu kwi-methylation yabantu, kwaye amanqanaba ayo achaphazelekayo ngumjikelezo we-methylation.
03. Ifunyenwe ekutyeni
Kakade ke, eyona ndlela ingqalileyo kukufumana i-spermidine ekutyeni. Ukutya okutyebileyo kwi-spermidine kungundoqo wezilwanyana kunye nezityalo, ezifana nentsholongwane yengqolowa, iimbotyi, imbewu, iinkumba kunye nesibindi sezilwanyana (ewe, intsholongwane yengqolowa iqulethe i-gluten) ye).
04. Izongezo zeSpermidine
Nangona imizimba yethu inokuvelisa i-spermidine, iphinda ifumaneke kukutya okuthile, ukwenza ukutya okudliwayo kube yinto ebalulekileyo yokugcina amanqanaba afanelekileyo. Ukutya okutyebileyo kwi-spermidine kubandakanya itshizi ezindala, amakhowa, iimveliso zesoya, iimbotyi, iinkozo, kunye neziqhamo ezithile kunye nemifuno. Nangona kunjalo, ukuxinwa kwe-spermidine koku kutya kunokwahluka, okukhokelela abantu abaninzi ukuba bathathele ingqalelo izongezo njengendlela yokunyusa ukutya kwabo.
Apho unokufumana khona umgangatho we-spermidine
Kwi-biotechnology yanamhlanje kunye namashishini amayeza, i-spermidine (i-spermidine), njenge-amine ebalulekileyo ye-biogenic, iye yatsala ingqalelo enkulu ngenxa yendima yayo ephambili ekukhuleni kweeseli, ukwanda kunye neenkqubo zokuguga. Njengoko uphando kwimpilo kunye nokuphila ixesha elide luqhubeka, imfuno ye-spermidine iyaqhubeka ikhula. Nangona kunjalo, umgangatho we-spermidine kwimarike awulingani, kwaye indlela yokufumana i-spermidine ephezulu ibe yinto ekugxilwe kuyo abaphandi abaninzi besayensi kunye neenkampani.
Ulwazi olusisiseko lweSpermidine
Ubume bekhemikhali be-spermidine bulula, kunye nenombolo ye-CAS ye-124-20-9. Imisebenzi yayo emininzi yebhayoloji kwiiseli iyenza imolekyuli ebalulekileyo ekugugeni, i-autophagy kunye nophando lwe-antioxidant. Uphando lubonisa ukuba i-spermidine inokukhuthaza i-cell autophagy, ilibazise inkqubo yokuguga, kwaye iphucule amandla e-antioxidant yeeseli kwinqanaba elithile. Ke ngoko, ukufumana i-spermidine ecocekileyo kubalulekile kuphando lwesayensi kunye nokusetyenziswa.
Izinto ezilungileyo zeSuzhou Myland
Phakathi kwababoneleli abaninzi bedlozi, iSuzhou Myland ibalasele ngomgangatho wayo wemveliso ogqwesileyo kunye neenkonzo zobungcali. I-spermidine ebonelelwa nguSuzhou Mylanduyeinombolo ye-CAS ye-124-20-9 kunye nokucoceka okungaphezulu kwe-98%. Le mveliso yococeko oluphezulu ayihambelani kuphela nemigangatho yamazwe ngamazwe, kodwa iphinda ivavanye umgangatho ongqongqo wokuqinisekisa ukuba ibhetshi nganye yeemveliso inokuhlangabezana neemfuno zophando lwezenzululwazi kunye nezicelo zamashishini.
1. Ukuqinisekiswa koMgangatho
I-Suzhou Myland iyazi ukuba umgangatho wemveliso lilitye lembombo lokusinda kunye nophuhliso lweshishini. Inkampani inezixhobo zokuvelisa eziphambili kunye nenkqubo engqongqo yokulawula umgangatho wokuqinisekisa ukuba i-spermidine iye yavavanywa ngokungqongqo kunye nokuqinisekiswa. Ingaba kukuthengwa kwezinto eziluhlaza okanye yonke inkalo yenkqubo yokuvelisa, iSuzhou Myland izama ukufezekisa ukugqwesa kunye nokuqinisekisa ukucoceka okuphezulu kunye nomgangatho ophezulu weemveliso.
2. Inkxaso yobuchwephesha yobugcisa
Ukongeza ekuboneleleni ngespermidine ekumgangatho ophezulu, iSuzhou Myland ikwabonelela abathengi ngenkxaso yobuchwephesha yobuchwephesha. Nokuba kukusetyenziswa kwemveliso, iimeko zokugcina, okanye uyilo lovavanyo olunxulumeneyo, iqela lobugcisa benkampani linokubonelela abathengi ngesikhokelo esineenkcukacha kunye neengcebiso. Le nkonzo enenkathalo ayiphuculi nje ukwaneliseka kwabathengi, kodwa inyusa ukuthembela kwabathengi kwimveliso.
3. Ixabiso lokukhuphisana
Kwisiseko sokuqinisekisa umgangatho wemveliso, iSuzhou Myland nayo izibophelele ekuboneleleni abathengi ngamaxabiso akhuphisanayo. Ngokuphucula iinkqubo zemveliso kunye nolawulo lwekhonkco lokubonelela, inkampani iyakwazi ukunciphisa ngokufanelekileyo iindleko, ngaloo ndlela idlulisela amaxabiso afikelelekayo kubathengi. Oku kwenza ukuba amaziko ophando lwezenzululwazi angaphezulu kunye namashishini afumane i-spermidine ekumgangatho ophezulu ngamaxabiso afanelekileyo kwaye ikhuthaze inkqubela phambili yophando olunxulumeneyo.
Indlela yokuthenga
Ukuba ujonge i-spermidine ekumgangatho ophezulu,Suzhou Mylandngokungathandabuzekiyo lukhetho oluthembekileyo. Unokufumana ulwazi oluninzi ngewebhusayithi esemthethweni yenkampani okanye uqhagamshelane neqela lokuthengisa ngokuthe ngqo. Nokuba ziimfuno zovavanyo ezincinci okanye usetyenziso lwemizi-mveliso emikhulu, iSuzhou Myland inokubonelela ngezisombululo eziguquguqukayo ngokweemfuno ezithile zabathengi.
Ukuziphendulela: Eli nqaku lelolwazi ngokubanzi kuphela kwaye akufanele lithathwe njengeliphi na icebiso lonyango. Olunye ulwazi lweposti yebhlog luvela kwi-Intanethi kwaye alunamsebenzi. Le webhusayithi inoxanduva kuphela lokuhlela, ukufomatha kunye nokuhlela amanqaku. Injongo yokudlulisa ulwazi olongezelelekileyo ayithethi ukuba uyavumelana neembono zayo okanye uqinisekise ubunyani bomxholo wayo. Soloko udibana nengcali yezempilo ngaphambi kokuba usebenzise naziphi na izongezo okanye wenze utshintsho kwirejimeni yokhathalelo lwempilo.
Ixesha lokuposa: Oct-17-2024