I-Spermidine, i-compound yendalo, ifumene ingqwalasela enkulu ngenxa yokukwazi ukukhupha i-autophagy, enokunceda iiseli zisuse iiprotheyini ezinobungozi kunye nenkunkuma yeselula, ngaloo ndlela ikhuthaza ukuvuselelwa kweeseli kunye nokuphucula impilo yonke. Kweli nqaku Kwisikhokelo sethu esibanzi se-spermidine, makhe sijonge ngakumbi unxibelelwano phakathi kwe-spermidine kunye nempilo yethu!
Ngoko ke, yintoni i-spermidine? Ithathwe kwigama lesiGrike elithi "sperma", elithetha imbewu, i-spermidine ifumaneka ngokubanzi kwimithombo yezityalo ezifana neembotyi zesoya, ii-ertyisi, amakhowa kunye neenkozo ezipheleleyo. Ikwafumaneka kwiintshizi ezindala eziye zabiliswa kunye nenkqubo yokuguga ekhokelela kumazinga aphezulu e-spermidine.
I-Spermidine yi-aliphatic polyamine. I-Spermidine synthase (SPDS) ibangela ukubunjwa kwayo kwi-purescine. Sisandulela sezinye iipolyamines ezifana ne-spermine kunye ne-isomer pyrospermine yayo yesakhiwo.
Njengepolyamine ngokwemvelo, i-spermidine idlala indima ebalulekileyo kwimisebenzi eyahlukeneyo yeselula. Ifumaneka kuzo zonke izinto eziphilayo ukusuka kwiibhaktheriya ukuya kwizityalo kunye nezilwanyana, kwaye ininzi kakhulu kwiiseli zomntu.
Ukufumana amanqanaba aneleyo e-spermidine ngokutya kuphela kulucelomngeni. Kwiminyaka yakutshanje, uphando kule khompawundi eziphilayo kukhokelele ekuvelisweni izongezo spermidine. Ezi zongezelelo zibonelela ngendlela efanelekileyo kunye nethembekileyo yokuqinisekisa ukuthathwa kwe-spermidine eyaneleyo, ngakumbi abo bangenakho ukufikelela kukutya okucebileyo kwe-spermidine.
1. Ukuphucula isakhono se-autophagy
I-Autophagy yinkqubo ejongene nokususwa kwezinto ezonakalisiweyo okanye ezingafunekiyo zeselula kwaye ibalulekile ekugcineni impilo yeselula kunye nomsebenzi.
I-Spermidine ifunyenwe ukuvuselela i-autophagy, ukukhuthaza ukupheliswa kwezinto ezinobungozi kunye nokuphucula ukunyaniseka kwamaselula. Oku, kuye kwadityaniswa nomngcipheko oncitshisiweyo wezifo ezinxulumene neminyaka, njengezifo ze-neurodeergenerative kunye neentlobo ezithile zomhlaza.
2. Unempembelelo ethile ye-cardioprotective.
Izifundo ezininzi zibonise ukuba i-spermidine inokunceda ukunciphisa uxinzelelo lwegazi, ukunciphisa umngcipheko wesifo senhliziyo, kunye nokuphucula impilo yenhliziyo.
I-Spermidine yenza oku ngokuthintela ukuqokelelwa kwamafutha emithanjeni yegazi, ukunciphisa ukuvuvukala nokukhuthaza ukuvuselelwa kweeseli zentliziyo eyonakalisiweyo. Ngokufaka i-spermidine ekutyeni kwethu, sinokuzikhusela kwizifo ezinxulumene nentliziyo.
3. Ibonisa isithembiso ekukhuthazeni impilo yengqondo.
Ukuguga kudla ngokunxulunyaniswa nokwehla komsebenzi wokuqonda, okukhokelela kwizifo ezifana ne-dementia kunye nesifo sika-Alzheimer.
Nangona kunjalo, i-spermidine yafunyanwa ukuchasana nale miphumo ngokukhusela i-neurons kuxinzelelo lwe-oxidative kunye nokuphucula ukusinda kwabo jikelele.
Izifundo kwiimodeli zezilwanyana ziye zabonisa ukuba ukuxhaswa nge-spermidine kunokulibazisa ukuhla okunxulumene neminyaka kwimemori nokufunda. Ke ngoko, ukusebenzisa amandla e-spermidine kunokuvula indlela yeendlela ezintsha zokuthintela kunye nokungenelela kwizifo ze-neurodeergenerative.
Ngezantsi kukho imithombo yokutya ephezulu ye-spermidine onokufuna ukucinga ngayo ukongeza kwisondlo sakho ukunyusa ukutya kwakho kwe-spermidine.
1. Intsholongwane yengqolowa
Iqulethe umxholo ophezulu we-spermidine. Ngokuqhelekileyo kusetyenziswa njenge-topping kwi-cereal okanye i-yogurt, ukongeza intsholongwane yengqolowa ekudleni kwakho kwasekuseni yindlela elula yokuvuna inzuzo ye-spermidine.
2. Isoya
Ayisiyiyo kuphela i-soy ukhetho oluhle kakhulu lweprotheni yemifuno, kodwa iqulethe i-spermidine eninzi. Ukwazisa iimveliso zesoya ezifana ne-tofu, i-tempeh okanye i-edamame kwisidlo sakho yindlela ebalaseleyo yokunyusa ukutya kwakho kule khompawundi enenzuzo.
3. Amakhowa
I-Shiitake, i-portobello mushroom, kunye ne-oyster mushroom zityebile ngokukodwa kule khompawundi. Ezi zithako eziguquguqukayo zingasetyenziswa kwiindidi ezahlukeneyo zokutya ukusuka kwi-frys ukuya kwiisuphu, ukubonelela ngendlela emnandi kunye nesondlo sokwandisa ukusetyenziswa kwe-spermidine.
4. Okunye
Okunye ukutya okutyebileyo kwe-spermidine kubandakanya imifuno efana nelentile, i-chickpeas kunye nee-ertyisi eziluhlaza, kunye neziqhamo ezithile ezifana ne-grapefruit, iiorenji kunye namapere. Ngokubandakanya oku kutya kukutya kwakho, unokonyusa ngokwendalo ukutya kwakho kwe-spermidine kwaye unokuba neziphumo zokukhuthaza impilo.
Nangona uphando malunga ne-spermidine lusaqhubeka, iziphumo zokuqala zithembisa. Kuyafaneleka ukuba uqaphele ukuba amanqanaba e-spermidine anokwahluka ngokusekelwe kwizinto ezifana nokulungiswa kokutya, ukuvuthwa, kunye nendlela yokupheka. Ke ngoko, ukwandisa ukutya, kuyacetyiswa ukuba utye oku kutya kwezona ndlela zintsha nezincinci zicutshungulwayo.
Uninzi lwabantu alucacanga kakhulu malunga nomahluko phakathi kokufumana i-spermidine ekutyeni okanye ukusebenzisa izongezo ze-spermidine ngokuthe ngqo, makhe sijonge umahluko kunye!
1. Izongezelelo zibonelela ngendlela efanelekileyo yokunyusa amanqanaba e-spermidine, ngakumbi abo basokola ukufumana okwaneleyo ngokutya kwabo rhoqo. Izongezelelo ze-Spermidine zihlala zivela kwimithombo yendalo kwaye ziza ngeendlela ezahlukeneyo, njengee-capsules okanye umgubo. Ezi zongezo zihamba kwinkqubo yokugxila kwi-spermidine, okwenza kube lula ukufumana iidosi eziphezulu kunokutya kuphela.
2. Xa utya ukutya okutyebileyo kwi-spermidine, uyazuza kwi-synergy yezinye izondlo ezikhoyo kwi-matrix yokutya, ephucula ukufunxa kwayo kunye neenzuzo zempilo iyonke. Kwakhona, imithombo yokutya ihlala ibonelela ngeemali eziphantsi ze-spermidine xa kuthelekiswa nezongezo, kodwa ziseluncedo.
3. I-supplement inikezela nge-dose ephezulu kunye neyomgangatho we-spermidine, evumela indlela ejoliswe ngakumbi esekelwe kwiimfuno zomntu ngamnye. Oku kuluncedo ngakumbi kubantu abafuna izibonelelo zempilo ezithile ze-spermidine okanye kubantu abathile abathintela ukutya kwabo okutyebileyo kwe-spermidine ngenxa yothintelo lokutya.
Ukukhetha ukufumana i-spermidine ekutyeni okanye izongezo zixhomekeke kukhetho lomntu kunye nemeko. Kubantu abaninzi, ukutya okunokulinganisela okubandakanya ukutya okucebileyo kwi-spermidine kufuneka kunikeze amanqanaba aneleyo ale khompawundi enenzuzo. Nangona kunjalo, kwabo bafuna ugxininiso oluphezulu okanye abajongene nezithintelo zokutya, ukongezwa kunokuba lulongezelelo oluxabisekileyo.
Ukumisela idosi efanelekileyo ye-spermidine kuxhomekeke kwizinto ezininzi, kubandakanywa iminyaka, impilo jikelele, kunye neziphumo ezithile ezifunwayo.
Okwangoku, akukho kuthathwa kwansuku zonke kucetyiswayo (RDI) kwi-spermidine. Uphononongo lubonisa imiphumo enenzuzo kwiidosi ze-1 ukuya kwi-10 mg ngosuku. Nangona kunjalo, kuhlala kucetyiswa ukuba udibane nengcali yezempilo ngaphambi kokufaka i-spermidine kwindlela yakho yemihla ngemihla.
Imithombo yokutya yendalo ibonelela nge-spermidine kwaye ingaba yongezwa ngokugqwesileyo ekudleni kwakho. Ukutya okunjengentsholongwane yengqolowa, iziqhamo ezithile (igrapefruit, iidiliya, neeorenji), itshizi, iimbotyi zesoya, amakhowa, kwanewayini esele ikhulile ziqulethe isixa esikhulu sespermidine. Ukubandakanya oku kutya kukutya okunokulinganisela kunokunceda ukwandisa ukungena kwe-spermidine ngokwemvelo.
Izongezo zikwayindlela yokukhetha kwabo bafuna ukutya okongeziweyo kwe-spermidine. Izongezelelo zeSpermidine ziza ngeendlela ezininzi, kubandakanywa iipilisi kunye nomgubo. Izongezo ezikumgangatho ophezulu kufuneka zivele kubavelisi abathembekileyo ababambelela kwimigangatho engqongqo yolawulo lomgangatho.
Xa uqala ukuxhaswa kwe-spermidine, kucetyiswa ukuba uqale ngedosi ephantsi. Ukuqala malunga ne-1 mg ngosuku kwaye ngokuthe ngcembe ukwandisa umthamo kwiiveki ezininzi kunokunceda ukuphepha iziphumo ebezingalindelekanga.
Nangona i-spermidine ibonakala ikhuselekile ngokubanzi kwaye inyamezeleke kakuhle, abanye abantu banokufumana iziphumo ezincinci zesisu ezifana nokuqunjelwa okanye isisu esibuhlungu xa songezwa okokuqala nge-spermidine. Ukuba ezi mpawu ziyaqhubeleka okanye ziba mandundu, kufuneka kudityanwe nengcali yezempilo.
Umbuzo: Kuthatha ixesha elingakanani ukuba i-spermidine isebenze?
A: Ixesha elithatha i-spermidine ukuba isebenze kwaye ivelise iziphumo ezibonakalayo zingahluka ngokusekelwe kwizinto ezininzi, kubandakanywa iminyaka yomntu, impilo yonke, i-dosage, kunye nobude bokuncedisa. Ngokuqhelekileyo, ukuqhubeka kwe-spermidine supplementation kungafuneka iiveki ezininzi okanye iinyanga ngaphambi kokuba umntu aqale ukuqaphela naluphi na utshintsho olubalulekileyo.
Ukuziphendulela: Eli nqaku lenzelwe iinjongo zolwazi kuphela kwaye akufanele lithathwe njengengcebiso yezonyango. Soloko udibana nengcali yezempilo phambi kokuba usebenzise naziphi na izongezo okanye utshintshe irejimeni yokhathalelo lwempilo yakho.
Ixesha lokuposa: Jun-28-2023
