I-N-acetyl-L-cysteine ethyl ester, ekwabizwa ngokuba yi-NACET, i-antioxidant enamandla kunye nesongezelelo esidumileyo kwiinzuzo zayo zempilo ezinokubakho.Ngokhetho oluninzi kwimarike, ukukhetha esona songezo se-NACET kunokuba nzima.Ukukunceda wenze isigqibo esinolwazi kwaye ukhethe isongezelelo se-NACET esikumgangatho ophezulu esihlangabezana neenjongo zakho zempilo kunye nokuba sempilweni.Kufuneka uqwalasele ngononophelo umgangatho, i-bioavailability, idosi, ukuqulunqwa, isidima, kunye nexabiso.Ngokuqwalasela ezi meko kunye nokwenza uphando olucokisekileyo, unokwenza isigqibo esinolwazi malunga nokukhetha isongezelelo esisempilweni nesikumgangatho ophezulu we-NACET.
I-NACET, mfutshane yeN-acetyl-L-cysteine ethyl ester, yindlela eyongezelelweyo ye-cysteine, i-amino acid eyimfuneko.Kuthathwa njengento ebaluleke kakhulu kuba umzimba wakho unokuvelisa kwezinye ii-amino acids, ezizezi: methionine kunye ne-serine.Kuyimfuneko kuphela xa ukutya kwe-methionine kunye ne-serine kuphantsi.I-cysteine ifumaneka kuninzi lokutya okuneprotheyini ephezulu, njengenkukhu, i-turkey, iyogathi, itshizi, amaqanda, imbewu kajongilanga kunye neembotyi.Iyaziwa ngokuba namandla okulwa ne-antioxidant kunye nokukwazi ukuxhasa yonke imiba yezempilo, i-NACET ingaphezulu nje kwesongezelelo, yifomula enamandla ye-antioxidant eyilelwe ukomeleza kakhulu ingqondo kunye nempilo yomzimba.
Yintoni eyahlula i-NACET kubukho bayo obuphezulu be-bioavailability, obuphindwe ngama-20 ngaphezu kwe-glutathione eqhelekileyo kunye ne-NAC supplements.Oku kuthetha ukuba xa uthatha i-NACET, umzimba wakho uyisebenzisa ngokufanelekileyo.Kwaye oku kuphuculwa kwe-bioavailability kuguqulela kwiziphumo ezisebenzayo ze-antioxidant, ngakumbi ekunyuseni amanqanaba e-antioxidant glutathione, eyaziwa njengeyona antioxidant inamandla emzimbeni.
I-NACET inceda ukukhusela isibindi kuxinzelelo lwe-oxidative kwaye ikhuthaza impilo kunye nomsebenzi wayo jikelele.Ayigcini nje ukunceda ukukhusela ingqondo kumonakalo owenziwe simahla, ikwaxhasa umsebenzi wokuqonda, iyenza ibe ngumhlobo ogqibeleleyo wempilo yengqondo yexesha elide.
I-NACET ikwaphononongelwe amandla ayo okuxhasa impilo yokuphefumla.Ihlala isetyenziswa njenge-mucolytic, oku kuthetha ukuba inceda ukuphuka kunye ne-mucus encinci, okwenza kube lula ukusula kwindlela yokuphefumula.
I-NACET idibanisa izithako ezikumgangatho ophezulu, ezixhaswa luphando kunye nokuzibophelela kwimpilo, okwenza kube ngaphezu kokongeza nje.Kwaye ngophando olungaphaya kunye nokuqonda, i-NACET inokuqhubeka isisixhobo esinamandla sokukhuthaza impilo kunye nokuphila kakuhle.
I-NACET yindlela ye-ethyl ester ye-N-acetyl L-cysteine (NAC) kwaye isebenza emzimbeni ngokusebenzisa indlela ekhethekileyo yokusebenza, ejoliswe kwindima yayo njenge-precursor ye-glutathione kunye namandla ayo aphezulu xa kuthelekiswa ne-NAC eqhelekileyo ye-bioavailability.
Iguqulelwe kwi-N-Acetyl Cysteine (NAC): Emva kokuba ityiwe, i-NACET ifunxelwa egazini.Ngenxa yeqela le-ethyl ester, i-lipophilic ngakumbi (i-fat soluble) kwaye inokuthi ifakwe ngcono kwi-lipid membrane yeeseli.Emzimbeni, i-NACET iguqulwa ibe yi-N-acetylcysteine (NAC).
Yandisa amanqanaba e-glutathione: I-NAC isandulela se-glutathione, enye yezona zinto zibalulekileyo ze-antioxidants emzimbeni.I-Glutathione idlala indima ebalulekileyo ekunciphiseni i-radicals yamahhala, ukunciphisa uxinzelelo lwe-oxidative kunye nokuxhasa iinkqubo zokuchithwa kwesibindi.Ngokunyusa amanqanaba e-glutathione, i-NACET inceda ukukhusela iiseli kumonakalo we-oxidative, obalulekileyo ekugcineni impilo yeeseli kunye nokuthintela umonakalo onxulumene neminyaka.
Ukulawulwa kwe-Neurotransmitter Activity and Inflammation: I-NACET, ngokuguqulwa kwayo kwi-NAC, inokuchaphazela amanqanaba e-glutamate kwingqondo.I-Glutamate yi-neurotransmitter ebalulekileyo ebandakanyekayo ekufundeni nasekukhumbuleni.Kwakhona ineempawu ezichasayo.I-NAC ibonakaliswe ukulawula ukuveliswa kwee-cytokines ezithile, ezibonisa iamolekyu ezidibanisa kunye nokulawula i-immunity, ukuvuvukala, kunye ne-hematopoiesis.
Isenzo se-Mucolytic: I-NAC, ifom esebenzayo evela kwi-NACET, isebenza njenge-agent ye-mucolytic ngokuphula iibhondi ze-disulfide kwi-mucus, iyenza ibe yi-viscous encinci kwaye kulula ukuyikhupha.Oku kuthetha ukuba kunceda ukuqhawula kunye ne-mucus encinci, okwenza kube lula ukusula kwindlela yokuphefumla.Oku kuluncedo ngakumbi kubantu abaneemeko zokuphefumla ezifana ne-bronchitis engapheliyo, i-asthma, okanye i-cystic fibrosis.
N-acetyl-L-cysteine ethyl ester,eyaziwa ngokuba yi-NACET, i-antioxidant eyaziwayo kunye ne-modified form ye-N-acetyl-L-cysteine (NAC).I-NACET kukholeleka ukuba ine-bioavailability ephezulu kunye nozinzo kunezongezelelo ze-NAC zemveli.Oku kuthetha ukuba inokufunxwa lula ngumzimba kwaye ibe neziphumo ezihlala ixesha elide.Usenokuba uvile nge-NAC kuba isisandulela se-antioxidant glutathione enamandla.
I-NACET yahluke ngokupheleleyo kwiNAC yesintu.I-NACET yinguqulelo eqinisekisiweyo ye-NAC eye yatshintshwa ukuze idale i-NACET ekulula ukuyifunxa kwaye kunzima ukuyichonga.Ayisiyiyo kuphela inguqulo ye-ethyl ester efumaneka kakhulu kune-NAC, kodwa iyakwazi nokuchwechwela esibindini nasezintso kwaye iwele umqobo wegazi-ingqondo.Ukongeza, i-NACET inekhono elikhethekileyo lokukhusela kumonakalo we-oxidative xa ihanjiswa kuwo wonke umzimba ngeeseli ezibomvu zegazi.
Olunye uphando lubonise ukuba i-NACET ingena ngokukhawuleza kwiiseli kwaye ibanjwe ukuvelisa i-NAC kunye ne-cysteine.I-NACET ifumaneka kwiiseli kwizicubu ezahlukeneyo, kubandakanya nengqondo, ngenxa yokukwazi ukuwela umqobo wegazi-ubuchopho.Olunye uphando lubonise ukuba i-NAC inokuwela umqobo wegazi-ingqondo, kodwa ngamanani amancinci, kwaye izinga lokufunxa ngomlomo limalunga ne-3-6 kuphela.Izinga lokufunxa kwe-NACET lisenokudlula kwi-60%, kwaye ingena kwiiseli kunokuba iphume ngaphandle kwazo, kwaye ingene ngakumbi ebuchotsheni.Nje ukuba i-NACET ingene kwiiseli, iguqulwa ibe yi-NAC, i-cysteine, kwaye ekugqibeleni i-glutathione.Emva koko, i-antioxidant glutathione inceda i-detoxify kwaye ilawule ukusebenza kwe-immune eqhelekileyo, inceda ekulungiseni iiseli, kwaye ixhasa ukuguga kunye nokusebenza kwengqondo.
Enye ipropathi esebenzayo ye-NACET kukukwazi kwayo ukudlula isisu kwaye ingafunxwa ngamathumbu.Umzimba wakho uyaliqonda ixabiso le-cysteine kwi-NAC kwaye uyifunxa esiswini, esibindini, okanye kwizintso-ukugcina i-cysteine kwiiseli ze-epithelial (iiseli ezibeka imithambo yomzimba kunye namalungu angenanto) endaweni yokuyiyeka ingene ebuchotsheni kunye nezinye. iindawo ezifunekayo!Ngenxa ye-ethyl ester eyongezelelweyo, i-NACET ayaziwa njenge-NAC, eyivumela ukuba ihambe egazini iye kuyo yonke ikroba lomzimba ukuya kwindawo yayo yokugqibela efunekayo.
I-NACET luhlobo olongezelelweyo lwe-cysteine.Ukufumana i-NACET eyaneleyo kubalulekile ngenxa yezizathu ezininzi zempilo:
1. Inkxaso ye-Antioxidant: Ukuqokelela kunye ne-oxidation ye-radicals yamahhala emzimbeni yimbangela enkulu yezifo ezininzi kunye nokuphazamiseka kwengqondo.Ukungakwazi komzimba wethu ukucima ezi tyhefu kubangelwa yimiba yemfuza (i-methylation engafanelekanga), ukutya okungalunganga, uxinzelelo, kunye ne-toxins yendawo.I-NACET ibonakala ibonelela umzimba ngendlela esebenzayo ngakumbi yokunceda ukubuyisela impilo yethu yomzimba neyengqondo.Ngokunciphisa iimolekyuli ezinobungozi, i-NACET inokunceda ukunciphisa umngcipheko wesifo esingapheliyo kunye nokuxhasa impilo yonke yeselula.
2. Impilo yesibindi: I-NACET ibonise ukuxhasa umsebenzi wesibindi ngokukhuthaza ukuveliswa kwe-glutathione, eyona nto ibalulekileyo ekwakheni nasekulungiseni izicubu.Njenge-antioxidant enamandla, i-glutathione ikhusela umonakalo we-oxidative kwaye ixhasa impilo yeselula yengqondo, intliziyo, imiphunga kunye nawo onke amanye amalungu kunye nezicubu.I-Glutathione idlala indima ebalulekileyo kwi-detoxification, enenzuzo ngakumbi kubantu abanokuthi bavelele kwi-toxins yendalo okanye abanembali yeengxaki zesibindi.
3. IMpilo yoMphefumlo: I-NACET ifundelwe amandla ayo okuxhasa impilo yokuphefumula, ngakumbi kubantu abaneemeko ezifana ne-bronchitis engapheliyo, i-asthma, kunye nesifo esingapheliyo se-pulmonary obstructive.Iimpawu zayo ze-mucolytic zinokunceda ukuphula i-mucus kunye nokuphucula ukuphefumla.
4. Impilo yengqondo: I-NACET idityaniswe nempilo yengqondo ephuculweyo, kunye nezifundo ezibonisa ukuba inamandla okuxhasa ulungelelwaniso lweemvakalelo kunye nokunciphisa iimpawu zokuxhalaba kunye nokudakumba.Ukukwazi kwayo ukulawula amanqanaba e-glutamate kwingqondo kunokuba negalelo kwimiphumo emihle kwimpilo yengqondo.
5. Inkxaso ye-Immune: I-NACET ibonakaliswe ukunyusa ukusebenza komzimba ngokuxhasa imveliso ye-glutathione kunye nokukhuthaza impendulo ephilileyo yokuvuvukala.Oku kunokunceda umzimba ukuba ukhuseleke ngcono kusulelo kunye nokugcina impilo yonke yomzimba.
6. UmSebenzi wokuSebenza: Abadlali bezemidlalo kunye nabathandi bempilo banokuzuza kwi-NACET yokuncedisa ngenxa yokunciphisa uxinzelelo lwe-oxidative eyenziwa ngumzimba kunye nokuxhasa ukubuyiswa kwemisipha.Inokukunceda ukuphucula ukunyamezela kunye nokusebenza kwezemidlalo ngokubanzi.
7. Impilo yolusu: Iipropathi ze-NACET ze-antioxidant zikwanceda impilo yolusu, inceda ukuthintela ukonakala kweradical yasimahla kunye nokunciphisa iimpawu zokuguga.
1. Umgangatho kunye nobunyulu: Xa ukhetha isongezelelo se-NACET, kubalulekile ukubeka phambili umgangatho kunye nokucoceka.Jonga iimveliso ezenziwe kwizibonelelo eziqinisekisiweyo ze-GMP kunye nomntu wesithathu ovavanyelwe ubunyulu kunye namandla.Oku kuqinisekisa ukuba ufumana isongezelelo somgangatho ophezulu ngaphandle kokungcola okanye ukungcola.
2. I-Bioavailability: Khetha izongezo ze-NACET ezinokufumaneka kwe-bioavailability eyandisiweyo.Oku kuthetha ukuba isongezelelo sifunxwa ngokulula kwaye sisetyenziswe ngumzimba ngokusebenza okuphezulu.
3. Umthamo kunye nokuManzisa: Nika ingqalelo kwithamo kunye nokuxinana kwe-NACET kwisongezelelo sakho.Idosi ecetyiswayo ye-NACET inokwahluka ngokweemfuno zomntu kunye neenjongo zempilo.Kubalulekile ukukhetha idosi efanelekileyo yokongeza ehlangabezana neemfuno zakho ezithile.Ukongeza, ugxininiso oluphezulu lwe-NACET lunokubonelela ngezibonelelo ezinamandla ngakumbi, ke qwalasela amandla owufunayo xa ukhetha.
4. Uqulunqo: Qwalasela uqulunqo lwesongezelelo sakho se-NACET.Ezinye iimveliso zisenokuba nezithako ezongezelelweyo okanye iikhompawundi ze-synergistic ukomeleza ukusebenza kwe-NACET.Ngokomzekelo, izongezo eziqulethe ezinye i-antioxidants okanye izondlo ezifana ne-vitamin C okanye i-selenium inokubonelela ngenkxaso eyongezelelweyo kwimpilo yonke.
5. Isidima noPhononongo: Phanda ngebhrendi kwaye ufunde uphononongo lwabathengi phambi kokuthenga izongezo zeNACET.Khangela inkampani ehloniphekileyo enerekhodi yokuvelisa izongezo ezikumgangatho ophezulu.Uphononongo lwabathengi lunokubonelela ngezimvo ezixabisekileyo ekusebenzeni kwemveliso kunye nomgangatho, kukunceda wenze isigqibo esinolwazi.
6. Ixabiso kunye neXabiso: Ngelixa ixabiso lingafanelanga ukuba libe yiyona nto ithatha isigqibo, kubalulekile ukuqwalasela ixabiso elipheleleyo le-supplement.Thelekisa ixabiso ngenkonzo nganye kunye nomgangatho wemveliso ukuze uqiniseke ukuba ufumana isivumelwano esihle.Gcina ukhumbula ukuba ukutyala imali kwisongezelelo somgangatho ophezulu we-NACET kunokubonelela ngeenzuzo ezinkulu ekuhambeni kwexesha.
7. Qhagamshelana nochwepheshe bezempilo: Ngaphambi kokuqala nayiphi na irejimeni entsha yokuncedisa, kusoloko kucetyiswa ukuba udibane nochwepheshe bezempilo, ngakumbi ukuba unayo nayiphi na imeko yezempilo ephantsi okanye uthatha amayeza.Banokukunika iingcebiso ezilungiselelwe wena kwaye baqinisekise ukuba i-NACET ikhuselekile kwaye izilungele iimfuno zakho.
I-Suzhou Myland Pharm & Nutrition Inc. ibandakanyeke kwishishini lokongezelela isondlo ukususela ngo-1992. Yinkampani yokuqala e-China ukuphuhlisa nokuthengisa isicatshulwa sembewu yomdiliya.
Iminyaka engama-30 yamava kwaye iqhutywa bubuchwephesha obuphezulu kunye nesicwangciso se-R&D esiphuculwe kakhulu, inkampani iphuhlise uluhlu lweemveliso ezikhuphisanayo kwaye ibe sisongezelelo sesayensi yobomi, ukuhlanganiswa kwesiko kunye nenkampani yeenkonzo zokuvelisa.
Ukongeza, iSuzhou Myland Pharm & Nutrition Inc. ikwangumvelisi obhalisiweyo we-FDA.Izixhobo ze-R&D zenkampani, izixhobo zemveliso, kunye nezixhobo zohlalutyo zezanamhlanje kwaye zinemisebenzi emininzi, kwaye zinokuvelisa iikhemikhali ukusuka kwimilligrams ukuya kwiitoni kwisikali, kwaye zithobela imigangatho ye-ISO 9001 kunye neenkcukacha zemveliso ye-GMP.
Umbuzo: Ziziphi izinto ezimele ziqwalaselwe xa ukhetha i-N-Acetyl-L-Cysteine Ethyl Ester yokongeza kwiimfuno zakho?
A: Xa ukhetha isongezelelo se-N-Acetyl-L-Cysteine Ethyl Ester, qwalasela izinto ezifana nomgangatho wemveliso, ukucoceka, iingcebiso zedosi, izithako ezongezelelweyo, kunye nodumo lomkhiqizo okanye umenzi.Kukwabalulekile ukudibana negcisa lezempilo phambi kokuba uyisebenzise.
Umbuzo: Ndingawuvavanya njani umgangatho kunye nokucoceka kwe-N-Acetyl-L-Cysteine Ethyl Ester supplement?
A: Ukuvavanya umgangatho kunye nokucoceka kwe-N-Acetyl-L-Cysteine Ethyl Ester yongezelela ngokujonga iimveliso ezivavanyelwe amandla kunye nokucoceka komntu wesithathu.Ukongeza, qwalasela isidima somenzi kunye nokubambelela kwabo kwiiNdlela eziLungileyo zoMveliso (GMP).
Umbuzo: Ndingayidibanisa njani i-N-Acetyl-L-Cysteine Ethyl Ester eyongezelelweyo kwindlela yam yokuphila kakuhle?
A: I-N-Acetyl-L-Cysteine Ethyl Ester eyongezelelweyo inokudityaniswa kwi-wellness routine ngokulandela i-dosage ekhuthazwayo enikezelwa yimveliso.Kubalulekile ukuqwalasela iinjongo zempilo yomntu ngamnye kwaye udibane nengcali yezempilo ukuba kuyimfuneko.
Ukuziphendulela: Eli nqaku lelolwazi ngokubanzi kuphela kwaye akufanele lithathwe njengeliphi na icebiso lonyango.Olunye ulwazi lweposti yebhlog luvela kwi-Intanethi kwaye alunamsebenzi.Le webhusayithi inoxanduva kuphela lokuhlela, ukufomatha kunye nokuhlela amanqaku.Injongo yokudlulisa ulwazi olongezelelekileyo ayithethi ukuba uyavumelana neembono zayo okanye uqinisekise ubunyani bomxholo wayo.Soloko udibana nengcali yezempilo ngaphambi kokuba usebenzise naziphi na izongezo okanye wenze utshintsho kwirejimeni yokhathalelo lwempilo.
Ixesha lokuposa: Jun-17-2024
