I-Choline alfoscerate, ekwabizwa ngokuba yi-Alpha-GPC, iye yaba sisongezo esidumileyo sokuphucula ingqondo. Kodwa ngeendlela ezininzi ezikhethiweyo apho, ukhetha njani i-choline alfoscerate powder supplement? I-choline i-alfoscerate ye-powder supplements engcono kakhulu ye-2024 idinga ukuqwalaselwa ngokucophelela kobunyulu, idosi, i-brand reputation, ixabiso, kunye nezinye izithako. Ngokuqwalasela ezi zinto, unokufumana isongezelelo somgangatho ophezulu oxhasa impilo yakho yengqondo kwaye kukunceda ufezekise iinjongo zakho zempilo. Ngaphambi kokuba uqale naluphi na isongezelelo esitsha, hlala unxibelelana nengcali yezempilo ukuze uqiniseke ukuba lolona khetho lufanelekileyo kuwe.
Alpha GPCsisishunqulelo se-alpha-glycerophosphocholine, ekwabizwa ngokuba yi-glycerophosphocholine. I-phospholipid equkethe i-choline kwaye yenye yezona zinto ziphambili zeembrane zeseli. Inomxholo ophezulu we-choline. Ngokumalunga ne-41% yobunzima be-Alpha GPC yi-choline. I-Choline isetyenziselwa ukubonakaliswa kweeseli kwingqondo kunye nezicubu ze-nervous, kwaye izongezo ze-Alpha GPC zihlala zidibaniswa nezinye iikhompawundi ezibizwa ngokuba yi-nootropics. I-Nootropics yiklasi yeziyobisi kunye / okanye izongezo ezinceda ukuxhasa kunye nokuphucula umsebenzi wokuqonda.
Yintoni i-choline?
Umzimba uvelisa i-alpha GPC kwi-choline. I-Choline sisondlo esiyimfuneko esifunwa ngumzimba ukuze sibe sempilweni. Nangona i-choline ayiyiyo i-vitamin okanye i-mineral, ihlala ihambelana neevithamini ze-B ngenxa yeendlela ezifanayo zomzimba emzimbeni.
I-Choline iyadingeka kwi-metabolism eqhelekileyo, isebenza njenge-methyl donor, kwaye ide idlale indima ebalulekileyo ekuveliseni i-neurotransmitters ethile njenge-acetylcholine.
I-Choline sisondlo esibalulekileyo esifumaneka ngokwemvelo kubisi lwebele lomntu kwaye yongezwa kwifomula yorhwebo yosana.
Nangona umzimba uvelisa i-choline esibindini, akwanele ukuxhasa iimfuno zomzimba. Ukuveliswa kwe-choline enganeleyo emzimbeni kuthetha ukuba i-choline kufuneka ifunyenwe ekudleni. Ukunqongophala kwe-Choline kunokwenzeka ukuba ukutya kwe-choline yokutya akwanelanga.
Izifundo ziye zadibanisa ukusilela kwe-choline kwi-atherosclerosis okanye ukuqina kwemithambo, isifo sesibindi, kunye nokuphazamiseka kwengqondo. Ngaphezu koko, kuqikelelwa ukuba abantu abaninzi abakutyi ukutya okwaneleyo ekutyeni kwabo.
Nangona i-choline ifumaneka ngokwemvelo kukutya okufana nenkomo, amaqanda, i-soy, i-quinoa, kunye namazambane abomvu, ukuncedisa i-alpha GPC kunokunceda ngokukhawuleza ukwandisa amanqanaba e-choline emzimbeni.
I-Glycerylphosphocholine ikwasetyenziswa ngokubanzi kuphando lwezonyango kunye ne-biochemical kunye nezicelo zonyango.
1. Ukufumanisa kunye nophando lokuqala: I-Glycerylphosphocholine yafunyanwa okokuqala yi-biochemist yaseJamani uTheodor Nicolas Lyman ekuqaleni kwekhulu le-19. Waqala wawahlulahlula loo nto kumthubi weqanda, kodwa ukwakheka kwawo nomsebenzi wawo wawungekaqondwa ngokupheleleyo.
2. Ukuchongwa kwesakhiwo: Ekuqaleni kwenkulungwane ye-20, izazinzulu zaqala ukufunda ubume be-glycerophosphocholine nzulu ngakumbi, kwaye ekugqibeleni zagqiba ukuba iqulethe i-glycerol, i-phosphate, i-choline kunye neentsalela ezimbini ze-asidi ezinamafutha. Ezi ziqendu zidityaniswe ngeendlela ezithile ngaphakathi kwimolekyuli ukwenza iimolekyuli ze-phospholipid.
3. Imisebenzi ye-Biological: Kancinci kuyaqatshelwa ukuba i-glycerophosphocholine idlala indima ebalulekileyo kwi-biology, ngakumbi ekwakhiweni nasekugcinweni kweembrane zeseli. Kubalulekile kwi-fluidity kunye nokuzinza kweembrane zeseli kwaye kuneempembelelo ekuboniseni, ukunxibelelana kwe-intercellular, kunye ne-synthesis ye-choline.
Umqondiso weseli
Imizimba yethu yenza imisebenzi emininzi kwinqanaba leeselula yonke imihla ngaphandle kokuyiqonda. Okufana nokuhamba kwegazi kunye nokubetha kwentliziyo. Izigidi zeeseli ziyanxibelelana ukuze zinike umzimba amandla okugqiba le misebenzi nokusebenza kakuhle. Olu nxibelelwano luphakathi kweeseli lubizwa ngokuba yi "cell signing". Iimolekyuli ezininzi zezithunywa zithumela imiqondiso phakathi kweeseli ezifana neefowuni.
Nanini na xa iiseli zithetha enye kwenye, impembelelo yombane ibangela ukukhutshwa kwee-neurotransmitters kwindawo ebizwa ngokuba yi-synapse. Ii-Neurotransmitters zihamba ukusuka kwi-synapses kwaye zibophe kwi-receptors kwi-dendrites, ezifumana kwaye ziqhube ulwazi abalufumanayo.
I-PGC-1α ibonakaliswa kumanqanaba aphezulu kwi-mitochondria kunye neendawo ezithile ze-metabolism esebenzayo. Ezi ziquka ingqondo, isibindi, i-pancreas, izihlunu zamathambo, intliziyo, inkqubo yokugaya kunye nenkqubo ye-nervous.
Kuyaziwa ukuba ngexesha lokuguga, i-mitochondria yeselula yi-organelles eyonakaliswe kakhulu. Ke ngoko, ukucocwa kunye ne-mitochondrial biogenesis (ukwenza i-mitochondria entsha) ibalulekile ekulinganiseni imetabolism yamandla. I-PGC-1α idlala indima ebalulekileyo kwinkqubo yokulwa nokuguga. Uphando lubonisa ukuba i-PGC-1α ikhusela i-atrophy ye-muscle ngokulawula i-autophagy (ukucoca iiseli). Izifundo zezilwanyana zibonisa ukuba amanqanaba akhulayo e-PGC-1α anokuphucula iimeko ezahlukeneyo zemisipha. Injongo yethu kukunceda ukwandisa amanqanaba ePGC-1α.
Kwi-2014, abaphandi bafunda izilwanyana ezivelisa i-PGC-1α engaphezulu kwimicu yemisipha kunye nolawulo olungazange luvelise i-PGC-1α engaphezulu. Kuphando, izilwanyana zibonakaliswe kwiimeko eziphezulu zoxinzelelo. Siyazi ukuba uxinzelelo ngokubanzi lunokunyusa umngcipheko wokudakumba. Kwafunyaniswa ukuba izilwanyana ezinamazinga aphezulu e-PGC-1α zomelele kwaye zikwazi ukujamelana neempawu zokudakumba kunezo zinezinga eliphantsi le-PGC-1α. Ke ngoko, olu phononongo lucebisa ukuba ukusebenza kwe-PGC-1α kunokuphucula imo.
I-PGC-1α nayo inefuthe elithile lokukhusela kwimisipha. I-Myoblasts luhlobo lweseli yezihlunu. Uphononongo lubonisa ukubaluleka kwendlela ye-PGC-1α-mediated kunye nendima yayo kwi-atrophy ye-skeletal muscle. I-PGC-1α ivuselela i-biogenesis ye-mitochondrial inxalenye ngokuphakamisa i-NRF-1 kunye ne-2. Uphononongo luye lwabonisa ukuba i-PGC-1α ecacileyo ye-muscle ibalulekile kwi-atrophy ye-skeletal muscle (ukunciphisa umthamo kunye nobuthathaka). Ukuba umsebenzi we-PGC-1α mitochondrial ye-biological pathway yanda, umonakalo we-oxidative uyancipha. Ngoko ke, i-PGC-1α icingelwa ukuba idlala indima yokukhusela ekunciphiseni ukuchithwa kwemisipha ye-skeletal.
Nrf2 indlela yomqondiso
(Nrf-2) yinto elawulayo enceda ukukhusela kwii-oxidants zeselula ezinobungozi kwiiseli. Ilawula ukubonakaliswa kweendlela ezingaphezulu kwama-300 ekujoliswe kuzo ukunceda imetabolism, ukunyusa ukhuseleko lwe-antioxidant kunye nokunceda ukuphendula komzimba. Izifundo zebhubhoratri zibonisa ukuba ukusebenzisa i-Nrf-2 kunokwandisa ixesha lokuphila ngokuthintela i-oxidation.
I-Alpha GPC yonyusa amanqanaba e-acetylcholine kwingqondo. I-acetylcholine iyimfuneko kwimemori kunye nokusebenza kwengqondo kunye nokubonisa phakathi kwee-neurons kwiindawo ezahlukeneyo zobuchopho. Amaqanda, intlanzi, amantongomane, i-cauliflower, i-broccoli kunye nezongezelelo ezinomsoco ziyimithombo ecebileyo ye-choline.
Ukusukela okoalpha GPCiveliswa emzimbeni, i-metabolized to phosphatidylcholine. I-Phosphatidylcholine, eyona nto iphambili ye-lecithin, ifumaneka kuzo zonke iiseli emzimbeni kwaye isetyenziswa ngeendlela ezininzi ezahlukeneyo zokuxhasa umzimba, kubandakanya impilo yesibindi, impilo ye-gallbladder, imetabolism, kunye nokuveliswa kwe-neurotransmitter acetylcholine.
I-Acetylcholine sisithunywa sekhemikhali esivumela iiseli zemithambo-luvo ukuba zinxibelelane nezinye iiseli zemithambo-luvo, iiseli zemisipha, kunye namadlala. I-Acetylcholine iyimfuneko kwimisebenzi emininzi, kubandakanywa nokulawula ukubetha kwentliziyo, ukugcina uxinzelelo lwegazi, kunye nokulawula ukunyakaza ngaphakathi kwamathumbu.
Ngelixa ukusilela kwe-acetylcholine ngokuqhelekileyo kunxulunyaniswa ne-myasthenia gravis, amanqanaba aphantsi e-neurotransmitter nawo adityaniswe nenkumbulo embi, ubunzima bokufunda, ithoni yemisipha ephantsi, i-dementia kunye nesifo se-Alzheimer.
Uphando lubonisa ukuba i-alpha-GPC inceda ukunyusa i-acetylcholine kwingqondo kuba ifunxa ngokukhawuleza kwaye iwela ngokulula umqobo wegazi-ingqondo.
Obu buchule bunika i-alpha GPC ezinye izibonelelo zempilo ezikhethekileyo, ezinjengokuncedisa ukomeleza inkumbulo, ukomeleza ukuqonda, ukuphucula ukusebenza kwezemidlalo, kunye nokwandisa ukukhuselwa kwehomoni yokukhula.
1. I-Alpha GPC kunye nezincedisi zememori
Uphando lubonisa ukuba i-alpha GPC inokunceda ukuxhasa umsebenzi wememori kunye nokwakheka ngenxa yobudlelwane bayo ne-acetylcholine. Ekubeni i-acetylcholine ibalulekile ekubunjweni kwememori kunye nokugcinwa, i-alpha GPC inokunceda ukukhuthaza ukubunjwa kwememori.
Uphononongo lwezilwanyana olubandakanya iigundane lufumene ukuba ukuxhaswa kwe-alpha GPC kuncede ukuphucula umsebenzi wememori ngelixa ukhusela ingqondo kwimiphumo eyingozi yoxinzelelo.
Olunye uphononongo lwezilwanyana lwafumanisa ukuba ukongeza nge-alpha GPC kunceda ekuphuculeni ukukhula kweeseli zengqondo kunye nokuthintela ukungena kweeseli zengqondo kunye nokufa emva kokuxhuzula.
Ebantwini, kuqhutywe izifundo ezininzi zokuvavanya ukuxhaswa kwe-alpha GPC kwimemori kunye nokukwazi ukuqaphela amagama kubantu abanokulahlekelwa kokuva okunxulumene neminyaka.
Nangona kunjalo, olunye uphando olubandakanya abathathi-nxaxheba be-57 abaneminyaka eyi-65 ukuya kwi-85 bafumanisa ukuba ukuxhaswa nge-alpha GPC kuphuculwe kakhulu amanqaku okuqatshelwa kwamagama kwiinyanga ze-11. Iqela lolawulo elingazange lifumane i-alpha GPC linomsebenzi wokuqonda igama elibi. Ukongeza, iziphumo ebezingalindelekanga ezimbalwa zichazwe kwiqela usebenzisa i-alpha GPC ngexesha lokufunda.
Ngelixa i-alpha GPC inokunceda ukukhulisa inkumbulo, uphando lubonisa ukuba inokunceda ekuphuculeni ubuchule bokuqonda ngokupheleleyo.
2. I-Alpha GPC kunye nokuphuculwa kwengqondo
Uphando lucebisa ukuba i-alpha GPC inokunceda ukuphucula kunye nokuphucula amandla okuqonda ngaphaya kokuveliswa kwenkumbulo.
Ngokomzekelo, uphando oluthile oluyimfama oluphindwe kabini, olungahleliwe, olulawulwa yi-placebo lubandakanya ngaphezu kwe-260 yabathathi-nxaxheba besilisa nabasetyhini abaneminyaka eyi-60 ukuya kwi-80 abaye bafumanisa ukuba banesifo se-Alzheimer esincinci ukuya kwimodareyitha. Abathathi-nxaxheba bathatha i-alpha GPC okanye i-placebo kathathu imihla ngemihla ngeentsuku ze-180.
Kwiintsuku ze-90, uphando lufumene ukuphuculwa okubalulekileyo ekusebenzeni kwengqondo kwiqela le-alpha GPC. Ekupheleni kophononongo, iqela le-alpha GPC libonise ukuphucuka ngokubanzi kumsebenzi wokuqonda kodwa ukuncipha kwe-Global Deterioration Scale (GDS) amanqaku. Ngokuchaseneyo, amanqaku kwiqela le-placebo ahlala efana okanye aba mandundu. I-GDS luvavanyo lokuhlola olunceda ababoneleli bezempilo ukuba bahlole imeko yomntu yesifo sengqondo esiyingozi.
Olunye uphononongo lufumene ukuba ukuxhaswa kwe-alpha GPC kunokunceda ukucotha ukuhla kwengqondo kubantu abadala abanengxaki yoxinzelelo lwegazi. Uphononongo lubandakanya abathathi-nxaxheba abadala be-51 abahlulwe bangamaqela e-2. Elinye iqela lafumana izongezo ze-alpha GPC, ngelixa elinye iqela lingazange. Kwiinyanga ezi-6 zokulandelelana, uphando lufumene ukuphuculwa okubalulekileyo kwizakhono zengqondo kwiqela le-alpha GPC. Uphononongo lubonisa ukuba i-alpha-GPC iphucula ingqibelelo yemithambo yegazi kunye nokukhula, inceda ekwandiseni i-perfusion yengqondo kunye nokuphucula ukusebenza kwengqondo.
Ngelixa i-alpha GPC inokunceda ukuphucula izakhono zengqondo, uphando lubonisa ukuba inokunceda ukuphucula ukusebenza kwezemidlalo.
3. I-Alpha GPC kunye nokuphucula ukusebenza kweembaleki
Nangona uphando lubonisa ukuba i-alpha GPC inokuzuza ukuqonda, uphando lubonisa ukuba le nootropic emangalisayo ingaba noluhlu olubanzi lweenzuzo zomzimba.
Uphando lubonisa ukuba ukongeza nge-alpha GPC kunokunceda ukuphucula ukusebenza kwezemidlalo kunye namandla. Ngokomzekelo, uphando olulawulwa yi-placebo oluyimfama oluphindwe kabini lubandakanya amadoda ekholeji ye-13 athatha i-alpha GPC kwiintsuku ze-6. Abathathi-nxaxheba bagqibe imithambo eyahlukeneyo eyahlukeneyo, kubandakanya imithambo ye-isometric kumzimba ongasentla nasezantsi. Uphando lufumene ukuba ukuxhaswa kwe-alpha GPC kuphucula amandla e-isometric ngaphezu kwe-placebo.
Olunye uphando oluyimfama oluphindwe kabini, olungenamkhethe, olulawulwa yi-placebo lubandakanya abadlali bebhola bebhola ekhatywayo bekholeji ye-14 abaneminyaka eyi-20 ukuya kwi-21 iminyaka. Abathathi-nxaxheba bathatha izongezelelo ze-alpha GPC kwiyure eyi-1 phambi kokuba benze uthotho lwemithambo, kubandakanywa ukutsiba okuthe nkqo, imithambo yeisometric, kunye nokufinyela kwemisipha. Uphando lufumene ukuba ukongeza nge-alpha-GPC ngaphambi kokuzivocavoca kunokunceda ukwandisa isantya sokuphakamisa iintsimbi. Uphando luye lwafumanisa ukuba ukongeza nge-alpha GPC kunokunceda ukunciphisa ukudinwa okunxulumene nomthambo.
Uphando lubonisa ukuba i-alpha GPC ayincedi nje ukuphucula ukusebenza kwezemidlalo kodwa inokunceda ukwandisa imveliso yehomoni yokukhula.
4. I-Alpha GPC kunye nokunyuka kwe-hormone yokukhula
Ihomoni yokukhula komntu, okanye iHGH ngokufutshane, yincindi yedlala eveliswa lidlala lepituitary ebuchotsheni. I-HGH iyimfuneko kwimpilo jikelele kubantwana nakubantu abadala. Ebantwaneni, i-HGH inoxanduva lokunyusa ukuphakama ngokukhuthaza ukukhula kwamathambo kunye ne-cartilage.
Kubantu abadala, i-HGH inokunceda ukukhuthaza impilo yamathambo ngokwandisa ukuxinana kwamathambo kunye nokuxhasa izihlunu eziphilileyo ngokuphucula ukukhula kwemisipha. I-HGH yaziwa ngokuphucula ukusebenza kwezemidlalo, kodwa ukusetyenziswa ngokuthe ngqo kwe-HGH ngenaliti kuvaliwe kwimidlalo emininzi.
Ngenxa yokuba imveliso ye-HGH ngokwemvelo iqala ukuncipha kubomi obuphakathi, oku kunokukhokelela ekuqokeleleni kwamafutha esisu, ukulahleka kwemisipha, amathambo aphukileyo, impilo ephantsi yentliziyo, kunye nomngcipheko wokufa.
Uphando lubonisa ukuba ukuxhaswa kwe-alpha GPC kunokunceda ukukhuthaza ukwanda kwehomoni yokukhula, nakubantu abadala abaphakathi.
Uphononongo oluphindwe kabini oluyimfama, olungahleliwe, olulawulwa yi-placebo lubandakanya amadoda angama-7 aneminyaka eyi-30 ukuya kwiminyaka eyi-37 abenza ukuphakamisa ubunzima kunye nokuqeqeshwa kokumelana emva kokuncedisa i-alpha GPC. Uphononongo lufumene ukuba ukongeza i-alpha GPC phambi koqeqesho lobunzima kunye nokuxhathisa umthambo kwandisa ukugcinwa kwehomoni yokukhula ngokuphindwe kangama-44, endaweni ye-2.6 nje.
Ukonyuka kwemveliso ye-HGH kubomi obuphakathi bunxulunyaniswa namafutha omzimba ancitshisiweyo, ukuzuza okukhulu kwezihlunu, kunye nokusebenza kwengqondo okuphuculweyo.
Alpha GPCisongezelelo se-choline esifumaneka ngokulula esinokunceda ukuphucula inkumbulo, ukuphucula ukuqonda, ukwandisa ukusebenza kwehlabathi lokwenyani, kunye nokwandisa imveliso yehomoni yokukhula kunye nokukhuselwa.
Ukubandakanya i-alpha GPC kwindlela esempilweni yemihla ngemihla kunokubonelela ngeenzuzo zobomi bonke engqondweni nasemzimbeni kwaye kukhuthaze impilo yonke kwiminyaka ezayo.
Iindawo zesicelo:
1. Unyango lwezonyango: I-Choline Alfoscerate isetyenziselwa amayeza ukunyanga isibindi esinamafutha, izifo ezithile ze-neurological, izifo ze-cardiovascular, njl. Akukona nje ukubonelela ngamanqanaba aphezulu e-choline efunekayo kwiiseli zengqondo kunye neeseli ze-nerve, zikhusela iindonga zabo zeeseli. Izigulane ezine-Alzheimer's disease zibonakaliswa ngokuhla kwememori kunye nokusebenza kwengqondo, kwaye zihamba kunye neengxaki ezahlukeneyo, ezifana nokunciphisa ukuhamba, ukuphazamiseka kwe-neurological kunye nezinye izithintelo zokusebenza. Iziphumo zovavanyo lwezonyango lwezonyango kunye nezilingo zeklinikhi ziye zaqinisekisa ukuba i-glycerophosphocholine iluncedo kakhulu kwisakhono sokuqonda kunye nokusebenza kwengqondo kwengqondo. Ikwanazo nosetyenziso olunokwenzeka kwiinkqubo zokuhanjiswa kweziyobisi, inceda amachiza ukuba awele inwebu yeeseli ngokufanelekileyo.
2.I-Cosmetic: I-Choline Alfoscerate isoloko isetyenziswa kwiinaliti zokuthambisa ukuphucula inkangeleko yolusu.
1.Ipiracetam
I-Piracetam yenye yeyona nootropics endala kunye neyona idumileyo. Yeyosapho lwe-racemic kwaye ihlala isetyenziselwa ukukhulisa umsebenzi wokuqonda kunye nenkumbulo.
I-Mechanism: I-Piracetam imodareyitha i-acetylcholine ye-neurotransmitter kwaye iphucula unxibelelwano lwe-neuronal.
Iinzuzo: Isetyenziselwa kakhulu ukuphucula inkumbulo, amandla okufunda kunye nokugxila.
I-Cons: Abanye abasebenzisi babika ukuba iziphumo zePiracetam zibuqili kwaye zingadinga ukupakishwa kunye nezinye i-nootropics ukufumana inzuzo ebonakalayo.
Ukuthelekisa: Nangona zombini i-Alpha GPC kunye nePiracetam ziphucula umsebenzi wokuqonda, i-Alpha GPC inefuthe elithe ngqo kumanqanaba e-acetylcholine kwaye inokubonelela ngeenzuzo ezicacileyo ngakumbi kwimemori nokufunda.
2. Noopept
I-Noopept liyeza elinamandla le-nootropic elaziwa ngeempawu zalo zokuphucula ingqondo. Idla ngokuthelekiswa nepiracetam kodwa ithathwa njengenamandla.
I-MECHANISM: I-Noopept yandisa amanqanaba e-brain-derived neurotrophic factor (BDNF) kunye ne-nerve growth factor (NGF), exhasa impilo yengqondo kunye nokusebenza kwengqondo.
Iingenelo: Isetyenziselwa ukuphucula inkumbulo, ukufunda, kunye nokukhusela i-neuroprotection.
Ukungalungi: I-Noopept inokubangela imiphumo ethile, njengentloko kunye nokucaphuka.
Ukuthelekisa: I-Noopept kunye ne-Alpha GPC zombini zineempembelelo zokuphucula ingqondo, kodwa indlela ye-Noopept ibandakanya izinto ze-neurotrophic, ngelixa i-Alpha GPC igxile kwi-acetylcholine. Kwabo bajonge ngokukodwa ukonyusa amanqanaba e-acetylcholine, iAlpha GPC inokuba ngcono.
3. L-Theanine
I-L-theanine yi-amino acid efumaneka kwiti eyaziwayo ngeziphumo zayo zokuthomalalisa kunye nokukwazi ukomeleza ukugxila ngaphandle kokubangela ukozela.
I-Mechanism: I-L-theanine yonyusa amanqanaba e-GABA, i-serotonin kunye ne-dopamine, ikhuthaza ukuphumla kunye nokuphucula isimo sengqondo.
Iingenelo: Isetyenziselwa ukunciphisa ukuxhalaba, ukuphucula ukugxila, kunye nokuphucula isimo sengqondo.
I-Cons: I-L-theanine ngokuqhelekileyo inyamezeleke kakuhle, kodwa iziphumo zayo zibuqili kunezinye i-nootropics.
Uthelekiso: L-Theanine kunye ne-Alpha GPC zinosetyenziso olwahlukileyo. I-Alpha GPC igxile kakhulu ekwandiseni ukusebenza kwengqondo nge-acetylcholine, ngelixa i-L-theanine ifaneleka ngakumbi ukuphumla kunye nokuphucula isimo sengqondo. Ziyancedisana xa zisetyenziswa kunye.
4. I-Modafinil
I-Modafinil isiyobisi esikhuthaza ukuvuswa ngokuqhelekileyo sisetyenziselwa ukuphatha ukuphazamiseka kokulala. Ikwayinto eyaziwayo njengento yokuphucula ingqondo.
I-Mechanism: I-Modafinil ichaphazela ama-neurotransmitters amaninzi, kuquka i-dopamine, i-norepinephrine, kunye ne-histamine, ukukhuthaza ukuvuka kunye nokusebenza kwengqondo.
Iingenelo: Isetyenziselwa ukuphucula ukuphaphama, ukugxila, kunye nobuchule bokuqonda.
Ukungalungi: I-Modafinil inokubangela imiphumo emibi njengokungalali, ukuxhalaba, kunye neentloko. Ikwaliyeza elibhalwe ngugqirha kumazwe amaninzi.
Ukuthelekisa: I-Modafinil kunye ne-Alpha GPC zombini ziphucula umsebenzi wokuqonda, kodwa ngeendlela ezahlukeneyo. I-Modafinil ingaphezulu malunga nokukhuthaza ukuphaphama kunye nokuphaphama, ngelixa i-Alpha GPC igxile kwi-acetylcholine kunye nememori. Ukusetyenziswa kwexesha elide, iAlpha GPC inokuba lukhetho olukhuselekileyo.
Phambi kokuba sijonge kwimiba yokhuseleko, kuyafuneka ukuqonda ukuba isebenza njani iAlpha GPC. Xa ifakwe, i-Alpha GPC iguqulwa ibe yi-choline, ekhuthaza ukuhlanganiswa kwe-acetylcholine. Le neurotransmitter idlala indima ebalulekileyo kwimisebenzi eyahlukeneyo yengqondo, kubandakanya ingqwalasela, ukufunda, kunye nenkumbulo. Izifundo ezininzi zibonise ukuba i-Alpha GPC inokuphucula ukusebenza kwengqondo, ngakumbi kubantu abadala kunye nabantu abanokukhubazeka kwengqondo.
Izifundo zeklinikhi kunye nokhuseleko
1. Izifundo zabantu
Izifundo ezininzi zeklinikhi ziye zaphanda ukhuseleko kunye nokusebenza kwe-Alpha GPC. Uphononongo olupapashwe kwi-International Journal yoPhando lwezoNyango lufumene ukuba ukuthatha i-1,200 mg ye-Alpha GPC imihla ngemihla yayinyamezeleke kakuhle. Imiphumo emibi echazwe ngabathathi-nxaxheba yayincinci kwaye incinci ngokubanzi, kubandakanywa intloko, isiyezi kunye neengxaki zesisu.
Olunye uphando olupapashwe kwi-Clinical Therapeutics luvavanye ukhuseleko lwexesha elide lwe-Alpha GPC kwizigulane ezine-Alzheimer's disease. Uphononongo lugqibe ekubeni i-Alpha GPC ikhuselekile ekusebenziseni ixesha elide, kungekho miphumo ebalulekileyo echazwe.
2. Uphando lwezilwanyana
Izifundo zezilwanyana zikwaxhasa ukhuseleko lwe-Alpha GPC. Uphando olupapashwe kwi-Food and Chemical Toxicology yafumanisa ukuba i-Alpha GPC ayizange ibangele naziphi na iziphumo ezinobuthi kwiigundane, nakwiidosi eziphezulu. Ezi ziphumo zibonisa ukuba iAlpha GPC inomda obanzi wokhuseleko, nto leyo eyenza ukuba ibe sisongezelelo esikhuselekileyo sokusetyenziswa kwabantu.
Ngubani omele amphephe iAlpha GPC?
Ngelixa iAlpha GPC ikhuselekile ngokubanzi kubantu abaninzi, abanye abantu kufuneka balumke:
1. Abasetyhini abakhulelweyo nabancancisayo: Kukho izifundo ezilinganiselweyo malunga nokhuseleko lwe-Alpha GPC kubasetyhini abakhulelweyo nabancancisayo. Kucetyiswa ukuba udibane nomboneleli wezempilo ngaphambi kokusebenzisa le ncediso.
2. Abantu abaneengxaki ze-cardiovascular: I-Alpha GPC inokuchaphazela uxinzelelo lwegazi kunye nesantya sentliziyo. Abantu abanesifo senhliziyo kufuneka badibane nomboneleli wezempilo ngaphambi kokusetyenziswa.
3. Abantu abasebenzisa amayeza: I-Alpha GPC inokunxibelelana namayeza athile, kuquka i-anticholinergics kunye ne-blood thinners. Ukuba usebenzisa amayeza, soloko uthetha nomboneleli wakho wezempilo.
1. Ubunyulu kunye noMgangatho
Ukucoceka kunye nomgangatho we-Alpha GPC powder kubaluleke kakhulu. Umgangatho ophezulu weAlpha GPC kufuneka ungabinazingcolisi kunye nezihluzi. Khangela iimveliso ezivavanywa ngumntu wesithathu ukucoceka kunye namandla. Iimpawu ezaziwayo zihlala zibonelela ngeSiqinisekiso sokuHlalutya (COA) ukuqinisekisa umgangatho wemveliso.
2. Umthamo kunye nokugxila
Izongezo ze-Alpha GPC ziyafumaneka kwiidosi ezahlukeneyo kunye noxinzelelo. Olona gxininiso luqhelekileyo luyi-50% kunye ne-99%. Ugxininiso lwe-99% lusebenza ngakumbi kwaye ludinga umthamo omncinci ukufezekisa umphumo oyifunayo. Nangona kunjalo, ikwabiza kakhulu. Cinga ngohlahlo lwabiwo-mali lwakho kunye namandla afunekayo xa ukhetha ugxininiso.
3. Ifom yemveliso
I-Alpha GPC ifumaneka ngeendlela ezahlukeneyo, kuquka umgubo, iipilisi, kunye nolwelo. Ifomu nganye ineenzuzo kunye nokungona kwayo. I-Alpha GPC yePowdered iyaguquguquka kwaye inokuxutywa ngokulula nezinye izongezo okanye iziselo. Iipilisi zilungele kwaye zilinganiswe kwangaphambili, zilungele ukuthatha uhambo. I-Liquid Alpha GPC ifunxa ngokukhawuleza kodwa inokuba nobomi obufutshane beshelufu. Khetha ifomathi eyifanele kakhulu indlela ophila ngayo kunye nezinto ozikhethayo.
4. Isidima sophawu
Isidima sophawu yinto ebalulekileyo ekufuneka iqwalaselwe. Iibrendi ezihloniphekileyo ezinophononongo oluhle lwabathengi kunokwenzeka ukuba zibonelele ngeemveliso ezikumgangatho ophezulu. Phanda ngembali yebhrendi, ingxelo yomthengi, kunye naziphi na iziqinisekiso abanokuba nazo. Ziphephe iibrendi ezinembali yokukhumbula okanye uphononongo olubi.
5. Ixabiso kunye nexabiso
Ixabiso lihlala liqwalaselwa xa kuthengwa izongezo. Nangona kunjalo, eyona ndlela inexabiso eliphantsi ayisoloko ilungile. Thelekisa amaxabiso ngegram nganye okanye ukugalela ukuze ubone elona xabiso lilungileyo lemali. Qwalasela umgangatho wemveliso, ukugxininiswa kwayo, kunye nazo naziphi na ezinye iingenelo enokukunika zona.
6. Ezinye izithako
Ezinye iimveliso ze-Alpha GPC zinokuqulatha ezinye izithako, ezifana nezinye i-nootropics, iivithamini okanye iiminerali. Ezi zithako zongeziweyo zinokuphucula ukusebenza ngokupheleleyo kwesongezo. Nangona kunjalo, bandisa umngcipheko wemiphumo emibi okanye ukusebenzisana namanye amayeza. Funda ileyibhile ngononophelo kwaye ubuze ingcali yezempilo ukuba unayo nayiphi na imibuzo.
7. Uphononongo lwabaThengi kunye noBungqina
Uphononongo lwabathengi kunye nobungqina bunokubonelela ngengqiqo ebalulekileyo ekusebenzeni kwemveliso kunye nomgangatho. Jonga uphononongo oluvela kubathengi abaqinisekisiweyo kwaye uqaphele nayiphi na imiba eqhubekayo okanye izincomo. Gcina ukhumbule ukuba amava ngamnye anokwahluka, kodwa iipatheni zempendulo ezilungileyo okanye ezimbi zingabonakalisa umgangatho opheleleyo wemveliso.
I-Suzhou Myland Pharm & Nutrition Inc. ngumvelisi obhalisiwe we-FDA obonelela ngomgangatho ophezulu kunye nococeko oluphezulu lwe-Alpha GPC powder.
ESuzhou Myland Pharm sizimisele ukubonelela ngezona mveliso zikumgangatho ophezulu ngamaxabiso angcono. Umgubo wethu we-Alpha GPC uvavanywa ngokungqongqo ubunyulu kunye namandla, ukuqinisekisa ukuba ufumana isongezelelo esikumgangatho ophezulu onokuthembela kuwo. Nokuba ufuna ukuxhasa impilo yeselula, ukomeleza amajoni akho omzimba okanye ukomeleza impilo yonke, umgubo wethu weAlpha GPC lolona khetho lufanelekileyo.
Ineminyaka engama-30 yamava kwaye iqhutywa bubuchwepheshe obuphezulu kunye nezicwangciso ze-R&D eziphuculwe kakhulu, iSuzhou Myland Pharm iphuhlise uluhlu lweemveliso ezikhuphisanayo kwaye ibe sisongezelelo sesayensi yobomi, ukudibanisa isiko kunye nenkampani yeenkonzo zokuvelisa.
Ukongeza, iSuzhou Myland Pharm ikwangumvelisi obhalisiweyo we-FDA. Izixhobo ze-R&D zenkampani, izixhobo zemveliso, kunye nezixhobo zohlalutyo zezanamhlanje kwaye zinemisebenzi emininzi, kwaye zinokuvelisa iikhemikhali ukusuka kwimilligrams ukuya kwiitoni kwisikali, kwaye zithobela imigangatho ye-ISO 9001 kunye neenkcukacha zemveliso ye-GMP.
Umbuzo: Yintoni i-Alpha-GPC?
A: I-Alpha-GPC (i-L-Alpha glycerylphosphorylcholine) yinto yendalo ye-choline efumaneka kwingqondo. Ikwafumaneka njengesongezelelo sokutya kwaye iyaziwa ngeempawu zayo zokuphucula ingqondo. I-Alpha-GPC ihlala isetyenziselwa ukuxhasa impilo yengqondo, ukuphucula imemori, kunye nokuphucula ukucaca kwengqondo.
Q:Isebenza njani iAlpha-GPC?
A: I-Alpha-GPC isebenza ngokwandisa amanqanaba e-acetylcholine engqondweni. I-Acetylcholine yi-neurotransmitter edlala indima ebalulekileyo ekwenziweni kwememori, ukufunda, kunye nokusebenza kwengqondo jikelele. Ngokunyusa amanqanaba e-acetylcholine, i-Alpha-GPC inokunceda ukuphucula ukusebenza kwengqondo kunye nokuxhasa impilo yengqondo.
Umbuzo:3. Ziziphi iingenelo zokuthatha i-Alpha-GPC?
A: Iinzuzo eziphambili zokuthatha i-Alpha-GPC ziquka:
-Uphuculo lwenkumbulo kunye nobuchule bokufunda
- Ukuphucula ukucaca kwengqondo kunye nokugxila
- Inkxaso kwimpilo yobuchopho ngokubanzi
-Iziphumo ezinokwenzeka ze-neuroprotective, ezinokunceda ekuthinteleni ukuncipha kwengqondo
- Ukonyuka kokusebenza komzimba, ngakumbi kwiimbaleki, ngenxa yendima yayo ekukhuthazeni ukukhululwa kwehomoni yokukhula
Ukuziphendulela: Eli nqaku lelolwazi ngokubanzi kuphela kwaye akufanele lithathwe njengeliphi na icebiso lonyango. Olunye ulwazi lweposti yebhlog luvela kwi-Intanethi kwaye alunamsebenzi. Le webhusayithi inoxanduva kuphela lokuhlela, ukufomatha kunye nokuhlela amanqaku. Injongo yokudlulisa ulwazi olongezelelekileyo ayithethi ukuba uyavumelana neembono zayo okanye uqinisekise ubunyani bomxholo wayo. Soloko udibana nengcali yezempilo ngaphambi kokuba usebenzise naziphi na izongezo okanye wenze utshintsho kwirejimeni yokhathalelo lwempilo.
Ixesha lokuposa: Sep-23-2024
