Ukusuka kwisiqabu soxinzelelo ukuya ekuPhulukisweni kwengqondo: Ukuphonononga ukuguquguquka kweSalidroside

I-Rhodiola rosea yingcambu eyomileyo kunye nesiqu se-Rhodiola rosea, isityalo se-Sedum yentsapho yaseCrassuaceae. Luhlobo lwamayeza esintu aseTibet. Ikhula kwiindawo eziphakamileyo nakwiindawo ezinemitha ye-ultraviolet enamandla. Ngenxa yokuguquguquka kwayo ixesha elide kwi-hypoxia, imimoya ebhudla ngamandla, ukoma, kunye nengqele ephezulu Imekobume enzima ngolo hlobo yokukhula kwendalo idale amandla ayo omelele kunye nokuguquguquka okubanzi kokusingqongileyo, kwaye inemisebenzi ekhethekileyo yomzimba.

Salidroside, njengemveliso yendalo, ineempembelelo ezinokubakho kwi-radioprotective. Ngokukhusela kunye nokuphucula umsebenzi we-EPCs, i-salidroside inokunciphisa umonakalo we-radiation kwizicubu zomntu. Uphando olongezelelweyo luya kunceda ukuveza indlela ye-radioprotective ye-salidroside kunye nokukhuthaza ukusetyenziswa kwayo kweklinikhi.

Uphononongo lufumene ukuba i-salidroside inamandla okuba neziphumo ze-radioprotective kwiiseli ze-endothelial progenitor (EPCs). I-EPCs ziyi-precursor cells of vascular endothelial cells kwaye zidlala indima ebalulekileyo ekuhlaziyweni nasekulungiseni i-vascular endothelium kunye nokwakhiwa kwemithambo yegazi emitsha kwizicubu ezonakalisiweyo. I-Salidroside inokukhusela ii-EPCs kumonakalo wemitha, ukuphucula umsebenzi wazo, ukubambelela kunye nokukwazi ukufuduka, kunye nokunciphisa i-apoptosis eyenziwa yi-radiation.

Ukongeza, i-salidroside inokuphucula impembelelo ye-radioprotective ye-EPCs ngokuvula i-PI3K/Akt indlela yokubonisa. Oku kufunyanisiweyo kunika isiseko sokusetyenziswa kwesalidroside njengeradioprotectant.

I-Salidroside ayibonisi nje kuphela amandla okukhusela i-radioprotection kodwa ineminye imisebenzi emininzi yebhayoloji. Kufunyenwe ukuxinwa kwe-anti-oxidative, i-anti-inflammatory, anti-fatigue, i-anti-aging kunye nemiphumo ye-neuroprotective. Ezi ziphumo zinokuthi zihambelane nokulawulwa kwe-metabolism yamandla eselula, uxinzelelo lwe-oxidative kunye nempendulo yokuvuvukala nge-salidroside.

1. Ukuchasana nokudumba

U-Yang Zelin kunye nabanye baseka imodeli yokulimala kwe-microglial ye-BV2 eyenziwa yi-LPS (lipopolysaccharide). Emva kokuba baphathwe ngeendlela ezahlukeneyo ze-salidroside, bafumanisa ukubonakaliswa kwe-cytokines IL-6, IL-1β, kunye ne-TNF-αmRNA ukujonga umphumo wokuchasana nokuvuvukala. .

2. I-Antioxidant

I-Rhodiola rosea inokuphucula amandla omzimba wokukhupha i-radicals yamahhala ngokunyusa umsebenzi we-antioxidant-related enzymes (SOD, GSH-Px kunye ne-CAT), ukunciphisa umsebenzi we-asidi phosphatase kunye nomxholo wokugqibela wokubola wemveliso ye-lipid peroxide (LPO) kunye nomxholo we-MDA. , ukunciphisa iqondo le-peroxidation ye-biofilms kunye nokukhusela iiseli zomzimba kunye nezicubu kumonakalo omkhulu wamahhala.

3. Ukuchasa ukuguga

Impembelelo yokuchasana ne-photoaging ye-Rhodiola rosea inokuba ngenxa yokuba i-Rhodiola rosea saponins inobudlelwane obuhle kunye nokungena kwi-stratum corneum yolusu, inokungena ngokufanelekileyo kuluhlu lwesikhumba, kwaye ikhutshwe ngokuthe ngcembe ukuze idlale indima yokulungisa. Ukongeza, i-saponins inokukhuthaza ukuvuselelwa kweeseli kunye nokukhuthaza ukukhula kwe-fibroblasts, ngaloo ndlela iphucula ukuqina kwesikhumba, ukulibazisa ukwenzeka kwemibimbi yolusu, kunye nokufezekisa injongo yokuchasa ukufota.

Apho ungafumana umgubo womgangatho ophezulu wesalidroside

Njengesithako esisebenzayo esibalulekileyo, i-salidroside ifumana ingqalelo ngakumbi nangakumbi. Ukuze kuhlangatyezwane neemfuno zophando lwezenzululwazi kunye neemarike zeemveliso zokhathalelo lwempilo, kubaluleke kakhulu ukukhetha umgangatho ophezulu we-salidroside powder.

I-Suzhou Myland yinkampani ejongene nophando, uphuhliso kunye nokuveliswa kwezinto ezidliwayo ezongezelelweyo zokutya, ezibophelele ekuboneleleni abathengi nge-high-purity salidroside powder. Inombolo ye-CAS yale mveliso yi-10338-51-9, kwaye ukucoceka kwayo kuphezulu njenge-98%, iqinisekisa ukuthembeka kwayo kunye nokusebenza kwayo kwiimvavanyo ezahlukeneyo kunye nezicelo.

Uphawu

Ukucoceka okuphezulu: Ukucoceka kwe-salidroside powder ye-Suzhou Myland ifikelela kwi-98%, oku kuthetha ukuba abasebenzisi banokufumana iziphumo zovavanyo ezichanekileyo nezingaguqukiyo ngexesha lokusetyenziswa. Iimveliso ezicocekileyo zinokunciphisa ngokufanelekileyo ukuphazamiseka kokungcola kwiimvavanyo kunye nokuqinisekisa ukuqina kophando.

UQinisekiso loMgangatho: Njengenkampani ye-biotechnology enamava atyebileyo, iSuzhou Myland ilandela ngokungqongqo imigangatho yamazwe ngamazwe yemveliso kunye nolawulo lomgangatho. Ibhetshi nganye yeemveliso ivavanywa ngokuqatha ukuqinisekisa ukuthotyelwa kwemigangatho efanelekileyo yomgangatho. Abathengi banokuyisebenzisa ngokuzithemba kwaye banciphise imingcipheko ebangelwa ziingxaki zomgangatho wemveliso.

I-Salidroside powder isetyenziswa ngokubanzi kwiinkalo ezininzi:

Iimveliso zokhathalelo lwempilo: Ngenxa yokuba i-salidroside ine-anti-fatigue, i-immunity-enhancing kunye nezinye iipropathi, ihlala isetyenziswa njengeyona nto iphambili kwiimveliso zokhathalelo lwempilo ukunceda abantu bomeleze imizimba yabo kwaye baxhathise uxinzelelo lwangaphandle.

Uphando oluchasene nokuguga: Njengoko iminyaka ikhula, amandla omzimba we-antioxidant ayancipha ngokuthe ngcembe. Njenge-antioxidant yendalo, i-salidroside icingelwa ukunceda ukucotha inkqubo yokuguga kunye nokuphucula ukusebenza kweeseli.

Izithambiso: Ngenxa yeempawu zayo ezilungileyo zokulwa ne-antioxidant, isalidroside ikwasetyenziswa kakhulu kwizithambiso ukunceda ukuphucula ukuthungwa kwesikhumba kunye nokumelana nomonakalo wokusingqongileyo eluswini.

Thenga amajelo

I-Suzhou Myland ibonelela ngeendlela zokuthenga kwi-intanethi ezifanelekileyo. Abathengi banokufaka iiodolo ngokuthe ngqo kwiwebhusayithi esemthethweni kwaye banandiphe iinkonzo zolungiselelo olukhawulezayo. Ukongeza, iqela leengcali zenkampani liya kubonelela abathengi ngenkxaso yobugcisa kunye neenkonzo zokubonisana ukunceda abathengi baqonde ngcono kwaye basebenzise iimveliso.