I-Calcium Alpha Ketoglutarate yi-compound enokuthi ikwazi ukulwa nenkqubo yokuguga. Indima yayo ekuphuculeni impilo ye-mitochondrial, ukubonelela nge-antioxidants, kunye nokuphucula imveliso ye-collagen yenza kube yinto enomdla kwabo bafuna ukugcina ukubonakala kolutsha. Njengoko uphando luqhubeka, kungekudala sinokutyhila ngakumbi izibonelelo zeCAKG.
I-Calcium Alpha-Ketoglutarate iyikhompawundi enamandla eyaziwa ngokuba yi-AKG Calcium edibanisa iCalcium kunye ne-Alpha-Ketoglutarate edlala indima ebalulekileyo kwiinkqubo ezininzi ze-biological Umjikelezo we-Krebs wethu Inkqubo apho umzimba uvelisa amandla, i-alpha-ketoglutarate iyona nto ibalulekileyo umjikelo weKrebs. I-calcium alpha-ketoglutarate iveliswa xa iiseli emzimbeni wethu ziqhekeza ukutya ukuze zibe namandla.
I-Calcium alpha-ketoglutarate ikwadlala indima ekubonakalisweni kofuzo njengendlela yokulawula ethintela iimpazamo zoshicilelo lwe-DNA ezihlala zikhokelela kwizifo ezinjengomhlaza.
Nangona iCalcium Alpha-Ketoglutarate iveliswa ngumzimba womntu, asinakuyifumana ngokuthe ngqo ngokutya. Sinokuyigcina ngokuzila ukutya kunye nokutya kwe-ketogenic, kodwa njengoko uphando oluqhubekayo lufumene ukuba ngokuncedisa i-Calcium Alpha-Ketoglutarate izongezelelo zokwandisa.
Iingenelo zempilo ezinokubakho zecalcium Calcium Alpha-Ketoglutarate:
●Ukuchasa ukuguga / Ukwandiswa koBomi
●Ukuphucula impilo yamathambo kwaye uthintele i-osteoporosis
●khupha ityhefu emzimbeni
●Ukuphucula ukusebenza kwamajoni omzimba
●Ukukhuthaza imetabolism
●Gcina impilo yentliziyo
1. I-Aids ekuchaseni ukuguga / ukwandisa ubomi
Kwizifundo ezinxulumeneyo, iCalcium Alpha-Ketoglutarate (CaAKG) ingqinwe ichasene nokuguga kwaye yandisa ubomi ukuya kuthi ga kwinqanaba elithile.
Njengoko sikhula, iiseli zethu zifumana iinguqu ezahlukeneyo zomzimba ezikhokelela kwiimpawu ezibonakalayo zokuguga. Ngokuncedisa imizimba yethu nge-CaAKG, sinakho ukucothisa le nkqubo.Ngokukodwa, i-mTOR inhibition ibonakala ikhuthaza ubomi obude beeseli kunye nokunciphisa umngcipheko wezifo ezinxulumene neminyaka ngokunyuka kwe-autophagy.
Uphando lubonisa ukuba ukuxhaswa kwe-CaAKG kunceda ukugcina impilo ye-mitochondrial, ephucula ukusebenza kweselula. I-Mitochondria zizixhobo zamandla zeeseli zethu ezinoxanduva lokuvelisa amandla, kwaye xa zisebenza ngokufanelekileyo, ukuguga kweselula kulibaziseka.
2. Ukuphucula impilo yamathambo kwaye uthintele i-osteoporosis
Kubantu abaninzi, ngenxa yokunyuka okuqhubekayo kweminyaka, amathambo aya kuba buthathaka kakhulu kwaye kulula ukuphuka. I-calcium iyona nxalenye enkulu yethambo kunye ne-alpha-ketoglutarate ibonakaliswe ukuba yanda (iprotein synthesis kunye nokuphucula ukubunjwa kwamathambo). Yiba negalelo ekufunxeni nasekusetyenzisweni komzimba. Ngokwandisa amanqanaba e-calcium, i-Ca-AKG inceda ukukhusela izifo ezifana ne-osteoporosis kunye ne-osteopenia, ezibaluleke kakhulu kubantwana nabadala.
3. Ukukhupha ityhefu emzimbeni
Enye inzuzo yezempilo ephawulekayo ye-calcium alpha-ketoglutarate yindima yayo ekupheliseni isibindi. Isibindi sesona sixhobo sokukhupha ubutyhefu emzimbeni wethu, kwaye ialpha-ketoglutarate inceda ukukhulisa amandla ayo okukhupha ubutyhefu. Ngokukhuthaza ukuveliswa kwe-glutathione, i-antioxidant enamandla, i-Ca-AKG inceda ukunciphisa i-toxins eyingozi kwaye ikhusela impilo yesibindi.
4. Ukuphucula ukusebenza kwamajoni omzimba
Ukugcina isistim somzimba esinamandla kubalulekile ukukhusela kwiintsholongwane ezinobungozi kunye nezifo. I-calcium alpha-ketoglutarate idlala indima ebalulekileyo ekuqinisekiseni ukusebenza kakuhle kokhuselo lomzimba. Ixhasa ukuveliswa kunye nomsebenzi wamajoni omzimba, ukuphucula iindlela zokukhusela.
5. Ukukhuthaza imetabolism
I-Alpha-ketoglutarate idlala indima ephambili ekulawuleni nasekugcineni imetabolism enempilo. Ngokukodwa, isantya apho iiseli zikhupha amandla kwiimolekyuli zokutya zixhomekeke kumanqanaba e-alpha-ketoglutarate ekhoyo. I-Alpha-ketoglutarate ibandakanyeka kumjikelezo we-tricarboxylic acid (umjikelezo we-TCA), inkqubo ephambili yokuvelisa amandla kwiiseli. Inceda ukunika amandla iiseli zakho eziwadingayo, oko konyusa imetabolism yakho.
6. Gcina impilo ye-cardiovascular
Ukugcina inkqubo ye-cardiovascular system enempilo kubalulekile kwimpilo yonke. I-calcium alpha-ketoglutarate inokuxhasa impilo yentliziyo ngokuxhasa ukusebenza kwemisipha egudileyo kunye nokulawula uxinzelelo lwegazi. Ikwanceda ukuphelisa izinto eziyingozi ezifana ne-ammonia emzimbeni, ukukhuthaza ngakumbi impilo yentliziyo.
I-calcium alpha-ketoglutarate (Ca-AKG) isebenza ngokuchaphazela iinkqubo ezahlukeneyo zebhayoloji emzimbeni. Ezi zilandelayo zezinye iindlela eziphambili zokwenza:
Yenza umjikelo we-TCA, ukhuthaze imetabolism
I-Ca-AKG yinto ephambili ephakathi kumjikelo we-tricarboxylic acid (TCA), owaziwa ngokuba ngumjikelo we-Krebs okanye umjikelo we-citric acid. Lo mjikelo udlala indima ebalulekileyo kwimveliso yamandla eselula. I-Ca-AKG inceda ukuququzelela ukuguqulwa kweemolekyuli zokutya zibe amandla, ngokukodwa ngendlela ye-adenosine triphosphate (ATP). Le nkqubo ibaluleke kakhulu kwi-metabolism jikelele.
ukwenza iprotein synthesis
I-Ca-AKG icingelwa ukuba ivuselele i-protein synthesis, ebalulekileyo ekukhuleni kwemisipha, ukulungiswa kunye nokugcinwa. Ngokuphucula imveliso yeprotheyini, ixhasa uphuhliso kunye nokugcinwa kwezicubu zomzimba.
I-Nitric oxide (NO) Imveliso
I-Ca-AKG nayo ibandakanyeka ekuveliseni i-nitric oxide, i-molecule edlala indima kwiinkqubo ezahlukeneyo ze-physiological, kuquka i-vasodilation (ukwandiswa kwemithambo yegazi). Ukonyuka kwemveliso ye-nitric oxide idibaniswe nokuphucula ukuhamba kwegazi, ukuhanjiswa kwe-oksijini, kunye nokuthatha izondlo zemisipha.
Iipropati ze-Antioxidant
I-Ca-AKG ikholelwa ukuba ineempawu ze-antioxidant ezinceda ukunciphisa uxinzelelo lwe-oxidative emzimbeni. Uxinzelelo lwe-oxidative olubangelwa ukungalingani phakathi kwe-radicals yamahhala kunye ne-antioxidants kunokukhokelela kumonakalo weselula kunye nokuvuvukala. Ngokubonelela ngenkxaso ye-antioxidant, i-Ca-AKG inokuba negalelo kwimpilo yonke ye-metabolic.
I-calcium alpha-ketoglutarate (i-Ca-AKG) yikhompawundi edibanisa i-calcium yeminerali ebalulekileyo kunye ne-molecule ye-alpha-ketoglutarate. I-Calcium alpha-ketoglutarate (Ca-AKG) yikhemikhali engapheliyo engenakufumaneka ngokuthe ngqo ekutyeni, kodwa ezinye izifundo zibonise ukuba inokuveliswa ngokutya kunye nendlela yokuphila.
Ukutya kwe-ketogenic kunokukhetha okulungileyo, ukudibanisa amafutha kunye neprotheni, kunye nokutya okunokulinganisela okubandakanya oku kutya, unokubonelela umzimba wakho ngeCa-AKG.
Nangona kunjalo, ukuthembela kuphela kwi-ketogenic yokutya kwe-calcium alpha-ketoglutarate kunezinye iingxaki. Okokuqala, ukufumana i-Ca-AKG ecetyiswayo yemihla ngemihla ekutyeni kuphela kunokuba ngumngeni, ngakumbi kubantu abanezithintelo zokutya okanye izinto abazithandayo. Kwakhona, ukuxinana kwe-Ca-AKG ekutyeni kunokwahluka, okwenza kube nzima ukulawula ukutya kwakho okuchanekileyo. Ekugqibeleni, iindlela zokupheka kunye nokulungiswa kokutya kunokuchaphazela kakhulu amanqanaba e-Ca-AKG, mhlawumbi ukunciphisa inani elinokufunxwa.
I-calcium alpha-ketoglutarate izongezo zibonelela ngendlela efanelekileyo nethembekileyo yokuqinisekisa ukuba ufumana izixa ezaneleyo zale khompawundi. Bahambisa isixa esingaguqukiyo sekhompawundi, sivumela ulawulo lwedosi oluchanekileyo. Oku kuluncedo ngakumbi kwiimbaleki nakubantu abaneenkxalabo zempilo ezithile abafuna iidosi eziphezulu ze-Ca-AKG ukuhlangabezana neemfuno zabo.
Ngelixa izongezelelo zinazo ezi zibonelelo, kusekho ezinye izilumkiso ekufuneka uzigcine engqondweni. Okokuqala, ulawulo lomgangatho lubaluleke kakhulu xa ukhetha isongezelelo se-Ca-AKG. Kwakhona, izongezo akufanele zithathe indawo yokutya okunempilo. Ukufumana izondlo eziyimfuneko ekutyeni okupheleleyo kuhlala kubalulekile ekugcineni ukutya okunesondlo kunye nempilo iyonke. Okokugqibela, ukubonisana nengcali yezempilo okanye i-dietitian ebhalisiweyo inokukunceda ukufumanisa idosi echanekileyo kwaye ikukhokele ekukhetheni eyona nkxaso ifanelekileyo kwiimfuno zakho zomntu ngamnye.
Kubaluleke kakhulu ukulandela idosi ecetyiswayo kwaye udibane nochwepheshe bezempilo ngaphambi kokuba uqalise nayiphi na irejimeni entsha yokongeza, ngakumbi ukuba unayo nayiphi na imeko yezonyango okanye uthatha amayeza. Ukwazi iziphumo ebezingalindelekanga ezinokubakho kunye nokuthatha amanyathelo okhuseleko ayimfuneko kuya kunceda ukuqinisekisa ukusetyenziswa okukhuselekileyo nokusebenzayo kwe-Ca-AKG.
Ukhuseleko
I-Ca-AKG ithathwa njengekhuselekile xa isetyenziswa njengoko kuyalelwe. Nangona kunjalo, kubalulekile ukulandela idosi ecetyiswayo ukukhusela nayiphi na imiphumo emibi enokubakho. Kuhlala kucetyiswa ukuba udibane nochwepheshe bezempilo ngaphambi kokuba uqalise nayiphi na irejimeni entsha yokuncedisa ukutya, ngakumbi ukuba unayo nayiphi na imbali yonyango esele ikhona okanye uthatha nawaphi na amayeza.
imiphumela
Nangona i-Ca-AKG ikhuselekile ngokubanzi, inokubangela iziphumo ebezingalindelekanga kwabanye abantu. Ezi ziphumo bezingalindelekanga zidla ngokuba buthathaka kwaye zezexeshana, kodwa kubalulekile ukuba uziqaphele. Ezinye iziphumo ebezingalindelekanga ezixeliweyo ziquka:
1.Iingxaki zesisu: Abanye abantu banokufumana ukungonwabi kokutya, kubandakanya isicaphucaphu, ukuqunjelwa, kunye norhudo. Ezi zimpawu zihlala ziphela emva kweentsuku ezimbalwa njengoko umzimba ulungelelanisa ukongeza.
2.Ukwalana: Kwiimeko ezinqabileyo, abanye abantu banokuba ne-aleji kwi-Ca-AKG. Iimpawu zisenokuquka irhashalala, ukurhawuzelelwa, ukudumba, ukuba nesiyezi, okanye ubunzima bokuphefumla. Ukuba kukho nayiphi na kwezi mpawu, qiniseka ukuba uyayeka ukusebenzisa kwaye ufune unyango olukhawulezileyo.
3.Ukusebenzisana neziyobisi: I-Ca-AKG inokunxibelelana namachiza athile, njenge-calcium channel blockers, antibiotics, okanye iziyobisi ezichaphazela ukujika kwegazi. Soloko udibana nengcali yezempilo ukuba uthatha nawaphi na amayeza ukuze uqinisekise ukuba akukho nxibelelwano lunokwenzeka.
4.Iingxaki zezintso: I-Ca-AKG iqulethe i-calcium, kwaye ukutya kakhulu kwe-calcium kunokubangela iingxaki zezintso kubantu abanesifo sezintso. Soloko udibana nengcali yezempilo phambi kokuba usebenzise i-Ca-AKG ukuba unayo naziphi na iingxaki ezinxulumene nezintso.
Kuyaphawuleka ukuba ezi ziphumo bezingalindelekanga zinqabile kwaye azibonwa ngabasebenzisi abaninzi. Nangona kunjalo, ukulumka kunye nokuphaphama kufuneka kuhlale kusenziwa xa ungenisa nasiphi na isongezelelo esitsha sokutya kwindlela yakho yemihla ngemihla.
Umbuzo: Ngaba iCalcium Alpha Ketoglutarate inokunceda ngokulahleka kwemisipha enxulumene nobudala?
A: Ewe, uphando lucebisa ukuba i-Ca-AKG inokunceda ekugcineni ubunzima bemisipha kunye namandla ahla ngokwemvelo ngokuguga. Inceda ekwandiseni iprotein synthesis, ngaloo ndlela ixhasa ukubuyiswa kwemisipha kunye nokunciphisa ukulahleka kwemisipha enxulumene nobudala.
Umbuzo: I-Calcium Alpha Ketoglutarate iyichaphazela njani impilo yamathambo?
A: I-Ca-AKG idlala indima ebalulekileyo ekugcineni impilo yamathambo ngokuvuselela i-osteoblasts, iiseli ezijongene nokwakhiwa kwamathambo. Inceda ekwandiseni ukuxinana kwamathambo kunye nokunciphisa umngcipheko we-osteoporosis, imeko edla ngokuhambelana nokwaluphala.
Ukuziphendulela: Eli nqaku lenzelwe iinjongo zolwazi kuphela kwaye akufanele lithathwe njengengcebiso yezonyango. Soloko udibana nengcali yezempilo phambi kokuba usebenzise naziphi na izongezo okanye utshintshe irejimeni yokhathalelo lwempilo yakho.
Ixesha lokuposa: Jul-19-2023
